Project name: 5jxe:C
Status: done
submitted: 2019-03-20 20:33:37, status changed: 2019-03-20 20:44:30
Settings
|
Chain sequence(s)
|
C: EIVLTQSPATLSLSPGERATLSCRASKGVSTSGYSYLHWYQQKPGQAPRLLIYLASYLESGVPARFSGSGSGTDFTLTISSLEPEDFAVYYCQHSRDLPLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNR
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.0287
-
Maximal score value
-
2.0257
-
Average score
-
-0.7102
-
Total score value
-
-152.7037
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
C |
-1.4468 |
|
| 2 |
I |
C |
0.0000 |
|
| 3 |
V |
C |
1.0086 |
|
| 4 |
L |
C |
0.0000 |
|
| 5 |
T |
C |
-0.2877 |
|
| 6 |
Q |
C |
0.0000 |
|
| 7 |
S |
C |
-0.6551 |
|
| 8 |
P |
C |
-0.3745 |
|
| 9 |
A |
C |
-0.2275 |
|
| 10 |
T |
C |
-0.2757 |
|
| 11 |
L |
C |
-0.2208 |
|
| 12 |
S |
C |
-0.8656 |
|
| 13 |
L |
C |
0.0000 |
|
| 14 |
S |
C |
-1.6383 |
|
| 15 |
P |
C |
-1.8252 |
|
| 16 |
G |
C |
-2.1470 |
|
| 17 |
E |
C |
-3.1897 |
|
| 18 |
R |
C |
-3.0788 |
|
| 19 |
A |
C |
-1.4288 |
|
| 20 |
T |
C |
-0.5122 |
|
| 21 |
L |
C |
0.0000 |
|
| 22 |
S |
C |
-0.7347 |
|
| 23 |
C |
C |
0.0000 |
|
| 24 |
R |
C |
-2.1566 |
|
| 25 |
A |
C |
-1.2277 |
|
| 26 |
S |
C |
-1.2064 |
|
| 27 |
K |
C |
-2.2396 |
|
| 28 |
G |
C |
-1.5869 |
|
| 29 |
V |
C |
0.0000 |
|
| 30 |
S |
C |
-0.4736 |
|
| 31 |
T |
C |
-0.2230 |
|
| 32 |
S |
C |
-0.2141 |
|
| 33 |
G |
C |
-0.1782 |
|
| 34 |
Y |
C |
0.5333 |
|
| 35 |
S |
C |
0.0000 |
|
| 36 |
Y |
C |
0.0551 |
|
| 37 |
L |
C |
0.0000 |
|
| 38 |
H |
C |
0.6009 |
|
| 39 |
W |
C |
0.0000 |
|
| 40 |
Y |
C |
0.0594 |
|
| 41 |
Q |
C |
0.0000 |
|
| 42 |
Q |
C |
-1.3286 |
|
| 43 |
K |
C |
-1.9610 |
|
| 44 |
P |
C |
-1.5428 |
|
| 45 |
G |
C |
-1.4453 |
|
| 46 |
Q |
C |
-2.0566 |
|
| 47 |
A |
C |
-1.3128 |
|
| 48 |
P |
C |
-1.3330 |
|
| 49 |
R |
C |
-1.7471 |
|
| 50 |
L |
C |
-0.3257 |
|
| 51 |
L |
C |
0.0000 |
|
| 52 |
I |
C |
0.0000 |
|
| 53 |
Y |
C |
0.8291 |
|
| 54 |
L |
C |
0.8673 |
|
| 55 |
A |
C |
0.0000 |
|
| 56 |
S |
C |
0.2668 |
|
| 57 |
Y |
C |
0.8431 |
|
| 58 |
L |
C |
0.7351 |
|
| 59 |
E |
C |
-0.4120 |
|
| 60 |
S |
C |
-0.4763 |
|
| 61 |
G |
C |
-0.6589 |
|
| 62 |
V |
C |
0.0000 |
|
| 63 |
P |
C |
-0.3754 |
|
| 64 |
A |
C |
-0.1714 |
|
| 65 |
R |
C |
-0.7643 |
|
| 66 |
F |
C |
0.0000 |
|
| 67 |
S |
C |
-0.1496 |
|
| 68 |
G |
C |
-0.0798 |
|
| 69 |
S |
C |
-0.5117 |
|
| 70 |
G |
C |
-0.9343 |
|
| 71 |
S |
C |
-0.7217 |
|
| 72 |
G |
C |
-0.9080 |
|
| 73 |
T |
C |
-1.5092 |
|
| 74 |
D |
C |
-1.6566 |
|
| 75 |
F |
C |
0.0000 |
|
| 76 |
T |
C |
-0.6732 |
|
| 77 |
L |
C |
0.0000 |
|
| 78 |
T |
C |
-0.6108 |
|
| 79 |
I |
C |
0.0000 |
|
| 80 |
S |
C |
-1.6348 |
|
| 81 |
S |
C |
-1.6998 |
|
| 82 |
L |
C |
0.0000 |
|
| 83 |
E |
C |
-1.8924 |
|
| 84 |
P |
C |
-1.4144 |
|
| 85 |
E |
C |
-2.1736 |
|
| 86 |
D |
C |
0.0000 |
|
| 87 |
F |
C |
-0.6102 |
|
| 88 |
A |
C |
0.0000 |
|
| 89 |
V |
C |
-0.1333 |
|
| 90 |
Y |
C |
0.0000 |
|
| 91 |
Y |
C |
0.3883 |
|
| 92 |
C |
C |
0.0000 |
|
| 93 |
Q |
C |
0.0000 |
|
| 94 |
H |
C |
0.0000 |
|
| 95 |
S |
C |
-0.1708 |
|
| 96 |
R |
C |
-1.4382 |
|
| 97 |
D |
C |
-1.5796 |
|
| 98 |
L |
C |
0.2993 |
|
| 99 |
P |
C |
0.2974 |
|
| 100 |
L |
C |
1.1285 |
|
| 101 |
T |
C |
1.2685 |
|
| 102 |
F |
C |
2.0257 |
|
| 103 |
G |
C |
0.6391 |
|
| 104 |
G |
C |
0.0679 |
|
| 105 |
G |
C |
-0.0108 |
|
| 106 |
T |
C |
0.0000 |
|
| 107 |
K |
C |
-0.2038 |
|
| 108 |
V |
C |
0.0000 |
|
| 109 |
E |
C |
0.0000 |
|
| 110 |
I |
C |
-0.6356 |
|
| 111 |
K |
C |
-1.3161 |
|
| 112 |
R |
C |
-0.8401 |
|
| 113 |
T |
C |
0.2665 |
|
| 114 |
V |
C |
1.1106 |
|
| 115 |
A |
C |
0.3978 |
|
| 116 |
A |
C |
-0.0280 |
|
| 117 |
P |
C |
0.0000 |
|
| 118 |
S |
C |
-0.0252 |
|
| 119 |
V |
C |
0.3920 |
|
| 120 |
F |
C |
1.2450 |
|
| 121 |
I |
C |
1.4628 |
|
| 122 |
F |
C |
1.9503 |
|
| 123 |
P |
C |
0.3036 |
|
| 124 |
P |
C |
0.0000 |
|
| 125 |
S |
C |
-1.8229 |
|
| 126 |
D |
C |
-3.3431 |
|
| 127 |
E |
C |
-3.5751 |
|
| 128 |
Q |
C |
-2.7267 |
|
| 129 |
L |
C |
0.0000 |
|
| 130 |
K |
C |
-3.1743 |
|
| 131 |
S |
C |
-1.6561 |
|
| 132 |
G |
C |
-1.7018 |
|
| 133 |
T |
C |
-1.2114 |
|
| 134 |
A |
C |
0.0000 |
|
| 135 |
S |
C |
-0.0063 |
|
| 136 |
V |
C |
0.0000 |
|
| 137 |
V |
C |
0.7020 |
|
| 138 |
C |
C |
0.0000 |
|
| 139 |
L |
C |
0.5945 |
|
| 140 |
L |
C |
0.0000 |
|
| 141 |
N |
C |
-0.4969 |
|
| 142 |
N |
C |
-1.5333 |
|
| 143 |
F |
C |
0.0000 |
|
| 144 |
Y |
C |
0.0000 |
|
| 145 |
P |
C |
-1.4568 |
|
| 146 |
R |
C |
-2.5129 |
|
| 147 |
E |
C |
-3.0714 |
|
| 148 |
A |
C |
-2.2754 |
|
| 149 |
K |
C |
-2.4971 |
|
| 150 |
V |
C |
-1.2893 |
|
| 151 |
Q |
C |
-0.9798 |
|
| 152 |
W |
C |
0.0000 |
|
| 153 |
K |
C |
-0.6911 |
|
| 154 |
V |
C |
0.0000 |
|
| 155 |
D |
C |
-1.7383 |
|
| 156 |
N |
C |
-1.3568 |
|
| 157 |
A |
C |
-0.3918 |
|
| 158 |
L |
C |
0.5873 |
|
| 159 |
Q |
C |
-0.3018 |
|
| 160 |
S |
C |
-0.5477 |
|
| 161 |
G |
C |
-0.9574 |
|
| 162 |
N |
C |
-1.1921 |
|
| 163 |
S |
C |
-1.6241 |
|
| 164 |
Q |
C |
-2.3298 |
|
| 165 |
E |
C |
-2.2740 |
|
| 166 |
S |
C |
-1.2616 |
|
| 167 |
V |
C |
-0.5803 |
|
| 168 |
T |
C |
-0.9906 |
|
| 169 |
E |
C |
-2.0465 |
|
| 170 |
Q |
C |
-2.0565 |
|
| 171 |
D |
C |
-2.4418 |
|
| 172 |
S |
C |
-2.0348 |
|
| 173 |
K |
C |
-2.7486 |
|
| 174 |
D |
C |
-2.7753 |
|
| 175 |
S |
C |
-2.2188 |
|
| 176 |
T |
C |
0.0000 |
|
| 177 |
Y |
C |
0.0000 |
|
| 178 |
S |
C |
-0.8986 |
|
| 179 |
L |
C |
-0.6015 |
|
| 180 |
S |
C |
-0.3748 |
|
| 181 |
S |
C |
0.0000 |
|
| 182 |
T |
C |
-0.6390 |
|
| 183 |
L |
C |
0.0000 |
|
| 184 |
T |
C |
-0.3681 |
|
| 185 |
L |
C |
-0.7892 |
|
| 186 |
S |
C |
-1.2234 |
|
| 187 |
K |
C |
-2.3213 |
|
| 188 |
A |
C |
-2.1881 |
|
| 189 |
D |
C |
-3.0151 |
|
| 190 |
Y |
C |
0.0000 |
|
| 191 |
E |
C |
-4.0287 |
|
| 192 |
K |
C |
-3.7532 |
|
| 193 |
H |
C |
-3.3129 |
|
| 194 |
K |
C |
-3.1815 |
|
| 195 |
V |
C |
-1.4485 |
|
| 196 |
Y |
C |
0.0000 |
|
| 197 |
A |
C |
-0.4747 |
|
| 198 |
C |
C |
0.0000 |
|
| 199 |
E |
C |
-0.8397 |
|
| 200 |
V |
C |
0.0000 |
|
| 201 |
T |
C |
-1.2088 |
|
| 202 |
H |
C |
0.0000 |
|
| 203 |
Q |
C |
-1.6308 |
|
| 204 |
G |
C |
-0.2204 |
|
| 205 |
L |
C |
-0.0298 |
|
| 206 |
S |
C |
-0.3462 |
|
| 207 |
S |
C |
-0.3165 |
|
| 208 |
P |
C |
-0.3030 |
|
| 209 |
V |
C |
0.4363 |
|
| 210 |
T |
C |
-0.1966 |
|
| 211 |
K |
C |
-0.2338 |
|
| 212 |
S |
C |
0.0825 |
|
| 213 |
F |
C |
0.1512 |
|
| 214 |
N |
C |
-1.7682 |
|
| 215 |
R |
C |
-2.8095 |
|