| Chain sequence(s) |
A: MSGAPSATQPATAETQHIADQVRSQLEEKYNKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKSLTLSNYQTNKAKHDELTYF B: GAPSATQPATAETQHIADQVRSQLEEKYNKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKSLTLSNYQTNKAKHDELTYF |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 2 | M | A | 0.9056 | |
| 3 | S | A | 0.1646 | |
| 4 | G | A | -0.0594 | |
| 5 | A | A | -0.1201 | |
| 6 | P | A | 0.0343 | |
| 7 | S | A | -0.1672 | |
| 8 | A | A | -0.2095 | |
| 9 | T | A | -0.5825 | |
| 10 | Q | A | -0.4499 | |
| 11 | P | A | -0.2965 | |
| 12 | A | A | -0.5381 | |
| 13 | T | A | -0.8168 | |
| 14 | A | A | -1.1778 | |
| 15 | E | A | -2.5915 | |
| 16 | T | A | 0.0000 | |
| 17 | Q | A | -2.1225 | |
| 18 | H | A | -3.0084 | |
| 19 | I | A | 0.0000 | |
| 20 | A | A | 0.0000 | |
| 21 | D | A | -3.3990 | |
| 22 | Q | A | -2.9306 | |
| 23 | V | A | 0.0000 | |
| 24 | R | A | -2.5181 | |
| 25 | S | A | -2.6780 | |
| 26 | Q | A | -2.3600 | |
| 27 | L | A | 0.0000 | |
| 28 | E | A | 0.0000 | |
| 29 | E | A | -3.7299 | |
| 30 | K | A | -2.6372 | |
| 31 | Y | A | -2.1822 | |
| 32 | N | A | -3.1500 | |
| 33 | K | A | -3.6249 | |
| 34 | K | A | -3.1596 | |
| 35 | F | A | 0.0000 | |
| 36 | P | A | -0.8610 | |
| 37 | V | A | -0.3196 | |
| 38 | F | A | 0.0000 | |
| 39 | K | A | -1.3469 | |
| 40 | A | A | 0.0000 | |
| 41 | V | A | -0.1660 | |
| 42 | S | A | -0.1429 | |
| 43 | F | A | -0.0554 | |
| 44 | K | A | -0.2326 | |
| 45 | S | A | -0.1756 | |
| 46 | Q | A | 0.1487 | |
| 47 | V | A | 0.4911 | |
| 48 | V | A | 0.4226 | |
| 49 | A | A | 0.8741 | |
| 50 | G | A | 0.0000 | |
| 51 | T | A | 0.7638 | |
| 52 | N | A | 0.0000 | |
| 53 | Y | A | 0.4499 | |
| 54 | F | A | 0.0000 | |
| 55 | I | A | 0.0000 | |
| 56 | K | A | 0.0000 | |
| 57 | V | A | 0.0000 | |
| 58 | H | A | -1.7537 | |
| 59 | V | A | 0.0000 | |
| 60 | G | A | -2.0519 | |
| 61 | D | A | -3.2466 | |
| 62 | E | A | -4.1152 | |
| 63 | D | A | -3.9937 | |
| 64 | F | A | 0.0000 | |
| 65 | V | A | 0.0000 | |
| 66 | H | A | 0.0000 | |
| 67 | L | A | 0.0000 | |
| 68 | R | A | -0.1733 | |
| 69 | V | A | 0.0000 | |
| 70 | F | A | 0.4859 | |
| 71 | Q | A | -0.0752 | |
| 72 | S | A | -0.3243 | |
| 73 | L | A | -0.0820 | |
| 74 | P | A | -0.9651 | |
| 75 | H | A | -2.0269 | |
| 76 | E | A | -2.7799 | |
| 77 | N | A | -2.1374 | |
| 78 | K | A | -2.6273 | |
| 79 | S | A | -1.0392 | |
| 80 | L | A | -0.2160 | |
| 81 | T | A | 0.0302 | |
| 82 | L | A | -0.0202 | |
| 83 | S | A | -0.1435 | |
| 84 | N | A | -0.5351 | |
| 85 | Y | A | -0.3572 | |
| 86 | Q | A | -0.9882 | |
| 87 | T | A | -1.3866 | |
| 88 | N | A | -2.3319 | |
| 89 | K | A | -2.7268 | |
| 90 | A | A | -2.7967 | |
| 91 | K | A | -2.9648 | |
| 92 | H | A | -2.3848 | |
| 93 | D | A | -2.3495 | |
| 94 | E | A | -2.4342 | |
| 95 | L | A | 0.0000 | |
| 96 | T | A | 0.0113 | |
| 97 | Y | A | 1.2076 | |
| 98 | F | A | 0.8950 | |
| 4 | G | B | 0.3413 | |
| 5 | A | B | 0.2224 | |
| 6 | P | B | 0.2354 | |
| 7 | S | B | -0.1821 | |
| 8 | A | B | -0.3494 | |
| 9 | T | B | -0.8101 | |
| 10 | Q | B | -0.9199 | |
| 11 | P | B | -0.5053 | |
| 12 | A | B | -0.6275 | |
| 13 | T | B | -0.8223 | |
| 14 | A | B | -1.1148 | |
| 15 | E | B | -2.4721 | |
| 16 | T | B | 0.0000 | |
| 17 | Q | B | -1.9333 | |
| 18 | H | B | -2.5774 | |
| 19 | I | B | -1.5660 | |
| 20 | A | B | 0.0000 | |
| 21 | D | B | -2.9619 | |
| 22 | Q | B | -2.4189 | |
| 23 | V | B | 0.0000 | |
| 24 | R | B | -2.9984 | |
| 25 | S | B | -3.2263 | |
| 26 | Q | B | -3.2383 | |
| 27 | L | B | 0.0000 | |
| 28 | E | B | -4.5179 | |
| 29 | E | B | -4.3781 | |
| 30 | K | B | -3.4957 | |
| 31 | Y | B | -2.4446 | |
| 32 | N | B | -3.6202 | |
| 33 | K | B | -3.3294 | |
| 34 | K | B | -2.9638 | |
| 35 | F | B | -1.2115 | |
| 36 | P | B | -0.5281 | |
| 37 | V | B | -0.3892 | |
| 38 | F | B | 0.0000 | |
| 39 | K | B | -1.4507 | |
| 40 | A | B | 0.0000 | |
| 41 | V | B | -0.1129 | |
| 42 | S | B | -0.2545 | |
| 43 | F | B | -0.1826 | |
| 44 | K | B | -0.5787 | |
| 45 | S | B | 0.0424 | |
| 46 | Q | B | 0.7088 | |
| 47 | V | B | 1.6024 | |
| 48 | V | B | 1.0713 | |
| 49 | A | B | 0.9515 | |
| 50 | G | B | 0.3753 | |
| 51 | T | B | 0.2516 | |
| 52 | N | B | 0.0000 | |
| 53 | Y | B | 0.2083 | |
| 54 | F | B | 0.0000 | |
| 55 | I | B | 0.0000 | |
| 56 | K | B | 0.0000 | |
| 57 | V | B | 0.0000 | |
| 58 | H | B | -1.7569 | |
| 59 | V | B | 0.0000 | |
| 60 | G | B | 0.0000 | |
| 61 | D | B | -3.3576 | |
| 62 | E | B | -4.1426 | |
| 63 | D | B | -3.9029 | |
| 64 | F | B | 0.0000 | |
| 65 | V | B | 0.0000 | |
| 66 | H | B | 0.0000 | |
| 67 | L | B | 0.0000 | |
| 68 | R | B | -0.3006 | |
| 69 | V | B | 0.0000 | |
| 70 | F | B | 0.2649 | |
| 71 | Q | B | -0.4453 | |
| 72 | S | B | -0.3284 | |
| 73 | L | B | -0.0530 | |
| 74 | P | B | -0.9448 | |
| 75 | H | B | -2.0023 | |
| 76 | E | B | -2.7821 | |
| 77 | N | B | -2.1278 | |
| 78 | K | B | -2.8940 | |
| 79 | S | B | -1.3112 | |
| 80 | L | B | -0.5608 | |
| 81 | T | B | -0.1788 | |
| 82 | L | B | -0.4231 | |
| 83 | S | B | -0.3383 | |
| 84 | N | B | -0.8018 | |
| 85 | Y | B | -0.4193 | |
| 86 | Q | B | -0.9870 | |
| 87 | T | B | -1.1858 | |
| 88 | N | B | -2.4215 | |
| 89 | K | B | -2.7428 | |
| 90 | A | B | -2.9818 | |
| 91 | K | B | -3.7342 | |
| 92 | H | B | -2.7084 | |
| 93 | D | B | -2.7623 | |
| 94 | E | B | -2.6019 | |
| 95 | L | B | 0.0000 | |
| 96 | T | B | 0.0126 | |
| 97 | Y | B | 1.2186 | |
| 98 | F | B | 0.8908 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine