Project name: 1d456cd88e993d6
Status: done
submitted: 2018-12-03 12:07:49, status changed: 2018-12-03 12:14:34
Settings
|
Chain sequence(s)
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A: LIVTQTMMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLLRVYVEEELKPTPEGDLEILLQKWENGECAQKKIIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMMENSAEPEQSLACQCLVRTPEVDDEALEKFDKKALKALPMHIRLSSFNPTQLEEQCHI
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
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-3.8183
-
Maximal score value
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1.2071
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Average score
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-1.158
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Total score value
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-187.6001
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
L |
A |
1.2071 |
|
| 2 |
I |
A |
0.5994 |
|
| 3 |
V |
A |
0.0000 |
|
| 4 |
T |
A |
0.2796 |
|
| 5 |
Q |
A |
-0.4761 |
|
| 6 |
T |
A |
-0.6606 |
|
| 7 |
M |
A |
-1.1993 |
|
| 8 |
K |
A |
-1.9558 |
|
| 9 |
G |
A |
-1.3843 |
|
| 10 |
L |
A |
0.0000 |
|
| 11 |
D |
A |
-1.4899 |
|
| 12 |
I |
A |
-1.3761 |
|
| 13 |
Q |
A |
-2.1793 |
|
| 14 |
K |
A |
-2.4806 |
|
| 15 |
V |
A |
0.0000 |
|
| 16 |
A |
A |
-1.2518 |
|
| 17 |
G |
A |
-1.0787 |
|
| 18 |
T |
A |
-0.8277 |
|
| 19 |
W |
A |
0.0000 |
|
| 20 |
Y |
A |
-0.8712 |
|
| 21 |
S |
A |
0.0000 |
|
| 22 |
L |
A |
0.0000 |
|
| 23 |
A |
A |
0.0000 |
|
| 24 |
M |
A |
0.0000 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
A |
A |
0.0000 |
|
| 27 |
S |
A |
-1.0654 |
|
| 28 |
D |
A |
-1.1814 |
|
| 29 |
I |
A |
0.2719 |
|
| 30 |
S |
A |
-0.3220 |
|
| 31 |
L |
A |
-0.2739 |
|
| 32 |
L |
A |
0.0000 |
|
| 33 |
D |
A |
-1.8521 |
|
| 34 |
A |
A |
-1.3080 |
|
| 35 |
Q |
A |
-1.9702 |
|
| 36 |
S |
A |
-2.0557 |
|
| 37 |
A |
A |
-1.0742 |
|
| 38 |
P |
A |
-0.7899 |
|
| 39 |
L |
A |
-0.3345 |
|
| 40 |
R |
A |
-0.8018 |
|
| 41 |
V |
A |
0.0000 |
|
| 42 |
Y |
A |
0.0000 |
|
| 43 |
V |
A |
0.0000 |
|
| 44 |
E |
A |
-1.9584 |
|
| 45 |
E |
A |
-1.6932 |
|
| 46 |
L |
A |
0.0000 |
|
| 47 |
K |
A |
-1.4142 |
|
| 48 |
P |
A |
-1.7296 |
|
| 49 |
T |
A |
-1.4636 |
|
| 50 |
P |
A |
-1.5140 |
|
| 51 |
E |
A |
-2.3146 |
|
| 52 |
G |
A |
0.0000 |
|
| 53 |
D |
A |
-2.0002 |
|
| 54 |
L |
A |
0.0000 |
|
| 55 |
E |
A |
-0.9890 |
|
| 56 |
I |
A |
0.0000 |
|
| 57 |
L |
A |
-1.6646 |
|
| 58 |
L |
A |
0.0000 |
|
| 59 |
Q |
A |
-2.0828 |
|
| 60 |
K |
A |
-2.1189 |
|
| 61 |
W |
A |
-2.5087 |
|
| 62 |
E |
A |
-3.4519 |
|
| 63 |
N |
A |
-2.9783 |
|
| 64 |
G |
A |
-2.5602 |
|
| 65 |
E |
A |
-3.3412 |
|
| 66 |
