Project name: 4hjg:B

Chain sequence(s)	B: EVQLVESGGGLVVQPGGSLRLSSCAASGFNIKDTYIHWVRQSSPGKGLEWVARIYPTNGYTRRYADSVKKGRFTISADTSKNTAYLQMNSLRAEEDTAIYYCSRWGGDGFYAMDYWGQGTLVTVSSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTTVPSSSLGTQTTYICNVNNHKPSNTKVDKKVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8958
• Maximal score value: 2.5012
• Average score: -0.5888
• Total score value: -130.1234

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.0907
2	V	B	-1.3044
3	Q	B	-1.0473
4	L	B	0.0000
5	V	B	0.6402
6	E	B	0.0000
7	S	B	-0.4385
8	G	B	-0.8340
9	G	B	-0.4105
10	G	B	-0.4245
11	L	B	-0.0281
12	V	B	-0.6125
13	Q	B	-1.5634
14	P	B	-1.6765
15	G	B	-1.4127
16	G	B	-1.0879
17	S	B	-1.1153
18	L	B	-1.0646
19	R	B	-1.9561
20	L	B	0.0000
21	S	B	-0.3783
22	C	B	0.0000
23	A	B	-0.1649
24	A	B	0.0000
25	S	B	-1.1427
26	G	B	-1.4126
27	F	B	-1.5581
28	N	B	-2.1184
29	I	B	0.0000
30	K	B	-2.8121
31	D	B	-2.8924
32	T	B	0.0000
33	Y	B	-0.0662
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.5241
40	S	B	-1.1649
41	P	B	-1.0771
42	G	B	-1.5695
43	K	B	-2.1290
44	G	B	-1.0372
45	L	B	0.4527
46	E	B	-0.5863
47	W	B	0.0402
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-1.0710
51	I	B	0.0000
52	Y	B	-0.5378
53	P	B	-1.1895
54	T	B	-1.3475
55	N	B	-1.0910
56	G	B	-0.5595
57	Y	B	0.3519
58	T	B	-0.6893
59	R	B	-2.1971
60	Y	B	-1.9559
61	A	B	-1.8979
62	D	B	-2.6798
63	S	B	-1.6443
64	V	B	0.0000
65	K	B	-2.8958
66	G	B	-1.8083
67	R	B	-1.4456
68	F	B	0.0000
69	T	B	-1.1657
70	I	B	0.0000
71	S	B	-0.1814
72	A	B	-0.7623
73	D	B	-1.3993
74	T	B	-1.7638
75	S	B	-1.5431
76	K	B	-2.1829
77	N	B	-1.7658
78	T	B	-0.9990
79	A	B	0.0000
80	Y	B	-0.4024
81	L	B	0.0000
82	Q	B	-1.1095
83	M	B	0.0000
84	N	B	-1.4664
85	S	B	-1.2917
86	L	B	0.0000
87	R	B	-2.3207
88	A	B	-1.7319
89	E	B	-2.2387
90	D	B	0.0000
91	T	B	-0.7691
92	A	B	0.0000
93	I	B	0.4106
94	Y	B	0.0000
95	Y	B	0.4635
96	C	B	0.0000
97	S	B	0.0000
98	R	B	0.0000
99	W	B	0.6277
100	G	B	0.3955
101	G	B	0.0000
102	D	B	-1.5367
103	G	B	-0.2297
104	F	B	1.7327
105	Y	B	1.8993
106	A	B	1.2470
107	M	B	0.8681
108	D	B	0.1708
109	Y	B	0.1953
110	W	B	0.3620
111	G	B	-0.0500
112	Q	B	-0.7865
113	G	B	0.0000
114	T	B	0.0101
115	L	B	0.0838
116	V	B	0.0000
117	T	B	-0.4306
118	V	B	0.0000
119	S	B	-0.9439
120	S	B	-0.6823
121	A	B	-0.4198
122	S	B	-0.5115
123	T	B	-0.6697
124	K	B	-1.0430
125	G	B	-1.3921
126	P	B	-0.5691
127	S	B	-0.0989
128	V	B	0.0000
129	F	B	0.8187
130	P	B	-0.1283
131	L	B	0.2731
132	A	B	-1.1079
133	P	B	0.0000
134	S	B	-1.3624
135	S	B	-1.1787
136	K	B	-1.9172
137	S	B	-1.0215
138	T	B	-1.0105
139	S	B	-0.9475
140	G	B	-0.8574
141	G	B	-0.9198
142	T	B	-0.6380
143	A	B	0.0000
144	A	B	-0.2188
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.6897
149	V	B	0.0000
150	K	B	-0.2036
151	D	B	-0.3348
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.4578
156	P	B	-0.7264
157	V	B	-0.6768
158	T	B	-0.6024
159	V	B	-0.2507
160	S	B	-0.3790
161	W	B	0.0000
162	N	B	-0.7619
163	S	B	-0.6457
164	G	B	-0.5751
165	A	B	-0.2530
166	L	B	-0.0198
167	T	B	-0.2970
168	S	B	-0.3170
169	G	B	-0.3635
170	V	B	-0.0643
171	H	B	-0.5410
172	T	B	0.1631
173	F	B	0.9436
174	P	B	0.7335
175	A	B	1.2917
176	V	B	2.5012
177	L	B	2.1702
178	Q	B	0.7071
179	S	B	0.0967
180	S	B	-0.2007
181	G	B	0.2606
182	L	B	0.3756
183	Y	B	0.9212
184	S	B	0.0000
185	L	B	0.0000
186	S	B	0.6418
187	S	B	0.0000
188	V	B	0.3355
189	V	B	0.0000
190	T	B	-0.2155
191	V	B	0.0000
192	P	B	-0.6223
193	S	B	-0.5564
194	S	B	-0.5308
195	S	B	-0.5121
196	L	B	-0.6901
197	G	B	-1.0458
198	T	B	-0.6765
199	Q	B	-1.1847
200	T	B	-1.1068
201	Y	B	0.0000
202	I	B	-1.2745
203	C	B	0.0000
204	N	B	-1.4121
205	V	B	0.0000
206	N	B	-2.0282
207	H	B	0.0000
208	K	B	-2.8118
209	P	B	-1.6029
210	S	B	-1.8338
211	N	B	-2.5739
212	T	B	-2.1098
213	K	B	-2.7103
214	V	B	-1.6113
215	D	B	-2.2763
216	K	B	-2.0047
217	K	B	-2.4391
218	V	B	0.0000
219	E	B	-2.8600
220	P	B	-1.9136
221	K	B	-2.2477