Project name: 6cnr:L
Status: done
submitted: 2019-03-20 15:23:41, status changed: 2019-03-20 17:12:17
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRASQSISSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQSYSTPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6314
-
Maximal score value
-
1.5625
-
Average score
-
-0.7603
-
Total score value
-
-160.4238
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.1324 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.8456 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-1.1979 |
|
| 6 |
Q |
L |
-0.8087 |
|
| 7 |
S |
L |
-0.8957 |
|
| 8 |
P |
L |
-0.6453 |
|
| 9 |
S |
L |
-0.8591 |
|
| 10 |
S |
L |
-0.8842 |
|
| 11 |
L |
L |
-0.5242 |
|
| 12 |
S |
L |
-0.7958 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-0.3169 |
|
| 15 |
V |
L |
0.6197 |
|
| 16 |
G |
L |
-0.3878 |
|
| 17 |
D |
L |
-1.3026 |
|
| 18 |
R |
L |
-2.1781 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6130 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.8840 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.8075 |
|
| 25 |
A |
L |
-1.9415 |
|
| 26 |
S |
L |
-2.0288 |
|
| 27 |
Q |
L |
-2.1163 |
|
| 28 |
S |
L |
-1.0620 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
S |
L |
-0.1673 |
|
| 31 |
S |
L |
0.2426 |
|
| 32 |
Y |
L |
1.2607 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
N |
L |
0.7010 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.0240 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5136 |
|
| 39 |
K |
L |
-1.8537 |
|
| 40 |
P |
L |
-1.4860 |
|
| 41 |
G |
L |
-1.5715 |
|
| 42 |
K |
L |
-2.4340 |
|
| 43 |
A |
L |
-1.4797 |
|
| 44 |
P |
L |
-1.4345 |
|
| 45 |
K |
L |
-1.7250 |
|
| 46 |
L |
L |
-0.3016 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.9000 |
|
| 50 |
A |
L |
0.5569 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.0761 |
|
| 53 |
S |
L |
0.1453 |
|
| 54 |
L |
L |
0.3034 |
|
| 55 |
Q |
L |
-0.3593 |
|
| 56 |
S |
L |
-0.4657 |
|
| 57 |
G |
L |
-0.5628 |
|
| 58 |
V |
L |
-0.3824 |
|
| 59 |
P |
L |
-0.3732 |
|
| 60 |
S |
L |
-0.4596 |
|
| 61 |
R |
L |
-0.7983 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.3317 |
|
| 64 |
G |
L |
-0.2248 |
|
| 65 |
S |
L |
-0.7030 |
|
| 66 |
G |
L |
-1.1080 |
|
| 67 |
S |
L |
-0.8866 |
|
| 68 |
G |
L |
-1.0545 |
|
| 69 |
T |
L |
-1.7767 |
|
| 70 |
D |
L |
-2.2542 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.8042 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.6244 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.2917 |
|
| 77 |
S |
L |
-1.0063 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.9216 |
|
| 80 |
P |
L |
-0.7908 |
|
| 81 |
E |
L |
-1.8509 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-0.5758 |
|
| 84 |
A |
L |
-0.8996 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.1675 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
1.1779 |
|
| 92 |
Y |
L |
1.1423 |
|
| 93 |
S |
L |
0.2982 |
|
| 94 |
T |
L |
0.0590 |
|
| 95 |
P |
L |
0.1850 |
|
| 96 |
L |
L |
1.2244 |
|
| 97 |
T |
L |
0.7895 |
|
| 98 |
F |
L |
1.5625 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
G |
L |
-0.4324 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.6747 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-0.9606 |
|
| 106 |
I |
L |
-0.1839 |
|
| 107 |
K |
L |
-1.2063 |
|
| 108 |
R |
L |
-0.9876 |
|
| 109 |
T |
L |
-0.0988 |
|
| 110 |
V |
L |
0.4050 |
|
| 111 |
A |
L |
-0.0572 |
|
| 112 |
A |
L |
-0.2247 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1286 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.2061 |
|
| 117 |
I |
L |
1.1859 |
|
| 118 |
F |
L |
1.3848 |
|
| 119 |
P |
L |
-0.2677 |
|
| 120 |
P |
L |
-0.8703 |
|
| 121 |
S |
L |
-1.8147 |
|
| 122 |
D |
L |
-3.2139 |
|
| 123 |
E |
L |
-3.3963 |
|
| 124 |
Q |
L |
-2.4621 |
|
| 125 |
L |
L |
-2.5360 |
|
| 126 |
K |
L |
-2.9983 |
|
| 127 |
S |
L |
-1.9160 |
|
| 128 |
G |
L |
-1.3814 |
|
| 129 |
T |
L |
-1.1722 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0175 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.6809 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.4983 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5343 |
|
| 138 |
N |
L |
-1.2664 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.4993 |
|
| 142 |
R |
L |
-2.6274 |
|
| 143 |
E |
L |
-2.9726 |
|
| 144 |
A |
L |
-2.1308 |
|
| 145 |
K |
L |
-2.1216 |
|
| 146 |
V |
L |
-1.0630 |
|
| 147 |
Q |
L |
-0.7196 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.8533 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-2.1589 |
|
| 152 |
N |
L |
-1.5044 |
|
| 153 |
A |
L |
-0.4686 |
|
| 154 |
L |
L |
0.3580 |
|
| 155 |
Q |
L |
-0.2960 |
|
| 156 |
S |
L |
-0.4837 |
|
| 157 |
G |
L |
-1.0490 |
|
| 158 |
N |
L |
-1.0571 |
|
| 159 |
S |
L |
-1.4780 |
|
| 160 |
Q |
L |
-2.3269 |
|
| 161 |
E |
L |
-2.3401 |
|
| 162 |
S |
L |
-1.3368 |
|
| 163 |
V |
L |
-0.7353 |
|
| 164 |
T |
L |
-1.2573 |
|
| 165 |
E |
L |
-2.3493 |
|
| 166 |
Q |
L |
-2.0775 |
|
| 167 |
D |
L |
-2.4109 |
|
| 168 |
S |
L |
-1.9307 |
|
| 169 |
K |
L |
-2.3136 |
|
| 170 |
D |
L |
-1.7079 |
|
| 171 |
S |
L |
-1.8491 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.9900 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.4901 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.6633 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.5568 |
|
| 181 |
L |
L |
-0.7026 |
|
| 182 |
S |
L |
-1.0560 |
|
| 183 |
K |
L |
-2.0919 |
|
| 184 |
A |
L |
-1.8361 |
|
| 185 |
D |
L |
-2.4806 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.3244 |
|
| 188 |
K |
L |
-3.6314 |
|
| 189 |
H |
L |
-3.2915 |
|
| 190 |
K |
L |
-3.4898 |
|
| 191 |
V |
L |
-1.9656 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-0.9908 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-1.0148 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.2033 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.5071 |
|
| 200 |
G |
L |
-0.4409 |
|
| 201 |
L |
L |
-0.2559 |
|
| 202 |
S |
L |
-0.4834 |
|
| 203 |
S |
L |
-0.4358 |
|
| 204 |
P |
L |
-0.5439 |
|
| 205 |
V |
L |
0.0445 |
|
| 206 |
T |
L |
-0.3996 |
|
| 207 |
K |
L |
-0.3099 |
|
| 208 |
S |
L |
-0.6129 |
|
| 209 |
F |
L |
-1.0483 |
|
| 210 |
N |
L |
-2.6645 |
|
| 211 |
R |
L |
-3.4039 |
|