Project name: 5njd:N
Status: done
submitted: 2019-03-20 16:00:54, status changed: 2019-03-20 17:30:30
Settings
|
Chain sequence(s)
|
N: QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAFIRYDGSNKYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCKTHGSHDNWGQGTMVTVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.7345
-
Maximal score value
-
2.5593
-
Average score
-
-0.5576
-
Total score value
-
-115.4287
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
N |
-1.1298 |
|
| 2 |
V |
N |
-0.4914 |
|
| 3 |
Q |
N |
-1.1254 |
|
| 4 |
L |
N |
0.0000 |
|
| 5 |
V |
N |
0.3315 |
|
| 6 |
E |
N |
0.0000 |
|
| 7 |
S |
N |
-0.5359 |
|
| 8 |
G |
N |
-0.9873 |
|
| 9 |
G |
N |
-0.5089 |
|
| 10 |
G |
N |
-0.1917 |
|
| 11 |
V |
N |
0.1582 |
|
| 12 |
V |
N |
-0.7809 |
|
| 13 |
Q |
N |
-1.8762 |
|
| 14 |
P |
N |
-2.0040 |
|
| 15 |
G |
N |
-1.9651 |
|
| 16 |
R |
N |
-2.6423 |
|
| 17 |
S |
N |
-2.0267 |
|
| 18 |
L |
N |
-1.4041 |
|
| 19 |
R |
N |
-2.0859 |
|
| 20 |
L |
N |
0.0000 |
|
| 21 |
S |
N |
-0.4775 |
|
| 22 |
C |
N |
0.0000 |
|
| 23 |
A |
N |
-0.2639 |
|
| 24 |
A |
N |
0.0000 |
|
| 25 |
S |
N |
-0.4884 |
|
| 26 |
G |
N |
-0.5669 |
|
| 27 |
F |
N |
0.1937 |
|
| 28 |
T |
N |
0.1336 |
|
| 29 |
F |
N |
0.0000 |
|
| 30 |
S |
N |
-0.4517 |
|
| 31 |
S |
N |
0.3437 |
|
| 32 |
Y |
N |
0.9035 |
|
| 33 |
G |
N |
-0.0873 |
|
| 34 |
M |
N |
0.0000 |
|
| 35 |
H |
N |
-0.2561 |
|
| 36 |
W |
N |
0.0000 |
|
| 37 |
V |
N |
0.0000 |
|
| 38 |
R |
N |
0.0000 |
|
| 39 |
Q |
N |
-0.5002 |
|
| 40 |
A |
N |
-1.0603 |
|
| 41 |
P |
N |
-1.0825 |
|
| 42 |
G |
N |
-1.4122 |
|
| 43 |
K |
N |
-2.0961 |
|
| 44 |
G |
N |
-0.9953 |
|
| 45 |
L |
N |
0.4682 |
|
| 46 |
E |
N |
-0.3434 |
|
| 47 |
W |
N |
0.3586 |
|
| 48 |
V |
N |
0.0000 |
|
| 49 |
A |
N |
0.0000 |
|
| 50 |
F |
N |
-0.0075 |
|
| 51 |
I |
N |
0.0000 |
|
| 52 |
R |
N |
-1.1899 |
|
| 53 |
Y |
N |
-0.0630 |
|
| 54 |
D |
N |
-1.6233 |
|
| 55 |
G |
N |
-1.5879 |
|
| 56 |
S |
N |
-1.5202 |
|
| 57 |
N |
N |
-1.7092 |
|
| 58 |
K |
N |
-1.1656 |
|
| 59 |
Y |
N |
0.0138 |
|
