Project name: 5hpm:A
Status: done
submitted: 2019-03-20 20:28:52, status changed: 2019-03-20 20:38:44
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8375
-
Maximal score value
-
1.9226
-
Average score
-
-0.834
-
Total score value
-
-177.6457
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.4191 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7266 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.2549 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.1457 |
|
| 8 |
P |
A |
0.8619 |
|
| 9 |
V |
A |
1.9226 |
|
| 10 |
I |
A |
1.4135 |
|
| 11 |
L |
A |
0.6070 |
|
| 12 |
S |
A |
-0.3232 |
|
| 13 |
V |
A |
-1.1533 |
|
| 14 |
S |
A |
-1.8173 |
|
| 15 |
P |
A |
-1.9790 |
|
| 16 |
G |
A |
-2.2296 |
|
| 17 |
E |
A |
-3.0071 |
|
| 18 |
R |
A |
-3.2529 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7882 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.8185 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.6127 |
|
| 25 |
A |
A |
-1.4130 |
|
| 26 |
S |
A |
-1.0887 |
|
| 27 |
Q |
A |
-1.6473 |
|
| 28 |
S |
A |
-1.5882 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0928 |
|
| 31 |
T |
A |
-0.7738 |
|
| 32 |
N |
A |
-1.0025 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0044 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.4676 |
|
| 39 |
R |
A |
-2.1326 |
|
| 40 |
T |
A |
-1.8946 |
|
| 41 |
N |
A |
-1.9657 |
|
| 42 |
G |
A |
-1.5212 |
|
| 43 |
S |
A |
-1.0529 |
|
| 44 |
P |
A |
-0.9458 |
|
| 45 |
R |
A |
-0.6594 |
|
| 46 |
L |
A |
-0.0593 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.7811 |
|
| 50 |
Y |
A |
-0.2023 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1247 |
|
| 53 |
E |
A |
-1.9029 |
|
| 54 |
S |
A |
-1.1127 |
|
| 55 |
I |
A |
-0.5243 |
|
| 56 |
S |
A |
-0.2648 |
|
| 57 |
G |
A |
-0.4142 |
|
| 58 |
I |
A |
-0.1615 |
|
| 59 |
P |
A |
-0.3181 |
|
| 60 |
S |
A |
-0.6047 |
|
| 61 |
R |
A |
-1.1926 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.9743 |
|
| 64 |
G |
A |
-0.6745 |
|
| 65 |
S |
A |
-0.8041 |
|
| 66 |
G |
A |
-1.1239 |
|
| 67 |
S |
A |
-1.1792 |
|
| 68 |
G |
A |
-1.4622 |
|
| 69 |
T |
A |
-2.1006 |
|
| 70 |
D |
A |
-2.8757 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9328 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.9588 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.7487 |
|
| 77 |
S |
A |
-2.4387 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.3989 |
|
| 80 |
S |
A |
-2.2998 |
|
| 81 |
E |
A |
-2.2123 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-1.5977 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.8126 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1974 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.2547 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.4538 |
|
| 92 |
N |
A |
-1.6438 |
|
| 93 |
N |
A |
-1.2144 |
|
| 94 |
W |
A |
0.0248 |
|
| 95 |
P |
A |
-0.3106 |
|
| 96 |
T |
A |
-0.5549 |
|
| 97 |
T |
A |
0.2249 |
|
| 98 |
F |
A |
1.3408 |
|
| 99 |
G |
A |
0.6347 |
|
| 100 |
A |
A |
0.6296 |
|
| 101 |
G |
A |
0.0000 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.2239 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-0.9495 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.7151 |
|
| 108 |
R |
A |
-1.1629 |
|
| 109 |
T |
A |
-0.0815 |
|
| 110 |
V |
A |
0.6799 |
|
| 111 |
A |
A |
0.1307 |
|
| 112 |
A |
A |
-0.1856 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1963 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.3053 |
|
| 117 |
I |
A |
1.3084 |
|
| 118 |
F |
A |
1.5013 |
|
| 119 |
P |
A |
-0.0254 |
|
| 120 |
P |
A |
-0.7536 |
|
| 121 |
S |
A |
-1.8027 |
|
| 122 |
D |
A |
-3.2077 |
|
| 123 |
E |
A |
-3.3819 |
|
| 124 |
Q |
A |
-2.4630 |
|
| 125 |
L |
A |
-2.6071 |
|
| 126 |
K |
A |
-2.9918 |
|
| 127 |
S |
A |
-1.8691 |
|
| 128 |
G |
A |
-1.5277 |
|
| 129 |
T |
A |
-1.0250 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0299 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7407 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5071 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.7304 |
|
| 138 |
N |
A |
-1.3637 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
-1.1655 |
|
| 141 |
P |
A |
-1.7382 |
|
| 142 |
R |
A |
-3.1843 |
|
| 143 |
E |
A |
-3.2009 |
|
| 144 |
A |
A |
-2.2029 |
|
| 145 |
K |
A |
-2.1944 |
|
| 146 |
V |
A |
-1.0188 |
|
| 147 |
Q |
A |
-0.7563 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.6165 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.8431 |
|
| 152 |
N |
A |
-1.3117 |
|
| 153 |
A |
A |
-0.2336 |
|
| 154 |
L |
A |
0.7259 |
|
| 155 |
Q |
A |
-0.1904 |
|
| 156 |
S |
A |
-0.3917 |
|
| 157 |
G |
A |
-0.9971 |
|
| 158 |
N |
A |
-0.9405 |
|
| 159 |
S |
A |
-1.4035 |
|
| 160 |
Q |
A |
-2.2888 |
|
| 161 |
E |
A |
-2.3317 |
|
| 162 |
S |
A |
-1.3584 |
|
| 163 |
V |
A |
-0.8612 |
|
| 164 |
T |
A |
-1.2595 |
|
| 165 |
E |
A |
-2.5066 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.3774 |
|
| 168 |
S |
A |
-2.4478 |
|
| 169 |
K |
A |
-2.6595 |
|
| 170 |
D |
A |
-1.8297 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.0914 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4888 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5762 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5327 |
|
| 181 |
L |
A |
-0.7984 |
|
| 182 |
S |
A |
-1.2485 |
|
| 183 |
K |
A |
-2.4155 |
|
| 184 |
A |
A |
-2.1163 |
|
| 185 |
D |
A |
-2.8276 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.8375 |
|
| 188 |
K |
A |
-3.8299 |
|
| 189 |
H |
A |
-3.1415 |
|
| 190 |
K |
A |
-3.0406 |
|
| 191 |
V |
A |
-1.4162 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.8752 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.1410 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.6949 |
|
| 200 |
G |
A |
-0.3746 |
|
| 201 |
L |
A |
-0.1734 |
|
| 202 |
S |
A |
-0.4340 |
|
| 203 |
S |
A |
-0.4269 |
|
| 204 |
P |
A |
-0.5766 |
|
| 205 |
V |
A |
-0.0333 |
|
| 206 |
T |
A |
-0.3314 |
|
| 207 |
K |
A |
-0.2532 |
|
| 208 |
S |
A |
-0.3167 |
|
| 209 |
F |
A |
-0.5457 |
|
| 210 |
N |
A |
-1.6417 |
|
| 211 |
R |
A |
-2.4463 |
|
| 212 |
G |
A |
-1.2719 |
|
| 213 |
A |
A |
-0.7455 |
|