| Chain sequence(s) |
A: VLSAADKTNVKAAWSKVGGHAGEYGAEALERMFLGFPTTKTYFPHFDLSHGSAQVKAHGKKVADGLTLAVGHLDDLPGALSDLSNLHAHKLRVDPVNFKLLSHCLLSTLAVHLPNDFTPAVHASLDKFLSSVSTVLTSKYR B: VQLSGEEKAAVLALWDKVNEEEVGGEALGRLLVVYPWTQRFFDSFGDLSNPGAVMGNPKVKAHGKKVLHSFGEGVHHLDNLKGTFAALSELHCDKLHVDPENFRLLGNVLALVVARHFGKDFTPELQASYQKVVAGVANALAHKYH |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | V | A | 1.6066 | |
| 2 | L | A | 0.4482 | |
| 3 | S | A | 0.2255 | |
| 4 | A | A | -0.0670 | |
| 5 | A | A | -0.4081 | |
| 6 | D | A | 0.0000 | |
| 7 | K | A | -1.2444 | |
| 8 | T | A | -0.9537 | |
| 9 | N | A | -0.9542 | |
| 10 | V | A | 0.0000 | |
| 11 | K | A | -1.8987 | |
| 12 | A | A | -1.3360 | |
| 13 | A | A | 0.0000 | |
| 14 | W | A | 0.0000 | |
| 15 | S | A | -1.6537 | |
| 16 | K | A | -2.4346 | |
| 17 | V | A | 0.0000 | |
| 18 | G | A | -1.7193 | |
| 19 | G | A | -1.5828 | |
| 20 | H | A | -2.2934 | |
| 21 | A | A | -2.2233 | |
| 22 | G | A | -2.8564 | |
| 23 | E | A | -2.7686 | |
| 24 | Y | A | 0.0000 | |
| 25 | G | A | 0.0000 | |
| 26 | A | A | 0.0000 | |
| 27 | E | A | -1.1249 | |
| 28 | A | A | 0.0000 | |
| 29 | L | A | 0.0000 | |
| 30 | E | A | -0.6748 | |
| 31 | R | A | 0.0000 | |
| 32 | M | A | 0.0000 | |
| 33 | F | A | 0.0000 | |
| 34 | L | A | 0.0874 | |
| 35 | G | A | -0.1410 | |
| 36 | F | A | 0.0074 | |
| 37 | P | A | -0.3224 | |
| 38 | T | A | -0.2825 | |
| 39 | T | A | 0.0000 | |
| 40 | K | A | -0.7486 | |
| 41 | T | A | -0.4203 | |
| 42 | Y | A | -0.0994 | |
| 43 | F | A | -0.2901 | |
| 44 | P | A | -0.7778 | |
| 45 | H | A | -1.2905 | |
| 46 | F | A | -1.0714 | |
| 47 | D | A | -1.9528 | |
| 48 | L | A | -0.8841 | |
| 49 | S | A | -0.8627 | |
| 50 | H | A | -1.5142 | |
| 51 | G | A | -1.3305 | |
| 52 | S | A | 0.0000 | |
| 53 | A | A | -1.0731 | |
| 54 | Q | A | -1.7053 | |
| 55 | V | A | 0.0000 | |
| 56 | K | A | -2.2529 | |
| 57 | A | A | -1.5415 | |
| 58 | H | A | -1.5600 | |
| 59 | G | A | 0.0000 | |
| 60 | K | A | -3.6943 | |
| 61 | K | A | -3.1307 | |
| 62 | V | A | -1.7719 | |
| 63 | A | A | 0.0000 | |
| 64 | D | A | -2.4233 | |
| 65 | G | A | -0.9772 | |
| 66 | L | A | -0.1491 | |
| 67 | T | A | -0.0608 | |
| 68 | L | A | 0.8461 | |
| 69 | A | A | 0.0000 | |
| 70 | V | A | -0.4065 | |
| 71 | G | A | -0.9271 | |
| 72 | H | A | -1.7255 | |
| 73 | L | A | -1.7474 | |
| 74 | D | A | -3.0337 | |
| 75 | D | A | -3.1332 | |
| 76 | L | A | 0.0000 | |
| 77 | P | A | -1.6075 | |
| 78 | G | A | -1.6432 | |
| 79 | A | A | -1.1767 | |
| 80 | L | A | 0.0000 | |
| 81 | S | A | -1.5278 | |
| 82 | D | A | -2.0960 | |
| 83 | L | A | -0.7413 | |
| 84 | S | A | 0.0000 | |
| 85 | N | A | -2.6071 | |
| 86 | L | A | -1.5554 | |
| 87 | H | A | -1.7445 | |
| 88 | A | A | -2.6194 | |
