Project name: 4g5z:L
Status: done
submitted: 2019-03-20 20:15:20, status changed: 2019-03-20 20:29:05
Settings
|
Chain sequence(s)
|
L: EIVLTQSPDFQSVTPKEKVTITCRASQSIGSSLHWYQQKPDQSPKLLIKYASQSFSGVPSRFSGSGSGTDFTLTINSLEAEDAAAYYCHQSSSLPFTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRG
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.8841
-
Maximal score value
-
2.6565
-
Average score
-
-0.7824
-
Total score value
-
-165.8674
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
L |
-0.9181 |
|
| 2 |
I |
L |
0.5451 |
|
| 3 |
V |
L |
1.4427 |
|
| 4 |
L |
L |
0.0000 |
|
| 5 |
T |
L |
-0.1572 |
|
| 6 |
Q |
L |
0.0000 |
|
| 7 |
S |
L |
-1.0551 |
|
| 8 |
P |
L |
-1.1055 |
|
| 9 |
D |
L |
-2.0193 |
|
| 10 |
F |
L |
-1.2899 |
|
| 11 |
Q |
L |
-1.0122 |
|
| 12 |
S |
L |
-0.7743 |
|
| 13 |
V |
L |
0.0000 |
|
| 14 |
T |
L |
-1.9374 |
|
| 15 |
P |
L |
-2.6051 |
|
| 16 |
K |
L |
-3.6120 |
|
| 17 |
E |
L |
-3.8841 |
|
| 18 |
K |
L |
-3.2332 |
|
| 19 |
V |
L |
0.0000 |
|
| 20 |
T |
L |
-0.6132 |
|
| 21 |
I |
L |
0.0000 |
|
| 22 |
T |
L |
-0.9918 |
|
| 23 |
C |
L |
0.0000 |
|
| 24 |
R |
L |
-2.1043 |
|
| 25 |
A |
L |
0.0000 |
|
| 26 |
S |
L |
-0.9203 |
|
| 27 |
Q |
L |
-1.6940 |
|
| 28 |
S |
L |
-1.4300 |
|
| 29 |
I |
L |
0.0000 |
|
| 30 |
G |
L |
-0.8134 |
|
| 31 |
S |
L |
-0.5207 |
|
| 32 |
S |
L |
-0.0496 |
|
| 33 |
L |
L |
0.0000 |
|
| 34 |
H |
L |
0.0000 |
|
| 35 |
W |
L |
0.0000 |
|
| 36 |
Y |
L |
-0.0687 |
|
| 37 |
Q |
L |
0.0000 |
|
| 38 |
Q |
L |
-1.5527 |
|
| 39 |
K |
L |
-2.0367 |
|
| 40 |
P |
L |
-2.1085 |
|
| 41 |
D |
L |
-2.6755 |
|
| 42 |
Q |
L |
-2.6381 |
|
| 43 |
S |
L |
-1.7680 |
|
| 44 |
P |
L |
-1.5437 |
|
| 45 |
K |
L |
-1.4193 |
|
| 46 |
L |
L |
-0.3093 |
|
| 47 |
L |
L |
0.0000 |
|
| 48 |
I |
L |
0.0000 |
|
| 49 |
K |
L |
-0.1169 |
|
| 50 |
Y |
L |
0.4607 |
|
| 51 |
A |
L |
0.0000 |
|
| 52 |
S |
L |
-0.6657 |
|
| 53 |
Q |
L |
-0.9076 |
|
| 54 |
S |
L |
-0.3959 |
|
| 55 |
F |
L |
0.2459 |
|
| 56 |
S |
L |
-0.0706 |
|
| 57 |
G |
L |
-0.2741 |
|
| 58 |
V |
L |
-0.0931 |
|
| 59 |
P |
L |
-0.2674 |
|
| 60 |
S |
L |
-0.5690 |
|
| 61 |
