Project name: 1F2 Aggrescan 3D

Chain sequence(s)	A: MTPLLALLGAALCSLTASAEVVPLADFDLQAMAGKWYLIGFATNAQWFVTRKATMKMGTAMLTPTAEGDLDLSYSSLSSDGSCWRKNNVAKKTDVPGQFTYVCQRYGSVNDMRVVDAKYDEYALVHTTKKKNGEISTVTKLYGRGEEVGANVMEKFRQLASEAGTLPENIVFLPKNAELPLLWKRSFIKATGINNSPLSPPSWHHE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2487
• Maximal score value: 1.5333
• Average score: -0.5531
• Total score value: -113.9308

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	1.2276
2	T	A	0.3006
3	P	A	0.7133
4	L	A	0.0000
5	L	A	0.0000
6	A	A	1.1762
7	L	A	1.4277
8	L	A	0.0000
9	G	A	1.1338
10	A	A	1.2577
11	A	A	0.0000
12	L	A	0.0300
13	C	A	0.5708
14	S	A	0.9922
15	L	A	1.5333
16	T	A	0.6074
17	A	A	0.0000
18	S	A	0.0000
19	A	A	-0.2057
20	E	A	-1.1178
21	V	A	0.0278
22	V	A	1.4088
23	P	A	0.5587
24	L	A	-0.2026
25	A	A	-0.4942
26	D	A	-1.9835
27	F	A	0.0000
28	D	A	-2.0747
29	L	A	-1.2861
30	Q	A	-1.5394
31	A	A	-1.3652
32	M	A	0.0000
33	A	A	-0.6709
34	G	A	-0.6205
35	K	A	-0.7085
36	W	A	0.0000
37	Y	A	-0.7197
38	L	A	0.0000
39	I	A	0.0000
40	G	A	0.0000
41	F	A	0.0000
42	A	A	0.0000
43	T	A	0.0000
44	N	A	0.0211
45	A	A	-0.2104
46	Q	A	-0.6022
47	W	A	0.6351
48	F	A	0.7814
49	V	A	-0.3191
50	T	A	-0.4943
51	R	A	-1.4339
52	K	A	-0.8177
53	A	A	-0.4102
54	T	A	-0.7942
55	M	A	-0.3250
56	K	A	-0.8647
57	M	A	0.0000
58	G	A	0.0000
59	T	A	0.0000
60	A	A	0.0000
61	M	A	-0.0071
62	L	A	0.0000
63	T	A	-0.4027
64	P	A	-0.8724
65	T	A	-0.8310
66	A	A	-0.9668
67	E	A	-2.0534
68	G	A	-1.7906
69	D	A	-1.2168
70	L	A	0.0000
71	D	A	-0.2811
72	L	A	0.0000
73	S	A	-0.2042
74	Y	A	0.1909
75	S	A	0.0000
76	S	A	0.1458
77	L	A	-0.2114
78	S	A	-0.7135
79	S	A	-1.1914
80	D	A	-2.1094
81	G	A	-1.3385
82	S	A	0.0000
83	C	A	0.0000
84	W	A	0.5325
85	R	A	0.0000
86	K	A	-0.2638
87	N	A	0.0000
88	N	A	0.0000
89	V	A	-0.2909
90	A	A	0.0000
91	K	A	-1.0992
92	K	A	-1.2583
93	T	A	-0.9548
94	D	A	-1.4943
95	V	A	-0.1707
96	P	A	-0.8146
97	G	A	0.0000
98	Q	A	-0.2152
99	F	A	0.0000
100	T	A	-0.0767
101	Y	A	0.0000
102	V	A	0.2358
103	C	A	0.0000
104	Q	A	-1.0153
105	R	A	-1.4717
106	Y	A	0.1064
107	G	A	0.0000
108	S	A	-0.2239
109	V	A	0.2341
110	N	A	0.0111
111	D	A	0.0000
112	M	A	0.0000
113	R	A	0.0000
114	V	A	0.0000
115	V	A	0.0000
116	D	A	-0.3344
117	A	A	0.0000
118	K	A	-2.6341
119	Y	A	-2.2355
120	D	A	-2.9800
121	E	A	-2.9820
122	Y	A	-1.5642
123	A	A	0.0000
124	L	A	0.0000
125	V	A	0.0000
126	H	A	0.0000
127	T	A	0.0000
128	T	A	0.0000
129	K	A	-0.8178
130	K	A	-1.3316
131	K	A	-1.8906
132	N	A	-2.3766
133	G	A	-1.7891
134	E	A	-2.3048
135	I	A	0.0000
136	S	A	-0.4680
137	T	A	0.0000
138	V	A	0.0000
139	T	A	0.0000
140	K	A	-0.1292
141	L	A	0.0000
142	Y	A	0.0000
143	G	A	0.0000
144	R	A	-2.0734
145	G	A	-1.9311
146	E	A	-2.1925
147	E	A	-2.6664
148	V	A	-1.5499
149	G	A	-1.6549
150	A	A	-1.5172
151	N	A	-2.1265
152	V	A	0.0000
153	M	A	0.0000
154	E	A	-3.2487
155	K	A	-2.5209
156	F	A	0.0000
157	R	A	-2.3583
158	Q	A	-2.8461
159	L	A	-1.8200
160	A	A	0.0000
161	S	A	-1.2176
162	E	A	-1.9035
163	A	A	0.0000
164	G	A	0.0000
165	T	A	0.0000
166	L	A	0.4282
167	P	A	-0.8281
168	E	A	-1.5793
169	N	A	-0.5106
170	I	A	0.0000
171	V	A	0.0000
172	F	A	1.4423
173	L	A	0.0000
174	P	A	-0.8706
175	K	A	-2.3911
176	N	A	-1.7824
177	A	A	-0.8469
178	E	A	-0.6967
179	L	A	0.2966
180	P	A	0.3507
181	L	A	0.8730
182	L	A	0.0000
183	W	A	-0.1504
184	K	A	-1.6704
185	R	A	-2.0229
186	S	A	0.0000
187	F	A	-0.2197
188	I	A	-0.7032
189	K	A	-1.5789
190	A	A	0.0000
191	T	A	-0.8506
192	G	A	0.0000
193	I	A	-0.7489
194	N	A	-1.8238
195	N	A	-2.1498
196	S	A	-1.6239
197	P	A	-1.7582
198	L	A	-1.4993
199	S	A	-1.5480
200	P	A	0.0000
201	P	A	-1.6992
202	S	A	0.0000
203	W	A	-0.0978
204	H	A	-1.1804
205	H	A	-2.0391
206	E	A	-2.0464