Project name: 2b5335b0fa5d586

Chain sequence(s)	A: QMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYR
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2849
• Maximal score value: 1.3342
• Average score: -0.6913
• Total score value: -136.1951

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
9	Q	A	-2.1553
10	M	A	-2.3902
11	K	A	-2.9754
12	E	A	-3.1230
13	E	A	-2.5794
14	D	A	0.0000
15	V	A	-0.5493
16	L	A	0.5561
17	K	A	-0.1362
18	F	A	0.0000
19	L	A	1.3342
20	A	A	0.6308
21	A	A	0.1170
22	G	A	0.2360
23	T	A	0.0000
24	H	A	0.6864
25	L	A	0.8331
26	G	A	0.0000
27	G	A	-0.7325
28	T	A	-1.1334
29	N	A	-1.1153
30	L	A	-0.5931
31	D	A	-0.5284
32	F	A	0.5188
33	Q	A	-0.9606
34	M	A	0.0000
35	E	A	-1.8854
36	Q	A	-1.8052
37	Y	A	0.0000
38	I	A	-0.5526
39	Y	A	-0.2444
40	K	A	-1.8122
41	R	A	-2.8532
42	K	A	-2.8831
43	S	A	-1.9957
44	D	A	-2.4896
45	G	A	-2.0371
46	I	A	-1.3018
47	Y	A	-1.2511
48	I	A	-0.1658
49	I	A	0.0000
50	N	A	-0.6134
51	L	A	0.0000
52	K	A	-2.3403
53	R	A	-1.8908
54	T	A	0.0000
55	W	A	0.0000
56	E	A	-1.8613
57	K	A	-1.1481
58	L	A	0.0000
59	L	A	-0.5235
60	L	A	-0.3165
61	A	A	0.0000
62	A	A	0.0000
63	R	A	-1.4407
64	A	A	-0.4572
65	I	A	0.0000
66	V	A	-0.6334
67	A	A	-0.7774
68	I	A	-1.3829
69	E	A	-2.4066
70	N	A	-2.3406
71	P	A	-1.3606
72	A	A	-1.2706
73	D	A	-2.0729
74	V	A	0.0000
75	S	A	0.0000
76	V	A	0.0000
77	I	A	0.0000
78	S	A	0.0000
79	S	A	-1.3171
80	R	A	-1.5954
81	N	A	-2.0985
82	T	A	-1.7581
83	G	A	0.0000
84	Q	A	-1.6336
85	R	A	-2.0260
86	A	A	0.0000
87	V	A	0.0000
88	L	A	-0.1465
89	K	A	-0.5576
90	F	A	0.0000
91	A	A	0.0000
92	A	A	-0.0085
93	A	A	-0.0242
94	T	A	0.0000
95	G	A	-0.5605
96	A	A	0.0000
97	T	A	0.0068
98	P	A	0.1322
99	I	A	0.0076
100	A	A	-0.9388
101	G	A	-1.6443
102	R	A	-1.9515
103	F	A	0.0000
104	T	A	-0.8089
105	P	A	-0.8880
106	G	A	-0.9034
107	T	A	-0.7142
108	F	A	0.0000
109	T	A	-0.3163
110	N	A	-1.3178
111	Q	A	-0.9386
112	I	A	0.7359
113	Q	A	-0.5240
114	A	A	-0.1241
115	A	A	0.3003
116	F	A	0.6598
117	R	A	-1.2335
118	E	A	-2.5613
119	P	A	-1.9458
120	R	A	-2.6813
121	L	A	0.0000
122	L	A	0.0000
123	V	A	0.0000
124	V	A	0.0000
125	T	A	0.0000
126	D	A	0.0000
127	P	A	0.0000
128	R	A	-1.9964
129	A	A	-1.1121
130	D	A	0.0000
131	H	A	-1.3073
132	Q	A	-1.1108
133	P	A	0.0000
134	L	A	0.0000
135	T	A	-0.2566
136	E	A	0.0000
137	A	A	0.0000
138	S	A	-0.1462
139	Y	A	1.1311
140	V	A	0.1207
141	N	A	-0.9410
142	L	A	0.0000
143	P	A	-1.1027
144	T	A	0.0000
145	I	A	0.0000
146	A	A	0.0000
147	L	A	0.0000
148	C	A	0.0000
149	N	A	0.0000
150	T	A	0.0000
151	D	A	-1.1701
152	S	A	0.0000
153	P	A	-0.9819
154	L	A	0.0000
155	R	A	-2.0708
156	Y	A	-0.8885
157	V	A	-1.0894
158	D	A	-1.8375
159	I	A	-0.4977
160	A	A	0.0000
161	I	A	0.0000
162	P	A	0.0000
163	C	A	0.0000
164	N	A	0.0000
165	N	A	0.0000
166	K	A	-1.7988
167	G	A	-1.0448
168	A	A	-1.1821
169	H	A	-1.5849
170	S	A	0.0000
171	V	A	0.0000
172	G	A	0.0000
173	L	A	0.0000
174	M	A	0.0000
175	W	A	0.0000
176	W	A	0.0000
177	M	A	0.0000
178	L	A	0.0000
179	A	A	0.0000
180	R	A	0.0000
181	E	A	0.0000
182	V	A	0.0000
183	L	A	0.0000
184	R	A	-1.2318
185	M	A	-0.8784
186	R	A	-1.1918
187	G	A	-1.1354
188	T	A	-0.6819
189	I	A	-1.1898
190	S	A	-2.0362
191	R	A	-3.2123
192	E	A	-3.2849
193	H	A	-2.6818
194	P	A	-1.9318
195	W	A	0.0000
196	E	A	-1.6049
197	V	A	-0.3045
198	M	A	0.1443
199	P	A	-0.5191
200	D	A	-1.3228
201	L	A	-0.0451
202	Y	A	0.0000
203	F	A	-1.0895
204	Y	A	-1.3968
205	R	A	-2.1839