| 60 |
Y |
N |
-0.3944 |
|
| 61 |
A |
N |
-1.1321 |
|
| 62 |
D |
N |
-2.4576 |
|
| 63 |
S |
N |
-1.8114 |
|
| 64 |
V |
N |
0.0000 |
|
| 65 |
K |
N |
-2.5571 |
|
| 66 |
G |
N |
-1.8212 |
|
| 67 |
R |
N |
-1.7404 |
|
| 68 |
F |
N |
0.0000 |
|
| 69 |
T |
N |
-0.7712 |
|
| 70 |
I |
N |
0.0000 |
|
| 71 |
S |
N |
-0.4901 |
|
| 72 |
R |
N |
-1.0473 |
|
| 73 |
D |
N |
-1.6319 |
|
| 74 |
N |
N |
-1.7506 |
|
| 75 |
S |
N |
-1.6035 |
|
| 76 |
K |
N |
-2.3678 |
|
| 77 |
N |
N |
-1.7214 |
|
| 78 |
T |
N |
-0.9549 |
|
| 79 |
L |
N |
0.0000 |
|
| 80 |
Y |
N |
-0.4412 |
|
| 81 |
L |
N |
0.0000 |
|
| 82 |
Q |
N |
-1.1390 |
|
| 83 |
M |
N |
0.0000 |
|
| 84 |
N |
N |
-1.8505 |
|
| 85 |
S |
N |
-1.7295 |
|
| 86 |
L |
N |
0.0000 |
|
| 87 |
R |
N |
-2.4610 |
|
| 88 |
A |
N |
-1.7037 |
|
| 89 |
E |
N |
-2.2326 |
|
| 90 |
D |
N |
0.0000 |
|
| 91 |
T |
N |
-0.7255 |
|
| 92 |
A |
N |
0.0000 |
|
| 93 |
V |
N |
0.3144 |
|
| 94 |
Y |
N |
0.0000 |
|
| 95 |
Y |
N |
0.2750 |
|
| 96 |
C |
N |
0.0000 |
|
| 97 |
K |
N |
-0.7087 |
|
| 98 |
T |
N |
-0.9673 |
|
| 99 |
H |
N |
-1.3451 |
|
| 100 |
G |
N |
-1.3882 |
|
| 101 |
S |
N |
-1.3372 |
|
| 102 |
H |
N |
-1.7681 |
|
| 103 |
D |
N |
-1.6673 |
|
| 104 |
N |
N |
-1.3129 |
|
| 105 |
W |
N |
-0.3337 |
|
| 106 |
G |
N |
-0.4779 |
|
| 107 |
Q |
N |
-0.9591 |
|
| 108 |
G |
N |
0.0000 |
|
| 109 |
T |
N |
-0.0745 |
|
| 110 |
M |
N |
0.0351 |
|
| 111 |
V |
N |
0.0000 |
|
| 112 |
T |
N |
-0.3545 |
|
| 113 |
V |
N |
0.0000 |
|
| 114 |
S |
N |
-0.8491 |
|
| 115 |
S |
N |
-0.5981 |
|
| 116 |
A |
N |
-0.4037 |
|
| 117 |
S |
N |
-0.5292 |
|
| 118 |
T |
N |
-0.5835 |
|
| 119 |
K |
N |
-1.0841 |
|
| 120 |
G |
N |
-1.4134 |
|
| 121 |
P |
N |
-0.5220 |
|
| 122 |
S |
N |
-0.0535 |
|
| 123 |
V |
N |
0.5230 |
|
| 124 |
F |
N |
1.7189 |
|
| 125 |
P |
N |
0.4595 |
|
| 126 |
L |
N |
0.4577 |
|
| 127 |
A |
N |
-0.3568 |
|
| 128 |
P |
N |
-0.3121 |
|
| 129 |
S |
N |
-0.1909 |
|
| 137 |
T |
N |
-0.2286 |
|
| 138 |
A |
N |
-0.1576 |
|
| 139 |
A |
N |
0.0891 |
|
| 140 |
L |
N |
0.0000 |
|
| 141 |
G |
N |
0.0000 |
|
| 142 |
C |
N |
0.0000 |
|
| 143 |
L |
N |
0.9236 |
|
| 144 |
V |
N |
0.0000 |
|
| 145 |
K |
N |
-0.2898 |
|
| 146 |
D |
N |
-0.4753 |
|
| 147 |
Y |
N |
0.0000 |
|
| 148 |
F |
N |
-0.1889 |
|
| 149 |
P |
N |
0.0000 |
|
| 150 |
E |
N |
-0.6188 |
|
| 151 |
P |
N |
-0.7297 |
|
| 152 |
V |
N |
-0.4270 |
|
| 153 |
T |
N |
-0.5545 |
|
| 154 |
V |
N |
-0.3527 |
|
| 155 |
S |
N |
-0.4007 |
|
| 156 |
W |
N |
0.0000 |
|
| 157 |
N |
N |
-0.7330 |
|
| 158 |
S |
N |
-0.6586 |
|
| 159 |
G |
N |
-0.5830 |
|
| 160 |
A |
N |
-0.2558 |
|
| 161 |
L |
N |
-0.0246 |
|
| 162 |
T |
N |
-0.2688 |
|
| 163 |
S |
N |
-0.3279 |
|
| 164 |
G |
N |
-0.3593 |
|
| 165 |
V |
N |
-0.0608 |
|
| 166 |
H |
N |
-0.4914 |
|
| 167 |
T |
N |
0.2892 |
|
| 168 |
F |
N |
1.3439 |
|
| 169 |
P |
N |
0.9679 |
|
| 170 |
A |
N |
1.4243 |
|
| 171 |
V |
N |
2.5593 |
|
| 172 |
L |
N |
2.3266 |
|
| 173 |
Q |
N |
0.8421 |
|
| 174 |
S |
N |
0.1823 |
|
| 175 |
S |
N |
-0.1557 |
|
| 176 |
G |
N |
0.3672 |
|
| 177 |
L |
N |
0.5056 |
|
| 178 |
Y |
N |
0.8867 |
|
| 179 |
S |
N |
0.0000 |
|
| 180 |
L |
N |
0.9959 |
|
| 181 |
S |
N |
0.8801 |
|
| 182 |
S |
N |
0.0000 |
|
| 183 |
V |
N |
0.4148 |
|
| 184 |
V |
N |
0.0000 |
|
| 185 |
T |
N |
-0.2555 |
|
| 186 |
V |
N |
0.0000 |
|
| 187 |
P |
N |
-0.3306 |
|
| 188 |
S |
N |
-0.3601 |
|
| 189 |
S |
N |
-0.4155 |
|
| 190 |
S |
N |
-0.3854 |
|
| 191 |
L |
N |
-0.3190 |
|
| 192 |
G |
N |
-0.7576 |
|
| 193 |
T |
N |
-0.5861 |
|
| 194 |
Q |
N |
-1.0881 |
|
| 195 |
T |
N |
-1.0210 |
|
| 196 |
Y |
N |
0.0000 |
|
| 197 |
I |
N |
-1.2608 |
|
| 198 |
C |
N |
0.0000 |
|
| 199 |
N |
N |
-1.4620 |
|
| 200 |
V |
N |
0.0000 |
|
| 201 |
N |
N |
-1.9711 |
|
| 202 |
H |
N |
0.0000 |
|
| 203 |
K |
N |
-2.7345 |
|
| 204 |
P |
N |
-1.4997 |
|
| 205 |
S |
N |
-1.7161 |
|
| 206 |
N |
N |
-2.5793 |
|
| 207 |
T |
N |
-2.1224 |
|
| 208 |
K |
N |
-2.6828 |
|
| 209 |
V |
N |
-1.5668 |
|
| 210 |
D |
N |
-2.3269 |
|
| 211 |
K |
N |
-1.8899 |
|
| 212 |
K |
N |
-2.3799 |
|
| 213 |
V |
N |
0.0000 |
|
| 214 |
E |
N |
-2.2313 |
|