Project name: 4qxg:H

Chain sequence(s)	H: EVQLVQSGAEVKKPGESLKISCKGSGYIFTNYWIAWVRQMPGKGLESMGIIYPGDSDIRYSPSFQGQVTISADKSITTAYLQWSSLKASDTAMYYCARHDIEGFDYWGRGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9395
• Maximal score value: 2.5267
• Average score: -0.5396
• Total score value: -117.6226

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1587
2	V	H	-1.0722
3	Q	H	-1.3832
4	L	H	0.0000
5	V	H	0.6082
6	Q	H	-0.1548
7	S	H	-0.5646
8	G	H	-0.3819
9	A	H	-0.2509
10	E	H	-0.5277
11	V	H	-0.0562
12	K	H	-1.2418
13	K	H	-1.7292
14	P	H	-1.6267
15	G	H	-1.6770
16	E	H	-1.9629
17	S	H	-1.6728
18	L	H	0.0000
19	K	H	-1.9754
20	I	H	0.0000
21	S	H	-0.5257
22	C	H	0.0000
23	K	H	-0.7213
24	G	H	0.0000
25	S	H	-0.3763
26	G	H	-0.8559
27	Y	H	0.2674
28	I	H	1.4815
29	F	H	0.0000
30	T	H	-0.6009
31	N	H	-0.7828
32	Y	H	0.1824
33	W	H	0.1154
34	I	H	0.0000
35	A	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.3855
39	Q	H	-0.6882
40	M	H	-0.7898
41	P	H	-1.1024
42	G	H	-1.4033
43	K	H	-2.0910
44	G	H	-1.0204
45	L	H	0.2517
46	E	H	-0.5226
47	S	H	-0.1938
48	M	H	0.0000
49	G	H	0.0000
50	I	H	-0.2834
51	I	H	0.0000
52	Y	H	-1.1900
53	P	H	0.0000
54	G	H	-1.7366
55	D	H	-2.6236
56	S	H	-2.0785
57	D	H	-2.2188
58	I	H	-0.9923
59	R	H	-1.7839
60	Y	H	-0.9564
61	S	H	-0.9012
62	P	H	-0.9885
63	S	H	-0.8520
64	F	H	0.0000
65	Q	H	-1.8474
66	G	H	-1.2697
67	Q	H	-1.0758
68	V	H	0.0000
69	T	H	-0.6285
70	I	H	0.0000
71	S	H	-0.4754
72	A	H	-0.9465
73	D	H	-1.3074
74	K	H	-1.5469
75	S	H	-0.2576
76	I	H	0.9450
77	T	H	-0.0392
78	T	H	0.0000
79	A	H	0.0000
80	Y	H	-0.6735
81	L	H	0.0000
82	Q	H	-1.2657
83	W	H	0.0000
84	S	H	-1.1468
85	S	H	-1.3386
86	L	H	0.0000
87	K	H	-1.3722
88	A	H	-0.6936
89	S	H	-0.3493
90	D	H	0.0000
91	T	H	-0.1935
92	A	H	0.0000
93	M	H	0.1081
94	Y	H	0.0000
95	Y	H	0.0888
96	C	H	0.0000
97	A	H	0.0000
98	R	H	0.0000
99	H	H	-0.2090
100	D	H	-0.3207
101	I	H	0.8040
102	E	H	-1.1737
103	G	H	-0.5507
104	F	H	-0.0135
105	D	H	-0.5366
106	Y	H	0.0993
107	W	H	0.3621
108	G	H	-0.3923
109	R	H	-1.4156
110	G	H	0.0000
111	T	H	0.0000
112	L	H	-0.0524
113	V	H	0.0000
114	T	H	0.0000
115	V	H	0.0000
116	S	H	-0.7154
117	S	H	-0.8398
118	A	H	-0.5376
119	S	H	-0.6164
120	T	H	-0.6029
121	K	H	-1.1702
122	G	H	-1.3651
123	P	H	0.0000
124	S	H	-0.0466
125	V	H	0.0000
126	F	H	0.9949
127	P	H	0.0413
128	L	H	0.2124
129	A	H	-0.8305
130	P	H	0.0000
131	S	H	-1.3072
132	S	H	-1.3716
133	K	H	-1.8834
134	S	H	-1.0245
135	T	H	-0.9999
136	S	H	-0.9250
137	G	H	-0.8855
138	G	H	-0.9227
139	T	H	-0.6386
140	A	H	0.0000
141	A	H	-0.1817
142	L	H	0.0000
143	G	H	0.0000
144	C	H	0.0000
145	L	H	0.7245
146	V	H	0.0000
147	K	H	-0.1802
148	D	H	-0.5874
149	Y	H	0.0000
150	F	H	0.0000
151	P	H	0.0000
152	E	H	-0.3460
153	P	H	-0.6261
154	V	H	-0.5896
155	T	H	-0.4542
156	V	H	-0.1900
157	S	H	-0.4047
158	W	H	0.0000
159	N	H	-0.9057
160	S	H	-0.6961
161	G	H	-0.4693
162	A	H	-0.2150
163	L	H	-0.0476
164	T	H	-0.3375
165	S	H	-0.4132
166	G	H	-0.5520
167	V	H	-0.1615
168	H	H	-0.5610
169	T	H	0.1411
170	F	H	1.0722
171	P	H	0.7871
172	A	H	1.3071
173	V	H	2.5267
174	L	H	2.1659
175	Q	H	0.7437
176	S	H	0.1288
177	S	H	-0.1627
178	G	H	0.2675
179	L	H	0.2837
180	Y	H	0.8264
181	S	H	0.7414
182	L	H	0.0000
183	S	H	0.6626
184	S	H	0.0000
185	V	H	0.3628
186	V	H	0.0000
187	T	H	-0.2936
188	V	H	0.0000
189	P	H	-0.5740
190	S	H	-0.6317
191	S	H	-0.6518
192	S	H	-0.7117
193	L	H	-0.8765
194	G	H	-1.0623
195	T	H	-0.8855
196	Q	H	-1.5394
197	T	H	-1.4151
198	Y	H	0.0000
199	I	H	-1.7180
200	C	H	0.0000
201	N	H	-1.6686
202	V	H	0.0000
203	N	H	-1.7764
204	H	H	0.0000
205	K	H	-2.6740
206	P	H	-1.5540
207	S	H	-1.7964
208	N	H	-2.5419
209	T	H	-2.0497
210	K	H	-2.6673
211	V	H	-1.8379
212	D	H	-2.8308
213	K	H	-2.3036
214	R	H	-2.7863
215	V	H	0.0000
216	E	H	-2.9395
217	P	H	-2.0104
218	K	H	-2.1726