Project name: Protein4D
Status: done
submitted: 2018-11-16 06:12:06, status changed: 2018-11-16 06:19:49
Settings
|
Chain sequence(s)
|
A: GPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIMDRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMESYVVHTNYDEYAIFLTKKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIFTMADRVNGLEQATQAGPFMKWTKARQVPSTMLTKDTNPGLGWPLGLVLLFTPLSCSVT
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4964
-
Maximal score value
-
1.7213
-
Average score
-
-0.7777
-
Total score value
-
-170.3163
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
G |
A |
-0.9812 |
|
| 2 |
P |
A |
-0.6665 |
|
| 3 |
V |
A |
0.4628 |
|
| 4 |
P |
A |
-0.2125 |
|
| 5 |
T |
A |
-0.8200 |
|
| 6 |
P |
A |
-0.7776 |
|
| 7 |
P |
A |
0.0000 |
|
| 8 |
D |
A |
-2.5713 |
|
| 9 |
N |
A |
-2.4246 |
|
| 10 |
I |
A |
-1.4549 |
|
| 11 |
Q |
A |
-1.9665 |
|
| 12 |
V |
A |
-1.6597 |
|
| 13 |
Q |
A |
-2.3169 |
|
| 14 |
E |
A |
-3.1193 |
|
| 15 |
N |
A |
-2.5491 |
|
| 16 |
F |
A |
0.0000 |
|
| 17 |
N |
A |
-1.8252 |
|
| 18 |
I |
A |
-1.2761 |
|
| 19 |
S |
A |
-1.3808 |
|
| 20 |
R |
A |
-2.4117 |
|
| 21 |
I |
A |
0.0000 |
|
| 22 |
Y |
A |
-1.2492 |
|
| 23 |
G |
A |
-1.5530 |
|
| 24 |
K |
A |
-1.6591 |
|
| 25 |
W |
A |
0.0000 |
|
| 26 |
Y |
A |
-0.6461 |
|
| 27 |
N |
A |
0.0000 |
|
| 28 |
L |
A |
0.0000 |
|
| 29 |
A |
A |
0.0000 |
|
| 30 |
I |
A |
0.0000 |
|
| 31 |
G |
A |
0.0000 |
|
| 32 |
S |
A |
0.0000 |
|
| 33 |
T |
A |
-0.2098 |
|
| 34 |
C |
A |
0.0000 |
|
| 35 |
P |
A |
-0.4917 |
|
| 36 |
W |
A |
-0.0367 |
|
| 37 |
L |
A |
0.0000 |
|
| 38 |
K |
A |
-1.7527 |
|
| 39 |
K |
A |
-2.3259 |
|
| 40 |
I |
A |
-1.7119 |
|
| 41 |
M |
A |
0.0000 |
|
| 42 |
D |
A |
-2.8715 |
|
| 43 |
R |
A |
-3.0429 |
|
| 44 |
M |
A |
-1.7636 |
|
| 45 |
T |
A |
-1.3656 |
|
| 46 |
V |
A |
0.0000 |
|
| 47 |
S |
A |
0.0000 |
|
| 48 |
T |
A |
0.0000 |
|
| 49 |
L |
A |
-0.0228 |
|
| 50 |
V |
A |
0.1496 |
|
| 51 |
L |
A |
0.0000 |
|
| 52 |
G |
A |
-1.0640 |
|
| 53 |
E |
A |
-2.2594 |
|
| 54 |
G |
A |
-1.6315 |
|
| 55 |
A |
A |
-0.8587 |
|
| 56 |
T |
A |
-1.3866 |
|
| 57 |
E |
A |
-2.3443 |
|
| 58 |
A |
A |
-1.4596 |
|
| 59 |
E |
A |
0.0000 |
|
| 60 |
I |
A |
0.0000 |
|
