Project name: 24fe75be5fa2f66

Chain sequence(s)	A: LIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMMENQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0478
• Maximal score value: 1.6381
• Average score: -1.1106
• Total score value: -174.3642

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	L	A	1.6381
2	I	A	1.3083
3	V	A	0.0000
4	T	A	0.1167
5	Q	A	-0.9916
6	T	A	-0.8745
7	M	A	-1.2663
8	K	A	-2.0515
9	G	A	-1.4920
10	L	A	0.0000
11	D	A	-1.6403
12	I	A	-1.5123
13	Q	A	-2.0275
14	K	A	-2.5922
15	V	A	0.0000
16	A	A	-1.4973
17	G	A	-1.2592
18	T	A	-0.9365
19	W	A	0.0000
20	Y	A	-0.8091
21	S	A	0.0000
22	L	A	0.0000
23	A	A	0.0000
24	M	A	0.0000
25	A	A	0.0000
26	A	A	0.0000
27	S	A	0.0000
28	D	A	-1.4661
29	I	A	0.1700
30	S	A	-0.3091
31	L	A	-0.3104
32	L	A	0.0000
33	D	A	-1.6329
34	A	A	-1.0064
35	Q	A	-1.6715
36	S	A	-1.8578
37	A	A	0.0000
38	P	A	-0.6963
39	L	A	-0.2155
40	R	A	-0.6146
41	V	A	0.0000
42	Y	A	0.0000
43	V	A	0.0000
44	E	A	-1.8470
45	E	A	-2.0529
46	L	A	0.0000
47	K	A	-2.1025
48	P	A	0.0000
49	T	A	-1.5849
50	P	A	-1.4687
51	E	A	-2.5042
52	G	A	-2.3763
53	D	A	-2.5854
54	L	A	0.0000
55	E	A	-1.7363
56	I	A	0.0000
57	L	A	-1.8333
58	L	A	0.0000
59	Q	A	-1.6605
60	K	A	0.0000
61	W	A	-2.3041
62	E	A	-3.3094
63	N	A	-2.9373
64	G	A	-2.5356
65	E	A	-3.1090
66	C	A	-1.9594
67	A	A	-2.0736
68	Q	A	-2.5738
69	K	A	-2.3048
70	K	A	-2.3542
71	I	A	-0.7781
72	I	A	-0.7447
73	A	A	0.0000
74	E	A	-3.3339
75	K	A	-3.1000
76	T	A	-2.0442
77	K	A	-1.6686
78	I	A	-0.5348
79	P	A	-0.9898
80	A	A	0.0000
81	V	A	0.0000
82	F	A	0.0000
83	K	A	-2.6964
84	I	A	-2.1202
85	D	A	-2.5801
86	A	A	-1.2588
87	L	A	0.0630
88	N	A	-2.0629
89	E	A	-3.2628
90	N	A	-2.4557
91	K	A	-2.0083
92	V	A	0.0000
93	L	A	0.0000
94	V	A	0.0000
95	L	A	0.0000
96	D	A	-1.0088
97	T	A	0.0000
98	D	A	-1.2756
99	Y	A	-1.6779
100	K	A	-2.3569
101	K	A	-1.7028
102	Y	A	0.0000
103	L	A	0.0000
104	L	A	0.0000
105	F	A	0.0000
106	C	A	0.0000
107	M	A	-0.3714
108	E	A	0.0000
109	N	A	-2.0160
115	Q	A	-1.3505
116	S	A	-1.1117
117	L	A	0.0000
118	A	A	0.0000
119	C	A	0.0000
120	Q	A	0.0000
121	C	A	0.0000
122	L	A	0.0000
123	V	A	0.0000
124	R	A	-1.3020
125	T	A	-1.1088
126	P	A	-1.3562
127	E	A	-1.6959
128	V	A	-0.5715
129	D	A	-1.8136
130	D	A	-3.0981
131	E	A	-3.4349
132	A	A	0.0000
133	L	A	-2.5002
134	E	A	-4.0478
135	K	A	-3.2603
136	F	A	0.0000
137	D	A	-3.4595
138	K	A	-3.4266
139	A	A	-2.2396
140	L	A	0.0000
141	K	A	-2.4183
142	A	A	-1.1319
143	L	A	-0.6524
144	P	A	-0.6915
145	M	A	-1.0905
146	H	A	-1.3107
147	I	A	0.0000
148	R	A	-2.1212
149	L	A	-0.9301
150	S	A	-0.4843
151	F	A	0.0000
152	N	A	-1.3449
153	P	A	-1.5410
154	T	A	-1.3649
155	Q	A	-1.3749
156	L	A	0.0000
157	E	A	-2.7653
158	E	A	-2.4243
159	Q	A	-2.2162
160	C	A	0.0000
161	H	A	-0.7838
162	I	A	0.7559