| Chain sequence(s) |
A: GQLSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIK B: RGEVSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTQNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRK |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 8 | G | A | -1.1706 | |
| 9 | Q | A | -1.6546 | |
| 10 | L | A | -0.3047 | |
| 11 | S | A | -0.0576 | |
| 12 | V | A | 0.0000 | |
| 13 | C | A | 0.0000 | |
| 14 | D | A | -0.2415 | |
| 15 | S | A | -0.1618 | |
| 16 | I | A | -0.0036 | |
| 17 | S | A | -0.7291 | |
| 18 | E | A | -1.4570 | |
| 19 | W | A | -0.2668 | |
| 20 | V | A | -0.3828 | |
| 21 | T | A | -1.4119 | |
| 22 | A | A | 0.0000 | |
| 23 | A | A | -2.1715 | |
| 24 | D | A | -2.4373 | |
| 25 | K | A | -2.1023 | |
| 26 | K | A | -2.5603 | |
| 27 | T | A | -1.0521 | |
| 28 | A | A | -0.4260 | |
| 29 | V | A | 0.2811 | |
| 30 | D | A | -0.1154 | |
| 31 | M | A | 0.3453 | |
| 32 | S | A | -0.0578 | |
| 33 | G | A | -0.4088 | |
| 34 | G | A | -0.2561 | |
| 35 | T | A | 0.0033 | |
| 36 | V | A | 0.0000 | |
| 37 | T | A | -0.6844 | |
| 38 | V | A | 0.0000 | |
| 39 | L | A | -1.2164 | |
| 40 | E | A | -3.1593 | |
| 41 | K | A | -3.1653 | |
| 42 | V | A | 0.0000 | |
| 43 | P | A | -1.5955 | |
| 44 | V | A | -1.0712 | |
| 45 | S | A | -1.2957 | |
| 46 | K | A | -2.0651 | |
| 47 | G | A | -1.7871 | |
| 48 | Q | A | -2.5443 | |
| 49 | L | A | -1.9797 | |
| 50 | K | A | -2.7288 | |
| 51 | Q | A | 0.0000 | |
| 52 | Y | A | -0.4750 | |
| 53 | F | A | 0.0000 | |
| 54 | Y | A | 0.0212 | |
| 55 | E | A | 0.0000 | |
| 56 | T | A | -0.7997 | |
| 57 | K | A | -1.5116 | |
| 58 | C | A | -0.9612 | |
| 59 | N | A | -0.3306 | |
| 60 | P | A | -0.4359 | |
| 61 | M | A | 0.8249 | |
| 62 | G | A | 0.3046 | |
| 63 | Y | A | 0.5292 | |
| 64 | T | A | 0.0000 | |
| 65 | K | A | -2.4717 | |
| 66 | E | A | -2.9422 | |
| 67 | G | A | -2.4305 | |
| 68 | C | A | -1.5476 | |
| 69 | R | A | -0.5566 | |
| 70 | G | A | -1.2356 | |
| 71 | I | A | 0.0000 | |
| 72 | D | A | -2.7211 | |
| 73 | K | A | -3.3487 | |
| 74 | R | A | -3.4570 | |
| 75 | H | A | -2.6352 | |
| 76 | W | A | -2.2572 | |
| 77 | N | A | -2.8277 | |
| 78 | S | A | -2.2452 | |
| 79 | Q | A | -2.5940 | |
| 80 | C | A | -2.0967 | |
| 81 | R | A | -2.2327 | |
| 82 | T | A | -1.2901 | |
| 83 | T | A | -1.1451 | |
| 84 | Q | A | -1.5702 | |
| 85 | S | A | 0.0000 | |
| 86 | Y | A | -0.2637 | |
| 87 | V | A | -0.2514 | |
| 88 | R | A | -0.3845 | |
| 89 | A | A | 0.0000 | |
| 90 | L | A | 0.0000 | |
| 91 | T | A | 0.0000 | |
| 92 | M | A | -0.6770 | |
| 93 | D | A | -1.6159 | |
| 94 | S | A | -1.9271 | |
| 95 | K | A | -3.0132 | |
| 96 | K | A | -3.1047 | |
| 97 | R | A | -2.4079 | |
| 98 | I | A | 0.1892 | |
| 99 | G | A | 0.0314 | |
| 100 | W | A | 0.3477 | |
| 101 | R | A | -0.0348 | |
| 102 | F | A | 0.0000 | |
| 103 | I | A | 0.0000 | |
| 104 | R | A | -1.3305 | |
| 105 | I | A | 0.0000 | |
| 106 | D | A | -1.1017 | |
| 107 | T | A | 0.0000 | |
| 108 | S | A | 0.0000 | |
| 109 | C | A | 0.0000 | |
| 110 | V | A | -0.5324 | |
| 111 | C | A | 0.0000 | |
| 112 | T | A | -1.2993 | |
