Project name: 32b48a7797e0507

Chain sequence(s)	A: PTITGNLENQTTSIGESIEVSCTASPQIMWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACCAKVEAFFIIEG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.6643
• Maximal score value: 0.5651
• Average score: -1.3202
• Total score value: -108.2545

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
667	P	A	-0.2416
668	T	A	-0.3187
669	I	A	-0.3556
670	T	A	-0.6019
671	G	A	-1.3874
672	N	A	-2.4153
673	L	A	0.0000
674	E	A	-3.0995
675	N	A	-2.3004
676	Q	A	-1.1058
677	T	A	-0.6685
678	T	A	-1.0215
679	S	A	-1.6025
680	I	A	-1.6461
681	G	A	-2.6334
682	E	A	-3.0564
683	S	A	-2.7582
684	I	A	0.0000
685	E	A	-2.3385
686	V	A	0.0000
687	S	A	-2.0478
688	C	A	0.0000
689	T	A	-1.1344
690	A	A	-0.6818
691	S	A	-0.4439
696	P	A	-0.6889
697	Q	A	-1.3593
698	I	A	0.0000
699	M	A	-0.2023
700	W	A	0.0000
701	F	A	-1.2871
702	K	A	-1.9145
703	D	A	-2.9067
704	N	A	-3.2032
705	E	A	-2.7247
706	T	A	-1.1263
707	L	A	-0.5497
708	V	A	0.3024
709	E	A	-1.5470
710	D	A	-1.8680
711	S	A	-1.5230
712	G	A	-2.0735
713	I	A	0.0000
714	V	A	-1.2497
715	L	A	-1.6460
716	K	A	-3.1132
717	D	A	-3.3855
718	G	A	-2.6185
719	N	A	-2.5153
720	R	A	-2.6374
721	N	A	-2.6237
722	L	A	0.0000
723	T	A	-1.4200
724	I	A	0.0000
725	R	A	-3.6037
726	R	A	-3.6643
727	V	A	0.0000
728	R	A	-3.6526
729	K	A	-3.3433
730	E	A	-3.1536
731	D	A	-2.1421
732	E	A	-1.8722
733	G	A	0.0000
734	L	A	-1.0060
735	Y	A	0.0000
736	T	A	0.0000
737	C	A	0.0000
738	Q	A	-0.6475
739	A	A	0.0000
740	C	A	0.4324
745	C	A	0.5651
746	A	A	-0.3096
747	K	A	-1.6182
748	V	A	-1.6733
749	E	A	-2.4192
750	A	A	0.0000
751	F	A	-0.4648
752	F	A	0.0000
753	I	A	-0.4649
754	I	A	0.0000
755	E	A	-2.1191
756	G	A	-1.3573