Project name: Valen&Jordi_3o34:A

Chain sequence(s)	A: EDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.0984
• Maximal score value: 1.4145
• Average score: -0.949
• Total score value: -167.9758

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
826	E	A	-2.5479
827	D	A	-2.5921
828	W	A	-1.3345
829	C	A	0.0000
830	A	A	-0.6703
831	V	A	0.0565
832	C	A	0.1880
833	Q	A	-1.3095
834	N	A	-1.9079
835	G	A	-1.6119
836	G	A	-1.7341
837	E	A	-1.8689
838	L	A	-1.0928
839	L	A	0.0000
840	C	A	-1.4627
841	C	A	0.0000
842	E	A	-2.9997
843	K	A	-2.5234
844	C	A	-1.6288
845	P	A	-1.9887
846	K	A	-1.7089
847	V	A	0.0000
848	F	A	0.0000
849	H	A	-0.7048
850	L	A	-0.4107
851	S	A	-0.3100
852	C	A	0.0246
853	H	A	0.0000
854	V	A	0.0000
855	P	A	0.0000
856	T	A	-0.5994
857	L	A	0.0000
858	T	A	-0.6173
859	N	A	-0.9925
860	F	A	-0.1068
861	P	A	-0.9104
862	S	A	-0.9195
863	G	A	-1.5133
864	E	A	-2.6012
865	W	A	0.0000
866	I	A	0.0000
867	C	A	0.0000
868	T	A	0.0000
869	F	A	0.0387
870	C	A	-0.6804
871	R	A	0.0000
872	D	A	-1.8497
873	L	A	-1.0241
874	S	A	-1.3325
875	K	A	-2.5988
876	P	A	-2.3823
877	E	A	-2.9412
878	V	A	-2.3670
879	E	A	-2.6815
880	Y	A	0.0000
881	D	A	-1.6710
882	C	A	-1.1512
883	D	A	-1.7432
884	A	A	-1.2429
885	P	A	-0.8421
886	S	A	-0.9980
887	H	A	-1.1462
892	K	A	-2.7864
893	K	A	-3.0548
894	T	A	-1.9817
895	E	A	-2.3933
896	G	A	-1.1248
897	L	A	0.2322
898	V	A	1.0094
899	K	A	-0.5750
900	L	A	-0.5497
901	T	A	-0.3152
902	P	A	-0.3698
903	I	A	0.1982
904	D	A	-0.4507
905	K	A	-0.7398
906	R	A	-0.4453
907	K	A	-0.2684
908	C	A	0.0000
909	E	A	0.0000
910	R	A	-0.1102
911	L	A	0.0000
912	L	A	0.0000
913	L	A	0.0000
914	F	A	0.6876
915	L	A	0.0000
916	Y	A	0.0000
917	C	A	0.1370
918	H	A	-0.4580
919	E	A	-1.5283
920	M	A	-0.4407
921	S	A	0.0000
922	L	A	1.0251
923	A	A	0.1773
924	F	A	0.0000
925	Q	A	-0.4957
926	D	A	-1.6726
927	P	A	-0.7873
928	V	A	0.1980
929	P	A	0.4982
930	L	A	1.4145
931	T	A	0.6029
932	V	A	0.3939
933	P	A	-0.7522
934	D	A	-1.7514
935	Y	A	0.0000
936	Y	A	-0.7540
937	K	A	-2.0411
938	I	A	-1.1097
939	I	A	0.0000
940	K	A	-2.3488
941	N	A	-1.8905
942	P	A	-0.9580
943	M	A	-0.9146
944	D	A	0.0000
945	L	A	0.0000
946	S	A	-1.2580
947	T	A	-1.1839
948	I	A	0.0000
949	K	A	-1.4754
950	K	A	-2.5349
951	R	A	-1.7630
952	L	A	0.0000
953	Q	A	-2.2536
954	E	A	-2.7779
955	D	A	-2.2584
956	Y	A	0.0435
957	S	A	-0.5159
958	M	A	0.5301
959	Y	A	0.0000
960	S	A	-0.5526
961	K	A	-1.9556
962	P	A	-1.7186
963	E	A	-2.3788
964	D	A	-1.4691
965	F	A	0.0000
966	V	A	-1.0583
967	A	A	-0.9298
968	D	A	0.0000
969	F	A	0.0000
970	R	A	-1.4691
971	L	A	-0.8547
972	I	A	0.0000
973	F	A	0.0000
974	Q	A	-1.5536
975	N	A	0.0000
976	C	A	0.0000
977	A	A	-1.3895
978	E	A	-2.1154
979	F	A	-1.0947
980	N	A	-1.9201
981	E	A	-2.9044
982	P	A	-2.4992
983	D	A	-2.7261
984	S	A	-2.4454
985	E	A	-2.4684
986	V	A	-0.6681
987	A	A	0.0000
988	N	A	-1.5978
989	A	A	-0.8328
990	G	A	0.0000
991	I	A	-0.1211
992	K	A	-1.7574
993	L	A	0.0000
994	E	A	-1.9305
995	N	A	-2.2289
996	Y	A	-1.4740
997	F	A	0.0000
998	E	A	-2.4619
999	E	A	-3.0984
1000	L	A	-1.8199
1001	L	A	-1.7022
1002	K	A	-2.8156
1003	N	A	-2.3621
1004	L	A	-1.1431
1005	Y	A	-0.5713
1006	P	A	-0.9339