Project name: 5i5k:L
Status: done
submitted: 2019-03-21 14:44:41, status changed: 2019-03-21 14:51:53
Settings
|
Chain sequence(s)
|
L: DIQMTQSPSSLSASVGDRVTITCGASENIYGALNWYQQKPGKAPKLLIYGATNLADGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQNVLNTPLTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
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Minimal score value
-
-3.492
-
Maximal score value
-
2.1112
-
Average score
-
-0.7122
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Total score value
-
-151.7069
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
D |
L |
-2.4958 |
|
| 2 |
I |
L |
0.0000 |
|
| 3 |
Q |
L |
-1.6606 |
|
| 4 |
M |
L |
0.0000 |
|
| 5 |
T |
L |
-0.6888 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-0.4991 |
|
| 8 |
P |
L |
-0.5979 |
|
| 9 |
S |
L |
-0.7986 |
|
| 10 |
S |
L |
-0.6547 |
|
| 11 |
L |
L |
-0.2268 |
|
| 12 |
S |
L |
-1.0260 |
|
| 13 |
A |
L |
0.0000 |
|
| 14 |
S |
L |
-0.6215 |
|
| 15 |
V |
L |
0.7029 |
|
| 16 |
G |
L |
-0.3027 |
|
| 17 |
D |
L |
-1.2552 |
|
| 18 |
R |
L |
-1.9467 |
|
| 19 |
V |
L |
-0.9176 |
|
| 20 |
T |
L |
-0.4073 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.4942 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
G |
L |
-1.4655 |
|
| 25 |
A |
L |
-1.5187 |
|
| 26 |
S |
L |
-2.1678 |
|
| 27 |
E |
L |
-2.8263 |
|
| 28 |
N |
L |
-1.4709 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
Y |
L |
0.5188 |
|
| 31 |
G |
L |
0.3043 |
|
| 32 |
A |
L |
0.6859 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
N |
L |
0.3965 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0021 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5465 |
|
| 39 |
K |
L |
-2.2778 |
|
| 40 |
P |
L |
-1.5247 |
|
| 41 |
G |
L |
-1.7134 |
|
| 42 |
K |
L |
-2.5825 |
|
| 43 |
A |
L |
-1.5879 |
|
| 44 |
P |
L |
-1.5912 |
|
| 45 |
K |
L |
-1.7720 |
|
| 46 |
L |
L |
-0.2470 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
Y |
L |
0.3383 |
|
| 50 |
G |
L |
-0.1939 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
T |
L |
-0.7675 |
|
| 53 |
N |
L |
-1.2474 |
|
| 54 |
L |
L |
-0.5223 |
|
| 55 |
A |
L |
-0.9653 |
|
| 56 |
D |
L |
-1.9215 |
|
| 57 |
G |
L |
-1.1772 |
|
| 58 |
V |
L |
-0.9528 |
|
| 59 |
P |
L |
-0.9980 |
|
| 60 |
S |
L |
-0.9762 |
|
| 61 |
R |
L |
-1.7833 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.8867 |
|
| 64 |
G |
L |
-0.4563 |
|
| 65 |
S |
L |
-0.8593 |
|
| 66 |
G |
L |
-0.7290 |
|
| 67 |
S |
L |
-0.6454 |
|
| 68 |
G |
L |
-0.9168 |
|
| 69 |
T |
L |
-1.5768 |
|
| 70 |
D |
L |
-2.1576 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.6538 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.7385 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
S |
L |
-1.5568 |
|
| 77 |
S |
L |
-1.0865 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
Q |
L |
-0.9227 |
|
| 80 |
P |
L |
-0.8616 |
|
| 81 |
E |
L |
-2.0692 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
F |
L |
-0.4784 |
|
| 84 |
A |
L |
-0.9182 |
|
| 85 |
T |
L |
-0.6472 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.1233 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
Q |
L |
0.0000 |
|
| 90 |
N |
L |
0.0000 |
|
| 91 |
V |
L |
2.0985 |
|
| 92 |
L |
L |
1.6888 |
|
| 93 |
N |
L |
-0.2275 |
|
| 94 |
T |
L |
0.1187 |
|
| 95 |
P |
L |
0.1482 |
|
| 96 |
L |
L |
1.7187 |
|
| 97 |
T |
L |
1.1287 |
|
| 98 |
F |
L |
1.2864 |
|
| 99 |
G |
L |
-0.1286 |
|
| 100 |
Q |
L |
-0.9681 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.1361 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
E |
L |
-0.9589 |
|
| 106 |
I |
L |
-0.4956 |
|
| 107 |
K |
L |
-1.1766 |
|
| 108 |
R |
L |
-1.6696 |
|
| 109 |
T |
L |
-0.3309 |
|
| 110 |
V |
L |
1.0456 |
|
| 111 |
A |
L |
0.2457 |
|
| 112 |
A |
L |
0.0635 |
|
| 113 |
P |
L |
-0.0271 |
|
| 114 |
S |
L |
0.1475 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
2.1112 |
|
| 117 |
I |
L |
1.8906 |
|
| 118 |
F |
L |
1.9689 |
|
| 119 |
P |
L |
0.6593 |
|
| 120 |
P |
L |
-0.4940 |
|
| 121 |
S |
L |
-1.8010 |
|
| 122 |
D |
L |
-3.2289 |
|
| 123 |
E |
L |
-3.4568 |
|
| 124 |
Q |
L |
-2.5500 |
|
| 125 |
L |
L |
-2.2555 |
|
| 126 |
K |
L |
-2.9630 |
|
| 127 |
S |
L |
-1.7920 |
|
| 128 |
G |
L |
-1.2692 |
|
| 129 |
T |
L |
-0.8219 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.1047 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.9464 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.9632 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.4382 |
|
| 138 |
N |
L |
-1.1124 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.2201 |
|
| 142 |
R |
L |
-1.7853 |
|
| 143 |
E |
L |
-2.4496 |
|
| 144 |
A |
L |
-2.0462 |
|
| 145 |
K |
L |
-2.2417 |
|
| 146 |
V |
L |
-1.3111 |
|
| 147 |
Q |
L |
-0.9299 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-1.1891 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-1.9879 |
|
| 152 |
N |
L |
-1.5944 |
|
| 153 |
A |
L |
-0.5346 |
|
| 154 |
L |
L |
0.5190 |
|
| 155 |
Q |
L |
-0.0941 |
|
| 156 |
S |
L |
-0.5431 |
|
| 157 |
G |
L |
-0.9417 |
|
| 158 |
N |
L |
-1.0500 |
|
| 159 |
S |
L |
-1.3399 |
|
| 160 |
Q |
L |
-2.1276 |
|
| 161 |
E |
L |
-1.5898 |
|
| 162 |
S |
L |
-0.3556 |
|
| 163 |
V |
L |
0.4783 |
|
| 164 |
T |
L |
-0.5349 |
|
| 165 |
E |
L |
-1.8379 |
|
| 166 |
Q |
L |
-1.8983 |
|
| 167 |
D |
L |
-2.1277 |
|
| 168 |
S |
L |
-1.8821 |
|
| 169 |
K |
L |
-2.3307 |
|
| 170 |
D |
L |
-1.8521 |
|
| 171 |
S |
L |
-1.9075 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.6513 |
|
| 175 |
L |
L |
0.0000 |
|
| 176 |
S |
L |
0.0191 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.5683 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.3863 |
|
| 181 |
L |
L |
-0.3081 |
|
| 182 |
S |
L |
-0.8447 |
|
| 183 |
K |
L |
-1.9057 |
|
| 184 |
A |
L |
-1.5394 |
|
| 185 |
D |
L |
-2.0776 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.4920 |
|
| 188 |
K |
L |
-3.4359 |
|
| 189 |
H |
L |
-2.8569 |
|
| 190 |
K |
L |
-2.7248 |
|
| 191 |
V |
L |
-0.7634 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
-0.8988 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-1.1388 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.0006 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.5397 |
|
| 200 |
G |
L |
-0.2319 |
|
| 201 |
L |
L |
-0.1324 |
|
| 202 |
S |
L |
-0.4598 |
|
| 203 |
S |
L |
-0.3737 |
|
| 204 |
P |
L |
-0.4851 |
|
| 205 |
V |
L |
0.1823 |
|
| 206 |
T |
L |
-0.3782 |
|
| 207 |
K |
L |
-0.1593 |
|
| 208 |
S |
L |
0.0552 |
|
| 209 |
F |
L |
0.1833 |
|
| 210 |
N |
L |
-1.6153 |
|
| 211 |
R |
L |
-2.2891 |
|
| 212 |
G |
L |
-2.0992 |
|
| 213 |
E |
L |
-2.6336 |
|