| 113 | L | A | 0.0000 | |
| 114 | T | A | -1.1658 | |
| 115 | I | A | -0.1248 | |
| 116 | K | A | -1.9407 | |
| 8 | R | B | -2.3993 | |
| 9 | G | B | -1.5812 | |
| 10 | E | B | -2.0298 | |
| 11 | V | B | -0.8963 | |
| 12 | S | B | -0.9977 | |
| 13 | V | B | 0.0000 | |
| 14 | C | B | 0.0000 | |
| 15 | D | B | -3.1506 | |
| 16 | S | B | -3.0916 | |
| 17 | E | B | -3.1425 | |
| 18 | S | B | -1.0475 | |
| 19 | L | B | 0.4208 | |
| 20 | W | B | 0.8884 | |
| 21 | V | B | 0.2339 | |
| 22 | T | B | -0.8988 | |
| 23 | D | B | -2.1016 | |
| 24 | K | B | -1.2582 | |
| 25 | S | B | -0.9419 | |
| 26 | S | B | -0.6629 | |
| 27 | A | B | 0.0000 | |
| 28 | I | B | -0.2537 | |
| 29 | D | B | 0.0000 | |
| 30 | I | B | 0.1759 | |
| 31 | R | B | -1.4758 | |
| 32 | G | B | -1.2690 | |
| 33 | H | B | -1.3345 | |
| 34 | Q | B | -1.5534 | |
| 35 | V | B | 0.0000 | |
| 36 | T | B | -0.8288 | |
| 37 | V | B | 0.0000 | |
| 38 | L | B | -0.4931 | |
| 39 | G | B | -1.8316 | |
| 40 | E | B | -2.2135 | |
| 41 | I | B | 0.0000 | |
| 42 | K | B | -3.0277 | |
| 43 | T | B | -2.1062 | |
| 44 | Q | B | -2.2985 | |
| 45 | N | B | -2.5007 | |
| 46 | S | B | -1.9266 | |
| 47 | P | B | -2.1590 | |
| 48 | V | B | -1.6324 | |
| 49 | K | B | -2.4747 | |
| 50 | Q | B | 0.0000 | |
| 51 | Y | B | -0.4730 | |
| 52 | F | B | 0.0000 | |
| 53 | Y | B | 0.7579 | |
| 54 | E | B | 0.0000 | |
| 55 | T | B | -1.4945 | |
| 56 | R | B | -3.3333 | |
| 57 | C | B | -3.5490 | |
| 58 | K | B | -4.2964 | |
| 59 | E | B | -4.2422 | |
| 60 | A | B | -3.1003 | |
| 61 | R | B | -4.1428 | |
| 62 | P | B | -2.7236 | |
| 63 | V | B | -1.6986 | |
| 64 | K | B | -2.9595 | |
| 65 | N | B | -3.0532 | |
| 66 | G | B | 0.0000 | |
| 67 | C | B | 0.0000 | |
| 68 | R | B | -2.0508 | |
| 69 | G | B | -1.1588 | |
| 70 | I | B | 0.0000 | |
| 71 | D | B | -2.4523 | |
| 72 | D | B | -3.0944 | |
| 73 | K | B | -2.9563 | |
| 74 | H | B | -3.1607 | |
| 75 | W | B | -2.9068 | |
| 76 | N | B | -3.0867 | |
| 77 | S | B | 0.0000 | |
| 78 | Q | B | -3.0060 | |
| 79 | C | B | 0.0000 | |
| 80 | K | B | -2.3916 | |
| 81 | T | B | -1.8240 | |
| 82 | S | B | -1.0130 | |
| 83 | Q | B | -1.2014 | |
| 84 | T | B | 0.0000 | |
| 85 | Y | B | 0.2472 | |
| 86 | V | B | 0.0000 | |
| 87 | R | B | 0.0080 | |
| 88 | A | B | 0.0000 | |
| 89 | L | B | 0.3766 | |
| 90 | T | B | 0.0000 | |
| 91 | S | B | 0.0000 | |
| 92 | E | B | -1.3887 | |
| 93 | N | B | -2.2501 | |
| 94 | N | B | -2.1575 | |
| 95 | K | B | -1.5124 | |
| 96 | L | B | 1.0371 | |
| 97 | V | B | 1.6063 | |
| 98 | G | B | 1.0503 | |
| 99 | W | B | 0.6949 | |
| 100 | R | B | 0.1519 | |
| 101 | W | B | 0.2112 | |
| 102 | I | B | 0.0000 | |
| 103 | R | B | -0.5593 | |
| 104 | I | B | 0.0000 | |
| 105 | D | B | 0.0000 | |
| 106 | T | B | 0.0000 | |
| 107 | S | B | 0.0000 | |
| 108 | C | B | 0.0000 | |
| 109 | V | B | -0.6493 | |
| 110 | C | B | 0.0000 | |
| 111 | A | B | -0.9535 | |
| 112 | L | B | 0.0000 | |
| 113 | S | B | -2.3181 | |
| 114 | R | B | -3.3849 | |
| 116 | K | B | -3.3177 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine