Project name: 3o2d:H
Status: done
submitted: 2019-03-20 20:01:34, status changed: 2019-03-20 20:12:14
Settings
|
Chain sequence(s)
|
H: QVQLQQSGPEVVKPGASVKMSCKASGYTFTSYVIHWVRQKPGQGLDWIGYINPYNDGTDYDEKFKGKATLTSDTSTSTAYMELSSLRSEDTAVYYCAREKDNYATGAWFAYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVES
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5687
-
Maximal score value
-
2.4883
-
Average score
-
-0.6154
-
Total score value
-
-136.6116
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
H |
-1.4669 |
|
| 2 |
V |
H |
-0.9570 |
|
| 3 |
Q |
H |
-1.5366 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
Q |
H |
-1.6839 |
|
| 6 |
Q |
H |
0.0000 |
|
| 7 |
S |
H |
-0.9877 |
|
| 8 |
G |
H |
-1.0749 |
|
| 9 |
P |
H |
-1.0337 |
|
| 10 |
E |
H |
-1.7363 |
|
| 11 |
V |
H |
-0.9006 |
|
| 12 |
V |
H |
0.0000 |
|
| 13 |
K |
H |
-2.2254 |
|
| 14 |
P |
H |
-2.1193 |
|
| 15 |
G |
H |
-1.4845 |
|
| 16 |
A |
H |
-1.1425 |
|
| 17 |
S |
H |
-1.3800 |
|
| 18 |
V |
H |
0.0000 |
|
| 19 |
K |
H |
-2.2126 |
|
| 20 |
M |
H |
0.0000 |
|
| 21 |
S |
H |
-0.8258 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
K |
H |
-1.6496 |
|
| 24 |
A |
H |
0.0000 |
|
| 25 |
S |
H |
-1.1159 |
|
| 26 |
G |
H |
-0.9808 |
|
| 27 |
Y |
H |
-0.3567 |
|
| 28 |
T |
H |
-0.0741 |
|
| 29 |
F |
H |
0.0000 |
|
| 30 |
T |
H |
0.0570 |
|
| 31 |
S |
H |
0.2634 |
|
| 32 |
Y |
H |
0.1263 |
|
| 33 |
V |
H |
0.1546 |
|
| 34 |
I |
H |
0.0000 |
|
| 35 |
H |
H |
0.0000 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
V |
H |
0.0000 |
|
| 38 |
R |
H |
-0.0999 |
|
| 39 |
Q |
H |
-0.5366 |
|
| 40 |
K |
H |
-1.3297 |
|
| 41 |
P |
H |
-1.1167 |
|
| 42 |
G |
H |
-1.4223 |
|
| 43 |
Q |
H |
-1.6859 |
|
| 44 |
G |
H |
-0.6877 |
|
| 45 |
L |
H |
0.8097 |
|
| 46 |
D |
H |
-0.1654 |
|
| 47 |
W |
H |
0.2562 |
|
| 48 |
I |
H |
0.0000 |
|
| 49 |
G |
H |
0.0000 |
|
| 50 |
Y |
H |
-0.1486 |
|
| 51 |
I |
H |
0.0000 |
|
| 52 |
N |
H |
-0.7836 |
|
| 52A |
P |
H |
0.0000 |
|
| 53 |
Y |
H |
0.1262 |
|
| 54 |
N |
H |
-1.4161 |
|
| 55 |
D |
H |
-1.7266 |
|
| 56 |
G |
H |
-1.2875 |
|
| 57 |
T |
H |
-1.0523 |
|
| 58 |
D |
H |
-1.4170 |
|
| 59 |
Y |
H |
-1.7450 |
|
| 60 |
D |
H |
-2.4075 |
|
| 61 |
E |
H |
-3.5687 |