| 89 | H | A | -2.4741 | |
| 90 | K | A | -2.3838 | |
| 91 | L | A | -1.1495 | |
| 92 | R | A | -2.5781 | |
| 93 | V | A | -1.2088 | |
| 94 | D | A | -1.5021 | |
| 95 | P | A | -0.6200 | |
| 96 | V | A | 0.7389 | |
| 97 | N | A | 0.0000 | |
| 98 | F | A | -0.2320 | |
| 99 | K | A | -1.0437 | |
| 100 | L | A | -0.0916 | |
| 101 | L | A | 0.1298 | |
| 102 | S | A | 0.0000 | |
| 103 | H | A | -0.4807 | |
| 104 | C | A | 0.0000 | |
| 105 | L | A | 0.0000 | |
| 106 | L | A | 0.0000 | |
| 107 | S | A | 0.0000 | |
| 108 | T | A | 0.0000 | |
| 109 | L | A | 0.0000 | |
| 110 | A | A | 0.0000 | |
| 111 | V | A | 0.0000 | |
| 112 | H | A | -1.4964 | |
| 113 | L | A | 0.0000 | |
| 114 | P | A | -1.1899 | |
| 115 | N | A | -1.6779 | |
| 116 | D | A | -1.4686 | |
| 117 | F | A | 0.0000 | |
| 118 | T | A | -0.6087 | |
| 119 | P | A | -0.1340 | |
| 120 | A | A | -0.2787 | |
| 121 | V | A | 0.0000 | |
| 122 | H | A | 0.0000 | |
| 123 | A | A | -0.3547 | |
| 124 | S | A | 0.0000 | |
| 125 | L | A | 0.0000 | |
| 126 | D | A | -0.9779 | |
| 127 | K | A | -0.8676 | |
| 128 | F | A | 0.0000 | |
| 129 | L | A | 0.0000 | |
| 130 | S | A | -0.8569 | |
| 131 | S | A | -0.0907 | |
| 132 | V | A | 0.0000 | |
| 133 | S | A | -0.2298 | |
| 134 | T | A | -0.2447 | |
| 135 | V | A | -0.3617 | |
| 136 | L | A | -0.4691 | |
| 137 | T | A | -1.0060 | |
| 138 | S | A | -1.3087 | |
| 139 | K | A | -2.2169 | |
| 140 | Y | A | -2.1987 | |
| 141 | R | A | -2.1177 | |
| 1 | V | B | 1.0999 | |
| 2 | Q | B | -0.6104 | |
| 3 | L | B | -0.8090 | |
| 4 | S | B | -1.4408 | |
| 5 | G | B | -1.9261 | |
| 6 | E | B | -2.5928 | |
| 7 | E | B | -2.0837 | |
| 8 | K | B | -2.0126 | |
| 9 | A | B | -1.2066 | |
| 10 | A | B | -1.2136 | |
| 11 | V | B | 0.0000 | |
| 12 | L | B | -1.1286 | |
| 13 | A | B | -0.8981 | |
| 14 | L | B | 0.0000 | |
| 15 | W | B | 0.0000 | |
| 16 | D | B | -2.7948 | |
| 17 | K | B | -3.0389 | |
| 18 | V | B | 0.0000 | |
| 19 | N | B | -3.1319 | |
| 20 | E | B | -3.3436 | |
| 21 | E | B | -3.5078 | |
| 22 | E | B | -3.1264 | |
| 23 | V | B | 0.0000 | |
| 24 | G | B | 0.0000 | |
| 25 | G | B | 0.0000 | |
| 26 | E | B | 0.0000 | |
| 27 | A | B | 0.0000 | |
| 28 | L | B | 0.0000 | |
| 29 | G | B | 0.0000 | |
| 30 | R | B | 0.0000 | |
| 31 | L | B | 0.0000 | |
| 32 | L | B | 0.0000 | |
| 33 | V | B | -0.0204 | |
| 34 | V | B | 0.0000 | |
| 35 | Y | B | 0.0000 | |
| 36 | P | B | 0.0673 | |
| 37 | W | B | 0.6120 | |
| 38 | T | B | 0.0000 | |
| 39 | Q | B | -1.1532 | |
| 40 | R | B | -1.6405 | |
| 41 | F | B | -0.5355 | |
| 42 | F | B | 0.0000 | |
| 43 | D | B | -2.4444 | |
| 44 | S | B | -1.3173 | |
| 45 | F | B | -1.4783 | |
| 46 | G | B | -2.0831 | |
| 47 | D | B | -2.7124 | |
| 48 | L | B | -1.6802 | |
