Project name: 243909a126445b1

Chain sequence(s)	H: KRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.1161
• Maximal score value: 2.4915
• Average score: -0.7393
• Total score value: -148.6006

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
151	K	H	-3.0759
152	R	H	-2.9951
153	A	H	-1.5119
154	P	H	0.0000
155	Y	H	0.1148
156	W	H	0.0267
157	T	H	-0.5289
158	N	H	-1.8729
159	T	H	-2.4033
160	E	H	-3.6886
161	K	H	-3.9826
162	M	H	0.0000
163	E	H	-4.1161
164	K	H	-3.7583
165	R	H	-2.8667
166	L	H	-0.4889
167	H	H	-0.7754
168	A	H	0.0144
169	V	H	0.0000
170	P	H	-0.7141
171	A	H	-0.8130
172	A	H	-0.7688
173	N	H	-0.9816
174	T	H	-1.2689
175	V	H	0.0000
176	K	H	-2.0290
177	F	H	0.0000
178	R	H	-1.6653
179	C	H	0.0000
180	P	H	0.0000
181	A	H	0.0000
182	G	H	0.0000
183	G	H	0.0000
184	N	H	-2.3549
185	P	H	-1.5437
186	M	H	-0.2538
187	P	H	0.0000
188	T	H	-0.6681
189	M	H	-1.1774
190	R	H	-2.2182
191	W	H	0.0000
192	L	H	-2.0567
193	K	H	-2.2298
194	N	H	-2.1052
195	G	H	-2.0618
196	K	H	-3.0479
197	E	H	-3.2334
198	F	H	0.0000
199	K	H	-3.2566
200	Q	H	-2.9735
201	E	H	-2.8377
202	H	H	-2.3328
203	R	H	-0.6787
204	I	H	0.9406
205	G	H	-0.4793
206	G	H	0.0000
207	Y	H	-1.1668
208	K	H	-1.9223
209	V	H	-1.8841
210	R	H	-2.9176
211	N	H	-3.0268
212	Q	H	-2.6036
213	H	H	-2.2492
214	W	H	-1.8201
215	S	H	0.0000
216	L	H	0.0000
217	I	H	-1.3224
218	M	H	0.0000
219	E	H	-1.4068
220	S	H	-0.6053
221	V	H	0.0000
222	V	H	0.3392
223	P	H	-0.2008
224	S	H	-0.4038
225	D	H	0.0000
226	K	H	-1.3077
227	G	H	-1.3844
228	N	H	-1.6236
229	Y	H	0.0000
230	T	H	-1.3932
231	C	H	0.0000
232	V	H	-0.9878
233	V	H	0.0000
234	E	H	-1.3367
235	N	H	-1.5706
236	E	H	-2.2875
237	Y	H	-1.2748
238	G	H	-0.7542
239	S	H	-0.6868
240	I	H	-0.2747
241	N	H	-1.2663
242	H	H	-0.9135
243	T	H	-0.9256
244	Y	H	0.0000
245	H	H	-1.2738
246	L	H	0.0000
247	D	H	-0.4561
248	V	H	0.0000
249	V	H	-0.2129
250	E	H	-2.2327
251	R	H	-3.0357
252	S	H	-2.4981
253	P	H	-1.8274
254	H	H	-1.5808
255	R	H	-1.0795
256	P	H	0.0000
257	I	H	1.6510
258	L	H	0.0000
259	Q	H	-0.2490
260	A	H	-0.3049
261	G	H	-0.6986
262	L	H	-0.1744
263	P	H	0.0000
264	A	H	-0.6134
265	N	H	-1.2105
266	A	H	-0.7217
267	S	H	-0.0242
268	T	H	0.4527
269	V	H	1.3789
270	V	H	0.8547
271	G	H	-0.7037
272	G	H	-1.2786
273	D	H	-2.6840
274	V	H	-1.7358
275	E	H	-1.6590
276	F	H	0.0000
277	V	H	-0.0050
278	C	H	0.0000
279	K	H	-0.3019
280	V	H	0.9535
281	Y	H	0.8805
282	S	H	-0.8555
283	D	H	-2.8493
284	A	H	-1.9046
285	Q	H	-1.7609
286	P	H	-0.9360
287	H	H	-1.0058
288	I	H	0.0000
289	Q	H	0.2142
290	W	H	0.0000
291	I	H	0.0000
292	K	H	0.2746
293	H	H	0.5042
294	V	H	1.2785
307	P	H	0.6136
308	Y	H	1.5991
309	L	H	1.2748
310	K	H	0.1318
311	V	H	1.1329
312	L	H	0.7301
313	K	H	0.1120
314	A	H	-0.1491
315	A	H	-1.2391
316	G	H	-0.3505
317	V	H	0.7512
318	N	H	-0.7215
319	T	H	-1.2637
320	T	H	-1.9006
321	D	H	-3.3219
322	K	H	-3.5132
323	E	H	-3.2733
324	I	H	0.0000
325	E	H	-1.5825
326	V	H	-0.7410
327	L	H	0.0000
328	Y	H	0.1750
329	I	H	-1.2352
330	R	H	-3.0680
331	N	H	-2.5606
332	V	H	0.0000
333	T	H	-0.1103
334	F	H	1.0844
335	E	H	-0.9572
336	D	H	-0.8872
337	A	H	0.0838
338	G	H	0.0000
339	E	H	-0.3050
340	Y	H	0.0000
341	T	H	0.0000
342	C	H	0.0000
343	L	H	1.1759
344	A	H	0.0000
345	G	H	0.6174
346	N	H	-0.5980
347	S	H	0.1618
348	I	H	1.1919
349	G	H	0.6747
350	I	H	1.9326
351	S	H	0.0000
352	F	H	2.4915
353	H	H	0.6278
354	S	H	0.0247
355	A	H	0.0000
356	W	H	0.2482
357	L	H	0.0000
358	T	H	0.5166
359	V	H	0.0000
360	L	H	1.7073
361	P	H	0.9395
362	A	H	0.4769
363	P	H	0.0289