Project name: 4od2:A
Status: done
submitted: 2019-03-21 13:04:25, status changed: 2019-03-21 13:11:46
Settings
|
Chain sequence(s)
|
A: SELTQDPAVSVALGQTVRITCSGDSLRSYYASWYQQKPGQAPVLVIYGANNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCNSADSSGNHVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEGSTVEKTVAP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.2465
-
Maximal score value
-
1.8158
-
Average score
-
-0.749
-
Total score value
-
-156.5422
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
S |
A |
-1.2082 |
|
| 2 |
E |
A |
-1.7870 |
|
| 3 |
L |
A |
0.0000 |
|
| 4 |
T |
A |
-0.9414 |
|
| 5 |
Q |
A |
0.0000 |
|
| 6 |
D |
A |
-2.1047 |
|
| 7 |
P |
A |
-1.4372 |
|
| 8 |
A |
A |
-1.0876 |
|
| 9 |
V |
A |
-0.5675 |
|
| 10 |
S |
A |
-0.2792 |
|
| 11 |
V |
A |
0.0000 |
|
| 12 |
A |
A |
-0.0810 |
|
| 13 |
L |
A |
-0.0226 |
|
| 14 |
G |
A |
-0.7292 |
|
| 15 |
Q |
A |
-1.2139 |
|
| 16 |
T |
A |
-1.1001 |
|
| 17 |
V |
A |
-1.0713 |
|
| 18 |
R |
A |
-1.7772 |
|
| 19 |
I |
A |
0.0000 |
|
| 20 |
T |
A |
-0.8789 |
|
| 21 |
C |
A |
0.0000 |
|
| 22 |
S |
A |
-1.4334 |
|
| 23 |
G |
A |
-2.0595 |
|
| 24 |
D |
A |
-2.9296 |
|
| 25 |
S |
A |
0.0000 |
|
| 26 |
L |
A |
0.0000 |
|
| 27 |
R |
A |
-2.5814 |
|
| 28 |
S |
A |
-1.0680 |
|
| 29 |
Y |
A |
0.2523 |
|
| 30 |
Y |
A |
1.1755 |
|
| 31 |
A |
A |
0.6596 |
|
| 32 |
S |
A |
0.7640 |
|
| 33 |
W |
A |
0.0000 |
|
| 34 |
Y |
A |
0.9268 |
|
| 35 |
Q |
A |
0.0193 |
|
| 36 |
Q |
A |
-0.7368 |
|
| 37 |
K |
A |
-1.3186 |
|
| 38 |
P |
A |
-1.0492 |
|
| 39 |
G |
A |
-1.0064 |
|
| 40 |
Q |
A |
-0.8494 |
|
| 41 |
A |
A |
-0.2150 |
|
| 42 |
P |
A |
0.0491 |
|
| 43 |
V |
A |
1.0091 |
|
| 44 |
L |
A |
1.0974 |
|
| 45 |
V |
A |
0.0000 |
|
| 46 |
I |
A |
0.0000 |
|
| 47 |
Y |
A |
0.6649 |
|
| 48 |
G |
A |
0.2982 |
|
| 49 |
A |
A |
-0.4077 |
|
| 50 |
N |
A |
-1.4364 |
|
| 51 |
N |
A |
-1.4714 |
|
| 52 |
R |
A |
-1.5674 |
|
| 53 |
P |
A |
-0.5515 |
|
| 54 |
S |
A |
-0.8986 |
|
| 55 |
G |
A |
-0.8425 |
|
| 56 |
I |
A |
-0.5618 |
|
| 57 |
P |
A |
-1.2655 |
|
| 58 |
D |
A |
-2.2028 |
|
| 59 |
R |
A |
-1.3995 |
|
| 60 |
F |
A |
0.0000 |
|
| 61 |
S |
A |
-1.1824 |
|
| 62 |
G |
A |
0.0000 |
|
| 63 |
S |
A |
-0.6818 |
|
| 64 |
S |
A |
-0.7725 |
|
| 65 |
S |
A |
-1.0291 |
|
| 66 |
G |
A |
-1.8079 |
|
| 67 |
N |
A |
-2.1265 |
|
| 68 |
T |
A |
-1.1488 |
|
| 69 |
A |
A |
0.0000 |
|
| 70 |
S |
A |
0.0000 |
|
| 71 |
L |
A |
0.0000 |
|
| 72 |
T |
A |
-0.8746 |
|
| 73 |
I |
A |
0.0000 |
|
| 74 |
T |
A |
-1.1404 |
|
| 75 |
G |
A |
-0.8521 |
|
| 76 |
A |
A |
0.0000 |
|
| 77 |
Q |
A |
-1.4061 |
|
| 78 |
A |
A |
-1.1647 |
|
| 79 |
E |
A |
-2.1405 |
|
| 80 |
D |
A |
0.0000 |
|
| 81 |
E |
A |
-1.4987 |
|
| 82 |
A |
A |
0.0000 |
|
| 83 |
D |
A |
-1.0127 |
|
| 84 |
Y |
A |
0.0000 |
|
| 85 |
Y |
A |
0.3142 |
|
| 86 |
C |
A |
0.0000 |
|
| 87 |
N |
A |
1.1411 |
|
| 88 |
S |
A |
0.0000 |
|
| 89 |
A |
A |
0.3333 |
|
| 90 |
D |
A |
-0.9186 |
|
| 91 |
S |
A |
-1.4311 |
|
| 92 |
S |
A |
-0.8879 |
|
| 93 |
G |
A |
-1.1152 |
|
| 94 |
N |
A |
-1.6606 |
|
| 95 |
H |
A |
-0.9731 |
|
| 96 |
V |
A |
0.9949 |
|
| 97 |
V |
A |
0.7455 |
|
| 98 |
F |
A |
1.5117 |
|
| 99 |
G |
A |
0.0000 |
|
| 100 |
G |
A |
-0.8287 |
|
| 101 |
G |
A |
0.0000 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-1.5076 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
T |
A |
-0.3475 |
|
| 106 |
V |
A |
0.0000 |
|
| 107 |
L |
A |
-0.3874 |
|
| 108 |
G |
A |
-0.6440 |
|
| 109 |
Q |
A |
-1.3305 |
|
| 110 |
P |
A |
-1.3747 |
|
| 111 |
K |
A |
-2.2143 |
|
| 112 |
A |
A |
-1.3996 |
|
| 113 |
A |
A |
-0.7641 |
|
| 114 |
P |
A |
0.0000 |
|
| 115 |
S |
A |
-0.1169 |
|
| 116 |
V |
A |
-0.2056 |
|
| 117 |
T |
A |
0.3220 |
|
| 118 |
L |
A |
0.8355 |
|
| 119 |
F |
A |
1.8158 |
|
| 120 |
P |
A |
0.7911 |
|
| 121 |
P |
A |
0.0000 |
|
| 122 |
S |
A |
-0.9541 |
|
| 123 |
S |
A |
-1.8114 |
|
| 124 |
E |
A |
-2.8510 |
|
| 125 |
E |
A |
-2.5050 |
|
| 126 |
L |
A |
-2.4314 |
|
| 127 |
Q |
A |
-2.6355 |
|
| 128 |
A |
A |
-2.1926 |
|
| 129 |
N |
A |
-2.9784 |
|
| 130 |
K |
A |
-3.1310 |
|
| 131 |
A |
A |
0.0000 |
|
| 132 |
T |
A |
-0.1339 |
|
| 133 |
L |
A |
0.0000 |
|
| 134 |
V |
A |
1.2087 |
|
| 135 |
C |
A |
0.0000 |
|
| 136 |
L |
A |
1.1948 |
|
| 137 |
I |
A |
0.0000 |
|
| 138 |
S |
A |
-0.6392 |
|
| 139 |
D |
A |
-1.6001 |
|
| 140 |
F |
A |
0.0000 |
|
| 141 |
Y |
A |
0.0000 |
|
| 142 |
P |
A |
0.0000 |
|
| 143 |
G |
A |
-1.0762 |
|
| 144 |
A |
A |
-0.3373 |
|
| 145 |
V |
A |
-0.1122 |
|
| 146 |
T |
A |
-0.1168 |
|
| 147 |
V |
A |
0.1721 |
|
| 148 |
A |
A |
-0.4080 |
|
| 149 |
W |
A |
0.0000 |
|
| 150 |
K |
A |
-0.8806 |
|
| 151 |
A |
A |
0.0000 |
|
| 152 |
D |
A |
-1.4291 |
|
| 153 |
S |
A |
-0.9138 |
|
| 154 |
S |
A |
-0.7416 |
|
| 155 |
P |
A |
-0.8389 |
|
| 156 |
V |
A |
-0.8223 |
|
| 157 |
K |
A |
-1.8151 |
|
| 158 |
A |
A |
-0.9999 |
|
| 159 |
G |
A |
-0.8628 |
|
| 160 |
V |
A |
-0.8983 |
|
| 161 |
E |
A |
-1.8074 |
|
| 162 |
T |
A |
-0.7352 |
|
| 163 |
T |
A |
-0.4571 |
|
| 164 |
T |
A |
-0.1353 |
|
| 165 |
P |
A |
-0.5605 |
|
| 166 |
S |
A |
-1.3335 |
|
| 167 |
K |
A |
-2.7121 |
|
| 168 |
Q |
A |
-2.2074 |
|
| 169 |
S |
A |
-1.5845 |
|
| 170 |
N |
A |
-1.9653 |
|
| 171 |
N |
A |
-2.5174 |
|
| 172 |
K |
A |
-2.3207 |
|
| 173 |
Y |
A |
-1.5514 |
|
| 174 |
A |
A |
-0.7985 |
|
| 175 |
A |
A |
0.0000 |
|
| 176 |
S |
A |
0.1636 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
Y |
A |
0.1760 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
S |
A |
-0.7701 |
|
| 181 |
L |
A |
0.0000 |
|
| 182 |
T |
A |
-2.0225 |
|
| 183 |
P |
A |
-2.6525 |
|
| 184 |
E |
A |
-3.2465 |
|
| 185 |
Q |
A |
-2.4524 |
|
| 186 |
W |
A |
0.0000 |
|
| 187 |
K |
A |
-3.1487 |
|
| 188 |
S |
A |
-2.4098 |
|
| 189 |
H |
A |
-2.3858 |
|
| 190 |
K |
A |
-2.4336 |
|
| 191 |
S |
A |
-1.4748 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
S |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
Q |
A |
-0.9774 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-0.6928 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
E |
A |
-2.3066 |
|
| 200 |
G |
A |
-1.3926 |
|
| 201 |
S |
A |
-1.0658 |
|
| 202 |
T |
A |
-0.7209 |
|
| 203 |
V |
A |
-0.6465 |
|
| 204 |
E |
A |
-2.1126 |
|
| 205 |
K |
A |
-1.6106 |
|
| 206 |
T |
A |
-0.8047 |
|
| 207 |
V |
A |
0.0137 |
|
| 208 |
A |
A |
-0.8236 |
|
| 209 |
P |
A |
-1.1532 |
|