Project name: 5t1k:D

Chain sequence(s)	D: QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGVIWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALTYYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9764
• Maximal score value: 2.5607
• Average score: -0.5541
• Total score value: -119.1282

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	D	-1.5683
2	V	D	-1.0268
3	Q	D	-1.9164
4	L	D	0.0000
5	K	D	-2.3136
6	Q	D	0.0000
7	S	D	-0.7804
8	G	D	-0.9988
9	P	D	-0.5144
10	G	D	-0.4155
11	L	D	-0.0674
12	V	D	-0.7848
13	Q	D	-1.6709
14	P	D	-1.5979
15	S	D	-1.6057
16	Q	D	-1.8964
17	S	D	-1.9210
18	L	D	0.0000
19	S	D	-0.9855
20	I	D	0.0000
21	T	D	-0.6453
22	C	D	0.0000
23	T	D	-1.2205
24	V	D	0.0000
25	S	D	-1.1865
26	G	D	-1.0681
27	F	D	-0.5877
28	S	D	-0.8913
29	L	D	0.0000
30	T	D	-0.9224
31	N	D	-0.8617
32	Y	D	0.4324
33	G	D	0.0000
34	V	D	0.0000
35	H	D	0.0000
36	W	D	0.0000
37	V	D	0.0000
38	R	D	0.0000
39	Q	D	-0.2843
40	S	D	-0.8908
41	P	D	-1.0706
42	G	D	-1.6061
43	K	D	-2.0052
44	G	D	-0.7167
45	L	D	0.7881
46	E	D	0.0000
47	W	D	0.5889
48	L	D	0.0000
49	G	D	0.0000
50	V	D	0.0000
51	I	D	0.0000
52	W	D	-0.5860
53	S	D	-0.6587
54	G	D	-1.2484
55	G	D	-1.5513
56	N	D	-1.9486
57	T	D	-1.4935
58	D	D	-1.4657
59	Y	D	-0.6749
60	N	D	-0.6441
61	T	D	-0.5408
62	P	D	-0.4792
63	F	D	0.0000
64	T	D	-0.6092
65	S	D	-0.6744
66	R	D	-1.3128
67	L	D	0.0000
68	S	D	-1.4229
69	I	D	0.0000
70	N	D	-1.8950
71	K	D	-1.5107
72	D	D	-1.8107
73	N	D	-2.2349
74	S	D	-1.6919
75	K	D	-2.3553
76	S	D	-1.5908
77	Q	D	-1.5768
78	V	D	0.0000
79	F	D	-0.5918
80	F	D	0.0000
81	K	D	-2.2477
82	M	D	0.0000
83	N	D	-2.3948
84	S	D	-1.7111
85	L	D	0.0000
86	Q	D	-2.2430
87	S	D	-1.5918
88	N	D	-2.0865
89	D	D	0.0000
90	T	D	-0.7248
91	A	D	0.0000
92	I	D	0.4523
93	Y	D	0.0000
94	Y	D	-0.0901
95	C	D	0.0000
96	A	D	0.0000
97	R	D	0.0000
98	A	D	0.0000
99	L	D	1.4106
100	T	D	1.1490
101	Y	D	1.8837
102	Y	D	1.5988
103	D	D	0.3778
104	Y	D	0.4463
105	E	D	-0.9117
106	F	D	0.1154
107	A	D	0.5277
108	Y	D	0.3905
109	W	D	0.0601
110	G	D	0.0000
111	Q	D	-1.5228
112	G	D	-0.6667
113	T	D	0.0000
114	L	D	0.0929
115	V	D	0.0000
116	T	D	-0.3841
117	V	D	0.0000
118	S	D	-0.5877
119	A	D	-0.3665
120	A	D	-0.3118
121	S	D	-0.5540
122	T	D	-0.6364
123	K	D	-1.3261
124	G	D	-1.6014
125	P	D	0.0000
126	S	D	-0.0469
127	V	D	0.0000
128	F	D	1.0989
129	P	D	-0.0709
130	L	D	0.3469
131	A	D	-0.8279
132	P	D	-0.7631
133	S	D	-0.8015
139	G	D	-0.7622
140	G	D	-0.8682
141	T	D	-0.6172
142	A	D	-0.3511
143	A	D	0.0888
144	L	D	0.0000
145	G	D	0.0000
146	C	D	0.0000
147	L	D	0.7714
148	V	D	0.0000
149	K	D	-0.0726
150	D	D	-0.6362
151	Y	D	0.0000
152	F	D	0.0000
153	P	D	0.0000
154	E	D	-0.4806
155	P	D	-0.7442
156	V	D	-0.8457
157	T	D	-0.7565
158	V	D	-0.1877
159	S	D	-0.4987
160	W	D	0.0000
161	N	D	-0.8324
162	S	D	-0.6738
163	G	D	-0.5662
164	A	D	-0.2317
165	L	D	-0.0135
166	T	D	-0.2916
167	S	D	-0.3655
168	G	D	-0.4793
169	V	D	-0.0118
170	H	D	-0.4859
171	T	D	0.1552
172	F	D	1.0097
173	P	D	0.7626
174	A	D	1.3119
175	V	D	2.5607
176	L	D	2.1573
177	Q	D	0.7532
178	S	D	0.1268
179	S	D	-0.2239
180	G	D	0.1975
181	L	D	0.3000
182	Y	D	0.8148
183	S	D	0.0000
184	L	D	0.0000
185	S	D	0.7047
186	S	D	0.0000
187	V	D	0.4457
188	V	D	0.0000
189	T	D	-0.2259
190	V	D	0.0000
191	P	D	-0.5412
192	S	D	-0.5587
193	S	D	-0.5790
194	S	D	-0.5382
195	L	D	-0.7973
196	G	D	-0.9471
197	T	D	-0.6457
198	Q	D	-1.0726
199	T	D	-1.1411
200	Y	D	0.0000
201	I	D	-1.5070
202	C	D	0.0000
203	N	D	-1.6304
204	V	D	0.0000
205	N	D	-2.4885
206	H	D	0.0000
207	K	D	-2.9764
208	P	D	-1.7104
209	S	D	-1.9286
210	N	D	-2.7477
211	T	D	-2.2411
212	K	D	-2.9163
213	V	D	-1.6975
214	D	D	-2.5202
215	K	D	-2.0979
216	R	D	-2.6087
217	V	D	0.0000
218	E	D	-2.8195
219	P	D	-1.8357
220	K	D	-2.2209