Project name: 14-8pig

Chain sequence(s)	H: QVQLQESGPGLVKPSETLSLTCTVSGFSPTNFGVHWIRQPPGKGLEWIGVIWAGGSTNYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARDGYNGYYYTMAYWGQGTSVTVSS; L: DIQMTQSPSSLSASVGDRVTITCSASSTVSFMNWYQQKPGKAPKLLIYSTSILASGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQRSSLPLITFGAGTKLEIKRTV
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.18
• Maximal score value: 1.7598
• Average score: -0.2209
• Total score value: -50.8147

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.7386
2	I	L	-0.2756
3	Q	L	-1.1458
4	M	L	0.0000
5	T	L	-0.0709
6	Q	L	0.0000
7	S	L	-0.1949
8	P	L	-0.2007
9	S	L	-0.2798
10	S	L	-0.3527
11	L	L	0.1449
12	S	L	-0.3315
13	A	L	-0.0401
14	S	L	-0.0421
15	V	L	1.0260
16	G	L	-0.4369
17	D	L	-1.3336
18	R	L	-2.0233
19	V	L	0.0000
20	T	L	-0.0572
21	I	L	0.0000
22	T	L	-0.0361
23	C	L	0.0000
24	S	L	-0.3110
25	A	L	-0.0388
26	S	L	-0.1980
27	S	L	-0.1822
28	T	L	-0.0522
29	V	L	0.1716
31	S	L	-0.0920
32	F	L	0.4380
33	M	L	0.0000
34	N	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	-0.1476
38	Q	L	0.0000
39	K	L	-0.5467
40	P	L	-0.4312
41	G	L	-0.8255
42	K	L	-1.7839
43	A	L	-0.3143
44	P	L	0.0000
45	K	L	-1.6704
46	L	L	-0.1600
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	0.1520
50	S	L	0.0692
51	T	L	-0.0532
52	S	L	-0.0766
53	I	L	0.8447
54	L	L	0.6590
55	A	L	0.0000
56	S	L	-0.2981
57	G	L	-0.5052
58	V	L	0.0000
59	P	L	-0.2058
60	S	L	-0.3208
61	R	L	-0.4473
62	F	L	0.0000
63	S	L	-0.1677
64	G	L	-0.1553
65	S	L	-0.2871
66	G	L	-0.5008
67	S	L	-0.3792
68	G	L	-0.5097
69	T	L	-0.4379
70	D	L	-1.8025
71	F	L	0.0000
72	T	L	-0.0375
73	L	L	0.0000
74	T	L	-0.0184
75	I	L	0.0000
76	S	L	-0.3801
77	S	L	-0.1791
78	L	L	0.0000
79	Q	L	-0.5001
80	P	L	-0.6050
81	E	L	-1.8533
82	D	L	0.0000
83	F	L	0.9072
84	A	L	0.0000
85	T	L	-0.1938
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	Q	L	0.0000
90	Q	L	0.0000
91	R	L	0.0000
92	S	L	-0.0803
93	S	L	-0.0736
94	L	L	0.2721
95	P	L	-0.0186
96	L	L	0.2712
97	I	L	0.0000
98	T	L	0.0335
99	F	L	0.2194
100	G	L	0.0000
101	A	L	0.0585
102	G	L	0.0000
103	T	L	0.0000
104	K	L	-1.4179
105	L	L	0.0000
106	E	L	-1.2738
107	I	L	-0.2245
108	K	L	-1.9920
109	R	L	-2.1800
110	T	L	-0.1026
111	V	L	1.7598
112	Q	H	-1.1983
113	V	H	0.0000
114	Q	H	-1.1983
115	L	H	0.0000
116	Q	H	-1.2426
117	E	H	-0.4988
118	S	H	-0.3088
119	G	H	-0.3979
120	P	H	-0.3235
121	G	H	-0.1424
122	L	H	1.3393
123	V	H	0.0000
124	K	H	-1.2404
125	P	H	-0.3612
126	S	H	-0.5267
127	E	H	-1.4806
128	T	H	-0.3297
129	L	H	0.0000
130	S	H	-0.2314
131	L	H	0.0000
132	T	H	-0.0445
133	C	H	0.0000
134	T	H	-0.0979
135	V	H	0.0000
136	S	H	-0.2449
137	G	H	-0.2689
138	F	H	0.2786
139	S	H	-0.1901
140	P	H	-0.3013
141	T	H	-0.3254
142	N	H	-1.2449
143	F	H	-0.0349
144	G	H	0.0000
145	V	H	0.0000
146	H	H	0.0000
147	W	H	0.0000
148	I	H	0.0000
149	R	H	0.0000
150	Q	H	-0.1115
151	P	H	-0.1025
152	P	H	-0.3461
153	G	H	-0.8202
154	K	H	-1.8167
155	G	H	-0.4579
156	L	H	0.0310
157	E	H	-0.4257
158	W	H	0.0000
159	I	H	0.0000
160	G	H	0.0000
161	V	H	0.0000
162	I	H	0.0000
163	W	H	0.3521
164	A	H	0.0248
165	G	H	-0.5152
166	G	H	-0.4372
167	S	H	-0.2736
168	T	H	-0.1564
169	N	H	-0.4289
170	Y	H	0.3262
171	N	H	0.0000
172	P	H	-0.2790
173	S	H	-0.1816
174	L	H	0.0000
175	K	H	-1.7383
176	S	H	-0.5853
177	R	H	-0.4141
178	V	H	0.0000
179	T	H	-0.0529
180	I	H	0.0000
181	S	H	0.0449
182	V	H	0.9281
183	D	H	-0.9009
184	T	H	-0.3058
185	S	H	-0.5317
186	K	H	-1.8162
187	N	H	-0.8501
188	Q	H	-0.7014
189	F	H	0.0000
190	S	H	-0.0764
191	L	H	0.0000
192	K	H	-1.3602
193	L	H	0.0000
194	S	H	-0.1527
195	S	H	-0.2665
196	V	H	0.0000
197	T	H	-0.0391
198	A	H	0.0599
199	A	H	0.0689
200	D	H	0.0000
201	T	H	-0.0169
202	A	H	0.0000
203	V	H	0.2943
204	Y	H	0.0000
205	Y	H	0.0000
206	C	H	0.0000
207	A	H	0.0000
208	R	H	-0.2025
209	D	H	0.0000
210	G	H	0.0000
211	Y	H	1.1392
212	N	H	-1.0674
213	G	H	-0.6206
214	Y	H	0.4481
215	Y	H	0.4984
216	Y	H	0.7881
217	T	H	0.0000
218	M	H	0.0000
219	A	H	0.0632
220	Y	H	0.3028
221	W	H	0.1792
222	G	H	0.0000
223	Q	H	-1.2178
224	G	H	-0.3270
225	T	H	-0.0708
226	S	H	-0.1606
227	V	H	0.0000
228	T	H	0.1130
229	V	H	0.0000
230	S	H	-0.1188
231	S	H	-0.3506