Project name: ACR243561Lentinula_edodes

Chain sequence(s)	A: SIGPTADMYIVNEDISPDGFNRSAVLAGDAEDSVSFPGPLVVGTKGSTFKINVIDDLTDTTMLRSTSIHWHGMFQNGTAWADGTSGVTQCPISPGNSFLYQFTATDQAGTFWYHSHRSTQYCDGLRGALVIYDDDDPYLSEYSVDNETTVIALADWYHTPAPSAGTVPTSDATLINGLGRYASGPASDLAVIQVEQGVKYRFRLVSISCDPNFTFSIDNHTMTIIEVDGNNVEPVVADSIQIFASQRYSFILNANQTISNYWIRAQPNVGTTGYDGGINSAILRYLSASEEEPTTPEVTTTNLLAETSLIPLENPGAPGGSDPADVAYNLAITFNGSAFAINDATYIEEVSLPVLLQILSGTTSAQDLLPDGSVYTLPRNSTIELSLPGGAVGSPHPFHLHGHAFDVIRSAGSSTYNYVNPPRRDTVSLGETGDNVTIRFSTYNPGPWILHCHIDWHLDIGLAVVMAEAPSDIENLAVTDSWSDLCSTYADQDS
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.3223
• Maximal score value: 1.8677
• Average score: -0.1901
• Total score value: -93.8927

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
25	S	A	-0.1751
26	I	A	0.1428
27	G	A	-0.1612
28	P	A	-0.1269
29	T	A	-0.1840
30	A	A	-0.1310
31	D	A	-0.7219
32	M	A	0.0000
33	Y	A	0.3343
34	I	A	0.0000
35	V	A	0.2187
36	N	A	-0.5039
37	E	A	-1.6885
38	D	A	-1.9847
39	I	A	-0.0606
40	S	A	-0.2078
41	P	A	0.0000
42	D	A	0.0000
43	G	A	-0.2406
44	F	A	0.3233
45	N	A	-1.1730
46	R	A	0.0000
47	S	A	-0.3260
48	A	A	0.0000
49	V	A	0.0000
50	L	A	0.0000
51	A	A	0.0000
52	G	A	0.0000
53	D	A	-0.5698
54	A	A	-0.4221
55	E	A	-2.1411
56	D	A	-2.1576
57	S	A	-0.4888
58	V	A	0.2441
59	S	A	-0.0039
60	F	A	0.1786
61	P	A	0.0214
62	G	A	0.0000
63	P	A	-0.0280
64	L	A	0.0000
65	V	A	0.0000
66	V	A	0.2566
67	G	A	0.0000
68	T	A	-0.2065
69	K	A	-1.0946
70	G	A	-0.6140
71	S	A	-0.1138
72	T	A	-0.0743
73	F	A	0.0000
74	K	A	-0.7412
75	I	A	0.0000
76	N	A	-0.2945
77	V	A	0.0000
78	I	A	0.3261
79	D	A	0.0000
80	D	A	-1.7894
81	L	A	0.0000
82	T	A	-0.1448
83	D	A	-0.4239
84	T	A	-0.1100
85	T	A	-0.0805
86	M	A	0.0000
87	L	A	0.1621
88	R	A	-0.3377
89	S	A	0.0000
90	T	A	0.0000
91	S	A	0.0000
92	I	A	0.0000
93	H	A	0.0000
94	W	A	0.0000
95	H	A	0.0000
96	G	A	-0.0504
97	M	A	0.0000
98	F	A	0.3167
99	Q	A	0.0000
100	N	A	-1.2918
101	G	A	-0.2969
102	T	A	-0.0294
103	A	A	0.0000
104	W	A	0.0000
105	A	A	0.0000
106	D	A	0.0000
107	G	A	0.0000
108	T	A	0.0000
109	S	A	-0.0401
110	G	A	-0.0553
111	V	A	0.0000
112	T	A	0.0000
113	Q	A	0.0000
114	C	A	0.0786
115	P	A	-0.0212
116	I	A	0.0000
117	S	A	-0.1076
118	P	A	-0.1424
119	G	A	-0.6965
120	N	A	-1.3455
121	S	A	-0.3920
122	F	A	0.0000
123	L	A	0.3740
124	Y	A	0.0000
125	Q	A	-0.5208
126	F	A	0.0000
127	T	A	-0.0660
128	A	A	0.0000
129	T	A	-0.4657
130	D	A	-1.8250
131	Q	A	-0.4471
132	A	A	-0.0138
133	G	A	0.0000
134	T	A	0.0000
135	F	A	0.0000
136	W	A	0.0000
137	Y	A	0.0000
138	H	A	0.0000
139	S	A	0.0000
140	H	A	0.0000
141	R	A	-0.3060
142	S	A	-0.1725
143	T	A	0.0000
144	Q	A	0.0000
145	Y	A	0.0000
146	C	A	0.0000
147	D	A	0.0000
148	G	A	0.0000
149	L	A	0.0000
150	R	A	0.0000
151	G	A	0.0000
152	A	A	0.0000
153	L	A	0.0000
154	V	A	0.0000
155	I	A	0.0000
156	Y	A	0.2262
157	D	A	-0.5454
158	D	A	-2.1566
159	D	A	-2.1429
160	D	A	-0.5676
161	P	A	-0.2870
162	Y	A	0.0000
163	L	A	0.9979
164	S	A	-0.3516
165	E	A	-1.8487
166	Y	A	0.0000
167	S	A	-0.1393
168	V	A	0.3195
169	D	A	-0.4240
170	N	A	-1.6127
171	E	A	-1.8673
172	T	A	-0.3393
173	T	A	0.0000
174	V	A	0.0000
175	I	A	0.0000
176	A	A	0.0000
177	L	A	0.0000
178	A	A	0.0000
179	D	A	0.0000
180	W	A	0.0000
181	Y	A	0.0000
182	H	A	-0.2011
183	T	A	-0.0902
184	P	A	-0.0633
185	A	A	0.0000
186	P	A	-0.2928
187	S	A	-0.2539
188	A	A	-0.1009
189	G	A	-0.4748
190	T	A	0.1651
191	V	A	1.7536
192	P	A	0.2723
193	T	A	-0.0813
194	S	A	-0.1191
195	D	A	-0.4681
196	A	A	0.0000
197	T	A	0.0000
198	L	A	0.0000
199	I	A	0.0000
200	N	A	-0.5560
201	G	A	0.0000
202	L	A	0.3277
203	G	A	0.0000
204	R	A	-0.1834
205	Y	A	0.1960
206	A	A	0.0590
207	S	A	-0.2249
208	G	A	-0.1798
209	P	A	-0.2665
210	A	A	0.0074
211	S	A	-0.3388
212	D	A	-1.7937
213	L	A	0.0000
214	A	A	0.0000
215	V	A	0.4575
216	I	A	0.0000
217	Q	A	-0.9283
218	V	A	0.0000
219	E	A	-1.1471
220	Q	A	-1.4510
221	G	A	-0.6203
222	V	A	0.1167
223	K	A	-0.7730
224	Y	A	0.0000
225	R	A	0.0000
226	F	A	0.0000
227	R	A	0.0000
228	L	A	0.0000
229	V	A	0.0000
230	S	A	0.0000
231	I	A	0.0000
232	S	A	0.0000
233	C	A	0.0000
234	D	A	-0.2420
235	P	A	0.0000
236	N	A	0.0000
237	F	A	0.0000
238	T	A	-0.1645
239	F	A	0.0000
240	S	A	0.0000
241	I	A	0.0000
242	D	A	0.0000
243	N	A	-0.9965
244	H	A	0.0000
245	T	A	-0.0960
246	M	A	0.0000
247	T	A	0.2223
248	I	A	0.0000
249	I	A	0.0000