R |
L |
-1.2893 |
|
| 62 |
F |
L |
0.0000 |
|
| 63 |
S |
L |
-0.7961 |
|
| 64 |
G |
L |
-0.5618 |
|
| 65 |
S |
L |
-0.7962 |
|
| 66 |
G |
L |
-1.1698 |
|
| 67 |
S |
L |
-1.0101 |
|
| 68 |
G |
L |
-1.4470 |
|
| 69 |
T |
L |
-2.0022 |
|
| 70 |
D |
L |
-2.7316 |
|
| 71 |
F |
L |
0.0000 |
|
| 72 |
T |
L |
-0.8513 |
|
| 73 |
L |
L |
0.0000 |
|
| 74 |
T |
L |
-0.8194 |
|
| 75 |
I |
L |
0.0000 |
|
| 76 |
N |
L |
-2.9446 |
|
| 77 |
S |
L |
-3.1843 |
|
| 78 |
L |
L |
0.0000 |
|
| 79 |
E |
L |
-3.0011 |
|
| 80 |
A |
L |
-1.8843 |
|
| 81 |
E |
L |
-2.3334 |
|
| 82 |
D |
L |
0.0000 |
|
| 83 |
A |
L |
-1.1928 |
|
| 84 |
A |
L |
0.0000 |
|
| 85 |
A |
L |
0.0000 |
|
| 86 |
Y |
L |
0.0000 |
|
| 87 |
Y |
L |
0.3238 |
|
| 88 |
C |
L |
0.0000 |
|
| 89 |
H |
L |
1.3630 |
|
| 90 |
Q |
L |
0.0000 |
|
| 91 |
S |
L |
1.0032 |
|
| 92 |
S |
L |
0.2181 |
|
| 93 |
S |
L |
0.7122 |
|
| 94 |
L |
L |
1.7172 |
|
| 95 |
P |
L |
1.2182 |
|
| 96 |
F |
L |
2.6565 |
|
| 97 |
T |
L |
2.1215 |
|
| 98 |
F |
L |
2.5877 |
|
| 99 |
G |
L |
0.0000 |
|
| 100 |
P |
L |
0.0466 |
|
| 101 |
G |
L |
0.0000 |
|
| 102 |
T |
L |
0.0000 |
|
| 103 |
K |
L |
-1.3448 |
|
| 104 |
V |
L |
0.0000 |
|
| 105 |
D |
L |
0.0000 |
|
| 106 |
I |
L |
-1.1346 |
|
| 107 |
K |
L |
-1.2150 |
|
| 108 |
R |
L |
-0.9175 |
|
| 109 |
T |
L |
-0.0437 |
|
| 110 |
V |
L |
0.4837 |
|
| 111 |
A |
L |
-0.0172 |
|
| 112 |
A |
L |
-0.2490 |
|
| 113 |
P |
L |
0.0000 |
|
| 114 |
S |
L |
0.0066 |
|
| 115 |
V |
L |
0.0000 |
|
| 116 |
F |
L |
1.8612 |
|
| 117 |
I |
L |
0.0000 |
|
| 118 |
F |
L |
1.2143 |
|
| 119 |
P |
L |
-0.2699 |
|
| 120 |
P |
L |
-0.7980 |
|
| 121 |
S |
L |
-1.7949 |
|
| 122 |
D |
L |
-3.1969 |
|
| 123 |
E |
L |
-3.4094 |
|
| 124 |
Q |
L |
-2.4114 |
|
| 125 |
L |
L |
-2.4095 |
|
| 126 |
K |
L |
-2.9809 |
|
| 127 |
S |
L |
-1.8460 |
|
| 128 |
G |
L |
-1.3565 |
|
| 129 |
T |
L |
-1.0927 |
|
| 130 |
A |
L |
0.0000 |
|
| 131 |
S |
L |
0.0217 |
|
| 132 |
V |
L |
0.0000 |
|
| 133 |
V |
L |
0.7351 |
|
| 134 |
C |
L |
0.0000 |
|
| 135 |
L |
L |
0.7599 |
|
| 136 |
L |
L |
0.0000 |
|
| 137 |
N |
L |
-0.5914 |
|
| 138 |
