Project name: 6au5:A
Status: done
submitted: 2019-03-20 20:41:21, status changed: 2019-03-20 20:53:17
Settings
|
Chain sequence(s)
|
A: DILLTQSPVILSVSPGERVSFSCRASQSIGTNIHWYQQRTNGSPRLLIKYASESISGIPSRFSGSGSGTDFTLSINSVESEDIADYYCQQNNNWPTTFGAGTKLELKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.6762
-
Maximal score value
-
1.8561
-
Average score
-
-0.8154
-
Total score value
-
-172.86
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
A |
-1.3168 |
|
| 2 |
I |
A |
0.0000 |
|
| 3 |
L |
A |
0.7819 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.2794 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
0.0422 |
|
| 8 |
P |
A |
0.8307 |
|
| 9 |
V |
A |
1.8561 |
|
| 10 |
I |
A |
1.4359 |
|
| 11 |
L |
A |
0.6343 |
|
| 12 |
S |
A |
-0.2741 |
|
| 13 |
V |
A |
-1.0547 |
|
| 14 |
S |
A |
-1.7113 |
|
| 15 |
P |
A |
-1.8956 |
|
| 16 |
G |
A |
-2.1442 |
|
| 17 |
E |
A |
-2.9060 |
|
| 18 |
R |
A |
-3.3341 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
S |
A |
-0.7909 |
|
| 21 |
F |
A |
0.0000 |
|
| 22 |
S |
A |
-0.8757 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.6130 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-0.9587 |
|
| 27 |
Q |
A |
-1.2617 |
|
| 28 |
S |
A |
-1.5040 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-1.0524 |
|
| 31 |
T |
A |
-0.7397 |
|
| 32 |
N |
A |
-0.9459 |
|
| 33 |
I |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.0197 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.4005 |
|
| 39 |
R |
A |
-1.8919 |
|
| 40 |
T |
A |
-1.7712 |
|
| 41 |
N |
A |
-1.8966 |
|
| 42 |
G |
A |
-1.4348 |
|
| 43 |
S |
A |
-1.0071 |
|
| 44 |
P |
A |
-0.9294 |
|
| 45 |
R |
A |
-0.6675 |
|
| 46 |
L |
A |
-0.0460 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.6731 |
|
| 50 |
Y |
A |
-0.0938 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-1.1219 |
|
| 53 |
E |
A |
-1.8618 |
|
| 54 |
S |
A |
-1.0741 |
|
| 55 |
I |
A |
-0.4791 |
|
| 56 |
S |
A |
-0.2468 |
|
| 57 |
G |
A |
-0.3974 |
|
| 58 |
I |
A |
-0.1207 |
|
| 59 |
P |
A |
-0.2680 |
|
| 60 |
S |
A |
-0.5562 |
|
| 61 |
R |
A |
-1.1292 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.9276 |
|
| 64 |
G |
A |
-0.6689 |
|
| 65 |
S |
A |
-0.8191 |
|
| 66 |
G |
A |
-1.1398 |
|
| 67 |
S |
A |
-1.1741 |
|
| 68 |
G |
A |
-1.4254 |
|
| 69 |
T |
A |
-2.0405 |
|
| 70 |
D |
A |
-2.8678 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.9546 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
S |
A |
-0.9647 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.7099 |
|
| 77 |
S |
A |
-2.3785 |
|
| 78 |
V |
A |
0.0000 |
|
| 79 |
E |
A |
-2.5624 |
|
| 80 |
S |
A |
-2.3477 |
|
| 81 |
E |
A |
-2.1859 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
I |
A |
0.0000 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
D |
A |
-0.9045 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.1390 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
Q |
A |
0.2751 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
N |
A |
-1.4923 |
|
| 92 |
N |
A |
-1.7391 |
|
| 93 |
N |
A |
-1.2864 |
|
| 94 |
W |
A |
-0.0079 |
|
| 95 |
P |
A |
-0.1856 |
|
| 96 |
T |
A |
-0.5091 |
|
| 97 |
T |
A |
0.2544 |
|
| 98 |
F |
A |
1.4052 |
|
| 99 |
G |
A |
0.6490 |
|
| 100 |
A |
A |
0.6217 |
|
| 101 |
G |
A |
0.0000 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-0.3692 |
|
| 104 |
L |
A |
0.0000 |
|
| 105 |
E |
A |
-0.8641 |
|
| 106 |
L |
A |
0.0000 |
|
| 107 |
K |
A |
-1.6218 |
|
| 108 |
R |
A |
-1.1642 |
|
| 109 |
T |
A |
-0.1618 |
|
| 110 |
V |
A |
0.2417 |
|
| 111 |
A |
A |
0.0016 |
|
| 112 |
A |
A |
-0.2408 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.1316 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.0931 |
|
| 117 |
I |
A |
1.1523 |
|
| 118 |
F |
A |
1.3688 |
|
| 119 |
P |
A |
-0.0731 |
|
| 120 |
P |
A |
-0.7541 |
|
| 121 |
S |
A |
-1.8154 |
|
| 122 |
D |
A |
-3.2253 |
|
| 123 |
E |
A |
-3.4179 |
|
| 124 |
Q |
A |
-2.4916 |
|
| 125 |
L |
A |
-2.5468 |
|
| 126 |
K |
A |
-3.0069 |
|
| 127 |
S |
A |
-1.8920 |
|
| 128 |
G |
A |
-1.3762 |
|
| 129 |
T |
A |
-1.2035 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0242 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.7024 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.4603 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.6241 |
|
| 138 |
N |
A |
-1.3697 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.8412 |
|
| 142 |
R |
A |
-2.9764 |
|
| 143 |
E |
A |
-3.1231 |
|
| 144 |
A |
A |
-2.0122 |
|
| 145 |
K |
A |
-1.6142 |
|
| 146 |
V |
A |
-1.0281 |
|
| 147 |
Q |
A |
-0.9432 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.8442 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-2.0597 |
|
| 152 |
N |
A |
-1.5867 |
|
| 153 |
A |
A |
-0.3219 |
|
| 154 |
L |
A |
0.6186 |
|
| 155 |
Q |
A |
-0.1829 |
|
| 156 |
S |
A |
-0.4611 |
|
| 157 |
G |
A |
-1.0213 |
|
| 158 |
N |
A |
-0.9981 |
|
| 159 |
S |
A |
-1.4520 |
|
| 160 |
Q |
A |
-2.2680 |
|
| 161 |
E |
A |
-2.2600 |
|
| 162 |
S |
A |
-1.2931 |
|
| 163 |
V |
A |
-0.7783 |
|
| 164 |
T |
A |
-1.2575 |
|
| 165 |
E |
A |
-2.4361 |
|
| 166 |
Q |
A |
0.0000 |
|
| 167 |
D |
A |
-2.3762 |
|
| 168 |
S |
A |
-2.4484 |
|
| 169 |
K |
A |
-2.8083 |
|
| 170 |
D |
A |
-2.1807 |
|
| 171 |
S |
A |
0.0000 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-1.0238 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4585 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.5714 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.4022 |
|
| 181 |
L |
A |
-0.7640 |
|
| 182 |
S |
A |
-1.1541 |
|
| 183 |
K |
A |
-2.1918 |
|
| 184 |
A |
A |
-2.0250 |
|
| 185 |
D |
A |
-2.7916 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.3968 |
|
| 188 |
K |
A |
-3.6762 |
|
| 189 |
H |
A |
-3.1164 |
|
| 190 |
K |
A |
-3.1700 |
|
| 191 |
V |
A |
-1.4682 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-1.3024 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.1279 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.5787 |
|
| 200 |
G |
A |
-0.4432 |
|
| 201 |
L |
A |
-0.2018 |
|
| 202 |
S |
A |
-0.4354 |
|
| 203 |
S |
A |
-0.4256 |
|
| 204 |
P |
A |
-0.6780 |
|
| 205 |
V |
A |
-0.2380 |
|
| 206 |
T |
A |
-0.6605 |
|
| 207 |
K |
A |
-0.4944 |
|
| 208 |
S |
A |
-0.3912 |
|
| 209 |
F |
A |
-0.6332 |
|
| 210 |
N |
A |
-1.8976 |
|
| 211 |
R |
A |
-2.4256 |
|
| 212 |
G |
A |
-1.3452 |
|