| 49 | S | B | -1.4141 | |
| 50 | N | B | -1.7760 | |
| 51 | P | B | -1.1186 | |
| 52 | G | B | -0.9432 | |
| 53 | A | B | -1.2582 | |
| 54 | V | B | 0.0000 | |
| 55 | M | B | -1.1076 | |
| 56 | G | B | -1.2976 | |
| 57 | N | B | -1.5522 | |
| 58 | P | B | -1.6188 | |
| 59 | K | B | -2.5839 | |
| 60 | V | B | 0.0000 | |
| 61 | K | B | -2.7971 | |
| 62 | A | B | -2.1760 | |
| 63 | H | B | -1.8256 | |
| 64 | G | B | 0.0000 | |
| 65 | K | B | -3.3080 | |
| 66 | K | B | -2.7693 | |
| 67 | V | B | -1.0357 | |
| 68 | L | B | 0.0000 | |
| 69 | H | B | -2.3636 | |
| 70 | S | B | -1.4392 | |
| 71 | F | B | -1.1854 | |
| 72 | G | B | 0.0000 | |
| 73 | E | B | -2.5130 | |
| 74 | G | B | 0.0000 | |
| 75 | V | B | 0.0000 | |
| 76 | H | B | -2.2254 | |
| 77 | H | B | -2.7639 | |
| 78 | L | B | -2.2386 | |
| 79 | D | B | -3.0978 | |
| 80 | N | B | -2.9052 | |
| 81 | L | B | 0.0000 | |
| 82 | K | B | -2.8809 | |
| 83 | G | B | -1.9656 | |
| 84 | T | B | -1.5237 | |
| 85 | F | B | 0.0000 | |
| 86 | A | B | -1.2479 | |
| 87 | A | B | -0.6600 | |
| 88 | L | B | -0.3095 | |
| 89 | S | B | 0.0000 | |
| 90 | E | B | -2.3981 | |
| 91 | L | B | -1.1847 | |
| 92 | H | B | -1.4542 | |
| 93 | C | B | -2.3474 | |
| 94 | D | B | -3.0902 | |
| 95 | K | B | -2.6378 | |
| 96 | L | B | -1.4368 | |
| 97 | H | B | -1.7531 | |
| 98 | V | B | -1.7984 | |
| 99 | D | B | -2.5926 | |
| 100 | P | B | -2.2026 | |
| 101 | E | B | -2.7896 | |
| 102 | N | B | -1.6452 | |
| 103 | F | B | -1.3530 | |
| 104 | R | B | -2.0035 | |
| 105 | L | B | -1.0739 | |
| 106 | L | B | -0.3450 | |
| 107 | G | B | 0.0000 | |
| 108 | N | B | -0.5397 | |
| 109 | V | B | 0.0000 | |
| 110 | L | B | 0.0000 | |
| 111 | A | B | 0.0000 | |
| 112 | L | B | 0.0000 | |
| 113 | V | B | 0.0000 | |
| 114 | V | B | 0.0000 | |
| 115 | A | B | 0.0000 | |
| 116 | R | B | -1.2543 | |
| 117 | H | B | -1.2112 | |
| 118 | F | B | -1.2298 | |
| 119 | G | B | 0.0000 | |
| 120 | K | B | -2.7072 | |
| 121 | D | B | -2.5970 | |
| 122 | F | B | 0.0000 | |
| 123 | T | B | -1.4264 | |
| 124 | P | B | -1.2902 | |
| 125 | E | B | -1.7071 | |
| 126 | L | B | -1.0655 | |
| 127 | Q | B | 0.0000 | |
| 128 | A | B | -0.5815 | |
| 129 | S | B | 0.0000 | |
| 130 | Y | B | 0.0000 | |
| 131 | Q | B | -0.4610 | |
| 132 | K | B | -0.5407 | |
| 133 | V | B | 0.0000 | |
| 134 | V | B | 0.0000 | |
| 135 | A | B | -0.7189 | |
| 136 | G | B | -0.8722 | |
| 137 | V | B | 0.0000 | |
| 138 | A | B | 0.0000 | |
| 139 | N | B | -1.3141 | |
| 140 | A | B | 0.0000 | |
| 141 | L | B | -1.0060 | |
| 142 | A | B | -1.6988 | |
| 143 | H | B | -2.1188 | |
| 144 | K | B | -2.7032 | |
| 145 | Y | B | -1.5971 | |
| 146 | H | B | -1.6990 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine