Project name: 5y9k:H

Chain sequence(s)	H: VQLQQSGAEVKKPGSSVRVSCKASGGTFNNNAINWVRQAPGQGLEWMGGIIPMFGTAKYSQNFQGRVAITADESTGTASMELSSLRSEDTAVYYCARSRDLLLFPHHALSPWGRGTMVTVSSASTKGPSVFPLAPGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9508
• Maximal score value: 2.8509
• Average score: -0.5483
• Total score value: -118.4258

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	V	H	0.9392
3	Q	H	-1.1203
4	L	H	0.0000
5	Q	H	-2.4781
6	Q	H	-1.6380
7	S	H	-1.3763
8	G	H	-1.1282
9	A	H	-0.8560
10	E	H	-1.1537
11	V	H	-0.8401
12	K	H	-1.5671
13	K	H	-2.4510
14	P	H	-2.2253
15	G	H	-1.6053
16	S	H	-1.2503
17	S	H	-1.3846
18	V	H	0.0000
19	R	H	-2.2421
20	V	H	0.0000
21	S	H	-1.2430
22	C	H	0.0000
23	K	H	-2.3487
24	A	H	0.0000
25	S	H	-1.0669
26	G	H	-0.8111
27	G	H	-1.0347
28	T	H	-1.2964
29	F	H	0.0000
30	N	H	-1.9528
31	N	H	-1.3431
32	N	H	-1.0222
33	A	H	-0.0452
34	I	H	0.0000
35	N	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.0442
39	Q	H	-0.4191
40	A	H	-0.9652
41	P	H	-0.9628
42	G	H	-1.1717
43	Q	H	-1.5645
44	G	H	-0.6676
45	L	H	0.7390
46	E	H	-0.0631
47	W	H	0.3060
48	M	H	0.0000
49	G	H	0.0000
50	G	H	0.0000
51	I	H	0.0000
52	I	H	0.3282
53	P	H	0.0000
54	M	H	0.6018
55	F	H	1.9444
56	G	H	0.5901
57	T	H	0.3414
58	A	H	-0.4546
59	K	H	-1.7653
60	Y	H	-1.3970
61	S	H	-1.5829
62	Q	H	-2.4564
63	N	H	-2.2536
64	F	H	0.0000
65	Q	H	-2.4465
66	G	H	-1.5519
67	R	H	-1.2420
68	V	H	0.0000
69	A	H	-0.9538
70	I	H	0.0000
71	T	H	-0.5701
72	A	H	-0.8206
73	D	H	-1.9953
74	E	H	-1.6885
75	S	H	-1.1944
76	T	H	-1.2613
77	G	H	0.0000
78	T	H	-1.5882
79	A	H	0.0000
80	S	H	-1.1032
81	M	H	0.0000
82	E	H	-1.5909
83	L	H	0.0000
84	S	H	-1.1248
85	S	H	-1.1719
86	L	H	0.0000
87	R	H	-2.9450
88	S	H	-2.3405
89	E	H	-2.4907
90	D	H	0.0000
91	T	H	-1.0265
92	A	H	0.0000
93	V	H	0.0804
94	Y	H	0.0000
95	Y	H	-0.1339
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	S	H	-0.3799
100	R	H	-0.7127
101	D	H	0.5141
102	L	H	2.0662
103	L	H	2.8509
104	L	H	2.5374
105	F	H	1.3563
106	P	H	0.5900
107	H	H	-0.8474
108	H	H	-1.0935
109	A	H	-0.5052
110	L	H	-0.0086
111	S	H	-0.1206
112	P	H	-0.0110
113	W	H	-0.3326
114	G	H	0.0000
115	R	H	-2.1020
116	G	H	-1.0658
117	T	H	0.0000
118	M	H	-0.2606
119	V	H	0.0000
120	T	H	0.0000
121	V	H	0.0000
122	S	H	-1.3782
123	S	H	-1.1623
124	A	H	-0.5181
125	S	H	-0.5943
126	T	H	-0.5800
127	K	H	-1.1004
128	G	H	-1.4971
129	P	H	-0.6929
130	S	H	-0.2393
131	V	H	0.0000
132	F	H	0.8114
133	P	H	-0.0200
134	L	H	0.1933
135	A	H	-0.8133
136	P	H	-0.6270
144	G	H	-0.6403
145	T	H	-0.4694
146	A	H	-0.2375
147	A	H	0.1069
148	L	H	0.0000
149	G	H	0.0000
150	C	H	0.0000
151	L	H	0.5878
152	V	H	0.0000
153	K	H	-0.4621
154	D	H	-0.4875
155	Y	H	0.0000
156	F	H	-0.1673
157	P	H	0.0000
158	E	H	-0.3789
159	P	H	-0.7033
160	V	H	-0.5373
161	T	H	-0.6811
162	V	H	-0.4216
163	S	H	-0.5244
164	W	H	0.0000
165	N	H	-0.7213
166	S	H	-0.6572
167	G	H	-0.4822
168	A	H	-0.2060
169	L	H	0.0505
170	T	H	-0.2653
171	S	H	-0.3528
172	G	H	-0.4569
173	V	H	0.0434
174	H	H	-0.3543
175	T	H	0.3175
176	F	H	1.2088
177	P	H	0.8549
178	A	H	1.3439
179	V	H	2.4639
180	L	H	2.1704
181	Q	H	0.7631
182	S	H	0.0950
183	S	H	-0.2007
184	G	H	0.2994
185	L	H	0.4209
186	Y	H	0.8439
187	S	H	0.6663
188	L	H	0.0000
189	S	H	0.6939
190	S	H	0.0000
191	V	H	0.4763
192	V	H	0.0000
193	T	H	-0.2452
194	V	H	0.0000
195	P	H	-0.5957
196	S	H	-0.5196
197	S	H	-0.6084
198	S	H	-0.5981
199	L	H	-0.8187
200	G	H	-0.9723
201	T	H	-0.8887
202	Q	H	-1.1857
203	T	H	-1.0315
204	Y	H	0.0000
205	I	H	-1.2413
206	C	H	0.0000
207	N	H	-1.6173
208	V	H	0.0000
209	N	H	-2.2611
210	H	H	0.0000
211	K	H	-2.9508
212	P	H	-1.7434
213	S	H	-1.8391
214	N	H	-2.5999
215	T	H	-2.3758
216	K	H	-2.8183
217	V	H	-1.7312
218	D	H	-2.5400
219	K	H	-1.8879
220	K	H	-2.2248
221	V	H	0.0000
222	E	H	-2.7716
223	P	H	-1.8167
224	K	H	-2.1809