N |
L |
-1.2237 |
|
| 139 |
F |
L |
0.0000 |
|
| 140 |
Y |
L |
0.0000 |
|
| 141 |
P |
L |
-1.1391 |
|
| 142 |
R |
L |
-1.6238 |
|
| 143 |
E |
L |
-2.5407 |
|
| 144 |
A |
L |
-1.7630 |
|
| 145 |
K |
L |
-2.2832 |
|
| 146 |
V |
L |
-1.0746 |
|
| 147 |
Q |
L |
-0.4570 |
|
| 148 |
W |
L |
0.0000 |
|
| 149 |
K |
L |
-0.5189 |
|
| 150 |
V |
L |
0.0000 |
|
| 151 |
D |
L |
-2.0201 |
|
| 152 |
N |
L |
-1.4626 |
|
| 153 |
A |
L |
-0.3151 |
|
| 154 |
L |
L |
0.7238 |
|
| 155 |
Q |
L |
-0.2306 |
|
| 156 |
S |
L |
-0.6186 |
|
| 157 |
G |
L |
-1.3508 |
|
| 158 |
N |
L |
-1.6584 |
|
| 159 |
S |
L |
-1.7333 |
|
| 160 |
Q |
L |
-2.4069 |
|
| 161 |
E |
L |
-2.1712 |
|
| 162 |
S |
L |
-0.5022 |
|
| 163 |
V |
L |
0.7504 |
|
| 164 |
T |
L |
-0.3902 |
|
| 165 |
E |
L |
-1.8052 |
|
| 166 |
Q |
L |
-1.7153 |
|
| 167 |
D |
L |
-2.0823 |
|
| 168 |
S |
L |
-1.9805 |
|
| 169 |
K |
L |
-2.4343 |
|
| 170 |
D |
L |
-2.1084 |
|
| 171 |
S |
L |
-1.8872 |
|
| 172 |
T |
L |
0.0000 |
|
| 173 |
Y |
L |
0.0000 |
|
| 174 |
S |
L |
-0.4132 |
|
| 175 |
L |
L |
-0.1756 |
|
| 176 |
S |
L |
0.0030 |
|
| 177 |
S |
L |
0.0000 |
|
| 178 |
T |
L |
-0.7714 |
|
| 179 |
L |
L |
0.0000 |
|
| 180 |
T |
L |
-0.7102 |
|
| 181 |
L |
L |
-0.8662 |
|
| 182 |
S |
L |
-1.0557 |
|
| 183 |
K |
L |
-2.0679 |
|
| 184 |
A |
L |
-1.8911 |
|
| 185 |
D |
L |
-2.5971 |
|
| 186 |
Y |
L |
0.0000 |
|
| 187 |
E |
L |
-3.7322 |
|
| 188 |
K |
L |
-3.5707 |
|
| 189 |
H |
L |
-3.1413 |
|
| 190 |
K |
L |
-3.2929 |
|
| 191 |
V |
L |
-1.8583 |
|
| 192 |
Y |
L |
0.0000 |
|
| 193 |
A |
L |
0.0000 |
|
| 194 |
C |
L |
0.0000 |
|
| 195 |
E |
L |
-0.6735 |
|
| 196 |
V |
L |
0.0000 |
|
| 197 |
T |
L |
-1.0914 |
|
| 198 |
H |
L |
0.0000 |
|
| 199 |
Q |
L |
-1.4384 |
|
| 200 |
G |
L |
-0.4021 |
|
| 201 |
L |
L |
-0.1628 |
|
| 202 |
S |
L |
-0.4175 |
|
| 203 |
S |
L |
-0.3293 |
|
| 204 |
P |
L |
-0.4187 |
|
| 205 |
V |
L |
0.0654 |
|
| 206 |
T |
L |
-0.3609 |
|
| 207 |
K |
L |
-0.5218 |
|
| 208 |
S |
L |
-0.6167 |
|
| 209 |
F |
L |
-1.0104 |
|
| 210 |
N |
L |
-2.2758 |
|
| 211 |
R |
L |
-2.6619 |
|
| 212 |
G |
L |
-1.8166 |
|