Project name: 5bvj:A
Status: done
submitted: 2019-03-20 20:24:10, status changed: 2019-03-20 20:35:04
Settings
|
Chain sequence(s)
|
A: EIVLTQSPDFQSVTPKEKVTITCRASQSIGSSLHWYQQKPDQSPKLLIKYASQSFSGVPSRFSGSGSGTDFTLTINSLEAEDAAAYYCHQSSSLPFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.9657
-
Maximal score value
-
2.3164
-
Average score
-
-0.817
-
Total score value
-
-174.8462
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
A |
-0.8867 |
|
| 2 |
I |
A |
0.4399 |
|
| 3 |
V |
A |
1.2564 |
|
| 4 |
L |
A |
0.0000 |
|
| 5 |
T |
A |
-0.4485 |
|
| 6 |
Q |
A |
0.0000 |
|
| 7 |
S |
A |
-1.1727 |
|
| 8 |
P |
A |
-1.1250 |
|
| 9 |
D |
A |
-2.0062 |
|
| 10 |
F |
A |
-1.0649 |
|
| 11 |
Q |
A |
-0.8500 |
|
| 12 |
S |
A |
-0.9300 |
|
| 13 |
V |
A |
0.0000 |
|
| 14 |
T |
A |
-2.0484 |
|
| 15 |
P |
A |
-2.6468 |
|
| 16 |
K |
A |
-3.4845 |
|
| 17 |
E |
A |
-3.9657 |
|
| 18 |
K |
A |
-3.3811 |
|
| 19 |
V |
A |
0.0000 |
|
| 20 |
T |
A |
-0.6169 |
|
| 21 |
I |
A |
0.0000 |
|
| 22 |
T |
A |
-0.9849 |
|
| 23 |
C |
A |
0.0000 |
|
| 24 |
R |
A |
-2.3010 |
|
| 25 |
A |
A |
0.0000 |
|
| 26 |
S |
A |
-0.9057 |
|
| 27 |
Q |
A |
-1.6851 |
|
| 28 |
S |
A |
-1.4197 |
|
| 29 |
I |
A |
0.0000 |
|
| 30 |
G |
A |
-0.7777 |
|
| 31 |
S |
A |
-0.3817 |
|
| 32 |
S |
A |
-0.0621 |
|
| 33 |
L |
A |
0.0000 |
|
| 34 |
H |
A |
0.0000 |
|
| 35 |
W |
A |
0.0000 |
|
| 36 |
Y |
A |
-0.2165 |
|
| 37 |
Q |
A |
0.0000 |
|
| 38 |
Q |
A |
-1.6847 |
|
| 39 |
K |
A |
-2.2634 |
|
| 40 |
P |
A |
-2.1838 |
|
| 41 |
D |
A |
-2.7386 |
|
| 42 |
Q |
A |
-2.7290 |
|
| 43 |
S |
A |
-1.7978 |
|
| 44 |
P |
A |
-1.5523 |
|
| 45 |
K |
A |
-1.4524 |
|
| 46 |
L |
A |
-0.3554 |
|
| 47 |
L |
A |
0.0000 |
|
| 48 |
I |
A |
0.0000 |
|
| 49 |
K |
A |
-0.4140 |
|
| 50 |
Y |
A |
0.3994 |
|
| 51 |
A |
A |
0.0000 |
|
| 52 |
S |
A |
-0.7154 |
|
| 53 |
Q |
A |
-1.0536 |
|
| 54 |
S |
A |
-0.3354 |
|
| 55 |
F |
A |
0.4159 |
|
| 56 |
S |
A |
0.0217 |
|
| 57 |
G |
A |
-0.2562 |
|
| 58 |
V |
A |
-0.0731 |
|
| 59 |
P |
A |
-0.3038 |
|
| 60 |
S |
A |
-0.5849 |
|
| 61 |
R |
A |
-1.0777 |
|
| 62 |
F |
A |
0.0000 |
|
| 63 |
S |
A |
-0.6340 |
|
| 64 |
G |
A |
0.0000 |
|
| 65 |
S |
A |
-0.6458 |
|
| 66 |
G |
A |
-0.7913 |
|
| 67 |
S |
A |
-0.9947 |
|
| 68 |
G |
A |
-1.2892 |
|
| 69 |
T |
A |
-1.8255 |
|
| 70 |
D |
A |
-2.2071 |
|
| 71 |
F |
A |
0.0000 |
|
| 72 |
T |
A |
-0.7416 |
|
| 73 |
L |
A |
0.0000 |
|
| 74 |
T |
A |
-0.6627 |
|
| 75 |
I |
A |
0.0000 |
|
| 76 |
N |
A |
-2.3188 |
|
| 77 |
S |
A |
-2.7768 |
|
| 78 |
L |
A |
0.0000 |
|
| 79 |
E |
A |
-2.7870 |
|
| 80 |
A |
A |
-1.7641 |
|
| 81 |
E |
A |
-2.2661 |
|
| 82 |
D |
A |
0.0000 |
|
| 83 |
A |
A |
-1.2309 |
|
| 84 |
A |
A |
0.0000 |
|
| 85 |
A |
A |
-0.8491 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
Y |
A |
0.2647 |
|
| 88 |
C |
A |
0.0000 |
|
| 89 |
H |
A |
1.1967 |
|
| 90 |
Q |
A |
0.0000 |
|
| 91 |
S |
A |
0.9256 |
|
| 92 |
S |
A |
0.1568 |
|
| 93 |
S |
A |
0.5178 |
|
| 94 |
L |
A |
1.6107 |
|
| 95 |
P |
A |
1.0232 |
|
| 96 |
F |
A |
2.2245 |
|
| 97 |
T |
A |
1.7918 |
|
| 98 |
F |
A |
2.3164 |
|
| 99 |
G |
A |
0.0000 |
|
| 100 |
P |
A |
0.0531 |
|
| 101 |
G |
A |
-0.4176 |
|
| 102 |
T |
A |
0.0000 |
|
| 103 |
K |
A |
-1.4214 |
|
| 104 |
V |
A |
0.0000 |
|
| 105 |
D |
A |
0.0000 |
|
| 106 |
I |
A |
-1.0685 |
|
| 107 |
K |
A |
-1.3946 |
|
| 108 |
R |
A |
-0.9885 |
|
| 109 |
T |
A |
-0.2347 |
|
| 110 |
V |
A |
-0.0066 |
|
| 111 |
A |
A |
-0.3590 |
|
| 112 |
A |
A |
-0.3520 |
|
| 113 |
P |
A |
0.0000 |
|
| 114 |
S |
A |
-0.0909 |
|
| 115 |
V |
A |
0.0000 |
|
| 116 |
F |
A |
1.4353 |
|
| 117 |
I |
A |
1.4921 |
|
| 118 |
F |
A |
1.7826 |
|
| 119 |
P |
A |
-0.0421 |
|
| 120 |
P |
A |
-0.5787 |
|
| 121 |
S |
A |
-1.7397 |
|
| 122 |
D |
A |
-3.3028 |
|
| 123 |
E |
A |
-3.4748 |
|
| 124 |
Q |
A |
-2.5117 |
|
| 125 |
L |
A |
-2.5280 |
|
| 126 |
K |
A |
-3.0973 |
|
| 127 |
S |
A |
-1.9916 |
|
| 128 |
G |
A |
-1.3649 |
|
| 129 |
T |
A |
-1.4047 |
|
| 130 |
A |
A |
0.0000 |
|
| 131 |
S |
A |
0.0938 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
V |
A |
0.8144 |
|
| 134 |
C |
A |
0.0000 |
|
| 135 |
L |
A |
0.5515 |
|
| 136 |
L |
A |
0.0000 |
|
| 137 |
N |
A |
-0.6023 |
|
| 138 |
N |
A |
-1.2694 |
|
| 139 |
F |
A |
0.0000 |
|
| 140 |
Y |
A |
0.0000 |
|
| 141 |
P |
A |
-1.4990 |
|
| 142 |
R |
A |
-2.3248 |
|
| 143 |
E |
A |
-2.8426 |
|
| 144 |
A |
A |
-2.0347 |
|
| 145 |
K |
A |
-2.3836 |
|
| 146 |
V |
A |
-1.2968 |
|
| 147 |
Q |
A |
-1.1044 |
|
| 148 |
W |
A |
0.0000 |
|
| 149 |
K |
A |
-0.5236 |
|
| 150 |
V |
A |
0.0000 |
|
| 151 |
D |
A |
-1.5441 |
|
| 152 |
N |
A |
-1.3332 |
|
| 153 |
A |
A |
-0.1053 |
|
| 154 |
L |
A |
0.6654 |
|
| 155 |
Q |
A |
-0.1937 |
|
| 156 |
S |
A |
-0.6200 |
|
| 157 |
G |
A |
-1.0110 |
|
| 158 |
N |
A |
-0.9673 |
|
| 159 |
S |
A |
-1.4988 |
|
| 160 |
Q |
A |
-2.3341 |
|
| 161 |
E |
A |
-2.3316 |
|
| 162 |
S |
A |
-1.1166 |
|
| 163 |
V |
A |
-0.6113 |
|
| 164 |
T |
A |
-1.1206 |
|
| 165 |
E |
A |
-2.1416 |
|
| 166 |
Q |
A |
-1.8985 |
|
| 167 |
D |
A |
-2.0259 |
|
| 168 |
S |
A |
-1.9534 |
|
| 169 |
K |
A |
-2.3857 |
|
| 170 |
D |
A |
-2.0479 |
|
| 171 |
S |
A |
-1.9321 |
|
| 172 |
T |
A |
0.0000 |
|
| 173 |
Y |
A |
0.0000 |
|
| 174 |
S |
A |
-0.8731 |
|
| 175 |
L |
A |
0.0000 |
|
| 176 |
S |
A |
-0.4694 |
|
| 177 |
S |
A |
0.0000 |
|
| 178 |
T |
A |
-0.6221 |
|
| 179 |
L |
A |
0.0000 |
|
| 180 |
T |
A |
-0.5148 |
|
| 181 |
L |
A |
-0.7579 |
|
| 182 |
S |
A |
-1.1457 |
|
| 183 |
K |
A |
-2.1696 |
|
| 184 |
A |
A |
-2.0149 |
|
| 185 |
D |
A |
-2.8310 |
|
| 186 |
Y |
A |
0.0000 |
|
| 187 |
E |
A |
-3.7980 |
|
| 188 |
K |
A |
-3.6752 |
|
| 189 |
H |
A |
-3.0727 |
|
| 190 |
K |
A |
-3.0707 |
|
| 191 |
V |
A |
-1.7268 |
|
| 192 |
Y |
A |
0.0000 |
|
| 193 |
A |
A |
0.0000 |
|
| 194 |
C |
A |
0.0000 |
|
| 195 |
E |
A |
-0.9646 |
|
| 196 |
V |
A |
0.0000 |
|
| 197 |
T |
A |
-1.2429 |
|
| 198 |
H |
A |
0.0000 |
|
| 199 |
Q |
A |
-1.7176 |
|
| 200 |
G |
A |
-0.5524 |
|
| 201 |
L |
A |
-0.2987 |
|
| 202 |
S |
A |
-0.4846 |
|
| 203 |
S |
A |
-0.4000 |
|
| 204 |
P |
A |
-0.5024 |
|
| 205 |
V |
A |
0.0761 |
|
| 206 |
T |
A |
-0.3974 |
|
| 207 |
K |
A |
-0.3260 |
|
| 208 |
S |
A |
-0.5296 |
|
| 209 |
F |
A |
0.0000 |
|
| 210 |
N |
A |
-2.3110 |
|
| 211 |
R |
A |
-2.8815 |
|
| 212 |
G |
A |
-2.3908 |
|
| 213 |
E |
A |
-2.1807 |
|
| 214 |
C |
A |
-0.3079 |
|