Project name: 5wt9:L

Chain sequence(s)	L: STGEIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPGQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPEDFAVYYCQQSSNWPRTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4519
• Maximal score value: 1.6671
• Average score: -0.8325
• Total score value: -179.8166

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
-2	S	L	-0.3621
-1	T	L	-0.7496
0	G	L	-1.3794
1	E	L	-2.0434
2	I	L	0.0000
3	V	L	0.3261
4	L	L	0.0000
5	T	L	-0.5788
6	Q	L	0.0000
7	S	L	-0.7955
8	P	L	-0.3600
9	A	L	-0.4836
10	T	L	-0.3726
11	L	L	-0.2210
12	S	L	-0.5534
13	L	L	-0.8633
14	S	L	-1.1758
15	P	L	-1.5523
16	G	L	-1.6999
17	E	L	-2.1572
18	R	L	-2.5716
19	A	L	0.0000
20	T	L	-0.6415
21	L	L	0.0000
22	S	L	-0.9292
23	C	L	0.0000
24	R	L	-2.4330
25	A	L	0.0000
26	S	L	-1.1451
27	Q	L	-1.7061
28	S	L	-1.2028
29	V	L	0.0000
30	S	L	-0.5587
31	S	L	-0.3902
32	Y	L	0.2296
33	L	L	0.0000
34	A	L	0.0000
35	W	L	0.0000
36	Y	L	0.1975
37	Q	L	0.0000
38	Q	L	-1.3025
39	K	L	-1.7263
40	P	L	-1.4955
41	G	L	-1.3946
42	Q	L	-1.9833
43	A	L	-1.2166
44	P	L	-1.2133
45	R	L	-1.3664
46	L	L	-0.1466
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.1661
50	D	L	-1.0149
51	A	L	0.0000
52	S	L	-1.0864
53	N	L	-1.5240
54	R	L	-1.7055
55	A	L	-0.9473
56	T	L	-0.6274
57	G	L	-0.7355
58	I	L	0.0000
59	P	L	-0.5321
60	A	L	-0.4647
61	R	L	-0.8830
62	F	L	0.0000
63	S	L	-0.7528
64	G	L	0.0000
65	S	L	-0.9173
66	G	L	-1.2704
67	S	L	-1.1034
68	G	L	-1.0938
69	T	L	-1.8147
70	D	L	-2.3442
71	F	L	0.0000
72	T	L	-0.8175
73	L	L	0.0000
74	T	L	-0.6097
75	I	L	0.0000
76	S	L	-1.3307
77	S	L	-1.6857
78	L	L	0.0000
79	E	L	-2.2049
80	P	L	-1.6362
81	E	L	-2.2886
82	D	L	0.0000
83	F	L	-0.7342
84	A	L	0.0000
85	V	L	-0.4916
86	Y	L	0.0000
87	Y	L	0.1051
88	C	L	0.0000
89	Q	L	0.3358
90	Q	L	0.0000
91	S	L	-0.4510
92	S	L	-0.6188
93	N	L	-1.1792
94	W	L	-0.4142
95	P	L	-1.0499
96	R	L	-1.5890
97	T	L	-0.3402
98	F	L	1.0854
99	G	L	0.0000
100	Q	L	-0.7347
101	G	L	-0.5312
102	T	L	0.0000
103	K	L	-1.0143
104	V	L	0.0000
105	E	L	0.0000
106	I	L	-0.6609
107	K	L	-1.1750
108	R	L	-0.8797
109	T	L	-0.0628
110	V	L	0.3886
111	A	L	-0.1056
112	A	L	-0.2157
113	P	L	0.0000
114	S	L	0.0373
115	V	L	0.5410
116	F	L	1.6358
117	I	L	1.4852
118	F	L	1.6671
119	P	L	-0.0818
120	P	L	-0.7097
121	S	L	-1.8056
122	D	L	-3.2652
123	E	L	-3.4519
124	Q	L	-2.5848
125	L	L	-2.4900
126	K	L	-3.1230
127	S	L	-2.0699
128	G	L	-1.2973
129	T	L	-1.2851
130	A	L	0.0000
131	S	L	0.0419
132	V	L	0.0000
133	V	L	0.8114
134	C	L	0.0000
135	L	L	0.6972
136	L	L	0.0000
137	N	L	-0.4235
138	N	L	-1.2432
139	F	L	0.0000
140	Y	L	0.0000
141	P	L	-1.6953
142	R	L	-2.9313
143	E	L	-3.1790
144	A	L	-2.2906
145	K	L	-2.4349
146	V	L	-1.0897
147	Q	L	-0.6499
148	W	L	0.0000
149	K	L	-0.5973
150	V	L	0.0000
151	D	L	-1.9785
152	N	L	-1.3951
153	A	L	-0.2772
154	L	L	0.6776
155	Q	L	-0.0740
156	S	L	-0.4130
157	G	L	-1.0346
158	N	L	-1.0253
159	S	L	-1.4671
160	Q	L	-2.3178
161	E	L	-2.3166
162	S	L	-1.1174
163	V	L	-0.7624
164	T	L	-1.2743
165	E	L	-2.3095
166	Q	L	-2.0485
167	D	L	-2.3081
168	S	L	-1.9114
169	K	L	-2.3959
170	D	L	-1.9077
171	S	L	-1.8416
172	T	L	0.0000
173	Y	L	0.0000
174	S	L	-1.0049
175	L	L	0.0000
176	S	L	-0.3634
177	S	L	0.0000
178	T	L	-0.6181
179	L	L	0.0000
180	T	L	-0.4952
181	L	L	-0.6937
182	S	L	-1.1105
183	K	L	-2.2206
184	A	L	-1.8557
185	D	L	-2.4775
186	Y	L	0.0000
187	E	L	-3.2309
188	K	L	-3.4446
189	H	L	-2.7347
190	K	L	-2.5918
191	V	L	-1.2108
192	Y	L	0.0000
193	A	L	0.0000
194	C	L	0.0000
195	E	L	-0.8701
196	V	L	0.0000
197	T	L	-1.2308
198	H	L	0.0000
199	Q	L	-1.7445
200	G	L	-0.4897
201	L	L	-0.2617
202	S	L	-0.4858
203	S	L	-0.4187
204	P	L	-0.5382
205	V	L	0.0136
206	T	L	-0.3706
207	K	L	-0.2741
208	S	L	-0.3170
209	F	L	-0.7978
210	N	L	-1.9887
211	R	L	-2.2926
212	G	L	-2.0147
213	E	L	-2.4944