|
| 62 |
K |
H |
-3.3036 |
|
| 63 |
F |
H |
0.0000 |
|
| 64 |
K |
H |
-3.3154 |
|
| 65 |
G |
H |
-2.0402 |
|
| 66 |
K |
H |
-1.8711 |
|
| 67 |
A |
H |
0.0000 |
|
| 68 |
T |
H |
-1.0094 |
|
| 69 |
L |
H |
0.0000 |
|
| 70 |
T |
H |
-0.7440 |
|
| 71 |
S |
H |
-0.8584 |
|
| 72 |
D |
H |
-0.9390 |
|
| 73 |
T |
H |
-0.6432 |
|
| 74 |
S |
H |
-0.5067 |
|
| 75 |
T |
H |
-0.6347 |
|
| 76 |
S |
H |
-0.6960 |
|
| 77 |
T |
H |
0.0000 |
|
| 78 |
A |
H |
0.0000 |
|
| 79 |
Y |
H |
-0.5808 |
|
| 80 |
M |
H |
0.0000 |
|
| 81 |
E |
H |
-1.6506 |
|
| 82 |
L |
H |
0.0000 |
|
| 82A |
S |
H |
-1.2093 |
|
| 82B |
S |
H |
-1.2202 |
|
| 82C |
L |
H |
0.0000 |
|
| 83 |
R |
H |
-2.9755 |
|
| 84 |
S |
H |
-2.3517 |
|
| 85 |
E |
H |
-2.6631 |
|
| 86 |
D |
H |
-1.8700 |
|
| 87 |
T |
H |
-1.1362 |
|
| 88 |
A |
H |
0.0000 |
|
| 89 |
V |
H |
0.1848 |
|
| 90 |
Y |
H |
0.0000 |
|
| 91 |
Y |
H |
0.1950 |
|
| 92 |
C |
H |
0.0000 |
|
| 93 |
A |
H |
0.0000 |
|
| 94 |
R |
H |
0.0000 |
|
| 95 |
E |
H |
-0.0450 |
|
| 96 |
K |
H |
-0.8839 |
|
| 97 |
D |
H |
-0.6940 |
|
| 98 |
N |
H |
-0.0870 |
|
| 99 |
Y |
H |
1.1217 |
|
| 100 |
A |
H |
0.4683 |
|
| 100A |
T |
H |
0.0813 |
|
| 100B |
G |
H |
0.0000 |
|
| 100C |
A |
H |
0.4847 |
|
| 100D |
W |
H |
1.1047 |
|
| 100E |
F |
H |
0.9970 |
|
| 101 |
A |
H |
0.4197 |
|
| 102 |
Y |
H |
0.4534 |
|
| 103 |
W |
H |
0.2681 |
|
| 104 |
G |
H |
-0.8432 |
|
| 105 |
Q |
H |
-1.2658 |
|
| 106 |
G |
H |
-0.5369 |
|
| 107 |
T |
H |
0.0000 |
|
| 108 |
L |
H |
-0.2897 |
|
| 109 |
V |
H |
0.0000 |
|
| 110 |
T |
H |
0.0000 |
|
| 111 |
V |
H |
0.0000 |
|
| 112 |
S |
H |
-1.0807 |
|
| 113 |
S |
H |
-0.9563 |
|
| 114 |
A |
H |
-0.4837 |
|
| 115 |
S |
H |
-0.5646 |
|
| 116 |
T |
H |
-0.7478 |
|
| 117 |
K |
H |
-0.9999 |
|
| 118 |
G |
H |
-1.3755 |
|
| 119 |
P |
H |
0.0000 |
|
| 120 |
S |
H |
-0.0458 |
|
| 121 |
V |
H |
0.0000 |
|
| 122 |
F |
H |
1.0829 |
|
| 123 |
P |
H |
0.0819 |
|
| 124 |
L |
H |
0.6853 |
|
| 125 |
A |
H |
-0.2526 |
|
| 126 |
P |
H |
-0.4453 |
|
| 127 |
C |
H |
0.2551 |
|
| 128 |
S |
H |
-0.6709 |
|
| 129 |
R |
H |
-1.9806 |
|
| 130 |
S |
H |
-1.3959 |
|
| 131 |
T |
H |
-1.3366 |
|
| 132 |
S |
H |
-1.2313 |
|
| 133 |
E |
H |
-2.3194 |
|
| 134 |
S |
H |
