Project name: 6azk:B
Status: done
submitted: 2019-03-20 16:18:27, status changed: 2019-03-20 17:33:05
Settings
|
Chain sequence(s)
|
B: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNNSLQQSSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.4946
-
Maximal score value
-
2.4114
-
Average score
-
-0.4876
-
Total score value
-
-106.7743
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
B |
-1.5682 |
|
| 2 |
V |
B |
-1.0347 |
|
| 3 |
Q |
B |
-1.9283 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
K |
B |
-2.3331 |
|
| 6 |
Q |
B |
0.0000 |
|
| 7 |
S |
B |
-0.8042 |
|
| 8 |
G |
B |
-1.0617 |
|
| 9 |
P |
B |
-0.3489 |
|
| 10 |
G |
B |
-0.4376 |
|
| 11 |
L |
B |
0.1469 |
|
| 12 |
V |
B |
-0.4502 |
|
| 13 |
Q |
B |
-0.9462 |
|
| 14 |
P |
B |
-1.4326 |
|
| 15 |
S |
B |
-1.5246 |
|
| 16 |
Q |
B |
-1.8915 |
|
| 17 |
S |
B |
-1.7374 |
|
| 18 |
L |
B |
0.0000 |
|
| 19 |
S |
B |
-0.7419 |
|
| 20 |
I |
B |
0.0000 |
|
| 21 |
T |
B |
-0.5414 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
T |
B |
-1.2143 |
|
| 24 |
V |
B |
0.0000 |
|
| 25 |
S |
B |
-1.3810 |
|
| 26 |
G |
B |
-1.0894 |
|
| 27 |
F |
B |
-0.6016 |
|
| 28 |
S |
B |
-0.8930 |
|
| 29 |
L |
B |
0.0000 |
|
| 30 |
T |
B |
-0.9248 |
|
| 31 |
N |
B |
-0.8944 |
|
| 32 |
Y |
B |
0.4090 |
|
| 33 |
G |
B |
0.0000 |
|
| 34 |
V |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.2635 |
|
| 40 |
S |
B |
0.0000 |
|
| 41 |
P |
B |
-1.0974 |
|
| 42 |
G |
B |
-1.6259 |
|
| 43 |
K |
B |
-2.0112 |
|
| 44 |
G |
B |
-0.6717 |
|
| 45 |
L |
B |
0.7402 |
|
| 46 |
E |
B |
0.0611 |
|
| 47 |
W |
B |
0.4897 |
|
| 48 |
L |
B |
0.0000 |
|
| 49 |
G |
B |
0.0000 |
|
| 50 |
V |
B |
0.0000 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
W |
B |
-0.6316 |
|
| 53 |
S |
B |
-0.6951 |
|
| 54 |
G |
B |
-1.2432 |
|
| 55 |
G |
B |
-1.5422 |
|
| 56 |
N |
B |
-1.9491 |
|
| 57 |
T |
B |
-1.5038 |
|
| 58 |
D |
B |
-1.4880 |
|
| 59 |
Y |
B |
-0.6765 |
|
| 60 |
N |
B |
-0.6838 |
|
| 61 |
T |
B |
-0.5330 |
|
| 62 |
P |
B |
-0.4838 |
|
| 63 |
F |
B |
0.0000 |
|
| 64 |
T |
B |
-0.6231 |
|
| 65 |
S |
B |
-0.7092 |
|
| 66 |
R |
B |
