Project name: 3gbm:L
Status: done
submitted: 2019-03-20 20:09:04, status changed: 2019-03-20 20:16:01
Settings
|
Chain sequence(s)
|
L: VLTQPPSVSAAPGQKVTISCSGSSSNIGNDYVSWYQQLPGTAPKLLIYDNNKRPSGIPDRFSGSKSGTSATLGITGLQTGDEANYYCATWDRTAYVVFGGGTKLTQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.2265
-
Maximal score value
-
2.3581
-
Average score
-
-0.8268
-
Total score value
-
-171.976
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 3 |
V |
L |
1.7462 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
0.1488 |
|
| 6 |
Q |
L |
-0.1923 |
|
| 7 |
P |
L |
-0.6298 |
|
| 8 |
P |
L |
-0.9032 |
|
| 9 |
S |
L |
-0.9193 |
|
| 11 |
V |
L |
-0.3791 |
|
| 12 |
S |
L |
-0.6775 |
|
| 13 |
A |
L |
-0.7314 |
|
| 14 |
A |
L |
-0.9863 |
|
| 15 |
P |
L |
-1.4215 |
|
| 16 |
G |
L |
-1.8421 |
|
| 17 |
Q |
L |
-2.5047 |
|
| 18 |
K |
L |
-2.5411 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.5344 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
S |
L |
-0.3007 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
S |
L |
-0.2364 |
|
| 25 |
G |
L |
-0.1076 |
|
| 26 |
S |
L |
-0.5261 |
|
| 27 |
S |
L |
-1.2558 |
|
| 27A |
S |
L |
-1.3969 |
|
| 27B |
N |
L |
-0.5392 |
|
| 28 |
I |
L |
0.0000 |
|
| 29 |
G |
L |
-1.2620 |
|
| 30 |
N |
L |
-1.5443 |
|
| 31 |
D |
L |
0.0000 |
|
| 32 |
Y |
L |
0.5030 |
|
| 33 |
V |
L |
0.0000 |
|
| 34 |
S |
L |
-0.0281 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
0.1927 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-0.9532 |
|
| 39 |
L |
L |
-0.6413 |
|
| 40 |
P |
L |
-0.6317 |
|
| 41 |
G |
L |
-0.5682 |
|
| 42 |
T |
L |
-0.4889 |
|
| 43 |
A |
L |
-0.3796 |
|
| 44 |
P |
L |
-0.6139 |
|
| 45 |
K |
L |
-0.7301 |
|
| 46 |
L |
L |
0.0287 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
-0.8364 |
|
| 50 |
D |
L |
-1.2141 |
|
| 51 |
N |
L |
-1.4192 |
|
| 52 |
N |
L |
-2.4727 |
|
| 53 |
K |
L |
-2.7447 |
|
| 54 |
R |
L |
-2.3552 |
|
| 55 |
P |
L |
-1.1352 |
|
| 56 |
S |
L |
-0.9628 |
|
| 57 |
G |
L |
-0.7892 |
|
| 58 |
I |
L |
-0.9113 |
|
| 59 |
P |
L |
-1.3479 |
|
| 60 |
D |
L |
-2.2702 |
|
| 61 |
R |
L |
-1.5788 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-1.5422 |
|
| 64 |
G |
L |
-1.2770 |
|
| 65 |
S |
L |
-1.1382 |
|
| 66 |
K |
L |
-0.8917 |
|
| 67 |
S |
L |
-0.7341 |
|
| 68 |
G |
L |
-0.8466 |
|
| 69 |
T |
L |
-0.9465 |
|
| 70 |
S |
L |
-0.6617 |
|
| 71 |
A |
L |
0.0000 |
|
| 72 |
T |
L |
-0.5405 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
G |
L |
-0.7239 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
T |
L |
-1.9550 |
|
| 77 |
G |
L |
-1.5994 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-2.0643 |
|
| 80 |
T |
L |
-1.4883 |
|
| 81 |
G |
L |
-1.4406 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
E |
L |
-2.5664 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
N |
L |
-1.3709 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.0065 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
A |
L |
0.0000 |
|
| 90 |
T |
L |
0.0000 |
|
| 91 |
W |
L |
1.0047 |
|
| 92 |
D |
L |
-0.1520 |
|
| 93 |
R |
L |
-1.7135 |
|
| 95 |
T |
L |
-0.4634 |
|
| 95B |
A |
L |
0.0931 |
|
| 95C |
Y |
L |
1.6175 |
|
| 96 |
V |
L |
2.3581 |
|
| 97 |
V |
L |
0.0000 |
|
| 98 |
F |
L |
