Project name: 5hpm:B

Chain sequence(s)	B: QVQLKQSGPGLVQQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9012
• Maximal score value: 2.4477
• Average score: -0.5373
• Total score value: -116.0475

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	B	-1.4878
2	V	B	-0.8986
3	Q	B	-1.6658
4	L	B	0.0000
5	K	B	-2.2917
6	Q	B	0.0000
7	S	B	-0.8895
8	G	B	-1.0875
9	P	B	-0.3785
10	G	B	-0.3622
11	L	B	-0.0865
12	V	B	-0.8440
13	Q	B	-1.6508
14	P	B	-1.4469
15	S	B	-1.6618
16	Q	B	-2.0930
17	S	B	-1.9034
18	L	B	0.0000
19	S	B	-0.8008
20	I	B	0.0000
21	T	B	-0.5713
22	C	B	0.0000
23	T	B	-1.1587
24	V	B	0.0000
25	S	B	-1.0974
26	G	B	-1.0058
27	F	B	-0.5418
28	S	B	-0.9670
29	L	B	0.0000
30	T	B	-1.0037
31	N	B	-0.9116
32	Y	B	0.4056
33	G	B	0.0000
34	V	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.2196
40	S	B	-0.8683
41	P	B	-1.0718
42	G	B	-1.6055
43	K	B	-1.9707
44	G	B	-0.5783
45	L	B	0.8243
46	E	B	0.0000
47	W	B	0.4651
48	L	B	0.0000
49	G	B	0.0000
50	V	B	0.0000
51	I	B	0.0000
52	W	B	-0.6427
53	S	B	-0.7469
54	G	B	-1.1652
55	G	B	-1.6143
56	N	B	-2.0043
57	T	B	-1.5886
58	D	B	-1.6613
59	Y	B	-0.7407
60	N	B	-0.6604
61	T	B	-0.5350
62	P	B	-0.4652
63	F	B	0.0000
64	T	B	-0.6313
65	S	B	-0.7007
66	R	B	-1.2687
67	L	B	0.0000
68	S	B	-1.2636
69	I	B	0.0000
70	N	B	-1.8244
71	K	B	-1.5818
72	D	B	-1.9847
73	N	B	-2.5633
74	S	B	-1.8827
75	K	B	-2.4718
76	S	B	-1.7391
77	Q	B	-1.6213
78	V	B	0.0000
79	F	B	-0.3337
80	F	B	0.0000
81	K	B	-1.8804
82	M	B	0.0000
83	N	B	-2.3120
84	S	B	-1.7460
85	L	B	0.0000
86	Q	B	-2.1116
87	S	B	-1.5121
88	N	B	-2.0440
89	D	B	0.0000
90	T	B	-0.6506
91	A	B	0.0000
92	I	B	0.5313
93	Y	B	0.0000
94	Y	B	-0.0802
95	C	B	0.0000
96	A	B	0.0000
97	R	B	0.0000
98	A	B	0.0000
99	L	B	1.3666
100	T	B	1.1245
101	Y	B	1.8683
102	Y	B	1.5697
103	D	B	0.3399
104	Y	B	0.2066
105	E	B	-0.9977
106	F	B	0.1140
107	A	B	0.5048
108	Y	B	0.4083
109	W	B	0.0757
110	G	B	0.0000
111	Q	B	-1.5135
112	G	B	-0.6274
113	T	B	0.0000
114	L	B	0.4105
115	V	B	0.0000
116	T	B	-0.2945
117	V	B	0.0000
118	S	B	-0.7166
119	A	B	-0.4042
120	A	B	-0.3255
121	S	B	-0.5281
122	T	B	-0.7471
123	K	B	-1.2591
124	G	B	-1.3859
125	P	B	0.0000
126	S	B	-0.0661
127	V	B	0.0000
128	F	B	0.9406
129	P	B	-0.1441
130	L	B	0.3311
131	A	B	-0.9226
132	P	B	0.0000
133	S	B	-0.7508
138	S	B	-0.6539
139	G	B	-0.8614
140	G	B	-0.9381
141	T	B	-0.6586
142	A	B	-0.3880
143	A	B	0.0635
144	L	B	0.0000
145	G	B	0.0000
146	C	B	0.0000
147	L	B	0.7114
148	V	B	0.0000
149	K	B	-0.2155
150	D	B	-0.6370
151	Y	B	0.0000
152	F	B	0.0000
153	P	B	0.0000
154	E	B	-0.0850
155	P	B	-0.4651
156	V	B	-0.4897
157	T	B	-0.4623
158	V	B	-0.1644
159	S	B	-0.3804
160	W	B	0.0000
161	N	B	-0.8843
162	S	B	-0.6949
163	G	B	-0.6004
164	A	B	-0.2752
165	L	B	-0.0694
166	T	B	-0.3262
167	S	B	-0.3794
168	G	B	-0.4793
169	V	B	-0.0416
170	H	B	-0.5347
171	T	B	0.0441
172	F	B	0.6488
173	P	B	0.4208
174	A	B	1.2102
175	V	B	2.4477
176	L	B	2.1794
177	Q	B	0.6730
178	S	B	0.0774
179	S	B	-0.2192
180	G	B	0.2390
181	L	B	0.2819
182	Y	B	0.8700
183	S	B	0.0000
184	L	B	0.0000
185	S	B	0.5514
186	S	B	0.0000
187	V	B	0.4072
188	V	B	0.0000
189	T	B	-0.2152
190	V	B	0.0000
191	P	B	-0.5678
192	S	B	-0.6441
193	S	B	-0.6279
194	S	B	0.0000
195	L	B	-0.8148
196	G	B	-0.9877
197	T	B	-0.7573
198	Q	B	-1.2841
199	T	B	-1.2485
200	Y	B	0.0000
201	I	B	-1.4070
202	C	B	0.0000
203	N	B	-1.4323
204	V	B	0.0000
205	N	B	-1.8032
206	H	B	0.0000
207	K	B	-2.3926
208	P	B	-1.4331
209	S	B	-1.6966
210	N	B	-2.4028
211	T	B	-1.9473
212	K	B	-2.5340
213	V	B	-1.5999
214	D	B	-2.3396
215	K	B	-1.8610
216	R	B	-2.6240
217	V	B	0.0000
218	E	B	-2.9012
219	P	B	-1.8565
220	K	B	-2.2456