Project name: 2f0e0de7f1128b6

Chain sequence(s)	A: ASKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFSYGVQCFSRYPDHMKRHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAAGIT
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8567
• Maximal score value: 1.1478
• Average score: -0.8877
• Total score value: -203.2722

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-1.1892
2	S	A	-1.6361
3	K	A	-2.1535
4	G	A	0.0000
5	E	A	-1.6711
6	E	A	-2.1847
7	L	A	-0.7898
8	F	A	0.0000
9	T	A	-0.2766
10	G	A	0.3527
11	V	A	1.1478
12	V	A	0.0000
13	P	A	-1.0777
14	I	A	0.0000
15	L	A	-1.1451
16	V	A	0.0000
17	E	A	-1.9695
18	L	A	0.0000
19	D	A	-3.2345
20	G	A	-2.6860
21	D	A	-2.2561
22	V	A	0.0000
23	N	A	-1.7358
24	G	A	-1.2981
25	H	A	-1.7547
26	K	A	-2.6609
27	F	A	0.0000
28	S	A	-1.7808
29	V	A	0.0000
30	S	A	-1.1032
31	G	A	0.0000
32	E	A	-2.3894
33	G	A	-1.6691
34	E	A	-1.8322
35	G	A	0.0000
36	D	A	-0.0705
37	A	A	0.0000
38	T	A	0.2010
39	Y	A	0.9457
40	G	A	0.0000
41	K	A	-0.3113
42	L	A	0.0000
43	T	A	-0.8374
44	L	A	0.0000
45	K	A	-1.4131
46	F	A	0.0000
47	I	A	-1.1882
48	C	A	0.0000
49	T	A	-0.7562
50	T	A	-1.1681
51	G	A	-1.6714
52	K	A	-2.2941
53	L	A	0.0000
54	P	A	-1.1247
55	V	A	0.0000
56	P	A	0.0000
57	W	A	0.0000
58	P	A	0.0000
59	T	A	0.0000
60	L	A	0.0000
61	V	A	0.0000
62	T	A	0.0000
63	T	A	0.0000
64	F	A	0.0000
66	Y	A	0.0000
67	G	A	0.0000
68	V	A	0.0000
69	Q	A	0.0000
70	C	A	0.0000
71	F	A	0.0000
72	S	A	0.0000
73	R	A	-1.1939
74	Y	A	0.0000
75	P	A	-1.9160
76	D	A	-2.9456
77	H	A	-2.4335
78	M	A	0.0000
79	K	A	-2.7159
80	R	A	-2.8465
81	H	A	-1.7523
82	D	A	0.0000
83	F	A	0.0000
84	F	A	0.0000
85	K	A	0.0000
86	S	A	-0.9881
87	A	A	0.0000
88	M	A	0.0000
89	P	A	-0.9821
90	E	A	-1.5106
91	G	A	0.0000
92	Y	A	0.0000
93	V	A	-0.6400
94	Q	A	0.0000
95	E	A	-2.3118
96	R	A	0.0000
97	T	A	-0.4109
98	I	A	0.0000
99	F	A	0.3533
100	F	A	0.0000
101	K	A	-1.6964
102	D	A	-2.7567
103	D	A	-2.4870
104	G	A	0.0000
105	N	A	-0.6737
106	Y	A	0.0000
107	K	A	-1.6414
108	T	A	0.0000
109	R	A	-3.2572
110	A	A	0.0000
111	E	A	-1.7882
112	V	A	0.0000
113	K	A	-1.1704
114	F	A	-1.2973
115	E	A	-1.6267
116	G	A	-1.7398
117	D	A	-2.1493
118	T	A	-1.6307
119	L	A	0.0000
120	V	A	0.0000
121	N	A	0.0000
122	R	A	-2.2764
123	I	A	0.0000
124	E	A	-3.8368
125	L	A	0.0000
126	K	A	-2.2141
127	G	A	0.0000
128	I	A	-1.0711
129	D	A	-2.4546
130	F	A	0.0000
131	K	A	-3.7538
132	E	A	-3.8567
133	D	A	-3.5343
134	G	A	-2.8165
135	N	A	-2.2731
136	I	A	0.0000
137	L	A	-1.9608
138	G	A	-2.2813
139	H	A	-2.1895
140	K	A	-2.5242
141	L	A	0.0000
142	E	A	-1.9106
143	Y	A	-0.7715
144	N	A	-0.5996
145	Y	A	-0.7140
146	N	A	-0.9831
147	S	A	-0.9867
148	H	A	0.0000
149	N	A	-1.1421
150	V	A	0.0000
151	Y	A	0.1266
152	I	A	0.0000
153	M	A	-0.6841
154	A	A	-1.5409
155	D	A	0.0000
156	K	A	-3.0008
157	Q	A	-2.9712
158	K	A	-3.0391
159	N	A	-2.5268
160	G	A	0.0000
161	I	A	0.0000
162	K	A	-1.0474
163	V	A	0.0000
164	N	A	-0.4858
165	F	A	0.0000
166	K	A	-1.3367
167	I	A	0.0000
168	R	A	-1.0319
169	H	A	0.0000
170	N	A	-1.3311
171	I	A	0.0000
172	E	A	-3.3551
173	D	A	-3.0530
174	G	A	-1.8789
175	S	A	-0.8543
176	V	A	-0.0874
177	Q	A	0.0000
178	L	A	-0.5241
179	A	A	0.0000
180	D	A	0.0000
181	H	A	0.0000
182	Y	A	0.1044
183	Q	A	0.0000
184	Q	A	-1.1770
185	N	A	0.0000
186	T	A	-0.6533
187	P	A	-0.5954
188	I	A	0.0009
189	G	A	-1.0578
190	D	A	-1.9632
191	G	A	-1.2433
192	P	A	-0.7364
193	V	A	-0.4117
194	L	A	-0.4230
195	L	A	-0.7828
196	P	A	0.0000
197	D	A	-2.3653
198	N	A	-1.6314
199	H	A	0.0000
200	Y	A	-0.1438
201	L	A	0.0000
202	S	A	-0.6117
203	T	A	0.0000
204	Q	A	-1.1825
205	S	A	-0.4222
206	A	A	0.0075
207	L	A	-0.0534
208	S	A	-0.7149
209	K	A	-1.8615
210	D	A	-2.0403
211	P	A	-1.7828
212	N	A	-2.4207
213	E	A	-2.6574
214	K	A	-3.1974
215	R	A	-3.2156
216	D	A	-2.1852
217	H	A	0.0000
218	M	A	0.0000
219	V	A	-0.4900
220	L	A	0.0000
221	L	A	0.3305
222	E	A	0.0000
223	F	A	0.1997
224	V	A	0.0000
225	T	A	-0.4418
226	A	A	0.0000
227	A	A	-0.3692
228	G	A	-0.5877
229	I	A	-0.6219
230	T	A	-0.2112