1.8211 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
G |
L |
-0.0694 |
|
| 101 |
G |
L |
-0.6156 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-2.1093 |
|
| 104 |
L |
L |
0.0000 |
|
| 105 |
T |
L |
-1.0933 |
|
| 108 |
Q |
L |
-1.9439 |
|
| 109 |
P |
L |
-1.6673 |
|
| 110 |
K |
L |
-2.3509 |
|
| 111 |
A |
L |
-1.5011 |
|
| 112 |
A |
L |
-0.8060 |
|
| 113 |
P |
L |
-0.4575 |
|
| 114 |
S |
L |
-0.2768 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
T |
L |
0.2160 |
|
| 117 |
L |
L |
0.0000 |
|
| 118 |
F |
L |
1.7335 |
|
| 119 |
P |
L |
0.6957 |
|
| 120 |
P |
L |
0.0000 |
|
| 121 |
S |
L |
-1.0327 |
|
| 122 |
S |
L |
-1.8573 |
|
| 123 |
E |
L |
-2.9055 |
|
| 124 |
E |
L |
-2.4972 |
|
| 125 |
L |
L |
-2.2450 |
|
| 126 |
Q |
L |
-2.6662 |
|
| 127 |
A |
L |
-2.2350 |
|
| 128 |
N |
L |
-2.9172 |
|
| 129 |
K |
L |
-3.0634 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
T |
L |
-0.1448 |
|
| 132 |
L |
L |
0.0000 |
|
| 133 |
V |
L |
1.1154 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.9663 |
|
| 136 |
I |
L |
0.0000 |
|
| 137 |
S |
L |
-0.7054 |
|
| 138 |
D |
L |
-1.7567 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
-1.5752 |
|
| 141 |
P |
L |
-1.0618 |
|
| 142 |
G |
L |
-1.0454 |
|
| 143 |
A |
L |
-0.2102 |
|
| 144 |
V |
L |
-0.1292 |
|
| 145 |
T |
L |
-0.1157 |
|
| 146 |
V |
L |
0.1543 |
|
| 147 |
A |
L |
-0.3951 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-1.0748 |
|
| 150 |
A |
L |
0.0000 |
|
| 151 |
D |
L |
-1.6456 |
|
| 152 |
S |
L |
-1.0160 |
|
| 153 |
S |
L |
-0.6715 |
|
| 154 |
P |
L |
-0.8825 |
|
| 155 |
V |
L |
-0.8334 |
|
| 156 |
K |
L |
-1.8046 |
|
| 157 |
A |
L |
-1.0085 |
|
| 158 |
G |
L |
-0.9294 |
|
| 159 |
V |
L |
-0.8966 |
|
| 160 |
E |
L |
-1.7850 |
|
| 161 |
T |
L |
-0.6221 |
|
| 162 |
T |
L |
-0.5027 |
|
| 163 |
T |
L |
-0.3404 |
|
| 164 |
P |
L |
-0.6380 |
|
| 165 |
S |
L |
-1.4605 |
|
| 166 |
K |
L |
-2.7508 |
|
| 167 |
Q |
L |
-2.3414 |
|
| 168 |
S |
L |
-1.7797 |
|
| 169 |
N |
L |
-2.6143 |
|
| 170 |
N |
L |
-3.0594 |
|
| 172 |
K |
L |
-2.8399 |
|
| 173 |
Y |
L |
-1.7101 |
|
| 174 |
A |
L |
-0.8662 |
|
| 175 |
A |
L |
-0.1996 |
|
| 176 |
S |
L |
0.0635 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
Y |
L |
0.2917 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
S |
L |
-0.6415 |
|
| 181 |
L |
L |
-1.0961 |
|
| 182 |
T |
L |
-1.8157 |
|
| 183 |
P |
L |
-2.5432 |
|
| 184 |
E |
L |
-3.1737 |
|
| 185 |
Q |
L |
-2.2311 |
|
| 186 |
W |
L |
0.0000 |
|
| 187 |
K |
L |
-3.2265 |
|
| 188 |
S |
L |
-2.3725 |
|
| 189 |
H |
L |
-2.4328 |
|
| 190 |
R |
L |
-2.8250 |
|
| 191 |
S |
L |
0.0000 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
S |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
Q |
L |
-0.9010 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-0.6467 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
E |
L |
-2.3111 |
|
| 200 |
G |
L |
-1.4006 |
|
| 203 |
S |
L |
-1.0210 |
|
| 204 |
T |
L |
-0.6656 |
|
| 205 |
V |
L |
-0.5570 |
|
| 206 |
E |
L |
-1.7450 |
|
| 207 |
K |
L |
-1.2642 |
|
| 208 |
T |
L |
-0.8387 |
|
| 209 |
V |
L |
-0.3102 |
|
| 210 |
A |
L |
-1.2681 |
|
| 211 |
P |
L |
-1.6251 |
|
| 212 |
T |
L |
-1.2045 |
|
| 213 |
E |
L |
-2.2722 |
|