Project name: 3eyf

Chain sequence(s)	A: MEIVLTQSPATLSLSPGERATLSCRASQSVGGYLTWYQHKPGQAPRLLIFDASIRATGIPARFSGSGSGTDFTLTITRLEPEDFAVYYCQQRSMWPPVTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEQVRLVESGGGVVQPGGSLRLSCEGSGFKFGDHGIHWVRQAPGEGLQWLTVISSDGTDERYTDSVKGRFTISRDNSKNTMSLQMNNLRPEDMGLYYCARDGKCGGGRCYSGLLDYWGQGTMVTVSSASFKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4837
• Maximal score value: 1.1846
• Average score: -0.806
• Total score value: -353.0332

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
0	M	A	0.0998
1	E	A	-1.0454
2	I	A	0.0000
3	V	A	0.8966
4	L	A	0.0000
5	T	A	-0.7202
6	Q	A	0.0000
7	S	A	-0.7925
8	P	A	-0.3929
9	A	A	-0.3844
10	T	A	-0.1474
11	L	A	0.0540
12	S	A	-0.6556
13	L	A	-1.1119
14	S	A	-1.6773
15	P	A	-2.0484
16	G	A	0.0000
17	E	A	-2.6489
18	R	A	-2.9993
19	A	A	-1.5216
20	T	A	-0.6352
21	L	A	0.0000
22	S	A	-0.8011
23	C	A	0.0000
24	R	A	-2.3002
25	A	A	-1.1573
26	S	A	-0.9831
27	Q	A	-1.6630
28	S	A	-1.1967
29	V	A	0.0000
30	G	A	-0.3271
31	G	A	-0.2786
32	Y	A	0.5013
33	L	A	0.0000
34	T	A	0.0000
35	W	A	0.0000
36	Y	A	0.0000
37	Q	A	0.0000
38	H	A	0.0000
39	K	A	-1.9165
40	P	A	-1.4525
41	G	A	-1.6452
42	Q	A	-2.2451
43	A	A	-1.5676
44	P	A	0.0000
45	R	A	-1.1980
46	L	A	0.0000
47	L	A	0.0000
48	I	A	0.0000
49	F	A	0.3810
50	D	A	0.1560
51	A	A	-0.0479
52	S	A	0.1387
53	I	A	0.5744
54	R	A	-0.7425
55	A	A	-0.5964
56	T	A	-0.4901
57	G	A	-0.6494
58	I	A	-0.4872
59	P	A	-0.5617
60	A	A	-0.3429
61	R	A	-0.9787
62	F	A	0.0000
63	S	A	-0.4410
64	G	A	-0.3936
65	S	A	-0.7389
66	G	A	-1.2746
67	S	A	-1.1832
68	G	A	-1.4107
69	T	A	-1.7768
70	D	A	-2.0136
71	F	A	0.0000
72	T	A	-0.7610
73	L	A	0.0000
74	T	A	-0.8467
75	I	A	0.0000
76	T	A	-1.9683
77	R	A	-3.2094
78	L	A	0.0000
79	E	A	-2.2490
80	P	A	-2.0967
81	E	A	-2.6823
82	D	A	0.0000
83	F	A	-0.9269
84	A	A	0.0000
85	V	A	-0.3845
86	Y	A	0.0000
87	Y	A	0.0000
88	C	A	0.0000
89	Q	A	0.0000
90	Q	A	0.0000
91	R	A	0.0237
92	S	A	0.0216
93	M	A	0.1278
94	W	A	0.0281
95	P	A	-0.4216
96	P	A	-0.2019
97	V	A	0.1981
98	T	A	0.2038
99	F	A	-0.0444
100	G	A	-0.6580
101	Q	A	-1.6685
102	G	A	-1.1056
103	T	A	0.0000
104	K	A	-0.7576
105	L	A	0.0000
106	E	A	-0.9162
107	I	A	0.0000
108	K	A	-1.9089
109	R	A	-1.4612
110	T	A	-0.1499
111	V	A	0.5702
112	A	A	0.1272
113	A	A	-0.0296
114	P	A	0.0000
115	S	A	-0.1383
116	V	A	0.0085
117	F	A	0.0000
118	I	A	0.0000
119	F	A	0.0000
120	P	A	-0.4891
121	P	A	-0.5566
122	S	A	0.0000
123	D	A	-2.9165
124	E	A	-2.9475
125	Q	A	0.0000
126	L	A	-1.7909
