Project name: 6ani:H
Status: done
submitted: 2019-03-20 16:17:03, status changed: 2019-03-20 17:32:53
Settings
|
Chain sequence(s)
|
H: QVQLVQPGAEVVKPGASVKLSCKTSGYTFTSNWMHWVKQAPGQGLEWIGEIDPSDSYTNYNQNFQGKAKLTVDKSTSTAYMEVSSLRSDDTAVYYCARGSNPYYYAMDYWGQGTSVTVSSASTKGPSVFPLAPSSKGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.0112
-
Maximal score value
-
2.2213
-
Average score
-
-0.5531
-
Total score value
-
-119.4737
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
H |
-1.4458 |
|
| 2 |
V |
H |
-1.0017 |
|
| 3 |
Q |
H |
-1.5438 |
|
| 4 |
L |
H |
0.0000 |
|
| 5 |
V |
H |
-0.5740 |
|
| 6 |
Q |
H |
0.0000 |
|
| 7 |
P |
H |
-0.7360 |
|
| 8 |
G |
H |
-0.8032 |
|
| 9 |
A |
H |
-0.3561 |
|
| 10 |
E |
H |
-0.3333 |
|
| 11 |
V |
H |
0.4069 |
|
| 12 |
V |
H |
-0.5984 |
|
| 13 |
K |
H |
-1.9460 |
|
| 14 |
P |
H |
-1.7990 |
|
| 15 |
G |
H |
-1.5395 |
|
| 16 |
A |
H |
-1.0949 |
|
| 17 |
S |
H |
-1.3773 |
|
| 18 |
V |
H |
0.0000 |
|
| 19 |
K |
H |
-2.4188 |
|
| 20 |
L |
H |
0.0000 |
|
| 21 |
S |
H |
-0.8005 |
|
| 22 |
C |
H |
0.0000 |
|
| 23 |
K |
H |
-1.2574 |
|
| 24 |
T |
H |
0.0000 |
|
| 25 |
S |
H |
-1.0163 |
|
| 26 |
G |
H |
-0.9878 |
|
| 27 |
Y |
H |
-0.4133 |
|
| 28 |
T |
H |
-0.3155 |
|
| 29 |
F |
H |
0.0000 |
|
| 30 |
T |
H |
-0.7732 |
|
| 31 |
S |
H |
-0.4106 |
|
| 32 |
N |
H |
0.0000 |
|
| 33 |
W |
H |
0.0533 |
|
| 34 |
M |
H |
0.0000 |
|
| 35 |
H |
H |
0.0000 |
|
| 36 |
W |
H |
0.0000 |
|
| 37 |
V |
H |
0.0000 |
|
| 38 |
K |
H |
-0.2481 |
|
| 39 |
Q |
H |
-0.4993 |
|
| 40 |
A |
H |
-1.0243 |
|
| 41 |
P |
H |
-0.9922 |
|
| 42 |
G |
H |
-1.3236 |
|
| 43 |
Q |
H |
-1.6337 |
|
| 44 |
G |
H |
-0.8011 |
|
| 45 |
L |
H |
0.5204 |
|
| 46 |
E |
H |
-0.5327 |
|
| 47 |
W |
H |
0.0318 |
|
| 48 |
I |
H |
0.0000 |
|
| 49 |
G |
H |
0.0000 |
|
| 50 |
E |
H |
0.0000 |
|
| 51 |
I |
H |
0.0000 |
|
| 52 |
D |
H |
-0.4638 |
|
| 52A |
P |
H |
0.0000 |
|
| 53 |
S |
H |
-1.2491 |
|
| 54 |
D |
H |
-1.6120 |
|
| 55 |
S |
H |
-0.8251 |
|
| 56 |
Y |
H |
0.3525 |
|
| 57 |
T |
H |
-0.2452 |
|
| 58 |
N |
H |
-0.6605 |
|
| 59 |
Y |
H |
-1.1778 |
|
| 60 |
N |
H |
-1.4511 |
|
| 61 |
Q |
H |
-2.3481 |
