Project name: 6ayn:B

Chain sequence(s)	B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASSTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9044
• Maximal score value: 2.4376
• Average score: -0.5085
• Total score value: -111.8616

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.3841
2	V	B	-0.6761
3	Q	B	-1.2940
4	L	B	0.0000
5	K	B	-2.1899
6	Q	B	0.0000
7	S	B	-0.8608
8	G	B	-1.0724
9	P	B	-0.3809
10	G	B	-0.3631
11	L	B	0.0119
12	V	B	0.0000
13	Q	B	-1.2320
14	P	B	-1.4450
15	S	B	-1.6454
16	Q	B	-2.0874
17	S	B	-1.9184
18	L	B	0.0000
19	S	B	-0.8239
20	I	B	0.0000
21	T	B	-0.5394
22	C	B	0.0000
23	T	B	-1.0945
24	V	B	0.0000
25	S	B	-1.1594
26	G	B	-0.9131
27	F	B	-0.4867
28	S	B	-0.8635
29	L	B	0.0000
30	T	B	-0.9006
31	N	B	-0.8696
32	Y	B	0.4235
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3133
40	S	B	-0.9561
41	P	B	-1.1175
42	G	B	-1.6618
43	K	B	-2.0300
44	G	B	-0.6645
45	L	B	0.7233
46	E	B	0.0522
47	W	B	0.4564
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.6128
53	S	B	-0.6732
54	G	B	-1.2291
55	G	B	-1.5220
56	N	B	-1.9422
57	T	B	-1.5092
58	D	B	-1.5021
59	Y	B	-0.7037
60	N	B	-0.6917
61	T	B	-0.5405
62	P	B	-0.4783
63	F	B	0.0000
64	T	B	-0.6320
65	S	B	-0.7132
66	R	B	-1.2936
67	L	B	0.0000
68	S	B	-1.2704
69	I	B	0.0000
70	N	B	-1.7265
71	K	B	-1.3590
72	D	B	-1.6925
73	N	B	-2.1001
74	S	B	-1.6200
75	K	B	-2.3136
76	S	B	-1.5421
77	Q	B	-1.4228
78	V	B	0.0000
79	F	B	-0.2704
80	F	B	0.0000
81	K	B	-1.8906
82	M	B	0.0000
83	N	B	-2.4040
84	S	B	-1.7271
85	L	B	0.0000
86	Q	B	-2.1769
87	S	B	-1.5257
88	N	B	-2.0708
89	D	B	0.0000
90	T	B	-0.6838
91	A	B	0.0000
92	I	B	0.5292
93	Y	B	0.0000
94	Y	B	0.0856
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.5887
100	T	B	1.3105
101	Y	B	1.9304
102	Y	B	1.7613
103	D	B	0.7587
104	Y	B	0.7214
105	E	B	-0.3445
106	F	B	0.4531
107	A	B	0.6828
108	Y	B	0.5961
109	W	B	0.1803
110	G	B	0.0000
111	Q	B	-1.4360
112	G	B	0.0000
113	T	B	0.0000
114	L	B	0.3713
115	V	B	0.0000
116	T	B	-0.2629
117	V	B	0.0000
118	S	B	-0.5911
119	A	B	-0.3435
120	A	B	-0.2857
121	S	B	-0.5631
122	T	B	-0.8952
123	K	B	-1.5432
124	G	B	-1.5628
125	P	B	0.0000
126	S	B	-0.1773
127	V	B	0.0000
128	F	B	1.0732
129	P	B	-0.0675
130	L	B	0.3788
131	A	B	-1.0644
132	P	B	0.0000
133	S	B	-1.4154
134	S	B	-1.1887
135	K	B	-1.9183
136	S	B	-1.0327
137	T	B	-1.0219
138	S	B	-0.9540
139	G	B	-0.8550
140	G	B	-0.9211
141	T	B	-0.6626
142	A	B	0.0000
143	A	B	-0.2118
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.7341
148	V	B	0.0000
149	K	B	-0.2755
150	D	B	-0.5800
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.1125
155	P	B	-0.4700
156	V	B	-0.5003
157	T	B	-0.4844
158	V	B	-0.3489
159	S	B	-0.2700
160	W	B	0.0000
161	N	B	-0.8210
162	S	B	-0.5643
163	G	B	-0.5017
164	A	B	-0.2074
165	L	B	-0.0178
166	T	B	-0.2721
167	S	B	-0.3624
168	G	B	-0.4609
169	V	B	0.0327
170	H	B	-0.3867
171	T	B	0.1937
172	F	B	1.0097
173	P	B	0.7503
174	A	B	1.2927
175	V	B	2.4376
176	L	B	2.1512
177	Q	B	0.6906
178	S	B	0.0903
179	S	B	-0.2241
180	G	B	0.2198
181	L	B	0.2147
182	Y	B	0.8027
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.6853
186	S	B	0.0000
187	V	B	0.4584
188	V	B	0.0000
189	T	B	-0.2348
190	V	B	0.0000
191	P	B	-0.5582
192	S	B	-0.6119
193	S	B	-0.5881
194	S	B	-0.6144
195	L	B	-0.7780
196	G	B	-0.9257
197	T	B	-0.7054
198	Q	B	-1.1980
199	T	B	-1.2081
200	Y	B	0.0000
201	I	B	-1.3614
202	C	B	0.0000
203	N	B	-1.2513
204	V	B	0.0000
205	N	B	-1.7576
206	H	B	0.0000
207	K	B	-2.2987
208	P	B	-1.4117
209	S	B	-1.7166
210	N	B	-2.3915
211	T	B	-1.9781
212	K	B	-2.4548
213	V	B	-1.4135
214	D	B	-1.9073
215	K	B	-1.8385
216	R	B	-2.5399
217	V	B	0.0000
218	E	B	-2.9044
219	P	B	-1.8605
220	K	B	-2.2437