Project name: dtave2

Chain sequence(s)	H: LQLQESGPGLVKPSETLSLTCPVSGGSISSDVSYWGWIRQPPGKGLEWIGSIYYSGKTFYNPALKSRLTISVDTSRNQFSLKLKSVTAADTAVYYFARPTGGATRGFDYWGQGTLVTVSS; L: SALTQPAHLSESLLQPITLACTGTSSDVGGYNYVSWYQQHPGKAPKLMIYDVSNRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCSSYTSSSTRVFGTGTKVTVL
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -1.9279
• Maximal score value: 1.5801
• Average score: -0.2009
• Total score value: -46.0144

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	L	H	0.2975
3	Q	H	-1.1078
4	L	H	0.0000
5	Q	H	-0.6087
6	E	H	0.0000
7	S	H	-0.2560
8	G	H	-0.5409
9	P	H	-0.3642
11	G	H	-0.0113
12	L	H	1.5009
13	V	H	0.0000
14	K	H	-1.7672
15	P	H	-0.4574
16	S	H	-0.3951
17	E	H	-0.7875
18	T	H	-0.3606
19	L	H	0.0000
20	S	H	-0.2760
21	L	H	0.0000
22	T	H	-0.0242
23	C	H	0.0000
24	P	H	-0.0881
25	V	H	0.0000
26	S	H	-0.2999
27	G	H	-0.5464
28	G	H	-0.3442
29	S	H	-0.2538
30	I	H	0.0000
31	S	H	-0.0160
34	S	H	-0.4770
35	D	H	-1.4870
36	V	H	1.4425
37	S	H	0.0000
38	Y	H	0.1760
39	W	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	I	H	0.0000
43	R	H	0.0000
44	Q	H	-0.2231
45	P	H	-0.1626
46	P	H	-0.3467
47	G	H	-0.8275
48	K	H	-1.7940
49	G	H	-0.3698
50	L	H	0.0000
51	E	H	-0.4721
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	S	H	0.0000
56	I	H	0.0000
57	Y	H	0.2471
58	Y	H	0.5409
59	S	H	-0.1557
63	G	H	-0.5916
64	K	H	-1.7310
65	T	H	-0.2095
66	F	H	0.6362
67	Y	H	0.2241
68	N	H	-0.1959
69	P	H	-0.2762
70	A	H	0.0124
71	L	H	0.0000
72	K	H	-1.7390
74	S	H	-0.6104
75	R	H	-0.5121
76	L	H	0.0000
77	T	H	-0.0543
78	I	H	0.0000
79	S	H	-0.0551
80	V	H	0.3785
81	D	H	-0.4571
82	T	H	-0.2289
83	S	H	-0.5603
84	R	H	-1.9279
85	N	H	-0.6260
86	Q	H	-0.3001
87	F	H	0.0000
88	S	H	-0.0543
89	L	H	0.0000
90	K	H	-1.2588
91	L	H	0.0000
92	K	H	-1.5103
93	S	H	-0.5879
94	V	H	0.0000
95	T	H	-0.0462
96	A	H	0.0586
97	A	H	0.0690
98	D	H	0.0000
99	T	H	-0.0173
100	A	H	0.0000
101	V	H	0.3885
102	Y	H	0.0000
103	Y	H	0.0000
104	F	H	0.0000
105	A	H	0.0000
106	R	H	-0.2100
107	P	H	0.0000
108	T	H	-0.1567
109	G	H	-0.5202
110	G	H	-0.5431
111	A	H	-0.0843
112	T	H	-0.0861
113	R	H	-0.3573
114	G	H	-0.1073
115	F	H	0.0000
116	D	H	-0.3677
117	Y	H	0.4329
118	W	H	0.0000
119	G	H	0.0000
120	Q	H	-0.5251
121	G	H	-0.1563
122	T	H	0.1337
123	L	H	0.7613
124	V	H	0.0000
125	T	H	0.1414
126	V	H	0.0000
127	S	H	-0.3760
128	S	H	-0.4950
2	S	L	-0.2060
3	A	L	-0.0015
4	L	L	0.0000
5	T	L	-0.0737
6	Q	L	0.0000
7	P	L	-0.0830
8	A	L	-0.1420
9	H	L	-1.0577
11	L	L	0.1784
12	S	L	-0.1552
13	E	L	-0.5490
14	S	L	0.1683
15	L	L	1.2033
16	L	L	1.5801
17	Q	L	-0.4387
18	P	L	-0.3680
19	I	L	0.0000
20	T	L	-0.0444
21	L	L	0.0000
22	A	L	0.0167
23	C	L	0.0000
24	T	L	-0.0465
25	G	L	-0.0718
26	T	L	-0.1189
27	S	L	-0.3441
28	S	L	-0.2512
29	D	L	0.0000
30	V	L	0.0000
31	G	L	-0.4662
35	G	L	-0.2708
36	Y	L	0.3804
37	N	L	-1.0461
38	Y	L	0.2390
39	V	L	0.0000
40	S	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	-0.1393
44	Q	L	0.0000
45	H	L	-0.2955
46	P	L	-0.3840
47	G	L	-0.8175
48	K	L	-1.7796
49	A	L	-0.3785
50	P	L	0.0000
51	K	L	-1.7000
52	L	L	0.0000
53	M	L	0.0000
54	I	L	0.0000
55	Y	L	0.2866
56	D	L	-0.4651
57	V	L	0.0000
65	S	L	-0.2967
66	N	L	-1.0689
67	R	L	-1.0388
68	P	L	-0.2379
69	S	L	-0.3055
70	G	L	-0.4723
71	V	L	0.0812
72	S	L	-0.2893
74	N	L	-1.4430
75	R	L	-1.0882
76	F	L	0.0000
77	S	L	-0.0796
78	G	L	-0.1216
79	S	L	-0.2822
80	K	L	-0.4028
83	S	L	-0.3576
84	G	L	-0.6425
85	N	L	-0.8757
86	T	L	-0.1553
87	A	L	0.0000
88	S	L	-0.0394
89	L	L	0.0000
90	T	L	-0.0270
91	I	L	0.0000
92	S	L	-0.2296
93	G	L	0.0707
94	L	L	0.0000
95	Q	L	-0.5496
96	A	L	-0.3750
97	E	L	-1.8092
98	D	L	0.0000
99	E	L	-1.1152
100	A	L	0.0000
101	D	L	-0.5550
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	S	L	0.0000
106	S	L	0.0000
107	Y	L	0.0000
108	T	L	-0.0269
109	S	L	-0.1288
113	S	L	-0.2291
114	S	L	0.0000
115	T	L	-0.0083
116	R	L	0.0000
117	V	L	0.3079
118	F	L	0.0000
119	G	L	0.0000
120	T	L	-0.0656
121	G	L	-0.0716
122	T	L	0.0000
123	K	L	-1.5640
124	V	L	0.0000
125	T	L	-0.0150
126	V	L	0.4748
127	L	L	1.5743