Project name: 6b9y:B

Chain sequence(s)	B: EVQLVESGGGLVQPGGSLRLSCAASGFNNIKDTYIHWVRQSPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSSKNTAYLQMNSLRAEDTAIYYCCSRWGGDGFYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPCVVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9164
• Maximal score value: 2.4968
• Average score: -0.5696
• Total score value: -127.0214

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	B	-2.0887
2	V	B	-1.3133
3	Q	B	-1.1325
4	L	B	0.0000
5	V	B	0.3042
6	E	B	0.0000
7	S	B	-0.5286
8	G	B	-0.8509
9	G	B	-0.3754
10	G	B	-0.4017
11	L	B	-0.1124
12	V	B	0.0000
13	Q	B	-1.6631
14	P	B	-1.5284
15	G	B	-1.4407
16	G	B	-1.1428
17	S	B	-1.1319
18	L	B	-1.0991
19	R	B	-1.9388
20	L	B	0.0000
21	S	B	-0.4675
22	C	B	0.0000
23	A	B	-0.2884
24	A	B	0.0000
25	S	B	-1.2020
26	G	B	-1.4059
27	F	B	-1.4982
28	N	B	-2.0042
29	I	B	0.0000
30	K	B	-2.2894
31	D	B	-2.6630
32	T	B	0.0000
33	Y	B	0.0008
34	I	B	0.0000
35	H	B	0.0000
36	W	B	0.0000
37	V	B	0.0000
38	R	B	0.0000
39	Q	B	-0.3150
40	S	B	-1.0060
41	P	B	-1.1997
42	G	B	-1.7909
43	K	B	-2.1494
44	G	B	-0.7885
45	L	B	0.6398
46	E	B	-0.1447
47	W	B	0.1516
48	V	B	0.0000
49	A	B	0.0000
50	R	B	-1.1168
51	I	B	0.0000
52	Y	B	-0.3801
53	P	B	-0.9356
54	T	B	-1.0092
55	N	B	-0.7847
56	G	B	-0.3544
57	Y	B	0.4182
58	T	B	-0.6795
59	R	B	-2.2302
60	Y	B	-2.0308
61	A	B	-1.8316
62	D	B	-2.7007
63	S	B	-1.8339
64	V	B	0.0000
65	K	B	-2.9164
66	G	B	-1.8084
67	R	B	-1.4096
68	F	B	0.0000
69	T	B	-1.1776
70	I	B	0.0000
71	S	B	-0.1795
72	A	B	-0.6438
73	D	B	-1.1358
74	T	B	-1.3587
75	S	B	-1.4248
76	K	B	-2.1376
77	N	B	-1.6264
78	T	B	-0.8599
79	A	B	0.0000
80	Y	B	-0.4330
81	L	B	0.0000
82	Q	B	-1.0935
83	M	B	0.0000
84	N	B	-1.4108
85	S	B	-1.2823
86	L	B	0.0000
87	R	B	-2.4100
88	A	B	-1.7837
89	E	B	-2.6252
90	D	B	0.0000
91	T	B	-0.8332
92	A	B	0.0000
93	I	B	0.5659
94	Y	B	0.0000
95	Y	B	0.3992
96	C	B	0.0000
97	S	B	0.0000
98	R	B	0.0000
99	W	B	0.7016
100	G	B	0.4262
101	G	B	0.0000
102	D	B	-1.5018
103	G	B	-0.2142
104	F	B	1.7695
105	Y	B	1.9220
106	A	B	1.2816
107	M	B	0.9327
108	D	B	0.3181
109	Y	B	0.2228
110	W	B	0.3538
111	G	B	-0.1690
112	Q	B	-0.8477
113	G	B	-0.1811
114	T	B	0.0000
115	L	B	0.3695
116	V	B	0.0000
117	T	B	-0.3930
118	V	B	0.0000
119	S	B	-0.8064
120	S	B	-0.7067
121	A	B	-0.4553
122	S	B	-0.6067
123	T	B	-0.6349
124	K	B	-1.2242
125	G	B	-1.4841
126	P	B	-0.6041
127	S	B	-0.0799
128	V	B	0.0000
129	F	B	1.0227
130	P	B	0.1454
131	L	B	0.3691
132	A	B	-1.0763
133	P	B	0.0000
134	S	B	-1.4012
135	S	B	-1.1807
136	K	B	-1.9208
137	S	B	-1.0194
138	T	B	-1.0118
139	S	B	-0.9509
140	G	B	-0.8562
141	G	B	-0.9176
142	T	B	-0.6320
143	A	B	0.0000
144	A	B	-0.2090
145	L	B	0.0000
146	G	B	0.0000
147	C	B	0.0000
148	L	B	0.7756
149	V	B	0.0000
150	K	B	-0.1632
151	D	B	-0.3927
152	Y	B	0.0000
153	F	B	0.0000
154	P	B	0.0000
155	E	B	-0.2368
156	P	B	-0.5200
157	V	B	-0.6433
158	T	B	-0.5980
159	V	B	-0.1203
160	S	B	-0.3918
161	W	B	0.0000
162	N	B	-0.8102
163	S	B	-0.6642
164	G	B	-0.5695
165	A	B	-0.2464
166	L	B	-0.0329
167	T	B	-0.2942
168	S	B	-0.3620
169	G	B	-0.4732
170	V	B	-0.0192
171	H	B	-0.5252
172	T	B	0.0752
173	F	B	0.8113
174	P	B	0.6844
175	C	B	1.4442
176	V	B	2.4968
177	L	B	2.0863
178	Q	B	0.7435
179	S	B	0.1160
180	S	B	-0.1875
181	G	B	0.2605
182	L	B	0.3702
183	Y	B	0.9626
184	S	B	0.0000
185	L	B	0.0000
186	S	B	0.6533
187	S	B	0.0000
188	V	B	0.3685
189	V	B	0.0000
190	T	B	-0.2369
191	V	B	0.0000
192	P	B	-0.6142
193	S	B	-0.5539
194	S	B	-0.5222
195	S	B	-0.5006
196	L	B	-0.6914
197	G	B	-1.0471
198	T	B	-0.6634
199	Q	B	-1.1798
200	T	B	-1.1308
201	Y	B	0.0000
202	I	B	-1.4412
203	C	B	0.0000
204	N	B	-1.5052
205	V	B	0.0000
206	N	B	-2.1245
207	H	B	0.0000
208	K	B	-2.8075
209	P	B	-1.5838
210	S	B	-1.8625
211	N	B	-2.5944
212	T	B	-2.1570
213	K	B	-2.7938
214	V	B	-1.7197
215	D	B	-2.4065
216	K	B	-2.1258
217	K	B	-2.5337
218	V	B	0.0000
219	E	B	-2.8888
220	P	B	-1.8503
221	K	B	-2.1423
222	S	B	-0.9906
223	C	B	0.2178