-1.2337 |
|
| 67 |
L |
B |
0.0000 |
|
| 68 |
S |
B |
-1.2189 |
|
| 69 |
I |
B |
0.0000 |
|
| 70 |
N |
B |
-1.7655 |
|
| 71 |
K |
B |
-1.4714 |
|
| 72 |
D |
B |
-1.8092 |
|
| 73 |
N |
B |
-2.2314 |
|
| 74 |
S |
B |
-1.6858 |
|
| 75 |
K |
B |
-2.3814 |
|
| 76 |
S |
B |
-1.5769 |
|
| 77 |
Q |
B |
-1.5430 |
|
| 78 |
V |
B |
0.0000 |
|
| 79 |
F |
B |
-0.3202 |
|
| 80 |
F |
B |
0.0000 |
|
| 81 |
K |
B |
-1.7329 |
|
| 82 |
M |
B |
0.0000 |
|
| 83 |
N |
B |
-2.2915 |
|
| 84 |
S |
B |
-1.6692 |
|
| 85 |
L |
B |
0.0000 |
|
| 86 |
Q |
B |
-2.1661 |
|
| 87 |
S |
B |
-1.5065 |
|
| 88 |
N |
B |
-2.0886 |
|
| 89 |
D |
B |
0.0000 |
|
| 90 |
T |
B |
-0.6431 |
|
| 91 |
A |
B |
0.0000 |
|
| 92 |
I |
B |
0.5622 |
|
| 93 |
Y |
B |
0.0000 |
|
| 94 |
Y |
B |
0.1201 |
|
| 95 |
C |
B |
0.0000 |
|
| 96 |
A |
B |
0.0000 |
|
| 97 |
R |
B |
0.0000 |
|
| 98 |
A |
B |
0.0000 |
|
| 99 |
L |
B |
1.9148 |
|
| 100 |
T |
B |
1.4664 |
|
| 101 |
Y |
B |
2.0027 |
|
| 102 |
Y |
B |
1.8363 |
|
| 103 |
D |
B |
0.9371 |
|
| 104 |
Y |
B |
0.9285 |
|
| 105 |
E |
B |
-0.0461 |
|
| 106 |
F |
B |
0.6331 |
|
| 107 |
A |
B |
0.8161 |
|
| 108 |
Y |
B |
0.5435 |
|
| 109 |
W |
B |
0.0813 |
|
| 110 |
G |
B |
0.0000 |
|
| 111 |
Q |
B |
-1.4968 |
|
| 112 |
G |
B |
0.0000 |
|
| 113 |
T |
B |
0.0000 |
|
| 114 |
L |
B |
0.4935 |
|
| 115 |
V |
B |
0.0000 |
|
| 116 |
T |
B |
-0.1746 |
|
| 117 |
V |
B |
0.0000 |
|
| 118 |
S |
B |
-0.5068 |
|
| 119 |
A |
B |
-0.3686 |
|
| 120 |
A |
B |
-0.1854 |
|
| 121 |
S |
B |
-0.4270 |
|
| 122 |
T |
B |
-0.7211 |
|
| 123 |
K |
B |
-1.2107 |
|
| 124 |
G |
B |
-1.3240 |
|
| 125 |
P |
B |
0.0000 |
|
| 126 |
S |
B |
-0.0725 |
|
| 127 |
V |
B |
0.0000 |
|
| 128 |
F |
B |
0.9748 |
|
| 129 |
P |
B |
0.0535 |
|
| 130 |
L |
B |
0.5236 |
|
| 131 |
A |
B |
-0.6668 |
|
| 132 |
P |
B |
0.0000 |
|
| 133 |
S |
B |
-1.0566 |
|
| 134 |
S |
B |
-1.1977 |
|
| 135 |
K |
B |
-1.9062 |
|
| 136 |
S |
B |
-1.0121 |
|
| 137 |
T |
B |
-1.0572 |
|
| 138 |
S |
B |
-0.9715 |
|
| 139 |
G |
B |
-0.8553 |
|
| 140 |
G |
B |
-0.9189 |
|
| 141 |
T |
B |
-0.6869 |
|
| 142 |
A |
B |
0.0000 |
|
| 143 |
A |
B |
-0.2196 |
|