127	K	A	-2.8221
128	S	A	-1.8034
129	G	A	-1.2577
130	T	A	-0.8789
131	A	A	0.0000
132	S	A	0.1420
133	V	A	0.0000
134	V	A	0.0000
135	C	A	0.0000
136	L	A	0.0000
137	L	A	0.0000
138	N	A	0.0000
139	N	A	-0.8724
140	F	A	0.0000
141	Y	A	0.0000
142	P	A	-1.2984
143	R	A	-1.8703
144	E	A	-2.8478
145	A	A	-2.1458
146	K	A	-2.4258
147	V	A	-1.0260
148	Q	A	-0.8515
149	W	A	0.0000
150	K	A	-0.7294
151	V	A	0.0000
152	D	A	-2.2227
153	N	A	-1.7903
154	A	A	-0.5916
155	L	A	0.0197
156	Q	A	-0.7079
157	S	A	-0.9304
158	G	A	-1.4953
159	N	A	-1.8617
160	S	A	-1.5223
161	Q	A	-1.6943
162	E	A	-1.6096
163	S	A	-0.6362
164	V	A	-0.6132
165	T	A	-1.3018
166	E	A	-2.3876
167	Q	A	-2.5166
168	D	A	-3.4779
169	S	A	-2.9511
170	K	A	-3.1123
171	D	A	-2.7247
172	S	A	0.0000
173	T	A	-1.7955
174	Y	A	0.0000
175	S	A	0.0000
176	L	A	0.0000
177	S	A	0.0000
178	S	A	0.0000
179	T	A	-0.8495
180	L	A	0.0000
181	T	A	-0.0428
182	L	A	0.1031
183	S	A	-0.4436
184	K	A	-1.6391
185	A	A	-1.4038
186	D	A	-1.8761
187	Y	A	0.0000
188	E	A	-3.4837
189	K	A	-3.4052
190	H	A	-3.0888
191	K	A	-3.2371
192	V	A	-1.8445
193	Y	A	0.0000
194	A	A	0.0000
195	C	A	0.0000
196	E	A	-0.5713
197	V	A	0.0000
198	T	A	-1.1650
199	H	A	0.0000
200	Q	A	-1.5403
201	G	A	-0.3541
202	L	A	-0.2584
203	S	A	-0.4134
204	S	A	-0.3743
205	P	A	-0.3897
206	V	A	0.3966
207	T	A	-0.1192
208	K	A	-0.2847
209	S	A	-0.6118
210	F	A	0.0000
211	N	A	-1.5937
212	R	A	-1.8271
213	G	A	-1.2649
1	Q	A	-1.3855
2	V	A	-1.0341
3	R	A	-1.3902
4	L	A	0.0000
5	V	A	-0.1509
6	E	A	-0.5371
7	S	A	-0.7502
8	G	A	-1.1427
9	G	A	-0.5534
10	G	A	-0.2429
11	V	A	0.3658
12	V	A	0.0000
13	Q	A	-1.8776
14	P	A	-1.8552
15	G	A	-1.9012
16	G	A	0.0000
17	S	A	-1.3978
18	L	A	-1.2322
19	R	A	-2.1789
20	L	A	0.0000
21	S	A	-0.9639
22	C	A	0.0000
23	E	A	-1.9860
24	G	A	-1.6205
25	S	A	-1.3480
26	G	A	-1.2140
27	F	A	-1.4455
28	K	A	-2.4251
29	F	A	0.0000
30	G	A	-2.7511
31	D	A	-2.7997
32	H	A	-1.9946
33	G	A	-1.2860
34	I	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	R	A	0.0000
39	Q	A	-0.5965
40	A	A	-1.0775
41	P	A	-1.1372
42	G	A	-1.7052
43	E	A	-2.5036
44	G	A	-1.6238
45	L	A	0.0000
46	Q	A	-0.7514
47	W	A	0.0000
48	L	A	0.0000
49	T	A	0.0000
50	V	A	0.0000
51	I	A	0.0000
52	S	A	-1.9549
53	S	A	-2.2874
54	D	A	-2.8035
55	G	A	-1.8936
56	T	A	-1.5455
57	D	A	-2.3257
58	E	A	-2.1016
59	R	A	-2.4368
60	Y	A	-1.9413
61	T	A	-1.7608
62	D	A	-2.7810
63	S	A	-1.6701
64	V	A	0.0000
65	K	A	-2.9482
66	G	A	-1.7637
67	R	A	-1.7331
68	F	A	0.0000
69	T	A	-0.9413
70	I	A	0.0000
71	S	A	-0.8485
72	R	A	-1.9896
73	D	A	-2.9706
74	N	A	-3.1207
75	S	A	-1.9359
76	K	A	-2.9544
77	N	A	-2.8424
78	T	A	-2.1353
79	M	A	0.0000
80	S	A	-1.1343
81	L	A	0.0000
82	Q	A	-1.1288
83	M	A	0.0000
84	N	A	-1.6356
85	N	A	-2.2287
86	L	A	0.0000
87	R	A	-2.9771
88	P	A	-2.0092
89	E	A	-2.4285
90	D	A	-1.6253
91	M	A	-0.4415
92	G	A	-0.1612
93	L	A	0.3840
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	-0.5938
99	D	A	0.0000
100	G	A	-1.1280
101	K	A	-1.9698
102	C	A	-1.3220
103	G	A	-1.3010
104	G	A	-1.4354
105	G	A	-1.8365
106	R	A	-2.3702
107	C	A	-1.2239
108	Y	A	-0.8487
109	S	A	0.0000
110	G	A	0.0000
111	L	A	0.0000
112	L	A	0.0000
113	D	A	-0.9980
114	Y	A	-0.4725
115	W	A	0.0000
116	G	A	0.0000
117	Q	A	-1.5908
118	G	A	-0.5887
119	T	A	-0.0113
120	M	A	0.6654
121	V	A	0.0000
122	T	A	-0.2719
123	V	A	0.0000
124	S	A	-0.8489
125	S	A	-0.5274
126	A	A	-0.0387
127	S	A	0.3541
128	F	A	1.1846
129	K	A	-0.3620
130	G	A	-1.0492
131	P	A	-0.4562
132	S	A	-0.3533
133	V	A	0.0000
134	F	A	0.0000
135	P	A	-1.4091
136	L	A	0.0000
137	A	A	-0.5411
138	P	A	-0.7191
139	S	A	-1.0022
140	S	A	-1.1130
141	K	A	-1.9192
142	S	A	0.0000
143	T	A	-0.8014
144	S	A	-0.7341
145	G	A	-0.8198
146	G	A	-0.8418
147	T	A	-0.5941
148	A	A	0.0000
149	A	A	0.0000
150	L	A	0.0000
151	G	A	0.0000
152	C	A	0.0000
153	L	A	0.0000
154	V	A	0.0000
155	K	A	-0.2973
156	D	A	-0.3588
157	Y	A	0.0000
158	F	A	0.0000
159	P	A	-0.3137
160	E	A	-0.7263
161	P	A	-1.0570
162	V	A	-1.1258
163	T	A	-0.9082
164	V	A	-0.3085
165	S	A	-0.4145
166	W	A	0.0000
167	N	A	-0.8713
168	S	A	-0.7237
169	G	A	-0.5133
170	A	A	-0.2632
171	L	A	-0.0131
172	T	A	-0.1898
173	S	A	-0.1878
174	G	A	-0.1907
175	V	A	0.0835
176	H	A	-0.4278
177	T	A	-0.2435
178	F	A	0.0000
179	P	A	-0.4558
180	A	A	0.1329
181	V	A	0.5198
182	L	A	1.1025
183	Q	A	0.1322
184	S	A	-0.1224
185	S	A	-0.2151
186	G	A	0.0679
187	L	A	0.2453
188	Y	A	0.3433
189	S	A	0.0625
190	L	A	0.0000
191	S	A	-0.0685
192	S	A	0.0000
193	V	A	0.0000
194	V	A	0.0000
195	T	A	-0.1452
196	V	A	0.0000
197	P	A	-0.5041
198	S	A	-0.4973
199	S	A	-0.5311
200	S	A	-0.4500
201	L	A	-0.4612
202	G	A	-0.9322
203	T	A	-0.7307
204	Q	A	-1.4429
205	T	A	-1.1337
206	Y	A	-0.9381
207	I	A	-1.2962
208	C	A	0.0000
209	N	A	-1.3434
210	V	A	0.0000
211	N	A	-1.9845
212	H	A	0.0000
213	K	A	-2.8340
214	P	A	-1.5195
215	S	A	-1.6839
216	N	A	-2.5551
217	T	A	-1.8992
218	K	A	-2.3369
219	V	A	-0.8788
220	D	A	-2.2713
221	K	A	-2.0166
222	K	A	-2.5547
223	V	A	0.0000
224	E	A	-2.3199