250	E	A	0.0000
251	V	A	0.0000
252	D	A	0.0000
253	G	A	-0.1371
254	N	A	-0.3586
255	N	A	-0.3687
256	V	A	0.0000
257	E	A	-1.4036
258	P	A	-0.3809
259	V	A	0.5189
260	V	A	1.8121
261	A	A	0.0000
262	D	A	-0.2457
263	S	A	0.0000
264	I	A	0.0000
265	Q	A	-0.4978
266	I	A	0.0000
267	F	A	0.0000
268	A	A	0.0000
269	S	A	0.0000
270	Q	A	0.0000
271	R	A	0.0000
272	Y	A	0.0000
273	S	A	0.0000
274	F	A	0.0000
275	I	A	0.0000
276	L	A	0.0000
277	N	A	-0.8186
278	A	A	0.0000
279	N	A	-1.3280
280	Q	A	-0.5462
281	T	A	-0.0429
282	I	A	0.4307
283	S	A	-0.0208
284	N	A	-0.1662
285	Y	A	0.0000
286	W	A	0.1212
287	I	A	0.0000
288	R	A	0.0000
289	A	A	0.0000
290	Q	A	-0.6607
291	P	A	0.0000
292	N	A	-0.6127
293	V	A	0.5793
294	G	A	-0.1164
295	T	A	-0.0991
296	T	A	-0.0724
297	G	A	0.1309
298	Y	A	0.9735
299	D	A	-1.6372
300	G	A	-0.7904
301	G	A	0.0000
302	I	A	0.0000
303	N	A	0.0000
304	S	A	0.0000
305	A	A	0.0000
306	I	A	0.0000
307	L	A	0.0000
308	R	A	-0.2235
309	Y	A	0.0000
310	L	A	1.3711
311	S	A	0.0409
312	A	A	-0.0778
313	S	A	-0.5419
314	E	A	-2.1953
315	E	A	-2.3223
316	E	A	-1.2385
317	P	A	0.0000
318	T	A	-0.0730
319	T	A	-0.0703
320	P	A	-0.4397
321	E	A	-0.7168
322	V	A	1.5778
323	T	A	0.2506
324	T	A	-0.0482
325	T	A	-0.3063
326	N	A	-1.0278
327	L	A	1.2317
328	L	A	0.4335
329	A	A	0.0286
330	E	A	-0.2420
331	T	A	-0.1294
332	S	A	-0.1478
333	L	A	0.0000
334	I	A	0.4108
335	P	A	0.0000
336	L	A	0.0600
337	E	A	-1.9420
338	N	A	-1.6083
339	P	A	-0.3560
340	G	A	-0.4717
341	A	A	-0.0848
342	P	A	-0.0521
343	G	A	-0.2173
344	G	A	-0.5288
345	S	A	-0.6218
346	D	A	-1.8729
347	P	A	-0.5660
348	A	A	-0.3591
349	D	A	-1.7298
350	V	A	-0.0200
351	A	A	0.1489
352	Y	A	0.1588
353	N	A	-1.2025
354	L	A	0.0000
355	A	A	0.0514
356	I	A	0.2106
357	T	A	0.1644
358	F	A	0.5899
359	N	A	-1.2068
360	G	A	-0.7341
361	S	A	-0.2968
362	A	A	-0.0320
363	F	A	0.0000
364	A	A	0.0000
365	I	A	0.0000
366	N	A	-0.5766
367	D	A	-1.8345
368	A	A	-0.3223
369	T	A	-0.0211
370	Y	A	0.0000
371	I	A	0.3135
372	E	A	-2.0289
373	E	A	-2.1418
374	V	A	0.0000
375	S	A	-0.0657
376	L	A	0.7550
377	P	A	0.0000
378	V	A	0.0000
379	L	A	0.0000
380	L	A	0.2879
381	Q	A	0.0000
382	I	A	0.0000
383	L	A	0.2188
384	S	A	-0.2547
385	G	A	-0.5082
386	T	A	-0.1134
387	T	A	-0.0913
388	S	A	-0.1914
389	A	A	-0.2221
390	Q	A	-1.5172
391	D	A	-2.0065
392	L	A	0.0000
393	L	A	1.2853
394	P	A	0.0000
395	D	A	-1.6884
396	G	A	-0.6393
397	S	A	0.0000
398	V	A	0.2133
399	Y	A	0.2293
400	T	A	0.0128
401	L	A	0.0000
402	P	A	-0.4527
403	R	A	-1.5847
404	N	A	-1.5120
405	S	A	0.0000
406	T	A	-0.0238
407	I	A	0.0000
408	E	A	-0.3445
409	L	A	0.0000
410	S	A	0.0000
411	L	A	0.0000
412	P	A	-0.1604
413	G	A	-0.4122
414	G	A	-0.6050
415	A	A	0.2554
416	V	A	1.6899
417	G	A	-0.1586
418	S	A	-0.1664
419	P	A	-0.0642
420	H	A	0.0000
421	P	A	0.0000
422	F	A	0.0000
423	H	A	0.0000
424	L	A	0.0000
425	H	A	0.0000
426	G	A	0.0000
427	H	A	0.0000
428	A	A	0.0109
429	F	A	0.0000
430	D	A	0.0000
431	V	A	0.0000
432	I	A	0.0000
433	R	A	-0.2071
434	S	A	0.0000
435	A	A	-0.0669
436	G	A	-0.4691
437	S	A	-0.1553
438	S	A	-0.2316
439	T	A	-0.0408
440	Y	A	0.2542
441	N	A	-0.1384
442	Y	A	1.3459
443	V	A	1.8677
444	N	A	-0.2367
445	P	A	0.0000
446	P	A	0.0000
447	R	A	-0.5254
448	R	A	0.0000
449	D	A	0.0000
450	T	A	0.0000
451	V	A	0.0000
452	S	A	-0.0215
453	L	A	0.0000
454	G	A	0.0000
455	E	A	-1.8864
456	T	A	-0.5420
457	G	A	-0.5278
458	D	A	-0.4075
459	N	A	-0.3676
460	V	A	0.0000
461	T	A	0.0000
462	I	A	0.0000
463	R	A	-0.2268
464	F	A	0.0000
465	S	A	-0.0974
466	T	A	0.0000
467	Y	A	0.8670
468	N	A	0.0000
469	P	A	0.0000
470	G	A	0.0000
471	P	A	0.0000
472	W	A	0.0000
473	I	A	0.0000
474	L	A	0.0000
475	H	A	0.0000
476	C	A	0.0000
477	H	A	0.0000
478	I	A	0.0000
479	D	A	0.0000
480	W	A	0.0000
481	H	A	0.0137
482	L	A	-0.0023
483	D	A	-0.8171
484	I	A	0.5106
485	G	A	0.0000
486	L	A	0.0000
487	A	A	0.0000
488	V	A	0.0000
489	V	A	0.0000
490	M	A	0.0000
491	A	A	0.0000
492	E	A	0.0000
493	A	A	0.0000
494	P	A	-0.0704
495	S	A	-0.3034
496	D	A	-0.5098
497	I	A	0.0000
498	E	A	-2.0530
499	N	A	-1.5331
500	L	A	0.1524
501	A	A	0.0000
502	V	A	1.7694
503	T	A	-0.0212
504	D	A	-1.8297
505	S	A	-0.5231
506	W	A	0.0000
507	S	A	-0.5375
508	D	A	-1.7934
509	L	A	-0.0778
510	C	A	0.2452
511	S	A	-0.1799
512	T	A	0.1304
513	Y	A	1.3091
514	A	A	-0.0370
515	D	A	-2.0023
516	Q	A	-1.6433
517	D	A	-0.8760
518	S	A	-0.1532