| 144 |
L |
B |
0.0000 |
|
| 145 |
G |
B |
0.0000 |
|
| 146 |
C |
B |
0.0000 |
|
| 147 |
L |
B |
0.6873 |
|
| 148 |
V |
B |
0.0000 |
|
| 149 |
K |
B |
-0.2477 |
|
| 150 |
D |
B |
-0.6543 |
|
| 151 |
Y |
B |
0.0000 |
|
| 152 |
F |
B |
0.0000 |
|
| 153 |
P |
B |
0.0000 |
|
| 154 |
E |
B |
-0.1099 |
|
| 155 |
P |
B |
-0.4493 |
|
| 156 |
V |
B |
-0.4905 |
|
| 157 |
T |
B |
-0.4477 |
|
| 158 |
V |
B |
-0.3011 |
|
| 159 |
S |
B |
-0.3014 |
|
| 160 |
W |
B |
0.0000 |
|
| 161 |
N |
B |
-0.9147 |
|
| 162 |
S |
B |
-0.6373 |
|
| 163 |
G |
B |
-0.5637 |
|
| 164 |
A |
B |
-0.2828 |
|
| 165 |
L |
B |
-0.0833 |
|
| 166 |
T |
B |
-0.3305 |
|
| 167 |
S |
B |
-0.3448 |
|
| 168 |
G |
B |
-0.3984 |
|
| 169 |
V |
B |
-0.0843 |
|
| 170 |
H |
B |
-0.5491 |
|
| 171 |
T |
B |
0.1289 |
|
| 172 |
F |
B |
0.9694 |
|
| 173 |
P |
B |
0.7277 |
|
| 174 |
A |
B |
1.2708 |
|
| 175 |
V |
B |
2.4114 |
|
| 176 |
L |
B |
1.9904 |
|
| 177 |
Q |
B |
0.6021 |
|
| 178 |
S |
B |
0.0351 |
|
| 179 |
S |
B |
-0.2538 |
|
| 180 |
G |
B |
0.1691 |
|
| 181 |
L |
B |
0.2482 |
|
| 182 |
Y |
B |
0.7789 |
|
| 183 |
S |
B |
0.0000 |
|
| 184 |
L |
B |
0.0000 |
|
| 185 |
S |
B |
0.6485 |
|
| 186 |
S |
B |
0.0000 |
|
| 187 |
V |
B |
0.3355 |
|
| 188 |
V |
B |
0.0000 |
|
| 189 |
T |
B |
-0.2201 |
|
| 190 |
V |
B |
0.0000 |
|
| 191 |
P |
B |
-0.5520 |
|
| 192 |
S |
B |
-0.6272 |
|
| 193 |
S |
B |
-0.6095 |
|
| 194 |
S |
B |
-0.6692 |
|
| 195 |
L |
B |
-0.8655 |
|
| 196 |
G |
B |
-1.0037 |
|
| 197 |
T |
B |
-0.7904 |
|
| 198 |
Q |
B |
-1.3545 |
|
| 199 |
T |
B |
-1.2611 |
|
| 200 |
Y |
B |
0.0000 |
|
| 201 |
I |
B |
-1.3545 |
|
| 202 |
C |
B |
0.0000 |
|
| 203 |
N |
B |
-1.2198 |
|
| 204 |
V |
B |
0.0000 |
|
| 205 |
N |
B |
-1.5342 |
|
| 206 |
H |
B |
0.0000 |
|
| 207 |
K |
B |
-2.4092 |
|
| 208 |
P |
B |
-1.4305 |
|
| 209 |
S |
B |
-1.6667 |
|
| 210 |
N |
B |
-2.4305 |
|
| 211 |
T |
B |
-1.9009 |
|
| 212 |
K |
B |
-2.3894 |
|
| 213 |
V |
B |
-1.2488 |
|
| 214 |
D |
B |
-1.9543 |
|
| 215 |
K |
B |
-1.8183 |
|
| 216 |
R |
B |
-2.4946 |
|
| 217 |
V |
B |
0.0000 |
|
| 218 |
E |
B |
-2.4762 |
|
| 219 |
P |
B |
-1.1555 |
|