Project name: 3gkw:L
Status: done
submitted: 2019-03-20 20:09:42, status changed: 2019-03-20 20:15:47
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCRSSQNIVHSNGNTYLDWYQQTPGKAPKLLIYKVSNRFSGVPSRFSGSGSGTDFTFTISSLQPEDIATYYCFQYSHVPWTFGQGTKLQITREVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYCEVTHQGLSSPVTK
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.5948
-
Maximal score value
-
1.718
-
Average score
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-0.7767
-
Total score value
-
-154.5676
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-1.9488 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.7263 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.9821 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.5529 |
|
| 8 |
P |
L |
-0.6268 |
|
| 9 |
S |
L |
-0.9093 |
|
| 10 |
S |
L |
-0.9780 |
|
| 11 |
L |
L |
-0.5521 |
|
| 12 |
S |
L |
-0.6198 |
|
| 13 |
A |
L |
-0.7253 |
|
| 14 |
S |
L |
-0.7853 |
|
| 15 |
V |
L |
-0.2304 |
|
| 16 |
G |
L |
-0.9850 |
|
| 17 |
D |
L |
-1.9383 |
|
| 18 |
R |
L |
-2.4357 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6632 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.5980 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.0119 |
|
| 25 |
S |
L |
0.0000 |
|
| 26 |
S |
L |
-2.0440 |
|
| 27 |
Q |
L |
-2.4605 |
|
| 27A |
N |
L |
-1.9489 |
|
| 27B |
I |
L |
0.0000 |
|
| 27C |
V |
L |
-0.4809 |
|
| 27D |
H |
L |
-0.9831 |
|
| 27E |
S |
L |
-1.0078 |
|
| 28 |
N |
L |
-1.7006 |
|
| 29 |
G |
L |
-1.2389 |
|
| 30 |
N |
L |
-1.0302 |
|
| 31 |
T |
L |
-0.5093 |
|
| 32 |
Y |
L |
0.1572 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
D |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.0108 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.4231 |
|
| 39 |
T |
L |
-1.7439 |
|
| 40 |
P |
L |
-1.5401 |
|
| 41 |
G |
L |
-1.6638 |
|
| 42 |
K |
L |
-2.2810 |
|
| 43 |
A |
L |
-1.4207 |
|
| 44 |
P |
L |
-1.4238 |
|
| 45 |
K |
L |
-1.6544 |
|
| 46 |
L |
L |
-0.2360 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.1789 |
|
| 50 |
K |
L |
-0.4697 |
|
| 51 |
V |
L |
-0.5098 |
|
| 52 |
S |
L |
-0.6772 |
|
| 53 |
N |
L |
-0.8117 |
|
| 54 |
R |
L |
-0.8599 |
|
| 55 |
F |
L |
0.3679 |
|
| 56 |
S |
L |
-0.0513 |
|
| 57 |
G |
L |
-0.3701 |
|
| 58 |
V |
L |
-0.2650 |
|
| 59 |
P |
L |
-0.4154 |
|
| 60 |
S |
L |
-0.5569 |
|
| 61 |
R |
L |
-0.9128 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.4707 |
|
| 64 |
G |
L |
0.0000 |
|
| 65 |
S |
L |
-0.6936 |
|
| 66 |
G |
L |
-0.9634 |
|
| 67 |
S |
L |
-0.9028 |
|
| 68 |
G |
L |
-1.1531 |
|
| 69 |
T |
L |
-1.6873 |
|
| 70 |
D |
L |
-1.9651 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.5886 |
|
| 73 |
F |
L |
0.0000 |
|
| 74 |
T |
L |
-0.5868 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.3566 |
|
| 77 |
S |
L |
-1.3290 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-1.2639 |
|
| 80 |
P |
L |
-2.1173 |
|
| 81 |
E |
L |
-2.7413 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
I |
L |
0.0000 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
T |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.1638 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
F |
L |
1.1264 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
Y |
L |
0.9853 |
|
| 92 |
S |
L |
0.1169 |
|
| 93 |
H |
L |
-0.0510 |
|
| 94 |
V |
L |
1.2943 |
|
| 95 |
P |
L |
0.5996 |
|
| 96 |
W |
L |
1.5339 |
|
| 97 |
T |
L |
0.8665 |
|
| 98 |
F |
L |
1.3565 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
Q |
L |
-0.9954 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.9183 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
Q |
L |
-1.3604 |
|
| 106 |
I |
L |
0.0000 |
|
| 107 |
T |
L |
-0.5293 |
|
| 108 |
R |
L |
-1.0286 |
|
| 109 |
E |
L |
-1.6011 |
|
| 110 |
V |
L |
-0.3125 |
|
| 111 |
A |
L |
-0.5060 |
|
| 112 |
A |
L |
-0.4388 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
-0.1734 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.4064 |
|
| 117 |
I |
L |
1.4349 |
|
| 118 |
F |
L |
1.7180 |
|
| 119 |
P |
L |
0.5752 |
|
| 120 |
P |
L |
-0.5007 |
|
| 121 |
S |
L |
-1.7995 |
|
| 122 |
D |
L |
-3.2796 |
|
| 123 |
E |
L |
-3.5948 |
|
| 124 |
Q |
L |
-2.9367 |
|
| 125 |
L |
L |
-2.5938 |
|
| 126 |
K |
L |
-3.1162 |
|
| 127 |
S |
L |
-2.1508 |
|
| 128 |
G |
L |
-1.3165 |
|
| 129 |
T |
L |
-1.1902 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.1786 |
|
| 132 |
V |
L |
0.9825 |
|
| 133 |
V |
L |
0.9271 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.7509 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.6176 |
|
| 138 |
N |
L |
-1.6417 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.8495 |
|
| 142 |
R |
L |
-3.0865 |
|
| 143 |
E |
L |
-3.2136 |
|
| 144 |
A |
L |
-2.2288 |
|
| 145 |
K |
L |
-2.4560 |
|
| 146 |
V |
L |
-1.4549 |
|
| 147 |
Q |
L |
-1.9175 |
|
| 148 |
W |
L |
-1.1582 |
|
| 155 |
Q |
L |
-1.6779 |
|
| 156 |
S |
L |
-1.4425 |
|
| 157 |
G |
L |
-1.1886 |
|
| 158 |
N |
L |
-1.1394 |
|
| 159 |
S |
L |
-1.6235 |
|
| 160 |
Q |
L |
-2.3374 |
|
| 161 |
E |
L |
-2.3434 |
|
| 162 |
S |
L |
-1.1651 |
|
| 163 |
V |
L |
-0.8126 |
|
| 164 |
T |
L |
-1.2959 |
|
| 165 |
E |
L |
-2.3585 |
|
| 166 |
Q |
L |
0.0000 |
|
| 167 |
D |
L |
-2.9425 |
|
| 168 |
S |
L |
-2.8992 |
|
| 169 |
K |
L |
-3.2506 |
|
| 170 |
D |
L |
-2.9068 |
|
| 171 |
S |
L |
0.0000 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
-1.5445 |
|
| 174 |
S |
L |
-1.0434 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
-0.5121 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5149 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.1145 |
|
| 181 |
L |
L |
-0.2839 |
|
| 182 |
S |
L |
-0.9432 |
|
| 183 |
K |
L |
-2.0022 |
|
| 184 |
A |
L |
-1.4609 |
|
| 185 |
D |
L |
-1.6364 |
|
| 186 |
Y |
L |
-0.3228 |
|
| 194 |
C |
L |
-0.6051 |
|
| 195 |
E |
L |
-1.8477 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.4124 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.6936 |
|
| 200 |
G |
L |
-0.5946 |
|
| 201 |
L |
L |
-0.2368 |
|
| 202 |
S |
L |
-0.4710 |
|
| 203 |
S |
L |
-0.4072 |
|
| 204 |
P |
L |
-0.6723 |
|
| 205 |
V |
L |
-0.4216 |
|
| 206 |
T |
L |
-1.1024 |
|
| 207 |
K |
L |
-1.2744 |
|