Project name: 5esq:A
Status: done
submitted: 2019-03-20 20:25:24, status changed: 2019-03-20 20:39:11
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADDYEKHKVYACEVTHQGLSSPVTKSFNRGA
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8236
-
Maximal score value
-
1.9055
-
Average score
-
-0.8543
-
Total score value
-
-181.9695
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.2823 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7523 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.2304 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.0969 |
|
| 8 |
P |
A |
0.8586 |
|
| 9 |
V |
A |
1.9055 |
|
| 10 |
I |
A |
1.3887 |
|
| 11 |
L |
A |
0.5118 |
|
| 12 |
S |
A |
-0.4013 |
|
| 13 |
V |
A |
-1.1172 |
|
| 14 |
S |
A |
-1.7347 |
|
| 15 |
P |
A |
-2.0481 |
|
| 16 |
G |
A |
-2.1822 |
|
| 17 |
E |
A |
-2.8628 |
|
| 18 |
R |
A |
-3.1937 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.8414 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.6803 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.3398 |
|
| 25 |
A |
A |
-1.2642 |
|
| 26 |
S |
A |
-1.0128 |
|
| 27 |
Q |
A |
-1.4832 |
|
| 28 |
S |
A |
-1.4987 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0015 |
|
| 31 |
T |
A |
-0.6826 |
|
| 32 |
N |
A |
-0.9182 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.1703 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.9425 |
|
| 39 |
R |
A |
-2.9846 |
|
| 40 |
T |
A |
-2.2227 |
|
| 41 |
N |
A |
-1.9578 |
|
| 42 |
G |
A |
-1.8009 |
|
| 43 |
S |
A |
-1.2828 |
|
| 44 |
P |
A |
-1.2712 |
|
| 45 |
R |
A |
-1.1805 |
|
| 46 |
L |
A |
-0.3015 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.7987 |
|
| 50 |
Y |
A |
-0.2405 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1567 |
|
| 53 |
E |
A |
-1.9081 |
|
| 54 |
S |
A |
-1.1073 |
|
| 55 |
I |
A |
-0.5059 |
|
| 56 |
S |
A |
-0.2464 |
|
| 57 |
G |
A |
-0.4025 |
|
| 58 |
I |
A |
-0.1889 |
|
| 59 |
P |
A |
-0.2953 |
|
| 60 |
S |
A |
-0.6055 |
|
| 61 |
R |
A |
-1.2514 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.9956 |
|
| 64 |
G |
A |
-0.6952 |
|
| 65 |
S |
A |
-0.7176 |
|
| 66 |
G |
A |
-0.9175 |
|
| 67 |
S |
A |
-0.9631 |
|
| 68 |
G |
A |
-1.2660 |
|
| 69 |
T |
A |
-1.7699 |
|
| 70 |
D |
A |
-2.1438 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.7916 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-1.0123 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.8377 |
|
| 77 |
S |
A |
-2.4929 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.8224 |
|
| 80 |
S |
A |
-2.6398 |
|
| 81 |
E |
A |
-2.8980 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
-2.0249 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-1.1572 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1099 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.1273 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.4072 |
|
| 92 |
N |
A |
-1.5048 |
|
| 93 |
N |
A |
-1.1809 |
|
| 94 |
W |
A |
0.0841 |
|
| 95 |
P |
A |
-0.1259 |
|
| 96 |
T |
A |
-0.4447 |
|
| 97 |
T |
A |
0.3077 |
|
| 98 |
F |
A |
1.4226 |
|
| 99 |
G |
A |
0.6522 |
|
| 100 |
A |
A |
0.5865 |
|
| 101 |
G |
A |
0.3023 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.4612 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-1.0376 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.5548 |
|
| 108 |
R |
A |
-0.9882 |
|
| 109 |
T |
A |
-0.0876 |
|
| 110 |
V |
A |
0.3034 |
|
| 111 |
A |
A |
-0.1680 |
|
| 112 |
A |
A |
-0.2305 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1751 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.1795 |
|
| 117 |
I |
A |
1.1472 |
|
| 118 |
F |
A |
1.3326 |
|
| 119 |
P |
A |
-0.0939 |
|
| 120 |
P |
A |
-0.7781 |
|
| 121 |
S |
A |
-1.8074 |
|
| 122 |
D |
A |
-3.1859 |
|
| 123 |
E |
A |
-3.3649 |
|
| 124 |
Q |
A |
-2.4821 |
|
| 125 |
L |
A |
-2.6016 |
|
| 126 |
K |
A |
-2.9611 |
|
| 127 |
S |
A |
-1.8689 |
|
| 128 |
G |
A |
-1.5638 |
|
| 129 |
T |
A |
-1.0547 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
-0.0090 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.6524 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.6359 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.7006 |
|
| 138 |
N |
A |
-1.3654 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.8205 |
|
| 142 |
R |
A |
-2.9822 |
|
| 143 |
E |
A |
-3.2339 |
|
| 144 |
A |
A |
-2.2664 |
|
| 145 |
K |
A |
-2.1009 |
|
| 146 |
V |
A |
-1.0916 |
|
| 147 |
Q |
A |
-0.7175 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.6590 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.8512 |
|
| 152 |
N |
A |
-1.4905 |
|
| 153 |
A |
A |
-0.2454 |
|
| 154 |
L |
A |
0.7521 |
|
| 155 |
Q |
A |
-0.1693 |
|
| 156 |
S |
A |
-0.5140 |
|
| 157 |
G |
A |
-1.0249 |
|
| 158 |
N |
A |
-1.0134 |
|
| 159 |
S |
A |
-1.4485 |
|
| 160 |
Q |
A |
-2.3366 |
|
| 161 |
E |
A |
-2.3594 |
|
| 162 |
S |
A |
-1.3197 |
|
| 163 |
V |
A |
-0.7912 |
|
| 164 |
T |
A |
-1.2665 |
|
| 165 |
E |
A |
-2.4389 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.4003 |
|
| 168 |
S |
A |
-2.7276 |
|
| 169 |
K |
A |
-2.8224 |
|
| 170 |
D |
A |
-1.9442 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.0817 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4521 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5905 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5718 |
|
| 181 |
L |
A |
-0.8015 |
|
| 182 |
S |
A |
-1.2420 |
|
| 183 |
K |
A |
-2.4388 |
|
| 184 |
A |
A |
-2.1036 |
|
| 185 |
D |
A |
-2.7016 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.8236 |
|
| 188 |
K |
A |
-3.7694 |
|
| 189 |
H |
A |
-3.0956 |
|
| 190 |
K |
A |
-3.1480 |
|
| 191 |
V |
A |
-1.3998 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
-0.8399 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.9908 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.1952 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.7232 |
|
| 200 |
G |
A |
-0.4068 |
|
| 201 |
L |
A |
-0.1931 |
|
| 202 |
S |
A |
-0.4347 |
|
| 203 |
S |
A |
-0.4005 |
|
| 204 |
P |
A |
-0.5811 |
|
| 205 |
V |
A |
-0.0596 |
|
| 206 |
T |
A |
-0.3906 |
|
| 207 |
K |
A |
-0.3585 |
|
| 208 |
S |
A |
-0.3964 |
|
| 209 |
F |
A |
-0.6083 |
|
| 210 |
N |
A |
-1.6747 |
|
| 211 |
R |
A |
-2.3728 |
|
| 212 |
G |
A |
-1.4577 |
|
| 213 |
A |
A |
-0.7923 |
|