Project name: 5vzx:E
Status: done
submitted: 2019-03-20 20:04:05, status changed: 2019-03-20 20:12:29
Settings
|
Chain sequence(s)
|
E: EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYGMSWVRQAPGKGLELVASINSNGGSTYYPDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCASGDYWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.8242
-
Maximal score value
-
2.3974
-
Average score
-
-0.6209
-
Total score value
-
-132.8721
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
E |
-1.9793 |
|
| 2 |
V |
E |
-1.1275 |
|
| 3 |
Q |
E |
-1.2078 |
|
| 4 |
L |
E |
0.0000 |
|
| 5 |
V |
E |
0.4013 |
|
| 6 |
E |
E |
0.0000 |
|
| 7 |
S |
E |
-0.5353 |
|
| 8 |
G |
E |
-0.9606 |
|
| 9 |
G |
E |
-0.6118 |
|
| 10 |
G |
E |
-0.5878 |
|
| 11 |
L |
E |
-0.1992 |
|
| 12 |
V |
E |
0.0000 |
|
| 13 |
Q |
E |
-1.6690 |
|
| 14 |
P |
E |
-1.7686 |
|
| 15 |
G |
E |
-1.4422 |
|
| 16 |
G |
E |
-1.1303 |
|
| 17 |
S |
E |
-1.2968 |
|
| 18 |
L |
E |
-1.1517 |
|
| 19 |
R |
E |
-2.0251 |
|
| 20 |
L |
E |
0.0000 |
|
| 21 |
S |
E |
-0.5504 |
|
| 22 |
C |
E |
0.0000 |
|
| 23 |
A |
E |
-0.4387 |
|
| 24 |
A |
E |
0.0000 |
|
| 25 |
S |
E |
-1.0837 |
|
| 26 |
G |
E |
-1.0985 |
|
| 27 |
F |
E |
-0.3617 |
|
| 28 |
T |
E |
-0.0989 |
|
| 29 |
F |
E |
0.0000 |
|
| 30 |
S |
E |
-1.0337 |
|
| 31 |
S |
E |
-0.4527 |
|
| 32 |
Y |
E |
-0.4219 |
|
| 33 |
G |
E |
-0.9978 |
|
| 34 |
M |
E |
0.0000 |
|
| 35 |
S |
E |
0.0520 |
|
| 36 |
W |
E |
0.0000 |
|
| 37 |
V |
E |
0.0000 |
|
| 38 |
R |
E |
0.0000 |
|
| 39 |
Q |
E |
-0.6301 |
|
| 40 |
A |
E |
-1.1429 |
|
| 41 |
P |
E |
-1.1421 |
|
| 42 |
G |
E |
-1.4193 |
|
| 43 |
K |
E |
-2.1530 |
|
| 44 |
G |
E |
-1.0684 |
|
| 45 |
L |
E |
0.4213 |
|
| 46 |
E |
E |
-0.5594 |
|
| 47 |
L |
E |
0.5357 |
|
| 48 |
V |
E |
0.0000 |
|
| 49 |
A |
E |
0.0000 |
|
| 50 |
S |
E |
0.0999 |
|
| 51 |
I |
E |
0.0000 |
|
| 52 |
N |
E |
-1.8333 |
|
| 52A |
S |
E |
-1.5319 |
|
| 53 |
N |
E |
-2.1354 |
|
| 54 |
G |
E |
-1.9740 |
|
| 55 |
G |
E |
-1.4340 |
|
| 56 |
S |
E |
-0.9283 |
|
| 57 |
T |
E |
0.0025 |
|
| 58 |
Y |
E |
0.7346 |
|
| 59 |
Y |
E |
-0.3421 |
|
| 60 |
P |
E |
-1.1914 |
|
| 61 |
D |
E |
-2.4818 |
|
| 62 |
S |
E |
-1.8229 |
|
| 63 |
V |
E |
0.0000 |
|
| 64 |
K |
E |
-2.5069 |
|
| 65 |
G |
E |
-1.8288 |
|
| 66 |
R |
E |
-1.7040 |
|
| 67 |
F |
E |
0.0000 |
|
| 68 |
T |
E |
-0.7553 |
|
| 69 |
I |
E |
0.0000 |
|
| 70 |
S |
E |
-0.5765 |
|
| 71 |
R |
E |
-1.4607 |
|
| 72 |
D |
E |
-1.7248 |
|
| 73 |
N |
E |
-1.6659 |
|
| 74 |
A |
E |
-1.4001 |
|
| 75 |
K |
E |
-2.3379 |
|
| 76 |
N |
E |
-1.8703 |
|
| 77 |
S |
E |
0.0000 |
|
| 78 |
L |
E |
0.0000 |
|
| 79 |
Y |
E |
0.0000 |
|
| 80 |
L |
E |
0.0000 |
|
| 81 |
Q |
E |
-1.2808 |
|
| 82 |
M |
E |
0.0000 |
|
| 82A |
N |
E |
-1.5080 |
|
| 82B |
S |
E |
-1.2849 |
|
| 82C |
L |
E |
0.0000 |
|
| 83 |
R |
E |
-2.5001 |
|
| 84 |
A |
E |
-1.8343 |
|
| 85 |
E |
E |
-2.3060 |
|
| 86 |
D |
E |
0.0000 |
|
| 87 |
T |
E |
-0.8413 |
|
| 88 |
A |
E |
0.0000 |
|
| 89 |
V |
E |
0.1565 |
|
| 90 |
Y |
E |
0.0000 |
|
| 91 |
Y |
E |
0.3133 |
|
| 92 |
C |
E |
0.0000 |
|
| 93 |
A |
E |
0.0000 |
|
| 94 |
S |
E |
-0.4219 |
|
| 95 |
G |
E |
-0.9973 |
|
| 101 |
D |
E |
-1.4547 |
|
| 102 |
Y |
E |
-0.2965 |
|
| 103 |
W |
E |
0.2339 |
|
| 104 |
G |
E |
-0.0149 |
|
| 105 |
Q |
E |
-0.8706 |
|
| 106 |
G |
E |
0.0000 |
|
| 107 |
T |
E |
-0.2124 |
|
| 108 |
T |
E |
-0.2447 |
|
| 109 |
V |
E |
0.0000 |
|
| 110 |
T |
E |
0.0000 |
|
| 111 |
V |
E |
0.0000 |
|
| 112 |
S |
E |
-1.0204 |
|
| 113 |
S |
E |
-0.6327 |
|
| 114 |
A |
E |
-0.4821 |
|
| 115 |
S |
E |
-0.5909 |
|
| 116 |
T |
E |
-0.5936 |
|
| 117 |
K |
E |
-1.1885 |
|
| 118 |
G |
E |
-1.4490 |
|
| 119 |
P |
E |
0.0000 |
|
| 120 |
S |
E |
-0.0575 |
|
| 121 |
V |
E |
0.0000 |
|
| 122 |
F |
E |
1.0848 |
|
| 123 |
P |
E |
0.2095 |
|
| 124 |
L |
E |
0.7232 |
|
| 125 |
A |
E |
-0.6628 |
|
| 126 |
P |
E |
0.0000 |
|
| 127 |
S |
E |
-1.3067 |
|
| 128 |
S |
E |
-1.4566 |
|
| 129 |
K |
E |
-2.0029 |
|
| 130 |
S |
E |
-1.2724 |
|
| 131 |
T |
E |
-1.1866 |
|
| 132 |
S |
E |
-0.9560 |
|
| 133 |
G |
E |
-0.9556 |
|
| 134 |
G |
E |
-0.9818 |
|
| 135 |
T |
E |
-0.7084 |
|
| 136 |
A |
E |
0.0000 |
|
| 137 |
A |
E |
0.0971 |
|
| 138 |
L |
E |
0.0000 |
|
| 139 |
G |
E |
0.0000 |
|
| 140 |
C |
E |
0.0000 |
|
| 141 |
L |
E |
0.8214 |
|
| 142 |
V |
E |
0.0000 |
|
| 143 |
K |
E |
-0.1922 |
|
| 144 |
D |
E |
-0.4087 |
|
| 145 |
Y |
E |
0.0000 |
|
| 146 |
F |
E |
0.0000 |
|
| 147 |
P |
E |
0.0000 |
|
| 148 |
E |
E |
-0.5655 |
|
| 149 |
P |
E |
-0.5838 |
|
| 150 |
V |
E |
-0.5864 |
|
| 151 |
T |
E |
-0.5512 |
|
| 152 |
V |
E |
-0.1261 |
|
| 153 |
S |
E |
-0.3460 |
|
| 154 |
W |
E |
0.0000 |
|
| 155 |
N |
E |
-0.7739 |
|
| 156 |
S |
E |
-0.6347 |
|
| 157 |
G |
E |
-0.5134 |
|
| 158 |
A |
E |
-0.2165 |
|
| 159 |
L |
E |
0.0534 |
|
| 160 |
T |
E |
-0.2196 |
|
| 161 |
S |
E |
-0.2802 |
|
| 162 |
G |
E |
-0.3415 |
|
| 163 |
V |
E |
0.1239 |
|
| 164 |
H |
E |
-0.3000 |
|
| 165 |
T |
E |
0.3048 |
|
| 166 |
F |
E |
1.0884 |
|
| 167 |
P |
E |
0.7480 |
|
| 168 |
A |
E |
1.2650 |
|
| 169 |
V |
E |
2.3974 |
|
| 170 |
L |
E |
1.9936 |
|
| 171 |
Q |
E |
0.5951 |
|
| 172 |
S |
E |
0.0505 |
|
| 173 |
S |
E |
-0.2317 |
|
| 174 |
G |
E |
0.2321 |
|
| 175 |
L |
E |
0.3095 |
|
| 176 |
Y |
E |
0.8292 |
|
| 177 |
S |
E |
0.0000 |
|
| 178 |
L |
E |
0.0000 |
|
| 179 |
S |
E |
0.7345 |
|
| 180 |
S |
E |
0.0000 |
|
| 181 |
V |
E |
0.4914 |
|
| 182 |
V |
E |
0.0000 |
|
| 183 |
T |
E |
-0.2183 |
|
| 184 |
V |
E |
0.0000 |
|
| 185 |
P |
E |
-0.6221 |
|
| 186 |
S |
E |
-0.8767 |
|
| 187 |
S |
E |
-0.5013 |
|
| 188 |
S |
E |
-0.5853 |
|
| 189 |
L |
E |
-0.8165 |
|
| 190 |
G |
E |
-1.0704 |
|
| 191 |
T |
E |
-0.8877 |
|
| 192 |
Q |
E |
-1.3539 |
|
| 193 |
T |
E |
-1.3055 |
|
| 194 |
Y |
E |
0.0000 |
|
| 195 |
I |
E |
-1.3540 |
|
| 196 |
C |
E |
0.0000 |
|
| 197 |
N |
E |
-1.4225 |
|
| 198 |
V |
E |
0.0000 |
|
| 199 |
N |
E |
-1.8805 |
|
| 200 |
H |
E |
0.0000 |
|
| 201 |
K |
E |
-2.7255 |
|
| 202 |
P |
E |
-1.5865 |
|
| 203 |
S |
E |
-1.8593 |
|
| 204 |
N |
E |
-2.6096 |
|
| 205 |
T |
E |
-2.1061 |
|
| 206 |
K |
E |
-2.7160 |
|
| 207 |
V |
E |
-1.6495 |
|
| 208 |
D |
E |
-2.4109 |
|
| 209 |
K |
E |
-2.1794 |
|
| 210 |
K |
E |
-2.5289 |
|
| 211 |
V |
E |
0.0000 |
|
| 212 |
E |
E |
-2.8242 |
|
| 213 |
P |
E |
-1.8744 |
|
| 214 |
K |
E |
-2.4186 |
|
| 215 |
S |
E |
-1.2955 |
|