Project name: mab2

Chain sequence(s)	H: QVQLVQSGAEVKKPGSSVKVSCKASGGTFWFGAFTWVRQAPGQGLEWMGGIIPIFGLTNLAQNFQGRVTITADESTSTVYMELSSLRSEDTAVYYCARSSRIYDLNPSLTAYYDMQVWGQGTMVTVS; L: SVLTQPPSVSAAPGQKVTISCSGSSSDIGNNYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEADYYCGTWDSSLSAWVFGGGTKLTVLRT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.8271
• Maximal score value: 2.4986
• Average score: -0.506
• Total score value: -120.4288

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5249
2	V	H	-1.0170
3	Q	H	-1.5665
4	L	H	0.0000
5	V	H	-0.4392
6	Q	H	0.0000
7	S	H	-0.7585
8	G	H	-0.6661
9	A	H	-0.0352
10	E	H	-0.2677
11	V	H	0.8117
12	K	H	-0.9581
13	K	H	-2.0919
14	P	H	-2.0140
15	G	H	-1.5380
16	S	H	-1.2321
17	S	H	-1.4295
18	V	H	0.0000
19	K	H	-2.2288
20	V	H	0.0000
21	S	H	-0.8005
22	C	H	0.0000
23	K	H	-1.5709
24	A	H	0.0000
25	S	H	-0.9892
26	G	H	-1.1842
27	G	H	-0.5889
28	T	H	0.4163
29	F	H	0.4813
30	W	H	1.5253
31	F	H	2.4986
32	G	H	0.0000
33	A	H	0.0000
34	F	H	0.0000
35	T	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6632
40	A	H	-1.0427
41	P	H	-1.0999
42	G	H	-1.2371
43	Q	H	-1.8039
44	G	H	-1.2706
45	L	H	0.0000
46	E	H	-0.7088
47	W	H	0.0000
48	M	H	0.0000
49	G	H	0.0000
50	G	H	0.0318
51	I	H	0.0000
52	I	H	0.0000
52A	P	H	0.2964
53	I	H	1.3516
54	F	H	2.2248
55	G	H	1.0460
56	L	H	1.7173
57	T	H	0.4921
58	N	H	-0.5423
59	L	H	-0.8913
60	A	H	-1.1998
61	Q	H	-2.1314
62	N	H	-2.2377
63	F	H	0.0000
64	Q	H	-2.2963
65	G	H	-1.5467
66	R	H	-1.3763
67	V	H	0.0000
68	T	H	-0.9842
69	I	H	0.0000
70	T	H	-0.4997
71	A	H	-1.2887
72	D	H	-2.4480
73	E	H	-2.3396
74	S	H	-1.4935
75	T	H	-1.3935
76	S	H	-1.5931
77	T	H	0.0000
78	V	H	0.0000
79	Y	H	-0.8554
80	M	H	0.0000
81	E	H	-1.8142
82	L	H	0.0000
82A	S	H	-1.1738
82B	S	H	-1.0691
82C	L	H	0.0000
83	R	H	-2.8271
84	S	H	-2.2820
85	E	H	-2.5229
86	D	H	0.0000
87	T	H	-0.7091
88	A	H	0.0000
89	V	H	0.2836
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	S	H	0.0562
96	S	H	0.8853
97	R	H	1.0745
98	I	H	2.0338
99	Y	H	1.4827
100	D	H	-0.9334
100A	L	H	-0.3795
100B	N	H	-1.2584
100C	P	H	-0.9552
100D	S	H	-0.6213
100E	L	H	-0.0677
100F	T	H	-0.2049
100G	A	H	0.0000
100H	Y	H	0.3306
100I	Y	H	0.4224
100J	D	H	0.0000
100K	M	H	0.0000
101	Q	H	-0.4863
102	V	H	-0.4311
103	W	H	-0.4210
104	G	H	0.0000
105	Q	H	-1.1113
106	G	H	-0.4053
107	T	H	0.0000
108	M	H	0.3572
109	V	H	0.0000
110	T	H	-0.2476
111	V	H	0.0000
112	S	H	-1.1050
2	S	L	0.0534
3	V	L	1.1257
4	L	L	0.0000
5	T	L	-0.0435
6	Q	L	0.0000
7	P	L	-0.5640
8	P	L	-0.8679
10	S	L	-0.9319
11	V	L	-0.3704
12	S	L	-0.4935
13	A	L	0.0000
14	A	L	-0.9827
15	P	L	-1.5019
16	G	L	-1.7853
17	Q	L	-2.2994
18	K	L	-2.5046
19	V	L	0.0000
20	T	L	-0.5031
21	I	L	0.0000
22	S	L	-0.2903
23	C	L	0.0000
24	S	L	-0.2766
25	G	L	-0.2533
26	S	L	-0.5407
27	S	L	-0.9163
28	S	L	-0.6450
29	D	L	0.0000
30	I	L	0.0000
30A	G	L	-1.1930
30B	N	L	-1.3802
31	N	L	-0.4373
32	Y	L	0.3269
33	V	L	0.0000
34	S	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	L	L	-0.4999
40	P	L	-0.4891
41	G	L	-0.4515
42	T	L	-0.5671
43	A	L	-0.5175
44	P	L	0.0000
45	K	L	-1.0552
46	L	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	0.0703
50	D	L	-0.5714
51	N	L	-1.1416
52	N	L	-2.1779
53	K	L	-2.4234
54	R	L	-1.5557
55	P	L	-0.6043
56	S	L	-0.5129
57	G	L	-0.7513
58	I	L	-0.8554
59	P	L	-1.2740
60	D	L	-2.3441
61	R	L	-1.6748
62	F	L	0.0000
63	S	L	-1.3656
64	G	L	-1.1826
65	S	L	-1.1142
66	K	L	-0.9874
67	S	L	-0.7887
68	G	L	-1.0421
69	T	L	-0.9453
70	S	L	-0.6701
71	A	L	0.0000
72	T	L	-0.5387
73	L	L	0.0000
74	G	L	-0.8192
75	I	L	0.0000
76	T	L	-1.8430
77	G	L	-1.7520
78	L	L	0.0000
79	Q	L	-1.8493
80	T	L	-1.2678
81	G	L	-1.1736
82	D	L	0.0000
83	E	L	-1.8149
84	A	L	0.0000
85	D	L	-1.2928
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	G	L	0.0000
90	T	L	0.0000
91	W	L	0.1671
92	D	L	0.0000
93	S	L	-0.2808
94	S	L	0.0480
95	L	L	0.2899
95A	S	L	0.0637
95B	A	L	0.0000
96	W	L	0.0000
97	V	L	0.0000
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-0.7312
101	G	L	-1.0228
102	T	L	0.0000
103	K	L	-2.0330
104	L	L	0.0000
105	T	L	-0.7412
106	V	L	0.0000
107	L	L	0.0597
108	R	L	-1.3408
109	T	L	-0.7368