| Chain sequence(s) |
A: ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNRAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ B: ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNRAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | A | A | -1.3422 | |
| 2 | T | A | -1.3519 | |
| 3 | K | A | -1.3485 | |
| 4 | A | A | 0.0000 | |
| 5 | V | A | 0.0000 | |
| 6 | C | A | 0.0000 | |
| 7 | V | A | -0.2177 | |
| 8 | L | A | 0.0000 | |
| 9 | K | A | -1.9684 | |
| 10 | G | A | -2.0754 | |
| 11 | D | A | -2.5419 | |
| 12 | G | A | -1.8234 | |
| 13 | P | A | -1.6896 | |
| 14 | V | A | 0.0000 | |
| 15 | Q | A | -2.0890 | |
| 16 | G | A | -1.1580 | |
| 17 | I | A | 0.0010 | |
| 18 | I | A | 0.0000 | |
| 19 | N | A | -0.3109 | |
| 20 | F | A | 0.0000 | |
| 21 | E | A | -2.0198 | |
| 22 | Q | A | 0.0000 | |
| 23 | K | A | -3.1771 | |
| 24 | E | A | -3.2295 | |
| 25 | S | A | -2.2156 | |
| 26 | N | A | -2.2511 | |
| 27 | G | A | -2.1756 | |
| 28 | P | A | -1.9206 | |
| 29 | V | A | 0.0000 | |
| 30 | K | A | -2.4035 | |
| 31 | V | A | 0.0000 | |
| 32 | W | A | -0.6348 | |
| 33 | G | A | -0.2478 | |
| 34 | S | A | -1.0991 | |
| 35 | I | A | 0.0000 | |
| 36 | K | A | -2.6257 | |
| 37 | G | A | -1.8586 | |
| 38 | L | A | 0.0000 | |
| 39 | T | A | -2.1678 | |
| 40 | E | A | -3.0113 | |
| 41 | G | A | -1.3873 | |
| 42 | L | A | -0.3659 | |
| 43 | H | A | 0.0000 | |
| 44 | G | A | 0.0000 | |
| 45 | F | A | 0.0000 | |
| 46 | H | A | 0.0000 | |
| 47 | V | A | 0.0000 | |
| 48 | H | A | 0.0000 | |
| 49 | E | A | -0.7785 | |
| 50 | F | A | -0.3879 | |
| 51 | G | A | 0.0000 | |
| 52 | D | A | 0.0000 | |
| 53 | N | A | -0.5780 | |
| 54 | R | A | -0.8323 | |
| 55 | A | A | -0.5383 | |
| 56 | G | A | -1.0975 | |
| 57 | C | A | -0.7945 | |
| 58 | T | A | -0.4695 | |
| 59 | S | A | -0.6423 | |
| 60 | A | A | 0.0000 | |
| 61 | G | A | -0.5323 | |
| 62 | P | A | -0.6407 | |
| 63 | H | A | 0.0000 | |
| 64 | F | A | 0.0000 | |
| 65 | N | A | -1.0513 | |
| 66 | P | A | -0.7050 | |
| 67 | L | A | -0.7039 | |
| 68 | S | A | -1.4056 | |
| 69 | R | A | -3.3501 | |
| 70 | K | A | -3.5452 | |
| 71 | H | A | 0.0000 | |
| 72 | G | A | 0.0000 | |
| 73 | G | A | 0.0000 | |
| 74 | P | A | -1.8125 | |
| 75 | K | A | -2.7934 | |
| 76 | D | A | -3.2304 | |
| 77 | E | A | -3.8856 | |
| 78 | E | A | -4.1076 | |
| 79 | R | A | 0.0000 | |
| 80 | H | A | 0.0000 | |
| 81 | V | A | 0.0000 | |
| 82 | G | A | 0.0000 | |
| 83 | D | A | 0.0000 | |
| 84 | L | A | 0.0000 | |
| 85 | G | A | 0.0000 | |
| 86 | N | A | -0.2566 | |
| 87 | V | A | 0.0000 | |
| 88 | T | A | -0.9151 | |
| 89 | A | A | 0.0000 | |
| 90 | D | A | -3.2217 | |
| 91 | K | A | -3.6373 | |
| 92 | D | A | -3.5008 | |
| 93 | G | A | 0.0000 | |
| 94 | V | A | -2.5390 | |
| 95 | A | A | 0.0000 | |
| 96 | D | A | -2.1497 | |
| 97 | V | A | 0.0000 | |
| 98 | S | A | -0.9962 | |
| 99 | I | A | -0.9809 | |
| 100 | E | A | -2.2595 | |
| 101 | D | A | 0.0000 | |
| 102 | S | A | -1.0408 | |
| 103 | V | A | -0.4388 | |
| 104 | I | A | 0.0000 | |
| 105 | S | A | -1.0507 | |
| 106 | L | A | 0.0000 | |
| 107 | S | A | -1.1485 | |
| 108 | G | A | -1.5926 | |
| 109 | D | A | -2.0432 | |
| 110 | H | A | -1.0686 | |
| 111 | C | A | -0.7353 | |
| 112 | I | A | 0.0000 | |
| 113 | I | A | 0.0000 | |
| 114 | G | A | 0.0000 | |
| 115 | R | A | -0.1583 | |
| 116 | T | A | 0.0000 | |
| 117 | L | A | 0.0000 | |
| 118 | V | A | 0.0000 | |
| 119 | V | A | 0.0000 | |
| 120 | H | A | 0.0000 | |
| 121 | E | A | -1.6618 | |
| 122 | K | A | -2.2225 | |
| 123 | A | A | -0.9781 | |
| 124 | D | A | 0.0000 | |
| 125 | D | A | -1.4792 | |
| 126 | L | A | -1.1940 | |
| 127 | G | A | -2.5653 | |
| 128 | K | A | -2.3276 | |
| 129 | G | A | -2.4757 | |
| 130 | G | A | -2.3989 | |
| 131 | N | A | -3.2776 | |
| 132 | E | A | -3.4089 | |
| 133 | E | A | -3.0385 | |
| 134 | S | A | 0.0000 | |
| 135 | T | A | -3.1812 | |
| 136 | K | A | -3.0799 | |
| 137 | T | A | -1.8008 | |
| 138 | G | A | 0.0000 | |
| 139 | N | A | -2.2743 | |
| 140 | A | A | 0.0000 | |
| 141 | G | A | -1.5611 | |
| 142 | S | A | -1.1676 | |
| 143 | R | A | -1.1819 | |
| 144 | L | A | -1.2296 | |
| 145 | A | A | 0.0000 | |
| 146 | C | A | 0.0000 | |
| 147 | G | A | 0.0000 | |
| 148 | V | A | 0.2488 | |
| 149 | I | A | 0.0000 | |
| 150 | G | A | 0.0000 | |
| 151 | I | A | -0.2176 | |
| 152 | A | A | 0.0000 | |
| 153 | Q | A | -1.3482 | |
| 1 | A | B | -1.5620 | |
| 2 | T | B | -1.4178 | |
| 3 | K | B | -1.4590 | |
| 4 | A | B | 0.0000 | |
| 5 | V | B | 0.0000 | |
| 6 | C | B | 0.0000 | |
| 7 | V | B | -0.4170 | |
| 8 | L | B | 0.0000 | |
| 9 | K | B | -2.4270 | |
| 10 | G | B | -2.3276 | |
| 11 | D | B | -2.6426 | |
| 12 | G | B | -1.9063 | |
| 13 | P | B | -1.7414 | |
| 14 | V | B | 0.0000 | |
| 15 | Q | B | -2.2865 | |
| 16 | G | B | -1.2597 | |
| 17 | I | B | -0.1567 | |
| 18 | I | B | 0.0000 | |
| 19 | N | B | -0.4047 | |
| 20 | F | B | 0.0000 | |
| 21 | E | B | -2.1804 | |
| 22 | Q | B | 0.0000 | |
| 23 | K | B | -3.2445 | |
| 24 | E | B | -3.3425 | |
| 25 | S | B | -2.3027 | |
| 26 | N | B | -2.3789 | |
| 27 | G | B | -2.2093 | |
| 28 | P | B | -1.9821 | |
| 29 | V | B | 0.0000 | |
| 30 | K | B | -2.3003 | |
| 31 | V | B | 0.0000 | |
| 32 | W | B | -0.6789 | |
| 33 | G | B | -0.3354 | |
| 34 | S | B | -1.1027 | |
| 35 | I | B | 0.0000 | |
| 36 | K | B | -2.6286 | |
| 37 | G | B | -1.8355 | |
| 38 | L | B | 0.0000 | |
| 39 | T | B | -2.1817 | |
| 40 | E | B | -3.1360 | |
| 41 | G | B | -1.3024 | |
| 42 | L | B | -0.1812 | |
| 43 | H | B | 0.0000 | |
| 44 | G | B | 0.0000 | |
| 45 | F | B | 0.0000 | |
| 46 | H | B | 0.0000 | |
| 47 | V | B | 0.0000 | |
| 48 | H | B | 0.0000 | |
| 49 | E | B | -0.8706 | |
| 50 | F | B | 0.0000 | |
| 51 | G | B | 0.0000 | |
| 52 | D | B | 0.0000 | |
| 53 | N | B | -0.4449 | |
| 54 | R | B | -0.5941 | |
| 55 | A | B | -0.3313 | |
| 56 | G | B | -0.9824 | |
| 57 | C | B | -0.8178 | |
| 58 | T | B | -0.4197 | |
| 59 | S | B | -0.5860 | |
| 60 | A | B | 0.0000 | |
| 61 | G | B | -0.5840 | |
| 62 | P | B | -0.7090 | |
| 63 | H | B | 0.0000 | |
| 64 | F | B | 0.0000 | |
| 65 | N | B | -0.8285 | |
| 66 | P | B | -0.4468 | |
| 67 | L | B | 0.1132 | |
| 68 | S | B | -0.6326 | |
| 69 | R | B | -2.0490 | |
| 70 | K | B | -2.8018 | |
| 71 | H | B | 0.0000 | |
| 72 | G | B | 0.0000 | |
| 73 | G | B | 0.0000 | |
| 74 | P | B | -1.5826 | |
| 75 | K | B | -2.4956 | |
| 76 | D | B | -2.5658 | |
| 77 | E | B | -3.1223 | |
| 78 | E | B | -2.7355 | |
| 79 | R | B | 0.0000 | |
| 80 | H | B | 0.0000 | |
| 81 | V | B | 0.0000 | |
| 82 | G | B | 0.0000 | |
| 83 | D | B | 0.0000 | |
| 84 | L | B | 0.0000 | |
| 85 | G | B | 0.0000 | |
| 86 | N | B | -0.1874 | |
| 87 | V | B | 0.0000 | |
| 88 | T | B | -0.8256 | |
| 89 | A | B | 0.0000 | |
| 90 | D | B | -3.3984 | |
| 91 | K | B | -3.7417 | |
| 92 | D | B | -3.5802 | |
| 93 | G | B | 0.0000 | |
| 94 | V | B | -2.5436 | |
| 95 | A | B | 0.0000 | |
| 96 | D | B | -2.1291 | |
| 97 | V | B | 0.0000 | |
| 98 | S | B | -0.9744 | |
| 99 | I | B | -1.0711 | |
| 100 | E | B | -2.2192 | |
| 101 | D | B | 0.0000 | |
| 102 | S | B | -1.0800 | |
| 103 | V | B | -0.5035 | |
| 104 | I | B | 0.0000 | |
| 105 | S | B | -1.1423 | |
| 106 | L | B | 0.0000 | |
| 107 | S | B | -1.1997 | |
| 108 | G | B | -1.6334 | |
| 109 | D | B | -2.1494 | |
| 110 | H | B | -1.1167 | |
| 111 | C | B | -0.7895 | |
| 112 | I | B | 0.0000 | |
| 113 | I | B | 0.0000 | |
| 114 | G | B | 0.0000 | |
| 115 | R | B | -0.2442 | |
| 116 | T | B | 0.0000 | |
| 117 | L | B | 0.0000 | |
| 118 | V | B | 0.0000 | |
| 119 | V | B | 0.0000 | |
| 120 | H | B | 0.0000 | |
| 121 | E | B | -1.9574 | |
| 122 | K | B | -2.1063 | |
| 123 | A | B | -0.7682 | |
| 124 | D | B | 0.0000 | |
| 125 | D | B | -1.3623 | |
| 126 | L | B | -1.2396 | |
| 127 | G | B | -2.5536 | |
| 128 | K | B | -2.2761 | |
| 129 | G | B | -2.3012 | |
| 130 | G | B | -2.3047 | |
| 131 | N | B | -3.3037 | |
| 132 | E | B | -3.6231 | |
| 133 | E | B | -3.4384 | |
| 134 | S | B | 0.0000 | |
| 135 | T | B | -3.1029 | |
| 136 | K | B | -3.2946 | |
| 137 | T | B | -1.8692 | |
| 138 | G | B | 0.0000 | |
| 139 | N | B | -1.9149 | |
| 140 | A | B | 0.0000 | |
| 141 | G | B | -1.3947 | |
| 142 | S | B | -1.2055 | |
| 143 | R | B | -1.3027 | |
| 144 | L | B | -1.4889 | |
| 145 | A | B | 0.0000 | |
| 146 | C | B | 0.0000 | |
| 147 | G | B | -0.4346 | |
| 148 | V | B | 0.2215 | |
| 149 | I | B | 0.0000 | |
| 150 | G | B | 0.0000 | |
| 151 | I | B | -0.1132 | |
| 152 | A | B | 0.0000 | |
| 153 | Q | B | -1.3000 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine