Project name: mab6

Chain sequence(s)	H: QVQLVQSGAEVKKPGSSVKVSCKASWAQMYFYGISWVRQAPGQGLEWMGGIIPIFDTGNSAQSFQGRVTITADESTSTAYMELSSLRSEQTAVYYCTASPRLVQLNPSLTAYYDMQVWGQGTMVTVS; L: SVLTQPPSVSAAPGQKVTISCSGSSSNIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAWVFGGGTKLTVLRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.7163
• Maximal score value: 2.1095
• Average score: -0.5726
• Total score value: -136.2893

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-0.9875
2	V	H	-0.4755
3	Q	H	-1.0369
4	L	H	0.0000
5	V	H	-0.4649
6	Q	H	0.0000
7	S	H	-0.8012
8	G	H	-0.6943
9	A	H	-0.0677
10	E	H	-0.3634
11	V	H	0.7719
12	K	H	-0.9535
13	K	H	-2.0536
14	P	H	-1.9334
15	G	H	-1.5313
16	S	H	-1.2340
17	S	H	-1.4909
18	V	H	0.0000
19	K	H	-2.0891
20	V	H	0.0000
21	S	H	-0.7638
22	C	H	0.0000
23	K	H	-1.5425
24	A	H	-0.8402
25	S	H	-0.4065
26	W	H	0.3781
27	A	H	-0.2970
28	Q	H	-0.9923
29	M	H	0.0000
30	Y	H	1.0126
31	F	H	2.1095
32	Y	H	1.1190
33	G	H	0.0000
34	I	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.4109
40	A	H	0.0000
41	P	H	-0.8958
42	G	H	-0.9060
43	Q	H	-1.0907
44	G	H	-0.6850
45	L	H	0.0000
46	E	H	-0.4059
47	W	H	0.0000
48	M	H	0.0000
49	G	H	0.0000
50	G	H	-0.5594
51	I	H	0.0000
52	I	H	0.5235
52A	P	H	0.0000
53	I	H	1.1970
54	F	H	1.5799
55	D	H	-1.0745
56	T	H	-0.5253
57	G	H	-1.0114
58	N	H	-1.2981
59	S	H	-1.3088
60	A	H	-1.0431
61	Q	H	-1.7142
62	S	H	-1.2735
63	F	H	0.0000
64	Q	H	-2.3692
65	G	H	-1.8843
66	R	H	-2.1296
67	V	H	-1.4004
68	T	H	-1.0238
69	I	H	-0.4857
70	T	H	-0.6926
71	A	H	-1.1659
72	D	H	-1.8996
73	E	H	-2.4664
74	S	H	-1.4123
75	T	H	-1.4317
76	S	H	-1.5441
77	T	H	-1.4017
78	A	H	0.0000
79	Y	H	-0.5709
80	M	H	0.0000
81	E	H	-1.6360
82	L	H	0.0000
82A	S	H	-1.4227
82B	S	H	-1.3722
82C	L	H	0.0000
83	R	H	-2.7163
84	S	H	-2.2429
85	E	H	-2.5232
86	Q	H	-1.5924
87	T	H	-0.7446
88	A	H	0.0000
89	V	H	0.3068
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	T	H	0.0000
94	A	H	0.0000
95	S	H	0.0000
96	P	H	0.6794
97	R	H	0.9511
98	L	H	1.6410
99	V	H	1.4863
100	Q	H	-0.5812
100A	L	H	-0.2828
100B	N	H	-1.2549
100C	P	H	-0.9571
100D	S	H	-0.7206
100E	L	H	-0.2555
100F	T	H	-0.3377
100G	A	H	0.0000
100H	Y	H	0.1898
100I	Y	H	0.0000
100J	D	H	0.0000
100K	M	H	0.0000
101	Q	H	-0.4159
102	V	H	-0.3251
103	W	H	-0.3937
104	G	H	0.0000
105	Q	H	-1.0962
106	G	H	-0.4495
107	T	H	0.0000
108	M	H	0.3797
109	V	H	0.0000
110	T	H	-0.2636
111	V	H	0.0000
112	S	H	-1.0739
2	S	L	0.1331
3	V	L	1.0202
4	L	L	0.0000
5	T	L	-0.0520
6	Q	L	0.0000
7	P	L	-0.5833
8	P	L	-0.8932
10	S	L	-1.0007
11	V	L	-0.4058
12	S	L	-0.6274
13	A	L	0.0000
14	A	L	-1.0018
15	P	L	-1.4989
16	G	L	-1.7541
17	Q	L	-2.2716
18	K	L	-2.4809
19	V	L	0.0000
20	T	L	-0.5055
21	I	L	0.0000
22	S	L	-0.2975
23	C	L	0.0000
24	S	L	-0.2415
25	G	L	-0.2239
26	S	L	-0.6561
27	S	L	-0.8867
28	S	L	-0.6759
29	N	L	0.0000
30	I	L	0.0000
30A	G	L	-1.2016
30B	N	L	-1.4270
31	N	L	-0.5113
32	Y	L	0.2115
33	V	L	0.0000
34	S	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	-0.8171
39	L	L	-0.5820
40	P	L	-0.5429
41	G	L	-0.4409
42	T	L	-0.5906
43	A	L	-0.5800
44	P	L	0.0000
45	K	L	-1.1056
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	-0.6633
50	D	L	-0.8705
51	N	L	-1.2655
52	N	L	-2.4130
53	K	L	-2.6870
54	R	L	-2.3415
55	P	L	-1.0898
56	S	L	-0.7955
57	G	L	-0.9634
58	I	L	0.0000
59	P	L	-1.4638
60	D	L	-2.2755
61	R	L	-1.6525
62	F	L	0.0000
63	S	L	-1.5667
64	G	L	-1.3511
65	S	L	-1.1831
66	K	L	-0.9940
67	S	L	-0.7749
68	G	L	-1.0272
69	T	L	-0.9219
70	S	L	-0.6599
71	A	L	0.0000
72	T	L	-0.5546
73	L	L	0.0000
74	G	L	-0.6306
75	I	L	0.0000
76	T	L	-1.8200
77	G	L	-1.7350
78	L	L	0.0000
79	Q	L	-1.9386
80	T	L	-1.4342
81	G	L	-1.3575
82	D	L	0.0000
83	E	L	-2.4621
84	A	L	0.0000
85	D	L	-1.4194
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	G	L	0.0000
90	T	L	0.0000
91	W	L	0.0000
92	D	L	0.0000
93	S	L	-0.3545
94	S	L	0.0012
95	L	L	0.1527
95A	S	L	-0.0309
95B	A	L	0.0000
96	W	L	0.0000
97	V	L	0.0000
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-0.5740
101	G	L	-0.9358
102	T	L	0.0000
103	K	L	-2.2641
104	L	L	0.0000
105	T	L	-0.9479
106	V	L	-0.8975
107	L	L	-0.0414
108	R	L	-1.3861
109	T	L	-0.7752