Project name: 2w97 modified

Chain sequence(s)	A: PEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV; E: KKRYDREFLLGFQ
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.875
• Maximal score value: 2.221
• Average score: -1.0443
• Total score value: -208.8513

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
31	P	A	-0.7471
32	E	A	-1.7954
33	H	A	-1.1042
34	Y	A	0.6473
35	I	A	0.6746
36	K	A	-1.0789
37	H	A	-0.9874
38	P	A	-1.4251
39	L	A	0.0000
40	Q	A	-2.2189
41	N	A	-2.2699
42	R	A	-3.0142
43	W	A	0.0000
44	A	A	0.0000
45	L	A	0.0000
46	W	A	-0.1382
47	F	A	-0.2152
48	F	A	0.0000
49	K	A	-2.1227
50	N	A	-2.0615
51	D	A	-2.6434
52	K	A	-2.8976
53	S	A	-2.0845
54	K	A	-2.7255
55	T	A	-1.3446
56	W	A	-0.7615
57	Q	A	-1.0070
58	A	A	-1.1986
59	N	A	-1.7861
60	L	A	-0.9750
61	R	A	-1.4696
62	L	A	-0.1987
63	I	A	0.3078
64	S	A	-0.4123
65	K	A	-1.9291
66	F	A	0.0000
67	D	A	-2.6376
68	T	A	-1.6420
69	V	A	0.0000
70	E	A	-1.2616
71	D	A	-1.4633
72	F	A	0.0000
73	W	A	0.0000
74	A	A	-0.8929
75	L	A	-0.6808
76	Y	A	-0.8720
77	N	A	-1.8252
78	H	A	-1.4320
79	I	A	-0.7681
80	Q	A	-1.3065
81	L	A	-0.5780
82	S	A	0.0000
83	S	A	-1.3642
84	N	A	-1.4438
85	L	A	0.0000
86	M	A	-0.0901
87	P	A	-0.6823
88	G	A	-0.8646
89	C	A	0.0000
90	D	A	0.0000
91	Y	A	0.0000
92	S	A	0.0000
93	L	A	0.0000
94	F	A	0.0000
95	K	A	0.0000
96	D	A	-1.9554
97	G	A	-1.3935
98	I	A	0.0000
99	E	A	-1.8951
100	P	A	0.0000
101	M	A	-1.1858
102	W	A	-1.7306
103	E	A	-3.1300
104	D	A	-3.1633
105	E	A	-3.7088
106	K	A	-3.0850
107	N	A	0.0000
108	K	A	-3.7198
109	R	A	-3.6168
110	G	A	0.0000
111	G	A	0.0000
112	R	A	-0.5274
113	W	A	0.0000
114	L	A	0.0000
115	I	A	0.0000
116	T	A	-0.5388
117	L	A	0.0000
118	N	A	-3.2725
119	K	A	-3.8750
120	Q	A	-3.3450
121	Q	A	-2.9398
122	R	A	-3.3609
123	R	A	-3.5851
124	S	A	-2.5133
125	D	A	-2.3247
126	L	A	0.0000
127	D	A	-1.6132
128	R	A	-2.1939
129	F	A	0.0000
130	W	A	0.0000
131	L	A	-0.3689
132	E	A	0.0000
133	T	A	0.0000
134	L	A	0.0000
135	L	A	0.0000
136	C	A	0.0000
137	L	A	0.0000
138	I	A	0.0000
139	G	A	0.0000
140	E	A	0.0000
141	S	A	0.0000
142	F	A	0.0000
143	D	A	-2.9181
144	D	A	-2.9581
145	Y	A	-2.0613
146	S	A	0.0000
147	D	A	-2.3942
148	D	A	-1.4481
149	V	A	0.0000
150	C	A	0.0000
151	G	A	0.0000
152	A	A	0.0000
153	V	A	0.0000
154	V	A	0.0000
155	N	A	-0.3957
156	V	A	0.0000
157	R	A	-1.3550
158	A	A	-1.3858
159	K	A	-2.3442
160	G	A	-2.2068
161	D	A	0.0000
162	K	A	-0.7947
163	I	A	0.0000
164	A	A	0.0000
165	I	A	0.0000
166	W	A	0.0000
167	T	A	0.0000
168	T	A	-2.0600
169	E	A	-2.2792
170	C	A	0.0000
171	E	A	-3.4470
172	N	A	-2.8836
173	R	A	-3.7587
174	E	A	-3.1582
175	A	A	0.0000
176	V	A	0.0000
177	T	A	-1.4461
178	H	A	-1.9538
179	I	A	0.0000
180	G	A	0.0000
181	R	A	-2.1868
182	V	A	-1.6782
183	Y	A	0.0000
184	K	A	-1.4280
185	E	A	-2.6256
186	R	A	-1.7135
187	L	A	0.0000
188	G	A	-1.2190
189	L	A	-0.4794
190	P	A	-0.4982
191	P	A	-0.8921
192	K	A	-0.7869
193	I	A	1.1024
194	V	A	2.2210
195	I	A	0.0000
196	G	A	0.0085
197	Y	A	0.0000
198	Q	A	0.0000
199	S	A	0.0000
200	H	A	0.0000
201	A	A	-1.0163
202	D	A	-1.2894
203	T	A	0.0000
204	A	A	-0.4033
205	T	A	-0.7782
206	K	A	-1.6617
207	S	A	-1.1243
208	G	A	-0.8981
209	S	A	-0.8309
210	T	A	-1.1911
211	T	A	0.0000
212	K	A	-2.9943
213	N	A	-2.5695
214	R	A	-2.7342
215	F	A	-0.6622
216	V	A	1.3014
217	V	A	0.9478
621	K	E	-3.0268
622	K	E	-2.4963
623	R	E	-3.3826
624	Y	E	-2.3663
625	D	E	-2.9542
626	R	E	-2.8442
627	E	E	-2.4215
628	F	E	-1.0385
629	L	E	0.0000
630	L	E	-0.9627
631	G	E	-0.7597
632	F	E	-0.3117
633	Q	E	-1.1280