|
| 62 |
N |
H |
-2.2020 |
|
| 63 |
F |
H |
-1.8325 |
|
| 64 |
Q |
H |
-2.4298 |
|
| 65 |
G |
H |
-1.9497 |
|
| 66 |
K |
H |
-1.8230 |
|
| 67 |
A |
H |
0.0000 |
|
| 68 |
K |
H |
-2.4686 |
|
| 69 |
L |
H |
0.0000 |
|
| 70 |
T |
H |
-0.7541 |
|
| 71 |
V |
H |
-0.9066 |
|
| 72 |
D |
H |
-1.4468 |
|
| 73 |
K |
H |
-2.0960 |
|
| 74 |
S |
H |
-1.2122 |
|
| 75 |
T |
H |
-1.0803 |
|
| 76 |
S |
H |
-1.2591 |
|
| 77 |
T |
H |
0.0000 |
|
| 78 |
A |
H |
0.0000 |
|
| 79 |
Y |
H |
-0.9208 |
|
| 80 |
M |
H |
0.0000 |
|
| 81 |
E |
H |
-2.4405 |
|
| 82 |
V |
H |
0.0000 |
|
| 82A |
S |
H |
-1.4918 |
|
| 82B |
S |
H |
-1.2310 |
|
| 82C |
L |
H |
0.0000 |
|
| 83 |
R |
H |
-3.0112 |
|
| 84 |
S |
H |
-2.2518 |
|
| 85 |
D |
H |
-2.4985 |
|
| 86 |
D |
H |
0.0000 |
|
| 87 |
T |
H |
-0.9237 |
|
| 88 |
A |
H |
0.0000 |
|
| 89 |
V |
H |
0.1046 |
|
| 90 |
Y |
H |
0.0000 |
|
| 91 |
Y |
H |
0.2963 |
|
| 92 |
C |
H |
0.0000 |
|
| 93 |
A |
H |
0.0000 |
|
| 94 |
R |
H |
-0.1735 |
|
| 95 |
G |
H |
0.0000 |
|
| 96 |
S |
H |
0.2068 |
|
| 97 |
N |
H |
-0.5976 |
|
| 98 |
P |
H |
0.2857 |
|
| 99 |
Y |
H |
1.3243 |
|
| 100 |
Y |
H |
2.1393 |
|
| 100A |
Y |
H |
1.8174 |
|
| 100B |
A |
H |
1.0915 |
|
| 100C |
M |
H |
0.5510 |
|
| 101 |
D |
H |
-0.2632 |
|
| 102 |
Y |
H |
-0.0982 |
|
| 103 |
W |
H |
0.2272 |
|
| 104 |
G |
H |
0.0000 |
|
| 105 |
Q |
H |
-1.0731 |
|
| 106 |
G |
H |
0.0000 |
|
| 107 |
T |
H |
0.0000 |
|
| 108 |
S |
H |
-0.2508 |
|
| 109 |
V |
H |
0.0000 |
|
| 110 |
T |
H |
-0.5125 |
|
| 111 |
V |
H |
0.0000 |
|
| 112 |
S |
H |
-0.7564 |
|
| 113 |
S |
H |
-0.6959 |
|
| 114 |
A |
H |
-0.4582 |
|
| 115 |
S |
H |
-0.5123 |
|
| 116 |
T |
H |
-0.7370 |
|
| 117 |
K |
H |
-1.1865 |
|
| 118 |
G |
H |
-1.4216 |
|
| 119 |
P |
H |
0.0000 |
|
| 120 |
S |
H |
0.0188 |
|
| 121 |
V |
H |
0.0000 |
|
| 122 |
F |
H |
1.0072 |
|
| 123 |
P |
H |
0.0679 |
|
| 124 |
L |
H |
0.3607 |
|
| 125 |
A |
H |
-0.4822 |
|
| 126 |
P |
H |
0.0000 |
|
| 127 |
S |
H |
-0.9844 |
|
| 128 |
S |
H |
-1.1889 |
|
| 129 |
K |
H |
-1.9451 |
|
| 134 |
G |
H |
-0.8557 |
|
| 135 |
T |
H |
-0.6390 |
|
| 136 |
A |
H |
-0.5378 |
|
| 137 |
A |
H |
0.1175 |
|
| 138 |
L |
H |
0.0000 |
|
| 139 |
G |
H |
0.0000 |
|
| 140 |
C |
H |
0.0000 |
|
| 141 |
L |
H |
0.7767 |
|
| 142 |
V |
H |
0.0000 |
|
| 143 |
K |
H |
-0.0983 |
|
| 144 |
D |
H |
-0.3890 |
|
| 145 |
Y |
H |
0.0000 |
|
| 146 |
F |
H |
0.0000 |
|
| 147 |
P |
H |
-0.7763 |
|
| 148 |
E |
H |
-0.9843 |
|
| 149 |
P |
H |
-1.1003 |
|
| 150 |
V |
H |
-0.8136 |
|
| 151 |
T |
H |
-0.6205 |
|
| 152 |
V |
H |
-0.1165 |
|
| 153 |
S |
H |
-0.4041 |
|
| 154 |
W |
H |
0.0000 |
|
| 155 |
N |
H |
-0.8362 |
|
| 156 |
S |
H |
-0.6846 |
|
| 157 |
G |
H |
-0.5406 |
|
| 158 |
A |
H |
-0.2636 |
|
| 159 |
L |
H |
-0.0463 |
|
| 160 |
T |
H |
-0.2985 |
|
| 161 |
S |
H |
-0.3654 |
|
| 162 |
G |
H |
-0.4442 |
|
| 163 |
V |
H |
0.0985 |
|
| 164 |
H |
H |
-0.3514 |
|
| 165 |
T |
H |
0.3156 |
|
| 166 |
F |
H |
1.1356 |
|
| 167 |
P |
H |
0.7249 |
|
| 168 |
A |
H |
1.0749 |
|
| 169 |
V |
H |
2.2213 |
|
| 170 |
L |
H |
1.5346 |
|
| 171 |
Q |
H |
0.2429 |
|
| 172 |
S |
H |
-0.1189 |
|
| 173 |
S |
H |
-0.3274 |
|
| 174 |
G |
H |
0.0373 |
|
| 175 |
L |
H |
0.0587 |
|
| 176 |
Y |
H |
0.5911 |
|
| 177 |
S |
H |
0.0000 |
|
| 178 |
L |
H |
0.0000 |
|
| 179 |
S |
H |
0.7563 |
|
| 180 |
S |
H |
0.0000 |
|
| 181 |
V |
H |
0.5476 |
|
| 182 |
V |
H |
0.0000 |
|
| 183 |
T |
H |
-0.1891 |
|
| 184 |
V |
H |
0.0000 |
|
| 185 |
P |
H |
-0.5501 |
|
| 186 |
S |
H |
-0.6905 |
|
| 187 |
S |
H |
-0.5689 |
|
| 188 |
S |
H |
-0.5688 |
|
| 189 |
L |
H |
-0.7133 |
|
| 190 |
G |
H |
-0.9296 |
|
| 191 |
T |
H |
-0.7127 |
|
| 192 |
Q |
H |
-1.2311 |
|
| 193 |
T |
H |
-1.1771 |
|
| 194 |
Y |
H |
0.0000 |
|
| 195 |
I |
H |
-1.5179 |
|
| 196 |
C |
H |
0.0000 |
|
| 197 |
N |
H |
-1.5784 |
|
| 198 |
V |
H |
0.0000 |
|
| 199 |
N |
H |
-1.9999 |
|
| 200 |
H |
H |
0.0000 |
|
| 201 |
K |
H |
-2.8142 |
|
| 202 |
P |
H |
-1.7007 |
|
| 203 |
S |
H |
-1.8488 |
|
| 204 |
N |
H |
-2.5556 |
|
| 205 |
T |
H |
-2.0880 |
|
| 206 |
K |
H |
-2.7362 |
|
| 207 |
V |
H |
-1.7103 |
|
| 208 |
D |
H |
-2.7001 |
|
| 209 |
K |
H |
-2.0404 |
|
| 210 |
K |
H |
-2.5453 |
|
| 211 |
V |
H |
0.0000 |
|
| 212 |
E |
H |
-2.4312 |
|
| 213 |
P |
H |
-1.1626 |
|