Project name: 3eob:H

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGYSFTGHWMNWVRQAPGKGLEWVGMIHPSDSETRYNQKFKDRFTISVDKSKNTLYLQMNSLRAEDTAVYYCARGIYFYGTTYFDYWGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8502
• Maximal score value: 2.9149
• Average score: -0.5852
• Total score value: -125.8115

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9981
2	V	H	-0.7627
3	Q	H	-0.6991
4	L	H	0.0000
5	V	H	1.1392
6	E	H	0.0000
7	S	H	-0.4058
8	G	H	-0.9367
9	G	H	-0.7325
10	G	H	-0.3383
11	L	H	-0.0773
12	V	H	0.0000
13	Q	H	-1.7249
14	P	H	-1.6692
15	G	H	-1.5040
16	G	H	-1.2511
17	S	H	-1.3210
18	L	H	-1.1957
19	R	H	-2.0687
20	L	H	0.0000
21	S	H	-0.3043
22	C	H	0.0000
23	A	H	-0.1325
24	A	H	0.0000
25	S	H	-0.7698
26	G	H	-1.1992
27	Y	H	-0.5879
28	S	H	-0.4624
29	F	H	0.0000
30	T	H	-1.0671
31	G	H	-0.6324
32	H	H	-0.3405
33	W	H	-0.2226
34	M	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.4306
40	A	H	-1.1138
41	P	H	-1.1027
42	G	H	-1.4301
43	K	H	-2.0716
44	G	H	-1.0035
45	L	H	0.3500
46	E	H	-0.3050
47	W	H	0.0000
48	V	H	0.0000
49	G	H	0.0000
50	M	H	0.0000
51	I	H	0.0000
52	H	H	-1.5635
53	P	H	0.0000
54	S	H	-1.7566
55	D	H	-2.6399
56	S	H	-2.3118
57	E	H	-2.8254
58	T	H	-1.9619
59	R	H	-2.3556
60	Y	H	-1.9733
61	N	H	-2.2910
62	Q	H	-3.3096
63	K	H	-3.2705
64	F	H	0.0000
65	K	H	-3.8502
66	D	H	-3.4801
67	R	H	-2.3891
68	F	H	0.0000
69	T	H	-1.1729
70	I	H	0.0000
71	S	H	-0.7019
72	V	H	-0.9949
73	D	H	-1.9011
74	K	H	-2.8183
75	S	H	-2.0963
76	K	H	-2.6981
77	N	H	-2.2559
78	T	H	0.0000
79	L	H	0.0000
80	Y	H	-0.4311
81	L	H	0.0000
82	Q	H	-1.1332
83	M	H	0.0000
84	N	H	-1.6134
85	S	H	-1.4779
86	L	H	0.0000
87	R	H	-2.7952
88	A	H	-1.9569
89	E	H	-2.3970
90	D	H	0.0000
91	T	H	-0.8853
92	A	H	0.0000
93	V	H	0.2827
94	Y	H	0.0000
95	Y	H	0.3966
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0128
99	G	H	0.0000
100	I	H	1.3514
101	Y	H	2.0825
102	F	H	2.9149
103	Y	H	2.3498
104	G	H	0.8593
105	T	H	0.8458
106	T	H	1.1848
107	Y	H	1.3425
108	F	H	0.4164
109	D	H	-0.8987
110	Y	H	0.0442
111	W	H	0.2741
112	G	H	0.0991
113	Q	H	-0.7481
114	G	H	-0.1923
115	T	H	-0.0023
116	L	H	0.2902
117	V	H	0.0000
118	T	H	-0.5051
119	V	H	0.0000
120	S	H	-1.0618
121	S	H	-0.7436
122	A	H	-0.5078
123	S	H	-0.6498
124	T	H	-0.8645
125	K	H	-1.5322
126	G	H	-1.6713
127	P	H	0.0000
128	S	H	-0.2064
129	V	H	0.0000
130	F	H	1.3265
131	P	H	0.3351
132	L	H	0.7672
133	A	H	-0.2282
134	P	H	-0.3743
135	S	H	-0.2803
136	S	H	-0.3200
142	G	H	-0.6521
143	T	H	-0.5110
144	A	H	-0.3248
145	A	H	0.0749
146	L	H	0.0000
147	G	H	0.0000
148	C	H	0.0000
149	L	H	0.7653
150	V	H	0.0000
151	K	H	-0.6086
152	D	H	-0.9305
153	Y	H	0.0000
154	F	H	0.0000
155	P	H	0.0000
156	E	H	-0.5749
157	P	H	-0.5276
158	V	H	-0.3920
159	T	H	-0.3330
160	V	H	-0.3166
161	S	H	-0.5532
162	W	H	0.0000
163	N	H	-0.9573
164	S	H	-0.7166
165	G	H	-0.5015
166	A	H	-0.1973
167	L	H	0.0240
168	T	H	-0.2762
169	S	H	-0.3728
170	G	H	-0.5082
171	V	H	-0.1093
172	H	H	-0.6229
173	T	H	0.0915
174	F	H	0.8135
175	P	H	0.6834
176	A	H	1.1277
177	V	H	2.1942
178	L	H	1.7184
179	Q	H	-0.2913
180	S	H	-0.4027
181	S	H	-0.5819
182	G	H	-0.3790
183	L	H	-0.1483
184	Y	H	0.4457
185	S	H	0.4188
186	L	H	0.0000
187	S	H	0.6093
188	S	H	0.0000
189	V	H	0.3379
190	V	H	0.0000
191	T	H	-0.2717
192	V	H	0.0000
193	P	H	-0.4995
194	S	H	-0.5994
195	S	H	-0.6328
196	S	H	-0.6432
197	L	H	-0.7598
198	G	H	-1.1006
199	T	H	-0.8361
200	Q	H	-1.2880
201	T	H	-1.2970
202	Y	H	0.0000
203	I	H	-1.5944
204	C	H	0.0000
205	N	H	-1.7715
206	V	H	0.0000
207	N	H	-1.7779
208	H	H	0.0000
209	K	H	-2.6557
210	P	H	-1.5900
211	S	H	-1.8876
212	N	H	-2.5425
213	T	H	-2.1828
214	K	H	-2.7043
215	V	H	-1.8305
216	D	H	-2.7129
217	K	H	-2.1363
218	K	H	-2.4946
219	V	H	0.0000
220	E	H	-2.2268