Project name: 2osl:L
Status: done
submitted: 2019-03-20 20:06:29, status changed: 2019-03-20 20:17:58
Settings
|
Chain sequence(s)
|
L: QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.7893
-
Maximal score value
-
2.1172
-
Average score
-
-0.715
-
Total score value
-
-152.3033
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
Q |
L |
-0.9137 |
|
| 2 |
I |
L |
0.4712 |
|
| 3 |
V |
L |
1.3719 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
S |
L |
-0.4132 |
|
| 6 |
Q |
L |
-0.3389 |
|
| 7 |
S |
L |
-0.4387 |
|
| 8 |
P |
L |
0.2700 |
|
| 9 |
A |
L |
0.5439 |
|
| 10 |
I |
L |
1.5604 |
|
| 11 |
L |
L |
0.6153 |
|
| 12 |
S |
L |
-0.3063 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-1.8713 |
|
| 15 |
P |
L |
-2.1903 |
|
| 16 |
G |
L |
-2.2038 |
|
| 17 |
E |
L |
-2.9603 |
|
| 18 |
K |
L |
-3.0506 |
|
| 19 |
V |
L |
-1.3182 |
|
| 20 |
T |
L |
-0.3802 |
|
| 21 |
M |
L |
0.0000 |
|
| 22 |
T |
L |
-0.7297 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-1.9370 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.2795 |
|
| 27 |
S |
L |
-0.5045 |
|
| 28 |
S |
L |
-0.5860 |
|
| 29 |
V |
L |
0.0000 |
|
| 30 |
S |
L |
0.4213 |
|
| 31 |
Y |
L |
1.3517 |
|
| 32 |
I |
L |
0.0000 |
|
| 33 |
H |
L |
0.8299 |
|
| 34 |
W |
L |
0.0000 |
|
| 35 |
F |
L |
0.0475 |
|
| 36 |
Q |
L |
0.0000 |
|
| 37 |
Q |
L |
-1.1250 |
|
| 38 |
K |
L |
-1.6944 |
|
| 39 |
P |
L |
-1.2101 |
|
| 40 |
G |
L |
-0.8839 |
|
| 41 |
S |
L |
-0.9916 |
|
| 42 |
S |
L |
-0.9594 |
|
| 43 |
P |
L |
-1.0790 |
|
| 44 |
K |
L |
-1.4811 |
|
| 45 |
P |
L |
-0.4625 |
|
| 46 |
W |
L |
-0.1711 |
|
| 47 |
I |
L |
0.0000 |
|
| 48 |
Y |
L |
0.7406 |
|
| 49 |
A |
L |
0.5958 |
|
| 50 |
T |
L |
0.1254 |
|
| 51 |
S |
L |
-0.4219 |
|
| 52 |
N |
L |
-0.8122 |
|
| 53 |
L |
L |
0.3776 |
|
| 54 |
A |
L |
-0.1589 |
|
| 55 |
S |
L |
-0.4194 |
|
| 56 |
G |
L |
-0.2729 |
|
| 57 |
V |
L |
0.0000 |
|
| 58 |
P |
L |
0.6480 |
|
| 59 |
V |
L |
1.4028 |
|
| 60 |
R |
L |
-0.3761 |
|
| 61 |
F |
L |
0.0000 |
|
| 62 |
S |
L |
-0.0243 |
|
| 63 |
G |
L |
0.0000 |
|
| 64 |
S |
L |
-0.5247 |
|
| 65 |
G |
L |
-0.6518 |
|
| 66 |
S |
L |
-0.5551 |
|
| 67 |
G |
L |
-0.5873 |
|
| 68 |
T |
L |
-0.9281 |
|
| 69 |
S |
L |
-1.1500 |
|
| 70 |
Y |
L |
0.0000 |
|
| 71 |
S |
L |
-0.6198 |
|
| 72 |
L |
L |
0.0000 |
|
| 73 |
T |
L |
-0.6853 |
|
| 74 |
I |
L |
0.0000 |
|
| 75 |
S |
L |
-1.8409 |
|
| 76 |
R |
L |
-3.0324 |
|
| 77 |
V |
L |
0.0000 |
|
| 78 |
E |
L |
-2.8610 |
|
| 79 |
A |
L |
-2.4958 |
|
| 80 |
E |
L |
-2.9408 |
|
| 81 |
D |
L |
0.0000 |
|
| 82 |
A |
L |
-1.8302 |
|
| 83 |
A |
L |
0.0000 |
|
| 84 |
T |
L |
0.0000 |
|
| 85 |
Y |
L |
0.0000 |
|
| 86 |
Y |
L |
0.2357 |
|
| 87 |
C |
L |
0.0000 |
|
| 88 |
Q |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
W |
L |
1.2804 |
|
| 91 |
T |
L |
0.2345 |
|
| 92 |
S |
L |
-0.7046 |
|
| 93 |
N |
L |
-1.4412 |
|
| 94 |
P |
L |
-1.1219 |
|
| 95 |
P |
L |
0.1471 |
|
| 96 |
T |
L |
0.9544 |
|
| 97 |
F |
L |
2.1172 |
|
| 98 |
G |
L |
0.7070 |
|
| 99 |
G |
L |
-0.0439 |
|
| 100 |
G |
L |
0.0086 |
|
| 101 |
T |
L |
0.0000 |
|
| 102 |
K |
L |
-0.4228 |
|
| 103 |
L |
L |
0.0000 |
|
| 104 |
E |
L |
-0.9287 |
|
| 105 |
I |
L |
0.0000 |
|
| 106 |
K |
L |
-1.6128 |
|
| 107 |
R |
L |
-1.0956 |
|
| 108 |
T |
L |
-0.0405 |
|
| 109 |
V |
L |
0.7391 |
|
| 110 |
A |
L |
-0.0723 |
|
| 111 |
A |
L |
-0.2214 |
|
| 112 |
P |
L |
0.0000 |
|
| 113 |
S |
L |
-0.1400 |
|
| 114 |
V |
L |
0.0000 |
|
| 115 |
F |
L |
1.0444 |
|
| 116 |
I |
L |
0.9693 |
|
| 117 |
F |
L |
1.2827 |
|
| 118 |
P |
L |
0.0431 |
|
| 119 |
P |
L |
-0.8013 |
|
| 120 |
S |
L |
-1.8149 |
|
| 121 |
D |
L |
-3.2945 |
|
| 122 |
E |
L |
-3.5185 |
|
| 123 |
Q |
L |
-2.5313 |
|
| 124 |
L |
L |
-2.2422 |
|
| 125 |
K |
L |
-3.0959 |
|
| 126 |
S |
L |
-1.9263 |
|
| 127 |
G |
L |
-1.2894 |
|
| 128 |
T |
L |
-1.1072 |
|
| 129 |
A |
L |
0.0000 |
|
| 130 |
S |
L |
0.0200 |
|
| 131 |
V |
L |
0.0000 |
|
| 132 |
V |
L |
0.5801 |
|
| 133 |
C |
L |
0.0000 |
|
| 134 |
L |
L |
0.3904 |
|
| 135 |
L |
L |
0.0000 |
|
| 136 |
N |
L |
-0.6813 |
|
| 137 |
N |
L |
-1.3755 |
|
| 138 |
F |
L |
0.0000 |
|
| 139 |
Y |
L |
0.0000 |
|
| 140 |
P |
L |
-1.6341 |
|
| 141 |
R |
L |
-2.8810 |
|
| 142 |
E |
L |
-3.0885 |
|
| 143 |
A |
L |
-2.3127 |
|
| 144 |
K |
L |
-2.4550 |
|
| 145 |
V |
L |
-1.2778 |
|
| 146 |
Q |
L |
-0.5644 |
|
| 147 |
W |
L |
0.0000 |
|
| 148 |
K |
L |
-0.5070 |
|
| 149 |
V |
L |
0.0000 |
|
| 150 |
D |
L |
-2.1333 |
|
| 151 |
N |
L |
-1.6599 |
|
| 152 |
A |
L |
-0.2922 |
|
| 153 |
L |
L |
0.6728 |
|
| 154 |
Q |
L |
-0.4955 |
|
| 155 |
S |
L |
-0.9123 |
|
| 156 |
G |
L |
-1.5062 |
|
| 157 |
N |
L |
-1.9154 |
|
| 158 |
S |
L |
-1.8962 |
|
| 159 |
Q |
L |
-2.5228 |
|
| 160 |
E |
L |
-2.3501 |
|
| 161 |
S |
L |
-1.3533 |
|
| 162 |
V |
L |
-0.6909 |
|
| 163 |
T |
L |
-1.0665 |
|
| 164 |
E |
L |
-2.3088 |
|
| 165 |
Q |
L |
0.0000 |
|
| 166 |
D |
L |
-2.5535 |
|
| 167 |
S |
L |
-2.6646 |
|
| 168 |
K |
L |
-2.8620 |
|
| 169 |
D |
L |
-2.0258 |
|
| 170 |
S |
L |
0.0000 |
|
| 171 |
T |
L |
0.0000 |
|
| 172 |
Y |
L |
0.0000 |
|
| 173 |
S |
L |
-1.0248 |
|
| 174 |
L |
L |
0.0000 |
|
| 175 |
S |
L |
-0.5285 |
|
| 176 |
S |
L |
0.0000 |
|
| 177 |
T |
L |
-0.6604 |
|
| 178 |
L |
L |
0.0000 |
|
| 179 |
T |
L |
-0.4997 |
|
| 180 |
L |
L |
-0.7657 |
|
| 181 |
S |
L |
-1.0780 |
|
| 182 |
K |
L |
-2.1199 |
|
| 183 |
A |
L |
-1.8565 |
|
| 184 |
D |
L |
-2.5921 |
|
| 185 |
Y |
L |
0.0000 |
|
| 186 |
E |
L |
-3.7893 |
|
| 187 |
K |
L |
-3.7408 |
|
| 188 |
H |
L |
-3.1925 |
|
| 189 |
K |
L |
-3.3840 |
|
| 190 |
V |
L |
-1.7299 |
|
| 191 |
Y |
L |
0.0000 |
|
| 192 |
A |
L |
0.0000 |
|
| 193 |
C |
L |
0.0000 |
|
| 194 |
E |
L |
-0.8189 |
|
| 195 |
V |
L |
0.0000 |
|
| 196 |
T |
L |
-1.2123 |
|
| 197 |
H |
L |
0.0000 |
|
| 198 |
Q |
L |
-1.6860 |
|
| 199 |
G |
L |
-0.3686 |
|
| 200 |
L |
L |
-0.2013 |
|
| 201 |
S |
L |
-0.4321 |
|
| 202 |
S |
L |
-0.3987 |
|
| 203 |
P |
L |
-0.5344 |
|
| 204 |
V |
L |
-0.0022 |
|
| 205 |
T |
L |
-0.4642 |
|
| 206 |
K |
L |
-0.5807 |
|
| 207 |
S |
L |
-0.4008 |
|
| 208 |
F |
L |
-0.6740 |
|
| 209 |
N |
L |
-1.7878 |
|
| 210 |
R |
L |
-2.6129 |
|
| 211 |
G |
L |
-2.2161 |
|
| 212 |
E |
L |
-2.1583 |
|
| 213 |
C |
L |
-0.4690 |
|