Project name: 4qxg:L
Status: done
submitted: 2019-03-20 20:21:34, status changed: 2019-03-20 20:33:18
Settings
|
Chain sequence(s)
|
L: EIVLTQSPGTLSLSPGERATLSCRASQSVSSSFFAWYQQKPGQAPRLLIYGASSRATGIPDRLSGSGSGTDFTLTITRLEPEDFAVYYCQQYDSSAITFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5493
-
Maximal score value
-
2.1687
-
Average score
-
-0.859
-
Total score value
-
-183.8203
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
L |
-1.2418 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
V |
L |
1.0165 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.6745 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.8185 |
|
| 8 |
P |
L |
-0.5097 |
|
| 9 |
G |
L |
-0.8675 |
|
| 10 |
T |
L |
-0.4453 |
|
| 11 |
L |
L |
-0.1337 |
|
| 12 |
S |
L |
-0.3505 |
|
| 13 |
L |
L |
-0.8760 |
|
| 14 |
S |
L |
-1.5489 |
|
| 15 |
P |
L |
-2.0260 |
|
| 16 |
G |
L |
-2.2867 |
|
| 17 |
E |
L |
-2.9578 |
|
| 18 |
R |
L |
-3.1739 |
|
| 19 |
A |
L |
0.0000 |
|
| 20 |
T |
L |
-0.5209 |
|
| 21 |
L |
L |
0.0000 |
|
| 22 |
S |
L |
-0.9845 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.5890 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-1.1290 |
|
| 27 |
Q |
L |
-1.8024 |
|
| 28 |
S |
L |
-1.5666 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
S |
L |
-0.2536 |
|
| 31 |
S |
L |
-0.3114 |
|
| 32 |
S |
L |
0.2056 |
|
| 33 |
F |
L |
0.8018 |
|
| 34 |
F |
L |
0.0000 |
|
| 35 |
A |
L |
0.0000 |
|
| 36 |
W |
L |
0.0000 |
|
| 37 |
Y |
L |
0.0963 |
|
| 38 |
Q |
L |
0.0000 |
|
| 39 |
Q |
L |
-1.3830 |
|
| 40 |
K |
L |
-2.0645 |
|
| 41 |
P |
L |
-1.5805 |
|
| 42 |
G |
L |
-1.5882 |
|
| 43 |
Q |
L |
-2.0604 |
|
| 44 |
A |
L |
-1.4281 |
|
| 45 |
P |
L |
-1.5033 |
|
| 46 |
R |
L |
-1.9234 |
|
| 47 |
L |
L |
-0.3081 |
|
| 48 |
L |
L |
0.0000 |
|
| 49 |
I |
L |
0.0000 |
|
| 50 |
Y |
L |
0.8005 |
|
| 51 |
G |
L |
0.2892 |
|
| 52 |
A |
L |
0.0000 |
|
| 53 |
S |
L |
-0.4833 |
|
| 54 |
S |
L |
-0.4842 |
|
| 55 |
R |
L |
-1.2267 |
|
| 56 |
A |
L |
-0.5549 |
|
| 57 |
T |
L |
-0.4426 |
|
| 58 |
G |
L |
-0.8191 |
|
| 59 |
I |
L |
-0.7706 |
|
| 60 |
P |
L |
-1.2488 |
|
| 61 |
D |
L |
-2.3416 |
|
| 62 |
R |
L |
-1.9223 |
|
| 63 |
L |
L |
0.0000 |
|
| 64 |
S |
L |
-0.8809 |
|
| 65 |
G |
L |
-0.4111 |
|
| 66 |
S |
L |
-0.6672 |
|
| 67 |
G |
L |
-1.2491 |
|
| 68 |
S |
L |
-1.2423 |
|
| 69 |
G |
L |
-1.4319 |
|
| 70 |
T |
L |
-2.1234 |
|
| 71 |
D |
L |
-2.8823 |
|
| 72 |
F |
L |
0.0000 |
|
| 73 |
T |
L |
-0.9103 |
|
| 74 |
L |
L |
0.0000 |
|
| 75 |
T |
L |
-0.7577 |
|
| 76 |
I |
L |
0.0000 |
|
| 77 |
T |
L |
-2.4378 |
|
| 78 |
R |
L |
-3.3772 |
|
| 79 |
L |
L |
0.0000 |
|
| 80 |
E |
L |
-2.4773 |
|
| 81 |
P |
L |
-1.7621 |
|
| 82 |
E |
L |
-2.2928 |
|
| 83 |
D |
L |
0.0000 |
|
| 84 |
F |
L |
-0.7608 |
|
| 85 |
A |
L |
0.0000 |
|
| 86 |
V |
L |
-0.1019 |
|
| 87 |
Y |
L |
0.0000 |
|
| 88 |
Y |
L |
0.1832 |
|
| 89 |
C |
L |
0.0000 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Q |
L |
0.0000 |
|
| 92 |
Y |
L |
1.3382 |
|
| 93 |
D |
L |
-0.0761 |
|
| 94 |
S |
L |
-0.0382 |
|
| 95 |
S |
L |
0.0297 |
|
| 96 |
A |
L |
0.4072 |
|
| 97 |
I |
L |
2.1687 |
|
| 98 |
T |
L |
1.5523 |
|
| 99 |
F |
L |
1.9529 |
|
| 100 |
G |
L |
0.0000 |
|
| 101 |
Q |
L |
-0.7850 |
|
| 102 |
G |
L |
0.0000 |
|
| 103 |
T |
L |
0.0000 |
|
| 104 |
R |
L |
-0.7440 |
|
| 105 |
L |
L |
0.0000 |
|
| 106 |
E |
L |
0.0000 |
|
| 107 |
I |
L |
-0.7819 |
|
| 108 |
K |
L |
-1.2926 |
|
| 109 |
R |
L |
-1.0607 |
|
| 110 |
T |
L |
-0.2291 |
|
| 111 |
V |
L |
0.0995 |
|
| 112 |
A |
L |
-0.0789 |
|
| 113 |
A |
L |
-0.2372 |
|
| 114 |
P |
L |
0.0000 |
|
| 115 |
S |
L |
-0.1081 |
|
| 116 |
V |
L |
0.0000 |
|
| 117 |
F |
L |
1.1947 |
|
| 118 |
I |
L |
1.1865 |
|
| 119 |
F |
L |
1.4178 |
|
| 120 |
P |
L |
0.0286 |
|
| 121 |
P |
L |
-0.7308 |
|
| 122 |
S |
L |
-1.8283 |
|
| 123 |
D |
L |
-3.2615 |
|
| 124 |
E |
L |
-3.4426 |
|
| 125 |
Q |
L |
-2.5122 |
|
| 126 |
L |
L |
-2.5246 |
|
| 127 |
K |
L |
-3.0667 |
|
| 128 |
S |
L |
-1.9688 |
|
| 129 |
G |
L |
-1.5464 |
|
| 130 |
T |
L |
-1.2310 |
|
| 131 |
A |
L |
0.0000 |
|
| 132 |
S |
L |
0.0313 |
|
| 133 |
V |
L |
0.0000 |
|
| 134 |
V |
L |
0.7130 |
|
| 135 |
C |
L |
0.0000 |
|
| 136 |
L |
L |
0.4870 |
|
| 137 |
L |
L |
0.0000 |
|
| 138 |
N |
L |
-0.5628 |
|
| 139 |
N |
L |
-1.2804 |
|
| 140 |
F |
L |
0.0000 |
|
| 141 |
Y |
L |
0.0000 |
|
| 142 |
P |
L |
-1.7091 |
|
| 143 |
R |
L |
-2.8217 |
|
| 144 |
E |
L |
-3.0530 |
|
| 145 |
A |
L |
-2.2401 |
|
| 146 |
K |
L |
-2.4085 |
|
| 147 |
V |
L |
-1.2632 |
|
| 148 |
Q |
L |
-0.7885 |
|
| 149 |
W |
L |
0.0000 |
|
| 150 |
K |
L |
-0.8715 |
|
| 151 |
V |
L |
0.0000 |
|
| 152 |
D |
L |
-1.9776 |
|
| 153 |
N |
L |
-1.6638 |
|
| 154 |
A |
L |
-0.5490 |
|
| 155 |
L |
L |
0.0653 |
|
| 156 |
Q |
L |
-0.6927 |
|
| 157 |
S |
L |
-0.8583 |
|
| 158 |
G |
L |
-1.4797 |
|
| 159 |
N |
L |
-1.9223 |
|
| 160 |
S |
L |
-1.9135 |
|
| 161 |
Q |
L |
-2.4900 |
|
| 162 |
E |
L |
-2.3847 |
|
| 163 |
S |
L |
-1.4145 |
|
| 164 |
V |
L |
-1.0623 |
|
| 165 |
T |
L |
-1.3075 |
|
| 166 |
E |
L |
-2.4999 |
|
| 167 |
Q |
L |
-2.1147 |
|
| 168 |
D |
L |
-2.3638 |
|
| 169 |
S |
L |
-2.1432 |
|
| 170 |
K |
L |
-2.3825 |
|
| 171 |
D |
L |
-1.8344 |
|
| 172 |
S |
L |
-1.8809 |
|
| 173 |
T |
L |
0.0000 |
|
| 174 |
Y |
L |
0.0000 |
|
| 175 |
S |
L |
-1.0228 |
|
| 176 |
L |
L |
0.0000 |
|
| 177 |
S |
L |
-0.5490 |
|
| 178 |
S |
L |
0.0000 |
|
| 179 |
T |
L |
-0.7452 |
|
| 180 |
L |
L |
0.0000 |
|
| 181 |
T |
L |
-0.7541 |
|
| 182 |
L |
L |
-0.8506 |
|
| 183 |
S |
L |
-1.0374 |
|
| 184 |
K |
L |
-2.0484 |
|
| 185 |
A |
L |
-1.8127 |
|
| 186 |
D |
L |
-2.7805 |
|
| 187 |
Y |
L |
0.0000 |
|
| 188 |
E |
L |
-3.2505 |
|
| 189 |
K |
L |
-3.5493 |
|
| 190 |
H |
L |
-3.0338 |
|
| 191 |
K |
L |
-3.3941 |
|
| 192 |
V |
L |
-1.4217 |
|
| 193 |
Y |
L |
0.0000 |
|
| 194 |
A |
L |
0.0000 |
|
| 195 |
C |
L |
0.0000 |
|
| 196 |
E |
L |
-0.8125 |
|
| 197 |
V |
L |
0.0000 |
|
| 198 |
T |
L |
-1.1387 |
|
| 199 |
H |
L |
0.0000 |
|
| 200 |
Q |
L |
-1.7643 |
|
| 201 |
G |
L |
-0.5226 |
|
| 202 |
L |
L |
-0.2618 |
|
| 203 |
S |
L |
-0.4479 |
|
| 204 |
S |
L |
-0.4060 |
|
| 205 |
P |
L |
-0.4719 |
|
| 206 |
V |
L |
-0.0104 |
|
| 207 |
T |
L |
-0.4522 |
|
| 208 |
K |
L |
-0.5123 |
|
| 209 |
S |
L |
-0.3299 |
|
| 210 |
F |
L |
-0.8108 |
|
| 211 |
N |
L |
-2.0089 |
|
| 212 |
R |
L |
-2.5551 |
|
| 213 |
G |
L |
-2.1602 |
|
| 214 |
E |
L |
-2.5238 |
|