C |
A |
-2.1871 |
|
| 67 |
A |
A |
-2.3078 |
|
| 68 |
Q |
A |
-2.7662 |
|
| 69 |
K |
A |
-2.4912 |
|
| 70 |
K |
A |
-2.1654 |
|
| 71 |
I |
A |
-0.7326 |
|
| 72 |
I |
A |
-0.4367 |
|
| 73 |
A |
A |
0.0000 |
|
| 74 |
E |
A |
-2.2911 |
|
| 75 |
K |
A |
-1.9850 |
|
| 76 |
T |
A |
-1.4089 |
|
| 77 |
K |
A |
-1.3252 |
|
| 78 |
I |
A |
-0.0394 |
|
| 79 |
P |
A |
-0.5657 |
|
| 80 |
A |
A |
0.0000 |
|
| 81 |
V |
A |
-0.4517 |
|
| 82 |
F |
A |
0.0000 |
|
| 83 |
K |
A |
-2.2847 |
|
| 84 |
I |
A |
-2.1074 |
|
| 85 |
D |
A |
-2.6145 |
|
| 86 |
A |
A |
-1.3190 |
|
| 87 |
L |
A |
0.0563 |
|
| 88 |
N |
A |
-1.8684 |
|
| 89 |
E |
A |
-3.1798 |
|
| 90 |
N |
A |
-2.3441 |
|
| 91 |
K |
A |
-1.7411 |
|
| 92 |
V |
A |
0.0000 |
|
| 93 |
L |
A |
0.0000 |
|
| 94 |
V |
A |
0.0000 |
|
| 95 |
L |
A |
0.0000 |
|
| 96 |
D |
A |
-0.9441 |
|
| 97 |
T |
A |
0.0000 |
|
| 98 |
D |
A |
-1.5267 |
|
| 99 |
Y |
A |
-1.9002 |
|
| 100 |
K |
A |
-2.6927 |
|
| 101 |
K |
A |
-2.6423 |
|
| 102 |
Y |
A |
0.0000 |
|
| 103 |
L |
A |
0.0000 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
F |
A |
0.0000 |
|
| 106 |
C |
A |
0.0000 |
|
| 107 |
M |
A |
-0.3006 |
|
| 108 |
E |
A |
-0.8713 |
|
| 109 |
N |
A |
-2.0332 |
|
| 110 |
S |
A |
-1.8164 |
|
| 111 |
A |
A |
-2.4917 |
|
| 112 |
E |
A |
-2.9761 |
|
| 113 |
P |
A |
-2.8163 |
|
| 114 |
E |
A |
-3.4840 |
|
| 115 |
Q |
A |
-2.7012 |
|
| 116 |
S |
A |
-1.8309 |
|
| 117 |
L |
A |
0.0000 |
|
| 118 |
A |
A |
0.0000 |
|
| 119 |
C |
A |
0.0000 |
|
| 120 |
Q |
A |
0.0000 |
|
| 121 |
C |
A |
0.0000 |
|
| 122 |
L |
A |
0.0000 |
|
| 123 |
V |
A |
0.0000 |
|
| 124 |
R |
A |
-1.6128 |
|
| 125 |
T |
A |
-1.2345 |
|
| 126 |
P |
A |
-1.4046 |
|
| 127 |
E |
A |
-1.8922 |
|
| 128 |
V |
A |
-0.5358 |
|
| 129 |
D |
A |
-2.0083 |
|
| 130 |
D |
A |
-3.0970 |
|
| 131 |
E |
A |
-3.4021 |
|
| 132 |
A |
A |
0.0000 |
|
| 133 |
L |
A |
-2.3033 |
|
| 134 |
E |
A |
-3.8183 |
|
| 135 |
K |
A |
-2.9393 |
|
| 136 |
F |
A |
0.0000 |
|
| 137 |
D |
A |
-3.0982 |
|
| 138 |
K |
A |
-3.2657 |
|
| 139 |
A |
A |
0.0000 |
|
| 140 |
L |
A |
0.0000 |
|
| 141 |
K |
A |
-2.4344 |
|
| 142 |
A |
A |
-1.2133 |
|
| 143 |
L |
A |
0.0000 |
|
| 144 |
P |
A |
-0.8290 |
|
| 145 |
M |
A |
-0.9363 |
|
| 146 |
H |
A |
-1.0658 |
|
| 147 |
I |
A |
-0.9416 |
|
| 148 |
R |
A |
-1.9484 |
|
| 149 |
L |
A |
-0.8734 |
|
| 150 |
S |
A |
-0.4995 |
|
| 151 |
F |
A |
0.0000 |
|
| 152 |
N |
A |
-1.4623 |
|
| 153 |
P |
A |
-1.6115 |
|
| 154 |
T |
A |
-1.4144 |
|
| 155 |
Q |
A |
-1.3484 |
|
| 156 |
L |
A |
0.0000 |
|
| 157 |
E |
A |
-2.9771 |
|
| 158 |
E |
A |
-2.4616 |
|
| 159 |
Q |
A |
-2.3427 |
|
| 160 |
C |
A |
0.0000 |
|
| 161 |
H |
A |
0.0000 |
|
| 162 |
I |
A |
0.6420 |
|