Project name: 4np4:H

Chain sequence(s)	H: EVQLVQSGAEVKKSGESLKISCKGSGYSFTSYWIGWVRQMPGKGLEWMGIFYPGDSSTRYSPSFQGQVTISADKSVNTAYLQWSSLKASDTAMYYCARRRNWGNAFDIWGQGTMVTVSSASTKGPSVFPLAPSSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.965
• Maximal score value: 2.4227
• Average score: -0.6052
• Total score value: -130.1087

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1656
2	V	H	-1.3790
3	Q	H	-1.3452
4	L	H	0.0000
5	V	H	0.8532
6	Q	H	0.0000
7	S	H	-0.4160
8	G	H	-0.3532
9	A	H	-0.0472
10	E	H	-0.1445
11	V	H	0.5486
12	K	H	-0.9183
13	K	H	-1.8761
14	S	H	-1.8768
15	G	H	-1.9433
16	E	H	-2.0740
17	S	H	-1.7782
18	L	H	0.0000
19	K	H	-2.0294
20	I	H	0.0000
21	S	H	-0.5422
22	C	H	0.0000
23	K	H	-0.6538
24	G	H	0.0000
25	S	H	-0.9855
26	G	H	-1.2980
27	Y	H	-0.6557
28	S	H	-0.3412
29	F	H	0.0000
30	T	H	-0.6805
31	S	H	-0.6387
32	Y	H	-0.3470
33	W	H	-0.4861
34	I	H	0.0000
35	G	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.2418
39	Q	H	-0.5338
40	M	H	-0.7379
41	P	H	-1.0376
42	G	H	-1.5212
43	K	H	-2.0599
44	G	H	-0.9554
45	L	H	0.5909
46	E	H	-0.2366
47	W	H	0.4956
48	M	H	0.0000
49	G	H	0.0000
50	I	H	-0.1505
51	F	H	0.0000
52	Y	H	-0.6331
53	P	H	-0.8886
54	G	H	-1.3415
55	D	H	-2.0732
56	S	H	-1.1610
57	S	H	-1.0997
58	T	H	-1.0413
59	R	H	-1.8716
60	Y	H	-1.1019
61	S	H	-0.8179
62	P	H	-1.1260
63	S	H	-0.8761
64	F	H	0.0000
65	Q	H	-2.0463
66	G	H	-1.5082
67	Q	H	-1.6288
68	V	H	0.0000
69	T	H	-1.0460
70	I	H	0.0000
71	S	H	-0.3714
72	A	H	-0.7905
73	D	H	-1.5967
74	K	H	-1.9959
75	S	H	-1.0735
76	V	H	-0.6917
77	N	H	-1.1581
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.6404
81	L	H	0.0000
82	Q	H	-1.4679
83	W	H	0.0000
84	S	H	-1.3203
85	S	H	-1.6367
86	L	H	0.0000
87	K	H	-2.3498
88	A	H	-1.2039
89	S	H	-0.6744
90	D	H	0.0000
91	T	H	-0.2507
92	A	H	0.0000
93	M	H	0.2495
94	Y	H	0.0000
95	Y	H	0.3669
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	R	H	-1.2241
100	R	H	-2.1635
101	N	H	-1.8037
102	W	H	-0.5131
103	G	H	-1.0199
104	N	H	-1.9140
105	A	H	-1.1658
106	F	H	-0.8337
107	D	H	-1.1760
108	I	H	-0.1880
109	W	H	0.3687
110	G	H	-0.0252
111	Q	H	-0.7650
112	G	H	0.0000
113	T	H	0.0000
114	M	H	0.1588
115	V	H	0.0000
116	T	H	0.0000
117	V	H	0.0000
118	S	H	-0.8016
119	S	H	-1.0170
120	A	H	-0.6435
121	S	H	-0.6059
122	T	H	-0.6709
123	K	H	-1.1400
124	G	H	-1.4020
125	P	H	0.0000
126	S	H	-0.0382
127	V	H	0.0000
128	F	H	0.8605
129	P	H	-0.1418
130	L	H	0.1563
131	A	H	-0.9185
132	P	H	0.0000
133	S	H	-0.7858
134	S	H	-0.3226
141	T	H	-0.2748
142	A	H	-0.2094
143	A	H	0.0596
144	L	H	0.0000
145	G	H	0.0000
146	C	H	0.0000
147	L	H	0.7054
148	V	H	0.0000
149	K	H	-0.2269
150	D	H	-0.3691
151	Y	H	0.0000
152	F	H	0.0000
153	P	H	0.0000
154	E	H	-0.6987
155	P	H	-0.9883
156	V	H	-0.7776
157	T	H	-0.6408
158	V	H	-0.1077
159	S	H	-0.3825
160	W	H	0.0000
161	N	H	-0.7358
162	S	H	-0.6701
163	G	H	-0.5126
164	A	H	-0.2126
165	L	H	-0.0143
166	T	H	-0.2913
167	S	H	-0.3873
168	G	H	-0.5037
169	V	H	-0.0169
170	H	H	-0.4769
171	T	H	0.1567
172	F	H	1.0206
173	P	H	0.6949
174	A	H	1.1746
175	V	H	2.4227
176	L	H	2.0097
177	Q	H	0.6666
178	S	H	0.0910
179	S	H	-0.1908
180	G	H	-0.0067
181	L	H	0.1617
182	Y	H	0.0000
183	S	H	0.0000
184	L	H	0.0000
185	S	H	0.6788
186	S	H	0.0000
187	V	H	0.4730
188	V	H	0.0000
189	T	H	-0.2327
190	V	H	0.0000
191	P	H	-0.4897
192	S	H	-0.4472
193	S	H	-0.5282
194	S	H	-0.6292
195	L	H	-0.7771
196	G	H	-1.0430
197	T	H	-0.7760
198	Q	H	-1.3857
199	T	H	-1.2419
200	Y	H	0.0000
201	I	H	-1.6163
202	C	H	0.0000
203	N	H	-1.6677
204	V	H	0.0000
205	N	H	-2.0238
206	H	H	0.0000
207	K	H	-2.8043
208	P	H	-1.6608
209	S	H	-1.7972
210	N	H	-2.6166
211	T	H	-2.0408
212	K	H	-2.7744
213	V	H	-1.8673
214	D	H	-2.8256
215	K	H	-2.4363
216	R	H	-2.8121
217	V	H	0.0000
218	E	H	-2.9650
219	P	H	-2.0894
220	K	H	-2.3088
221	S	H	-1.3080