Project name: ppdocksol

Chain sequence(s)	A: GGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDKEGLLSMANAGSNTNGSQFFITTVPTPHLDGKHVVFGQVIKGMGVAKILENVEVKGEKPAKLCVIAECGELKEGDDWGIFPKDGSGDSHPDFPEDADVDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAELLKVKQKIKAQKDKEKAAY
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.2469
• Maximal score value: 1.3516
• Average score: -0.9749
• Total score value: -431.9018

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-1.2134
2	G	A	-1.0703
3	S	A	-1.1804
4	V	A	-0.3792
5	Q	A	-0.6304
6	I	A	0.6887
7	V	A	1.3516
8	Y	A	0.3928
9	K	A	-1.1734
10	P	A	-0.7106
11	V	A	0.0922
12	D	A	-0.9739
13	L	A	0.1678
14	S	A	-0.3032
15	K	A	-0.8312
16	V	A	-0.6343
17	T	A	-0.8258
18	S	A	-0.8984
19	K	A	-1.8046
20	C	A	-0.3772
21	G	A	-0.5222
22	S	A	-0.3902
23	L	A	0.1689
24	G	A	-0.6117
25	N	A	-1.2715
26	I	A	-0.9177
27	H	A	-2.2533
28	H	A	-2.3149
29	K	A	-3.2552
30	P	A	-2.5587
31	G	A	-1.8111
32	G	A	0.0000
33	G	A	-0.3296
34	Q	A	-0.5492
35	V	A	0.2671
36	E	A	-1.3445
37	V	A	-0.3252
38	K	A	-2.2005
39	S	A	-1.9104
40	E	A	-2.8010
41	K	A	-2.2891
42	L	A	-0.2770
43	D	A	-0.8675
44	F	A	-0.1475
45	K	A	-2.2308
46	D	A	-2.9972
47	R	A	-2.7272
48	V	A	-1.1365
49	Q	A	-1.7668
50	S	A	-0.9651
51	K	A	-1.5085
52	I	A	0.2137
53	G	A	-0.3670
54	S	A	-0.3629
55	L	A	-0.1398
56	D	A	-1.6505
57	N	A	-1.5353
58	I	A	-0.0892
59	T	A	0.0000
60	H	A	-0.3915
61	V	A	-0.0885
62	P	A	-0.4843
63	G	A	-0.8184
64	G	A	-0.6966
65	G	A	-1.0730
66	N	A	-1.5678
67	K	A	-2.0583
68	K	A	-1.2507
69	I	A	0.2555
70	E	A	-1.4630
71	T	A	-1.3903
72	H	A	-1.9803
73	K	A	-2.1256
74	L	A	-0.9301
75	T	A	-0.6382
76	F	A	-0.8033
77	R	A	-2.3870
78	E	A	-1.9000
79	N	A	-2.3190
2	S	A	-0.9822
3	H	A	-1.2223
4	P	A	-1.1511
5	S	A	0.0000
6	P	A	-1.2592
7	Q	A	-1.6636
8	A	A	-1.4425
9	K	A	-2.1333
10	P	A	-1.5408
11	S	A	-1.2849
12	N	A	-1.0618
13	P	A	-0.9991
14	S	A	-0.9514
15	N	A	0.0000
16	P	A	-1.2203
17	R	A	-0.9699
18	V	A	0.0000
19	F	A	0.0187
20	F	A	0.0000
21	D	A	0.0000
22	V	A	0.0000
23	D	A	0.0000
24	I	A	-0.6655
25	G	A	-1.4552
26	G	A	0.0000
27	E	A	-2.1945
28	R	A	-1.4718
29	V	A	-0.4235
30	G	A	-0.3583
31	R	A	-0.2599
32	I	A	0.0000
33	V	A	0.0000
34	L	A	0.0000
35	E	A	0.0000
36	L	A	0.0000
37	F	A	0.0000
38	A	A	-1.0655
39	D	A	-1.4412
40	I	A	-0.4623
41	V	A	0.0000
42	P	A	-1.1944
43	K	A	-1.5685
44	T	A	0.0000
45	A	A	0.0000
46	E	A	-1.2322
47	N	A	0.0000
48	F	A	0.0000
49	R	A	-0.9118
50	A	A	0.0000
51	L	A	0.0000
52	C	A	0.0000
53	T	A	-1.1522
54	G	A	0.0000
55	E	A	-2.8194
56	K	A	-2.6357
57	G	A	0.0000
58	I	A	-0.4246
59	G	A	0.0000
60	P	A	-0.6391
61	T	A	-0.7640
62	T	A	-0.9076
63	G	A	-0.7055
64	K	A	-0.9184
65	P	A	0.0000
66	L	A	0.0000
67	H	A	0.0000
68	F	A	0.0000
69	K	A	0.0000
70	G	A	0.0000
71	C	A	0.0000
72	P	A	-0.4041
73	F	A	0.0000
74	H	A	0.0000
75	R	A	-1.5853
76	I	A	0.0000
77	I	A	-1.2149
78	K	A	-2.6412
79	K	A	-2.5475
80	F	A	-0.9050
81	M	A	0.0000
82	I	A	0.0000
83	Q	A	0.0000
84	G	A	0.0000
85	G	A	0.0000
86	D	A	0.0000
87	F	A	0.0000
88	S	A	0.0000
89	N	A	-1.8452
90	Q	A	-1.6516
91	N	A	-1.7167
92	G	A	-1.0908
93	T	A	-0.7115
94	G	A	-1.0560
95	G	A	-1.2325
96	E	A	0.0000
97	S	A	0.0000
98	I	A	0.0000
99	Y	A	-0.3886
100	G	A	-1.2641
101	E	A	-2.6467
102	K	A	-3.0724
103	F	A	0.0000
104	E	A	-2.8532
105	D	A	-2.3072
106	E	A	-1.5516
107	N	A	-1.0078
108	F	A	-0.6690
109	H	A	-0.6716
110	Y	A	-0.8064
111	K	A	-1.5156
112	H	A	0.0000
113	D	A	-1.5851
114	K	A	-1.4176
115	E	A	-1.4536
116	G	A	0.0000
117	L	A	0.0000
118	L	A	0.0000
119	S	A	0.0000
120	M	A	0.0000
121	A	A	-0.3864
122	N	A	-0.9295
123	A	A	-0.4539
124	G	A	-0.7747
125	S	A	-1.3618
126	N	A	-2.2857
127	T	A	-1.8515
128	N	A	0.0000
129	G	A	-1.4773
130	S	A	0.0000
131	Q	A	-0.2864
132	F	A	0.0000
133	F	A	0.0000
134	I	A	0.0000
135	T	A	0.0000
136	T	A	0.0000
137	V	A	-1.0431
138	P	A	-1.1867
139	T	A	0.0000
140	P	A	-1.5346
141	H	A	-1.7736
142	L	A	0.0000
143	D	A	-1.9593
144	G	A	-1.8052
145	K	A	-2.3178
146	H	A	0.0000
147	V	A	0.0000
148	V	A	0.0000
149	F	A	0.0000
150	G	A	0.0000
151	Q	A	0.0000
152	V	A	0.0000
153	I	A	0.0000
154	K	A	-0.6663
155	G	A	0.0000
156	M	A	-0.4062
157	G	A	-0.3539
158	V	A	0.0000
159	A	A	0.0000
160	K	A	-1.0579
161	I	A	0.0173
162	L	A	0.0000
163	E	A	0.0000
164	N	A	-2.0272
165	V	A	-1.5617
166	E	A	-2.6311
167	V	A	-2.0906
168	K	A	-2.6717
169	G	A	-2.0412
170	E	A	-2.4679
171	K	A	-2.6280
172	P	A	-1.7969
173	A	A	-1.3829
174	K	A	-1.3894
175	L	A	-0.7000
176	C	A	0.0000
177	V	A	0.0000
178	I	A	0.0000
179	A	A	0.0000
180	E	A	0.0533
181	C	A	0.0000
182	G	A	0.0000
183	E	A	-1.1797
184	L	A	0.0000
185	K	A	-3.5676
186	E	A	-3.7127
187	G	A	-2.9385
188	D	A	-3.6996
189	D	A	-2.9370
190	W	A	-1.2053
191	G	A	-0.5887
192	I	A	0.0257
193	F	A	0.2634
194	P	A	-0.7536
195	K	A	-1.7946
196	D	A	-1.1204
197	G	A	-1.0238
198	S	A	-0.6285
199	G	A	-0.8084
200	D	A	0.0000
201	S	A	-0.4492
202	H	A	-0.4124
203	P	A	-0.4520
204	D	A	-0.6682
205	F	A	-0.6287
206	P	A	0.0000
207	E	A	-2.4763
208	D	A	-1.4396
209	A	A	-1.7281
210	D	A	-2.4463
211	V	A	-2.5955
212	D	A	-3.4694
213	L	A	-3.3307
214	K	A	-4.1296
215	D	A	-3.9931
216	V	A	0.0000
217	D	A	-2.9972
218	K	A	-2.3948
219	I	A	0.0000
220	L	A	-1.0820
221	L	A	0.0380
222	I	A	0.0000
223	S	A	0.0000
224	E	A	-1.7921
225	D	A	-1.7740
226	L	A	0.0000
227	K	A	-1.6152
228	N	A	-2.1408
229	I	A	-1.2383
230	G	A	0.0000
231	N	A	-1.1626
232	T	A	-0.9402
233	F	A	0.0000
234	F	A	-0.8876
235	K	A	-1.9376
236	S	A	-0.9418
237	Q	A	-1.0596
238	N	A	0.0000
239	W	A	0.0000
240	E	A	-0.8064
241	M	A	-0.6818
242	A	A	0.0000
243	I	A	-0.6356
244	K	A	-1.3813
245	K	A	0.0000
246	Y	A	0.0000
247	T	A	-0.6214
248	K	A	0.0000
249	V	A	0.0000
250	L	A	-0.7646
251	R	A	-1.4971
252	Y	A	0.0000
253	V	A	0.0000
254	E	A	-2.5726
255	G	A	-2.2654
256	S	A	0.0000
257	R	A	-4.1549
258	A	A	-2.1306
259	A	A	-2.4962
260	A	A	-3.4365
261	E	A	-3.8844
262	D	A	-3.6839
263	A	A	-2.6825
264	D	A	-4.2469
265	G	A	-4.0116
266	A	A	-2.4054
267	K	A	-2.6373
268	L	A	0.0000
269	Q	A	-1.3636
270	P	A	-0.7646
271	V	A	0.0000
272	A	A	0.0000
273	L	A	-0.4515
274	S	A	-0.1904
275	C	A	0.0000
276	V	A	0.0000
277	L	A	-0.4377
278	N	A	-0.1940
279	I	A	0.0000
280	G	A	0.0000
281	A	A	0.0000
282	C	A	0.0000
283	K	A	-1.1379
284	L	A	0.0000
285	K	A	-1.1971
286	M	A	-1.2970
287	S	A	-1.1112
288	D	A	-1.1929
289	W	A	-0.8553
290	Q	A	-1.3847
291	G	A	-1.1192
292	A	A	0.0000
293	V	A	0.0000
294	D	A	-1.6082
295	S	A	0.0000
296	C	A	0.0000
297	L	A	-0.8823
298	E	A	-1.8463
299	A	A	0.0000
300	L	A	0.0000
301	E	A	-1.9966
302	I	A	-0.8849
303	D	A	-1.0741
304	P	A	-1.0152
305	S	A	-0.9774
306	N	A	-0.9028
307	T	A	-1.2974
308	K	A	-1.8118
309	A	A	0.0000
310	L	A	0.0000
311	Y	A	-0.8673
312	R	A	-0.9067
313	R	A	-0.8416
314	A	A	0.0000
315	Q	A	-0.3891
316	G	A	0.0000
317	W	A	-0.6994
318	Q	A	0.0000
319	G	A	0.0000
320	L	A	-0.1157
321	K	A	-0.7181
322	E	A	-1.4419
323	Y	A	0.0000
324	D	A	-2.3793
325	Q	A	-1.7687
326	A	A	0.0000
327	L	A	-1.2467
328	A	A	-1.2026
329	D	A	0.0000
330	L	A	0.0000
331	K	A	-2.1693
332	K	A	-1.9265
333	A	A	0.0000
334	Q	A	-2.2961
335	E	A	-2.4108
336	I	A	-0.7324
337	A	A	-1.5506
338	P	A	-2.2682
339	E	A	-2.8676
340	D	A	-2.5673
341	K	A	-2.7030
342	A	A	-1.3505
343	I	A	0.0000
344	Q	A	-1.6481
345	A	A	-0.7124
346	E	A	0.0000
347	L	A	0.0000
348	L	A	-0.1458
349	K	A	0.0000
350	V	A	0.0000
351	K	A	-1.8577
352	Q	A	-1.9463
353	K	A	0.0000
354	I	A	-2.1804
355	K	A	-3.0965
356	A	A	0.0000
357	Q	A	-3.1934
358	K	A	-3.6772
359	D	A	-3.3669
360	K	A	-3.3605
361	E	A	-4.0435
362	K	A	-3.2863
363	A	A	-1.9757
364	A	A	-0.3541
365	Y	A	0.9432