| 61 |
S |
A |
-0.6157 |
|
| 62 |
M |
A |
-0.0365 |
|
| 63 |
T |
A |
0.2708 |
|
| 64 |
S |
A |
0.0575 |
|
| 65 |
T |
A |
0.0000 |
|
| 66 |
R |
A |
0.0145 |
|
| 67 |
W |
A |
-0.2249 |
|
| 68 |
R |
A |
-1.2400 |
|
| 69 |
K |
A |
-2.0634 |
|
| 70 |
G |
A |
-0.8354 |
|
| 71 |
V |
A |
0.1277 |
|
| 72 |
C |
A |
-0.1374 |
|
| 73 |
E |
A |
0.0000 |
|
| 74 |
E |
A |
-0.0519 |
|
| 75 |
T |
A |
0.4759 |
|
| 76 |
S |
A |
0.6868 |
|
| 77 |
G |
A |
0.4217 |
|
| 78 |
A |
A |
-0.0657 |
|
| 79 |
Y |
A |
-0.3983 |
|
| 80 |
E |
A |
-1.3642 |
|
| 81 |
K |
A |
-1.7854 |
|
| 82 |
T |
A |
-1.6867 |
|
| 83 |
D |
A |
-2.3805 |
|
| 84 |
T |
A |
-2.0812 |
|
| 85 |
D |
A |
-2.6378 |
|
| 86 |
G |
A |
0.0000 |
|
| 87 |
K |
A |
-1.3522 |
|
| 88 |
F |
A |
0.0000 |
|
| 89 |
L |
A |
0.0000 |
|
| 90 |
Y |
A |
0.0000 |
|
| 91 |
H |
A |
-0.6775 |
|
| 92 |
K |
A |
0.0000 |
|
| 93 |
S |
A |
-1.3619 |
|
| 94 |
K |
A |
-2.0881 |
|
| 95 |
W |
A |
-1.0133 |
|
| 96 |
N |
A |
-1.3843 |
|
| 97 |
I |
A |
0.0000 |
|
| 98 |
T |
A |
-0.1422 |
|
| 99 |
M |
A |
0.1234 |
|
| 100 |
E |
A |
0.0000 |
|
| 101 |
S |
A |
-0.0248 |
|
| 102 |
Y |
A |
-0.3597 |
|
| 103 |
V |
A |
0.0000 |
|
| 104 |
V |
A |
0.0000 |
|
| 105 |
H |
A |
-1.4556 |
|
| 106 |
T |
A |
0.0000 |
|
| 107 |
N |
A |
-2.4196 |
|
| 108 |
Y |
A |
-2.5634 |
|
| 109 |
D |
A |
-3.4964 |
|
| 110 |
E |
A |
-2.7443 |
|
| 111 |
Y |
A |
-1.6746 |
|
| 112 |
A |
A |
0.0000 |
|
| 113 |
I |
A |
0.0000 |
|
| 114 |
F |
A |
0.0000 |
|
| 115 |
L |
A |
0.0000 |
|
| 116 |
T |
A |
0.0000 |
|
| 117 |
K |
A |
0.0000 |
|
| 118 |
K |
A |
-0.0307 |
|
| 119 |
F |
A |
-0.3756 |
|
| 120 |
S |
A |
0.0000 |
|
| 121 |
R |
A |
-2.7878 |
|
| 122 |
H |
A |
-2.4310 |
|
| 123 |
H |
A |
-2.0357 |
|
| 124 |
G |
A |
-1.0356 |
|
| 125 |
P |
A |
-0.3834 |
|
| 126 |
T |
A |
-0.1363 |
|
| 127 |
I |
A |
0.0000 |
|
| 128 |
T |
A |
-0.1396 |
|
| 129 |
A |
A |
0.0000 |
|
| 130 |
K |
A |
-0.2385 |
|
| 131 |
L |
A |
0.0000 |
|
| 132 |
Y |
A |
0.0000 |
|
| 133 |
G |
A |
0.0000 |
|
| 134 |
R |
A |
-2.9686 |
|
| 135 |
A |
A |
-1.7202 |
|
| 136 |
P |
A |
-1.2089 |
|
| 137 |
Q |
A |
-1.9820 |
|
| 138 |
L |
A |
-1.7164 |
|
| 139 |
R |
A |
-2.3632 |
|
| 140 |
E |
A |
-2.9663 |
|
| 141 |
T |
A |
-2.1243 |
|
| 142 |
L |
A |
-1.7187 |
|
| 143 |
L |
A |
-1.7867 |
|
| 144 |
Q |
A |
-2.3345 |
|
| 145 |
D |
A |
-2.1286 |
|
| 146 |
F |
A |
0.0000 |
|
| 147 |
R |
A |
-1.1352 |
|
| 148 |
V |
A |
0.1704 |
|
| 149 |
V |
A |
-0.1878 |
|
| 150 |
A |
A |
0.0000 |
|
| 151 |
Q |
A |
-0.9361 |
|
| 152 |
G |
A |
-0.8383 |
|
| 153 |
V |
A |
0.0000 |
|
| 154 |
G |
A |
-1.3289 |
|
| 155 |
I |
A |
0.0000 |
|
| 156 |
P |
A |
-1.8315 |
|
| 157 |
E |
A |
-2.3438 |
|
| 158 |
D |
A |
-2.4582 |
|
| 159 |
S |
A |
0.0000 |
|
| 160 |
I |
A |
-0.9858 |
|
| 161 |
F |
A |
-0.6377 |
|
| 162 |
T |
A |
-0.1143 |
|
| 163 |
M |
A |
0.0000 |
|
| 164 |
A |
A |
-1.1093 |
|
| 165 |
D |
A |
-1.3325 |
|
| 166 |
R |
A |
-1.4102 |
|
| 167 |
V |
A |
0.6588 |
|
| 168 |
N |
A |
0.2819 |
|
| 169 |
G |
A |
0.0000 |
|
| 170 |
L |
A |
0.7035 |
|
| 171 |
E |
A |
-1.1056 |
|
| 172 |
Q |
A |
-1.6680 |
|
| 173 |
A |
A |
-1.0617 |
|
| 174 |
T |
A |
-1.1916 |
|
| 175 |
Q |
A |
-1.3653 |
|
| 176 |
A |
A |
0.0000 |
|
| 177 |
G |
A |
-0.3459 |
|
| 178 |
P |
A |
0.0000 |
|
| 179 |
F |
A |
1.7213 |
|
| 180 |
M |
A |
0.0000 |
|
| 181 |
K |
A |
-0.0709 |
|
| 182 |
W |
A |
-0.5057 |
|
| 183 |
T |
A |
-1.1337 |
|
| 184 |
K |
A |
-1.7890 |
|
| 185 |
A |
A |
-1.4638 |
|
| 186 |
R |
A |
-1.4044 |
|
| 187 |
Q |
A |
-1.6019 |
|
| 188 |
V |
A |
-0.2320 |
|
| 189 |
P |
A |
-0.0956 |
|
| 190 |
S |
A |
-0.7512 |
|
| 191 |
T |
A |
-1.2877 |
|
| 192 |
M |
A |
-0.4176 |
|
| 193 |
L |
A |
0.0000 |
|
| 194 |
T |
A |
-1.2531 |
|
| 195 |
K |
A |
-2.5876 |
|
| 196 |
D |
A |
-2.0956 |
|
| 197 |
T |
A |
-1.3608 |
|
| 198 |
N |
A |
-2.2722 |
|
| 199 |
P |
A |
-1.0949 |
|
| 200 |
G |
A |
-1.0914 |
|
| 201 |
L |
A |
0.0000 |
|
| 202 |
G |
A |
0.0000 |
|
| 203 |
W |
A |
0.7906 |
|
| 204 |
P |
A |
0.0000 |
|
| 205 |
L |
A |
1.0207 |
|
| 206 |
G |
A |
0.0000 |
|
| 207 |
L |
A |
0.8865 |
|
| 208 |
V |
A |
0.9687 |
|
| 209 |
L |
A |
0.0000 |
|
| 210 |
L |
A |
0.0000 |
|
| 211 |
F |
A |
-0.0127 |
|
| 212 |
T |
A |
0.0000 |
|
| 213 |
P |
A |
0.0000 |
|
| 214 |
L |
A |
0.0000 |
|
| 215 |
S |
A |
0.0000 |
|
| 216 |
C |
A |
0.0000 |
|
| 217 |
S |
A |
0.1607 |
|
| 218 |
V |
A |
0.5354 |
|
| 219 |
T |
A |
0.0000 |
|