Project name: 5th2:A
Status: done
submitted: 2019-03-20 20:35:47, status changed: 2019-03-20 20:48:09
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSSCRASQSIGTNIHWYQQRTNGSPRRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQWKVDNNALQSGNSQESVTEQDSSKDSTYSLSSSTLTLSKADDYEKHKVYACCEVTTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.744
-
Maximal score value
-
1.8527
-
Average score
-
-0.8121
-
Total score value
-
-172.9879
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.3078 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.9373 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
0.0425 |
|
| 6 |
Q |
A |
0.1980 |
|
| 7 |
S |
A |
0.3302 |
|
| 8 |
P |
A |
0.8324 |
|
| 9 |
V |
A |
1.8527 |
|
| 10 |
I |
A |
1.2464 |
|
| 11 |
L |
A |
0.4572 |
|
| 12 |
S |
A |
-0.3835 |
|
| 13 |
V |
A |
-1.1484 |
|
| 14 |
S |
A |
-1.8286 |
|
| 15 |
P |
A |
-2.0198 |
|
| 16 |
G |
A |
-2.1095 |
|
| 17 |
E |
A |
-2.9511 |
|
| 18 |
R |
A |
-3.0462 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.8894 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.5950 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-1.6681 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-0.8136 |
|
| 27 |
Q |
A |
-1.2938 |
|
| 28 |
S |
A |
-1.4506 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.1234 |
|
| 31 |
T |
A |
-0.8081 |
|
| 32 |
N |
A |
-1.0264 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0295 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.4456 |
|
| 39 |
R |
A |
-2.0748 |
|
| 40 |
T |
A |
-1.8096 |
|
| 41 |
N |
A |
-1.7504 |
|
| 42 |
G |
A |
-1.5107 |
|
| 43 |
S |
A |
-1.0625 |
|
| 44 |
P |
A |
-0.9920 |
|
| 45 |
R |
A |
-0.8029 |
|
| 46 |
L |
A |
-0.0910 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.7479 |
|
| 50 |
Y |
A |
-0.2101 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.0978 |
|
| 53 |
E |
A |
-1.8765 |
|
| 54 |
S |
A |
-1.0688 |
|
| 55 |
I |
A |
-0.4503 |
|
| 56 |
S |
A |
-0.2395 |
|
| 57 |
G |
A |
-0.3927 |
|
| 58 |
I |
A |
-0.1474 |
|
| 59 |
P |
A |
-0.3016 |
|
| 60 |
S |
A |
-0.5198 |
|
| 61 |
R |
A |
-1.0162 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.8168 |
|
| 64 |
G |
A |
-0.6619 |
|
| 65 |
S |
A |
-0.7981 |
|
| 66 |
G |
A |
-1.0436 |
|
| 67 |
S |
A |
-0.9633 |
|
| 68 |
G |
A |
-1.3024 |
|
| 69 |
T |
A |
-1.7776 |
|
| 70 |
D |
A |
-2.5310 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.8166 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.8220 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.1665 |
|
| 77 |
S |
A |
-2.1969 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.3872 |
|
| 80 |
S |
A |
-2.4096 |
|
| 81 |
E |
A |
-2.4500 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-1.6874 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.8439 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1599 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.3414 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.2845 |
|
| 92 |
N |
A |
-1.7989 |
|
| 93 |
N |
A |
-1.1752 |
|
| 94 |
W |
A |
0.0873 |
|
| 95 |
P |
A |
-0.1200 |
|
| 96 |
T |
A |
-0.4003 |
|
| 97 |
T |
A |
0.3393 |
|
| 98 |
F |
A |
1.4796 |
|
| 99 |
G |
A |
0.7913 |
|
| 100 |
A |
A |
0.6016 |
|
| 101 |
G |
A |
0.3141 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.4498 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.2807 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.8934 |
|
| 108 |
R |
A |
-1.2161 |
|
| 109 |
T |
A |
-0.1831 |
|
| 110 |
V |
A |
0.1845 |
|
| 111 |
A |
A |
-0.2216 |
|
| 112 |
A |
A |
-0.2685 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1138 |
|
| 115 |
V |
A |
0.3841 |
|
| 116 |
F |
A |
1.3132 |
|
| 117 |
I |
A |
1.2631 |
|
| 118 |
F |
A |
1.4203 |
|
| 119 |
P |
A |
-0.0232 |
|
| 120 |
P |
A |
-0.7630 |
|
| 121 |
S |
A |
-1.7950 |
|
| 122 |
D |
A |
-3.1950 |
|
| 123 |
E |
A |
-3.3174 |
|
| 124 |
Q |
A |
-2.3996 |
|
| 125 |
L |
A |
-2.5079 |
|
| 126 |
K |
A |
-2.8901 |
|
| 127 |
S |
A |
-1.8179 |
|
| 128 |
G |
A |
-1.0894 |
|
| 129 |
T |
A |
-0.9224 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0054 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7262 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5496 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.7306 |
|
| 138 |
N |
A |
-1.4077 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.8740 |
|
| 142 |
R |
A |
-3.1838 |
|
| 143 |
E |
A |
-3.2411 |
|
| 144 |
A |
A |
-2.3883 |
|
| 145 |
K |
A |
-2.4940 |
|
| 146 |
V |
A |
-1.1656 |
|
| 147 |
Q |
A |
-0.7778 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.7436 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.9598 |
|
| 152 |
N |
A |
-1.6233 |
|
| 153 |
A |
A |
-0.3868 |
|
| 154 |
L |
A |
0.4541 |
|
| 155 |
Q |
A |
-0.5161 |
|
| 156 |
S |
A |
-0.7520 |
|
| 157 |
G |
A |
-1.4694 |
|
| 158 |
N |
A |
-1.9446 |
|
| 159 |
S |
A |
-1.8626 |
|
| 160 |
Q |
A |
-2.3429 |
|
| 161 |
E |
A |
-2.0255 |
|
| 162 |
S |
A |
-1.1946 |
|
| 163 |
V |
A |
-0.9784 |
|
| 164 |
T |
A |
-1.3379 |
|
| 165 |
E |
A |
-2.3841 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.3732 |
|
| 168 |
S |
A |
-2.4834 |
|
| 169 |
K |
A |
-2.7200 |
|
| 170 |
D |
A |
-2.0274 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.1377 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.3888 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.7157 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.8584 |
|
| 181 |
L |
A |
0.0000 |
|
| 182 |
S |
A |
-1.1086 |
|
| 183 |
K |
A |
-2.0845 |
|
| 184 |
A |
A |
-1.9221 |
|
| 185 |
D |
A |
-2.6117 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.7392 |
|
| 188 |
K |
A |
-3.7440 |
|
| 189 |
H |
A |
-3.2533 |
|
| 190 |
K |
A |
-3.1757 |
|
| 191 |
V |
A |
-1.4928 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.9289 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2045 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.8042 |
|
| 200 |
G |
A |
-0.4873 |
|
| 201 |
L |
A |
-0.2707 |
|
| 202 |
S |
A |
-0.4729 |
|
| 203 |
S |
A |
-0.4259 |
|
| 204 |
P |
A |
-0.5350 |
|
| 205 |
V |
A |
-0.0147 |
|
| 206 |
T |
A |
-0.3920 |
|
| 207 |
K |
A |
-0.3404 |
|
| 208 |
S |
A |
-0.3698 |
|
| 209 |
F |
A |
-0.5329 |
|
| 210 |
N |
A |
-1.6064 |
|
| 211 |
R |
A |
-2.2759 |
|
| 212 |
G |
A |
-1.3977 |
|
| 213 |
A |
A |
-0.7169 |
|