-1.3440 |
|
| 135 |
T |
H |
-0.8962 |
|
| 136 |
A |
H |
-0.7966 |
|
| 137 |
A |
H |
0.0093 |
|
| 138 |
L |
H |
0.0000 |
|
| 139 |
G |
H |
0.0000 |
|
| 140 |
C |
H |
0.0000 |
|
| 141 |
L |
H |
0.7631 |
|
| 142 |
V |
H |
0.0000 |
|
| 143 |
K |
H |
-0.2186 |
|
| 144 |
D |
H |
-0.3406 |
|
| 145 |
Y |
H |
0.0000 |
|
| 146 |
F |
H |
-0.1068 |
|
| 147 |
P |
H |
0.0000 |
|
| 148 |
E |
H |
-0.4450 |
|
| 149 |
P |
H |
-0.7471 |
|
| 150 |
V |
H |
-0.6636 |
|
| 151 |
T |
H |
-0.6335 |
|
| 152 |
V |
H |
-0.4510 |
|
| 153 |
S |
H |
-0.6131 |
|
| 154 |
W |
H |
0.0000 |
|
| 155 |
N |
H |
-1.1156 |
|
| 156 |
S |
H |
-0.8455 |
|
| 157 |
G |
H |
-0.6193 |
|
| 158 |
A |
H |
-0.2809 |
|
| 159 |
L |
H |
-0.1048 |
|
| 160 |
T |
H |
-0.3058 |
|
| 161 |
S |
H |
-0.3613 |
|
| 162 |
G |
H |
-0.4495 |
|
| 163 |
V |
H |
0.0529 |
|
| 164 |
H |
H |
-0.3256 |
|
| 165 |
T |
H |
0.2939 |
|
| 166 |
F |
H |
1.0233 |
|
| 167 |
P |
H |
0.7434 |
|
| 168 |
A |
H |
1.3060 |
|
| 169 |
V |
H |
2.4883 |
|
| 170 |
L |
H |
2.2012 |
|
| 171 |
Q |
H |
0.7271 |
|
| 172 |
S |
H |
0.1021 |
|
| 173 |
S |
H |
-0.2012 |
|
| 174 |
G |
H |
0.2657 |
|
| 175 |
L |
H |
0.4593 |
|
| 176 |
Y |
H |
0.9237 |
|
| 177 |
S |
H |
0.0000 |
|
| 178 |
L |
H |
0.0000 |
|
| 179 |
S |
H |
0.6927 |
|
| 180 |
S |
H |
0.0000 |
|
| 181 |
V |
H |
0.4966 |
|
| 182 |
V |
H |
0.0000 |
|
| 183 |
T |
H |
-0.1955 |
|
| 184 |
V |
H |
0.0000 |
|
| 185 |
P |
H |
-0.6155 |
|
| 186 |
S |
H |
-1.0914 |
|
| 187 |
S |
H |
-0.9880 |
|
| 188 |
S |
H |
0.0000 |
|
| 189 |
L |
H |
-1.3184 |
|
| 190 |
G |
H |
-1.5381 |
|
| 191 |
T |
H |
-1.1165 |
|
| 192 |
K |
H |
-2.0661 |
|
| 193 |
T |
H |
-1.7274 |
|
| 194 |
Y |
H |
0.0000 |
|
| 195 |
T |
H |
-2.0688 |
|
| 196 |
C |
H |
0.0000 |
|
| 197 |
N |
H |
-1.7763 |
|
| 198 |
V |
H |
0.0000 |
|
| 199 |
D |
H |
-2.1020 |
|
| 200 |
H |
H |
0.0000 |
|
| 201 |
K |
H |
-2.9655 |
|
| 202 |
P |
H |
-1.8710 |
|
| 203 |
S |
H |
-1.9213 |
|
| 204 |
N |
H |
-2.6133 |
|
| 205 |
T |
H |
-2.0821 |
|
| 206 |
K |
H |
-2.7519 |
|
| 207 |
V |
H |
-1.6871 |
|
| 208 |
D |
H |
-2.7813 |
|
| 209 |
K |
H |
-2.3626 |
|
| 210 |
R |
H |
-2.8437 |
|
| 211 |
V |
H |
0.0000 |
|
| 212 |
E |
H |
-2.8025 |
|
| 213 |
S |
H |
-1.3922 |
|